| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dimitar Bakalov, Petar Iliev, Zafer Sabit, Radka Tafradjiiska-Hadjiolova, Georgeta Bochev. Attenuation of Hypothyroidism-Induced Cognitive Impairment by Modulating Serotonin Mediation. Veterinary sciences. vol 10. issue 2. 2023-02-28. PMID:36851426. |
a staggering amount of research is suggesting that the common denominators in the pathophysiology of depression and the behavior changes in hypothyroidism are the hippocampal complex and the distorted serotonin metabolism. |
2023-02-28 |
2023-08-14 |
rat |
| Dimitar Bakalov, Petar Iliev, Zafer Sabit, Radka Tafradjiiska-Hadjiolova, Georgeta Bochev. Attenuation of Hypothyroidism-Induced Cognitive Impairment by Modulating Serotonin Mediation. Veterinary sciences. vol 10. issue 2. 2023-02-28. PMID:36851426. |
current results are promising and may serve as groundwork for further investigation of functional and structural changes in the hippocampus during a hypothyroid state, and in particular, the effects of serotonin mediation in hypothyroid-associated depressive-like behavior. |
2023-02-28 |
2023-08-14 |
rat |
| M Maetzi Estévez-Cabrera, Fausto Sánchez-Muñoz, Gilberto Pérez-Sánchez, Lenin Pavón, Adrian Hernández-Díazcouder, J Luis Córtes Altamirano, C Soria-Fregoso, Alfonso Alfaro-Rodríguez, Herlinda Bonilla-Jaim. Therapeutic treatment with fluoxetine using the chronic unpredictable stress model induces changes in neurotransmitters and circulating miRNAs in extracellular vesicles. Heliyon. vol 9. issue 2. 2023-02-28. PMID:36852042. |
after cums, the rats performed the fst, and serum levels of cort and six micrornas (mir-16, -21, -144, -155, -146a, -223) were analyzed, as were levels of dopamine, noradrenaline, and serotonin in the prefrontal cortex, hippocampus, and hypothalamus. |
2023-02-28 |
2023-08-14 |
rat |
| Paulina Surowka, Karolina Noworyta, Irena Smaga, Malgorzata Filip, Rafal Rygul. Trait sensitivity to negative feedback in rats is associated with increased expression of serotonin 5-HT Frontiers in molecular neuroscience. vol 16. 2023-02-27. PMID:36846570. |
as serotonin has been identified as an important modulator of sensitivity to feedback and because the hippocampus has been implicated in the mediation of learning from positive and negative outcomes, the present study aimed to identify differences in the expression of various genes encoding 5-ht receptors in this brain region between the rats displaying trait sensitivity and insensitivity to negative feedback. |
2023-02-27 |
2023-08-14 |
rat |
| Min-Kyung Joo, Xiaoyang Ma, Jong-Wook Yoo, Yoon-Jung Shin, Hyo-Jong Kim, Dong-Hyun Ki. Patient-derived Enterococcus mundtii and its capsular polysaccharides cause depression through the downregulation of NF-κB-involved serotonin and BDNF expression. Microbes and infection. 2023-02-09. PMID:36758891. |
nk1516 also caused the most potent depression-like behaviors in the absence of sickness behaviors, neuroinflammation, downregulated brain-derived neurotrophic factor (bdnf), and serotonin (5-ht) levels in the hippocampus of mice. |
2023-02-09 |
2023-08-14 |
mouse |
| Min-Kyung Joo, Xiaoyang Ma, Jong-Wook Yoo, Yoon-Jung Shin, Hyo-Jong Kim, Dong-Hyun Ki. Patient-derived Enterococcus mundtii and its capsular polysaccharides cause depression through the downregulation of NF-κB-involved serotonin and BDNF expression. Microbes and infection. 2023-02-09. PMID:36758891. |
its capsular polysaccharide (cp), but not cytoplasmic components, also caused depression-like behaviors and reduced bdnf and serotonin levels in the hippocampus. |
2023-02-09 |
2023-08-14 |
mouse |
| Subin Mao, Catherine Fonder, Md Fazlay Rubby, Gregory J Phillips, Donald S Sakaguchi, Long Qu. An integrated microfluidic chip for studying the effects of neurotransmitters on neurospheroids. Lab on a chip. 2023-02-08. PMID:36751868. |
to improve our understanding of how the central nervous system functions in health and disease, we report the development of an integrated chip for studying the effects of the neurotransmitters dopamine and serotonin on adult rat hippocampal progenitor cell (ahpc) neurospheroids. |
2023-02-08 |
2023-08-14 |
rat |
| Simin Afshar, Siamak Shahidi, Hemen Baooshi, Mahdieh Hoseini, Mahsa Esmaeili, Nasrin Hashemi-Firouzi, Alireza Komak. The role of hippocampal 5-HT Naunyn-Schmiedeberg's archives of pharmacology. 2023-02-07. PMID:36749399. |
the role of hippocampal 5-ht serotonin is a neurotransmitter, which is involved in memory via its receptors. |
2023-02-07 |
2023-08-14 |
Not clear |
| Lili Zou, Yaling Tian, Yuanfei Wang, Dongliang Chen, Xiaomin Lu, Ze Zeng, Zumin Chen, Chenli Lin, Yinji Lian. High-cholesterol diet promotes depression- and anxiety-like behaviors in mice by impact gut microbe and neuroinflammation. Journal of affective disorders. 2023-02-04. PMID:36738999. |
the concentration of 5-ht increased in the hippocampus, meanwhile, the expression of 5-ht receptor htr2a was distinct in different regions of the brain tissue. |
2023-02-04 |
2023-08-14 |
mouse |
| Lili Zou, Yaling Tian, Yuanfei Wang, Dongliang Chen, Xiaomin Lu, Ze Zeng, Zumin Chen, Chenli Lin, Yinji Lian. High-cholesterol diet promotes depression- and anxiety-like behaviors in mice by impact gut microbe and neuroinflammation. Journal of affective disorders. 2023-02-04. PMID:36738999. |
further, pearson correlation analysis showed that akkermansia_muciniphila was significantly negatively correlated with the concentration of mcp-1, il-17a in serum and 5-ht in hippocampal. |
2023-02-04 |
2023-08-14 |
mouse |
| Laura C Fox, Jamie L Scholl, Michael J Watt, Gina L Forste. GABA Neuroscience. 2023-02-03. PMID:36736883. |
the hippocampus and amygdala are implicated in stress responses and anxiety, and within these regions, gamma-aminobutyric acid (gaba) and serotonin modulate output and behavioral expression. |
2023-02-03 |
2023-08-14 |
Not clear |
| Mareli Roets, Linda Brand, Stephan F Stey. Increased depressive-like behaviour of postpartum Flinders sensitive and resistant line rats is reversed by a predictable postpartum stressor. Behavioural brain research. 2023-01-31. PMID:36720349. |
regardless of strain, pregnancy decreased time spent in the open arms of the elevated plus maze and hippocampal serotonin concentrations. |
2023-01-31 |
2023-08-14 |
rat |
| Mareli Roets, Linda Brand, Stephan F Stey. Increased depressive-like behaviour of postpartum Flinders sensitive and resistant line rats is reversed by a predictable postpartum stressor. Behavioural brain research. 2023-01-31. PMID:36720349. |
msew reversed these behaviours in both strains and increased social interaction with a male counterpart in the fsl rats, without influencing hippocampal or cortical serotonin or norepinephrine. |
2023-01-31 |
2023-08-14 |
rat |
| Nan Nan, Qi Wang, Mei-Jing Li, Yong-Song Xu, Xiao-Meng Guo, Rui Xu, Zhe Ma, Si-Hui Wang, Jing Li, Hui Zhao, Mu-Xin Gon. The Microbiota-Dependent Treatment of Wuzhuyu Decoction for Chronic Migraine Model Rat Associated with Anxiety-Depression Like Behavior. Oxidative medicine and cellular longevity. vol 2023. 2023-01-17. PMID:36647428. |
the cm rats exhibited anxiety- and depression-like behavior with 5-ht and number of neurons decreased in the ca1 and ca2 regions of hippocampal. |
2023-01-17 |
2023-08-14 |
rat |
| Pan Meng, Xi Zhang, Dandan Li, Hui Yang, Xiaoyuan Lin, Hongqing Zhao, Ping Li, Yuhong Wang, Xiaoye Wang, Jinwen G. Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis. Neural plasticity. vol 2023. 2023-01-17. PMID:36647544. |
western blot was utilized to measure the expression of bdnf and 5-ht in the hippocampus. |
2023-01-17 |
2023-08-14 |
rat |
| Kristi Liiver, Sophie Imbeault, Marianna Školnaja, Tanel Kaart, Margus Kanarik, Karita Laugus, Jade De Wettinck, Aleksander Pulver, Ruth Shimmo, Jaanus Harr. Active vs passive novelty-related strategies: Sex differences in exploratory behaviour and monoaminergic systems. Behavioural brain research. 2023-01-14. PMID:36641084. |
male rats had lower levels of dopamine (da) in frontal cortex, and higher levels of 3,4-dihydroxyphenylacetic acid (dopac) in raphe area; higher levels of serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) in dorsal striatum but lower levels of 5-ht and 5-hiaa in locus coeruleus area, 5-hiaa levels were also lower in hippocampus as compared to females. |
2023-01-14 |
2023-08-14 |
rat |
| . Expression of Concern: T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. PloS one. vol 18. issue 1. 2023-01-11. PMID:36630395. |
expression of concern: t-type calcium channel enhancer sak3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. |
2023-01-11 |
2023-08-14 |
mouse |
| P D Komleva, E Yu Bazhenova, N V Khotskin, E A Kulikova, A V Kuliko. C1473G Polymorphism in Tph2 Gene Affects Activation of Serotonin Metabolism in Mouse Brain 24 h after LPS Administration. Bulletin of experimental biology and medicine. 2023-01-04. PMID:36600037. |
we studied the effect of the c1473g polymorphism in the tph2 gene that reduces the activity of the tryptophan hydroxylase 2 in the brain on the severity of changes in motor activity (23 h after intraperitoneal administration of 0.8 mg/kg lps or saline) and on the level of serotonin (5-ht) and its metabolite 5-hydroxyindoleacetic acid (5-hiaa) in the endings of 5-ht neurons in the cortex, hippocampus, and striatum (24 h after administration) of mature male mice of congenic lines b6-1473cc (high activity) and b6-1473gg (low activity). |
2023-01-04 |
2023-08-14 |
mouse |
| Stefania Dimonte, Vladyslav Sikora, Maria Bove, Maria Grazia Morgese, Paolo Tucci, Stefania Schiavone, Luigia Trabac. Social isolation from early life induces anxiety-like behaviors in adult rats: Relation to neuroendocrine and neurochemical dysfunctions. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2023-01-02. PMID:36592494. |
no significant differences were found in noradrenaline and serotonin levels, as well as in serotonin turnover in hippocampus, while glutamate amount was increased and gaba levels were reduced in isolated rats. |
2023-01-02 |
2023-08-14 |
human |
| Parisa Ghanbari, Sanaz Khajehzadeh, Asieh Sayyed, Davood Raeisi, Omidreza Saleh. The effect of high intensity interval training with beetroot (Beta vulgaris) juice supplementation on serotonin and dopamine receptors expression, anxiety and depression in middle-aged diabetic rats. Avicenna journal of phytomedicine. vol 12. issue 6. 2022-12-30. PMID:36583177. |
the aim of this study was to evaluate the effect of four weeks of high intensity interval training (hiit) with beetroot juice supplementation (bj) on serotonin and dopamine receptors in hippocampal tissue, as well as anxiety and depression in middle-aged diabetic rats. |
2022-12-30 |
2023-08-14 |
rat |