| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rudy Schreiber, Adrian Newman-Tancred. Improving cognition in schizophrenia with antipsychotics that elicit neurogenesis through 5-HT(1A) receptor activation. Neurobiology of learning and memory. vol 110. 2014-12-03. PMID:24423786. |
mechanisms by which hippocampal adult neurogenesis can be increased are therefore of therapeutic interest and a promising molecular target is the activation of serotonin 5-ht(1a) receptors because agonists at this site increase adult neuronal proliferation in the dentate gyrus. |
2014-12-03 |
2023-08-12 |
Not clear |
| Rudy Schreiber, Adrian Newman-Tancred. Improving cognition in schizophrenia with antipsychotics that elicit neurogenesis through 5-HT(1A) receptor activation. Neurobiology of learning and memory. vol 110. 2014-12-03. PMID:24423786. |
recent antipsychotics, including clozapine and aripiprazole, exhibit different levels of 5-ht(1a) receptor partial agonism and may, therefore, differentially elicit hippocampal adult neurogenesis and increases in prefrontal cortex dopamine. |
2014-12-03 |
2023-08-12 |
Not clear |
| Man Tang, Tao He, Xiao Sun, Qing-Yan Meng, Yao Diao, Jie-Yu Lei, Xiao-Jing He, Lei Chen, Xiu-Bo Sang, Shulei Zha. Subregion-specific decreases in hippocampal serotonin transporter protein expression and function associated with endophenotypes of depression. Hippocampus. vol 24. issue 4. 2014-12-03. PMID:24436084. |
subregion-specific decreases in hippocampal serotonin transporter protein expression and function associated with endophenotypes of depression. |
2014-12-03 |
2023-08-12 |
mouse |
| Man Tang, Tao He, Xiao Sun, Qing-Yan Meng, Yao Diao, Jie-Yu Lei, Xiao-Jing He, Lei Chen, Xiu-Bo Sang, Shulei Zha. Subregion-specific decreases in hippocampal serotonin transporter protein expression and function associated with endophenotypes of depression. Hippocampus. vol 24. issue 4. 2014-12-03. PMID:24436084. |
the current study sought to determine whether chronic corticosteroid (cort) treatment influences serotonin transporter (5-htt) protein expression and function in the ca1, ca3, and dentate gyrus (dg) subregions of the hippocampus. |
2014-12-03 |
2023-08-12 |
mouse |
| Jamila Ahdidan, Leslie Foldager, Raben Rosenberg, Anders Rodell, Poul Videbech, Ole Mor. Hippocampal volume and serotonin transporter polymorphism in major depressive disorder. Acta neuropsychiatrica. vol 25. issue 4. 2014-12-02. PMID:25287633. |
hippocampal volume and serotonin transporter polymorphism in major depressive disorder. |
2014-12-02 |
2023-08-13 |
Not clear |
| Jamila Ahdidan, Leslie Foldager, Raben Rosenberg, Anders Rodell, Poul Videbech, Ole Mor. Hippocampal volume and serotonin transporter polymorphism in major depressive disorder. Acta neuropsychiatrica. vol 25. issue 4. 2014-12-02. PMID:25287633. |
the main aim of the present study was to replicate a previous finding in major depressive disorder (mdd) of association between reduced hippocampal volume and the long variant of the di- and triallelic serotonin transporter polymorphism in slc6a4 on chromosome 17q11.2. |
2014-12-02 |
2023-08-13 |
Not clear |
| Piotr Maciejak, Janusz Szyndler, Karolina Kołosowska, Danuta Turzyńska, Alicja Sobolewska, Jerzy Walkowiak, Adam Płaźni. Valproate disturbs the balance between branched and aromatic amino acids in rats. Neurotoxicity research. vol 25. issue 4. 2014-12-01. PMID:24249529. |
furthermore, we investigated whether the changes in the bcaa/aaa ratio affected the hippocampal concentration of monoamines [serotonin (5-ht), dopamine (da) and noradrenaline (na)]. |
2014-12-01 |
2023-08-12 |
rat |
| Piotr Maciejak, Janusz Szyndler, Karolina Kołosowska, Danuta Turzyńska, Alicja Sobolewska, Jerzy Walkowiak, Adam Płaźni. Valproate disturbs the balance between branched and aromatic amino acids in rats. Neurotoxicity research. vol 25. issue 4. 2014-12-01. PMID:24249529. |
the changes in the bcaa and aaa levels were accompanied by an increase in the na, da and 5-ht levels as well as hippocampal 5-ht metabolism. |
2014-12-01 |
2023-08-12 |
rat |
| Saloua Benmansour, Anthony A Privratsky, Opeyemi S Adeniji, Alan Fraze. Signaling mechanisms involved in the acute effects of estradiol on 5-HT clearance. The international journal of neuropsychopharmacology. vol 17. issue 5. 2014-12-01. PMID:24423185. |
the effect of local application of estradiol or selective agonists for erα (ppt) or erβ (dpn) into the ca3 region of the hippocampus of ovariectomized (ovx) rats on 5-hydroxytryptamine (5-ht) clearance as well as on the ability of fluvoxamine to slow 5-ht clearance was examined after selective blockade of signaling pathways or that of interacting receptors. |
2014-12-01 |
2023-08-12 |
rat |
| L Musazzi, J M Rimland, A Ieraci, G Racagni, E Domenici, M Popol. Pharmacological characterization of BDNF promoters I, II and IV reveals that serotonin and norepinephrine input is sufficient for transcription activation. The international journal of neuropsychopharmacology. vol 17. issue 5. 2014-12-01. PMID:24451568. |
we generated a gene reporter system based on hippocampal and cortical neuronal cultures, in which the transcription of luciferase is regulated by bdnf promoters i, ii, iv or by camp response element (cre), to investigate the activation of selected promoters induced by monoaminergic antidepressants and by serotonin or noradrenaline agonists. |
2014-12-01 |
2023-08-12 |
rat |
| Anshula Samarajeewa, Lolita Goldemann, Maryam S Vasefi, Nawaz Ahmed, Nyasha Gondora, Chandni Khanderia, John G Mielke, Michael A Beazel. 5-HT7 receptor activation promotes an increase in TrkB receptor expression and phosphorylation. Frontiers in behavioral neuroscience. vol 8. 2014-11-26. PMID:25426041. |
the serotonin (5-ht) type 7 receptor is expressed throughout the cns including the cortex and hippocampus. |
2014-11-26 |
2023-08-13 |
Not clear |
| Donatella Marazziti, Stefano Baroni, Lionella Palego, Laura Betti, Gino Giannaccini, Maura Castagna, Antonio G Naccarato, Antonio Luccachini, Mario Catena-Dell'Osso, Liliana Dell'Oss. Clozapine effects on adenylyl cyclase activity and serotonin type 1A receptors in human brain post-mortem. Journal of psychopharmacology (Oxford, England). vol 28. issue 4. 2014-11-24. PMID:24429224. |
the present work, therefore, aimed at evaluating the effects of clozapine and its major metabolite, norclozapine, on the modulation of adenylyl cyclase (ac) velocity via 5-ht(1a) receptors in human post-mortem brain regions, in particular the prefrontal cortex, hippocampus and raphe nuclei. |
2014-11-24 |
2023-08-12 |
human |
| Donatella Marazziti, Stefano Baroni, Lionella Palego, Laura Betti, Gino Giannaccini, Maura Castagna, Antonio G Naccarato, Antonio Luccachini, Mario Catena-Dell'Osso, Liliana Dell'Oss. Clozapine effects on adenylyl cyclase activity and serotonin type 1A receptors in human brain post-mortem. Journal of psychopharmacology (Oxford, England). vol 28. issue 4. 2014-11-24. PMID:24429224. |
the receptor characterisation of the clozapine effect on ac observed in the hippocampus by the use of antagonists showed a mixed profile, involving not only the 5-ht(1a) receptor but also a muscarinic (m) receptor subtype, most likely the m₄ one. |
2014-11-24 |
2023-08-12 |
human |
| Shimako Yoshitake, Eugenia Kuteeva, Tomas Hökfelt, Françoise Mennicken, Elvar Theodorsson, Masatoshi Yamaguchi, Jan Kehr, Takashi Yoshitak. Correlation between the effects of local and intracerebroventricular infusions of galanin on 5-HT release studied by microdialysis, and distribution of galanin and galanin receptors in prefrontal cortex, ventral hippocampus, amygdala, hypothalamus, and striatum of awake rats. Synapse (New York, N.Y.). vol 68. issue 5. 2014-11-07. PMID:24430888. |
correlation between the effects of local and intracerebroventricular infusions of galanin on 5-ht release studied by microdialysis, and distribution of galanin and galanin receptors in prefrontal cortex, ventral hippocampus, amygdala, hypothalamus, and striatum of awake rats. |
2014-11-07 |
2023-08-12 |
rat |
| Shimako Yoshitake, Eugenia Kuteeva, Tomas Hökfelt, Françoise Mennicken, Elvar Theodorsson, Masatoshi Yamaguchi, Jan Kehr, Takashi Yoshitak. Correlation between the effects of local and intracerebroventricular infusions of galanin on 5-HT release studied by microdialysis, and distribution of galanin and galanin receptors in prefrontal cortex, ventral hippocampus, amygdala, hypothalamus, and striatum of awake rats. Synapse (New York, N.Y.). vol 68. issue 5. 2014-11-07. PMID:24430888. |
infusions of galanin on basal extracellular 5-ht levels in medial prefrontal cortex (mpfc), ca1 area of ventral hippocampus (vhpc), central amygdaloid nucleus (cea), ventromedial hypothalamic nucleus ventrolateral part (vmhvl), and ventromedial caudate putamen (cpu). |
2014-11-07 |
2023-08-12 |
rat |
| Samina Bano, Iffat Ara, Kausar Saboohi, Tariq Moattar, Bushra Chaoudhr. St. John's Wort increases brain serotonin synthesis by inhibiting hepatic tryptophan 2, 3 dioxygenase activity and its gene expression in stressed rats. Pakistan journal of pharmaceutical sciences. vol 27. issue 5 Spec no. 2014-11-07. PMID:25176236. |
the drug also decreases serotonin turnover in all the brain areas (hypothalamus, hippocampus amygdala) in stressed rats endorsing its monoamine oxidase inhibition property. |
2014-11-07 |
2023-08-13 |
rat |
| Mizuho Takahashi, Ayako Yamanaka, Chihiro Asanuma, Hiroko Asano, Tadaaki Satou, Kazuo Koik. Anxiolytic-like effect of inhalation of essential oil from Lavandula officinalis: investigation of changes in 5-HT turnover and involvement of olfactory stimulation. Natural product communications. vol 9. issue 7. 2014-10-30. PMID:25230519. |
lveo significantly increased the striatal and hippocampal levels of 5-ht and decreased turnover rates in accordance with the anxiolytic behavioral changes. |
2014-10-30 |
2023-08-13 |
mouse |
| N Yu Glazova, S A Merchieva, M A Volodina, E A Sebentsova, D M Manchenko, V S Kudrun, N G Levitskay. Effects of neonatal fluvoxamine administration on the physical development and activity of the serotoninergic system in white rats. Acta naturae. vol 6. issue 3. 2014-10-28. PMID:25349718. |
furthermore, increased noradrenalin level in hypothalamus, serotonin level in hippocampus and serotonin metabolite 5-hiaa level in frontal cortex, hypothalamus, hippocampus, and striatum were observed in drug-treated animals compared to the control group. |
2014-10-28 |
2023-08-13 |
human |
| Eman S H Abd Allah, Asmaa M S Gomaa, Manal M Saye. The effect of omega-3 on cognition in hypothyroid adult male rats. Acta physiologica Hungarica. vol 101. issue 3. 2014-10-24. PMID:25183510. |
serum total antioxidant capacity (tac) and hippocampal serotonin and γ-aminobutyric acid (gaba) levels were decreased in the hypothyroid group as compared to the control group. |
2014-10-24 |
2023-08-13 |
rat |
| C Brad Wilson, Philip J Ebenezer, Leslie D McLaughlin, Joseph Franci. Predator exposure/psychosocial stress animal model of post-traumatic stress disorder modulates neurotransmitters in the rat hippocampus and prefrontal cortex. PloS one. vol 9. issue 2. 2014-10-21. PMID:24551226. |
in this study, we hypothesized the predator exposure/psychosocial stress rodent model of ptsd may alter levels of 5-ht and other neurotransmitters in the rat hippocampus and prefrontal cortex (pfc). |
2014-10-21 |
2023-08-12 |
human |