| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Brad Wilson, Philip J Ebenezer, Leslie D McLaughlin, Joseph Franci. Predator exposure/psychosocial stress animal model of post-traumatic stress disorder modulates neurotransmitters in the rat hippocampus and prefrontal cortex. PloS one. vol 9. issue 2. 2014-10-21. PMID:24551226. |
norepinephrine (ne), 5-hydroxyindoleacetic acid (5-hiaa), homovanillic acid (hva), dopamine (da), and 3,4-dihydroxyphenylacetic acid (dopac), and 5-ht levels in the hippocampus and pfc were measured with high-performance liquid chromatography (hplc). |
2014-10-21 |
2023-08-12 |
human |
| C Brad Wilson, Philip J Ebenezer, Leslie D McLaughlin, Joseph Franci. Predator exposure/psychosocial stress animal model of post-traumatic stress disorder modulates neurotransmitters in the rat hippocampus and prefrontal cortex. PloS one. vol 9. issue 2. 2014-10-21. PMID:24551226. |
in the hippocampus, 5-ht and hva were lower, while ne and dopac were higher, in the ptsd group vs. controls. |
2014-10-21 |
2023-08-12 |
human |
| Ken-Ichi Ohta, Takanori Miki, Katsuhiko Warita, Shingo Suzuki, Takashi Kusaka, Tomiko Yakura, Jun-Qian Liu, Motoki Tamai, Yoshiki Takeuch. Prolonged maternal separation disturbs the serotonergic system during early brain development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 33. 2014-10-10. PMID:24184298. |
hplc revealed imbalance between serotonin and 5-hydroxyindoleacetic acid in midbrain raphe nuclei, the amygdala, the hippocampus, and the medial prefrontal cortex (mpfc) on pds 7 and 14. |
2014-10-10 |
2023-08-12 |
rat |
| Ken-Ichi Ohta, Takanori Miki, Katsuhiko Warita, Shingo Suzuki, Takashi Kusaka, Tomiko Yakura, Jun-Qian Liu, Motoki Tamai, Yoshiki Takeuch. Prolonged maternal separation disturbs the serotonergic system during early brain development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 33. 2014-10-10. PMID:24184298. |
furthermore, real-time rt-pcr showed attenuation of mrna expression of the serotonin 1a receptor in the hippocampus and the mpfc and of the serotonin 2a receptor only in the mpfc on pds 7 and 14. |
2014-10-10 |
2023-08-12 |
rat |
| Benjamin D Sachs, Jason R Ni, Marc G Caro. Sex differences in response to chronic mild stress and congenital serotonin deficiency. Psychoneuroendocrinology. vol 40. 2014-10-09. PMID:24485484. |
although cms did not reduce cell proliferation in the hippocampus, low levels of brain 5-ht were associated with increased hippocampal cell proliferation, an effect that was predominantly observed in females. |
2014-10-09 |
2023-08-12 |
mouse |
| Karita Raudkivi, Tanel Mällo, Jaanus Harr. Effect of chronic variable stress on corticosterone levels and hippocampal extracellular 5-HT in rats with persistent differences in positive affectivity. Acta neuropsychiatrica. vol 24. issue 4. 2014-10-08. PMID:25286813. |
effect of chronic variable stress on corticosterone levels and hippocampal extracellular 5-ht in rats with persistent differences in positive affectivity. |
2014-10-08 |
2023-08-13 |
rat |
| Yun-Fang Jia, Ning-Ning Song, Rong-Rong Mao, Jin-Nan Li, Qiong Zhang, Ying Huang, Lei Zhang, Hui-Li Han, Yu-Qiang Ding, Lin X. Abnormal anxiety- and depression-like behaviors in mice lacking both central serotonergic neurons and pancreatic islet cells. Frontiers in behavioral neuroscience. vol 8. 2014-10-08. PMID:25294992. |
these results suggest that the deficiency of central 5-ht may not be sufficient to induce anxiety/depression-like behaviors in mice, and the enhanced hippocampal neurogenesis may contribute to the altered depression-like behaviors in the 5-ht-deficient mice with diabetes. |
2014-10-08 |
2023-08-13 |
mouse |
| Mai A Abd-El-Fattah, Noha F Abdelakader, Hala F Zak. Pyrrolidine dithiocarbamate protects against scopolamine-induced cognitive impairment in rats. European journal of pharmacology. vol 723. 2014-10-07. PMID:24315930. |
rats were then sacrificed and homogenates of cortical and hippocampal tissues were used for the estimation of noradrenaline, dopamine, serotonin and heat shock protein 70 contents along with acetylcholinesterase activity. |
2014-10-07 |
2023-08-12 |
rat |
| Li-Ping Guan, Li-Ming Tang, Cheng-Yan Pan, Shui-Lian Zhao, Si-Hong Wan. Evaluation of potential antidepressant-like activity of chalcone-1203 in various murine experimental depressant models. Neurochemical research. vol 39. issue 2. 2014-10-07. PMID:24343532. |
it was found that chalcone-1203 significantly increased the concentrations of the main neurotransmitters 5-ht and ne in the hippocampus, hypothalamus and cortex. |
2014-10-07 |
2023-08-12 |
mouse |
| Li-Ping Guan, Li-Ming Tang, Cheng-Yan Pan, Shui-Lian Zhao, Si-Hong Wan. Evaluation of potential antidepressant-like activity of chalcone-1203 in various murine experimental depressant models. Neurochemical research. vol 39. issue 2. 2014-10-07. PMID:24343532. |
chalcone-1203 also significantly reduced the ratio of 5-hiaa/5-ht in the hippocampus and cortex, shown down 5-ht metabolism compared with mice treated with stress vehicle. |
2014-10-07 |
2023-08-12 |
mouse |
| Li-Ping Guan, Li-Ming Tang, Cheng-Yan Pan, Shui-Lian Zhao, Si-Hong Wan. Evaluation of potential antidepressant-like activity of chalcone-1203 in various murine experimental depressant models. Neurochemical research. vol 39. issue 2. 2014-10-07. PMID:24343532. |
in conclusion, chalcone-1203 produced significant antidepressant-like activity, and the mechanism of action may be due to increased 5-ht and ne in the mouse hippocampus and cortex. |
2014-10-07 |
2023-08-12 |
mouse |
| Sumitaka Inoue, Hiroki Shikanai, Machiko Matsumoto, Sachiko Hiraide, Yasuhiro Saito, Yoshiki Yanagawa, Mitsuhiro Yoshioka, Kei-ichi Shimamura, Hiroko Togash. Metaplastic regulation of the median raphe nucleus via serotonin 5-HT1A receptor on hippocampal synaptic plasticity is associated with gender-specific emotional expression in rats. Journal of pharmacological sciences. vol 124. issue 3. 2014-09-30. PMID:24599137. |
metaplastic regulation of the median raphe nucleus via serotonin 5-ht1a receptor on hippocampal synaptic plasticity is associated with gender-specific emotional expression in rats. |
2014-09-30 |
2023-08-12 |
rat |
| Sumitaka Inoue, Hiroki Shikanai, Machiko Matsumoto, Sachiko Hiraide, Yasuhiro Saito, Yoshiki Yanagawa, Mitsuhiro Yoshioka, Kei-ichi Shimamura, Hiroko Togash. Metaplastic regulation of the median raphe nucleus via serotonin 5-HT1A receptor on hippocampal synaptic plasticity is associated with gender-specific emotional expression in rats. Journal of pharmacological sciences. vol 124. issue 3. 2014-09-30. PMID:24599137. |
extracellular 5-ht levels in the hippocampus were increased by cfc only in the males. |
2014-09-30 |
2023-08-12 |
rat |
| Raphaelle Mottolese, Jérôme Redouté, Nicolas Costes, Didier Le Bars, Angela Sirig. Switching brain serotonin with oxytocin. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 23. 2014-09-30. PMID:24912179. |
importantly, the amygdala appears central in the regulation of 5-ht by oxt: [(18)f]mppf bpnd changes in the drn correlated with changes in right amygdala, which were in turn correlated with changes in hippocampus, insula, subgenual, and orbitofrontal cortex, a circuit implicated in the control of stress, mood, and social behaviors. |
2014-09-30 |
2023-08-13 |
human |
| Zlatina Petkova, Jana Tchekalarova, Daniela Pechlivanova, Slavianka Moyanova, Lidia Kortenska, Rumiana Mitreva, Deyan Popov, Petya Markova, Valentin Lozanov, Dimitrina Atanasova, Nikolai Lazarov, Alexander Stoyne. Treatment with melatonin after status epilepticus attenuates seizure activity and neuronal damage but does not prevent the disturbance in diurnal rhythms and behavioral alterations in spontaneously hypertensive rats in kainate model of temporal lobe epilepsy. Epilepsy & behavior : E&B. vol 31. 2014-09-29. PMID:24440891. |
melatonin reduced neuronal damage specifically in the ca1 area of the hippocampus and piriform cortex and decreased hippocampal serotonin (5-ht) levels both in control and epileptic shrs. |
2014-09-29 |
2023-08-12 |
rat |
| Xuan Liu, Junjian Zhang, Dong Sun, Yuanteng Fan, Hongbin Zhou, Binfang F. Effects of fluoxetine on brain-derived neurotrophic factor serum concentration and cognition in patients with vascular dementia. Clinical interventions in aging. vol 9. 2014-09-29. PMID:24648723. |
selective serotonin reuptake inhibitors improve cognition in patients with stroke and increase the expression of brain-derived neurotrophic factor (bdnf) in the rat hippocampus. |
2014-09-29 |
2023-08-12 |
rat |
| Aline Isabel da Silva, Ligia Cristina Monteiro Galindo, Luciana Nascimento, Cristiane Moura Freitas, Raul Manhaes-de-Castro, Claudia Jacques Lagranha, Sandra Lopes de Souz. Fluoxetine treatment of rat neonates significantly reduces oxidative stress in the hippocampus and in behavioral indicators of anxiety later in postnatal life. Canadian journal of physiology and pharmacology. vol 92. issue 4. 2014-09-26. PMID:24708216. |
the aim of this study was to evaluate the effect of fluoxetine-inhibited serotonin reuptake in nursing rat neonates on behavior and on oxidative stress in the hypothalamus and the hippocampus; brain areas responsible for behavior related to food and anxiety, respectively. |
2014-09-26 |
2023-08-13 |
rat |
| Hyun Jung Kim, Seungwoo Kang, Hyun Ju Kim, Sun-Hye Choi, Seungkeun Shin, Hyung Ha Lee, Hyewhon Rhim, Kyung Ho Shi. Effect of acute and chronic electroconvulsive shock on 5-hydroxytrypamine 6 receptor immunoreactivity in rat hippocampus. Experimental neurobiology. vol 23. issue 3. 2014-09-26. PMID:25258570. |
one potential mechanism underlying both the antidepressant and amnesia effect of ecs may involve the regulation of serotonin (5-hydroxytryptamine) 6 (5-ht6) receptor, but less is known about the effects of acute ecs on the changes in 5-ht6 receptor expression in the hippocampus. |
2014-09-26 |
2023-08-13 |
rat |
| Georg S Kranz, Andreas Hahn, Pia Baldinger, Daniela Haeusler, Cecile Philippe, Ulrike Kaufmann, Wolfgang Wadsak, Markus Savli, Anna Hoeflich, Christoph Kraus, Thomas Vanicek, Markus Mitterhauser, Siegfried Kasper, Rupert Lanzenberge. Cerebral serotonin transporter asymmetry in females, males and male-to-female transsexuals measured by PET in vivo. Brain structure & function. vol 219. issue 1. 2014-09-19. PMID:23224294. |
voxel-wise analysis of serotonin transporter binding in all groups showed both strong left and rightward asymmetries in several cortical and subcortical structures including temporal and frontal cortices, anterior cingulate, hippocampus, caudate and thalamus. |
2014-09-19 |
2023-08-12 |
Not clear |
| Sadia Saleem, Saiqa Tabassum, Sana Ahmed, Tahira Perveen, Saida Haide. Senescence related alteration in hippocampal biogenic amines produces neuropsychological deficits in rats. Pakistan journal of pharmaceutical sciences. vol 27. issue 4. 2014-09-18. PMID:25015449. |
the major goal of the present study was to investigate the age associated cognitive dysfunction and other behavioral changes and their association with age related alterations in levels of neurotransmitters, such as dopamine (da) and serotonin (5-ht) in the hippocampal region. |
2014-09-18 |
2023-08-13 |
rat |