All Relations between hippocampus and serotonin

Reference Sentence Publish Date Extraction Date Species
P Van den Hooff, M Galva. Electrophysiology of the 5-HT1A ligand MDL 73005EF in the rat hippocampal slice. European journal of pharmacology vol 196 issue 3 1991 1893914 the actions of 5-hydroxytryptamine (5-ht) and the 5-ht1a receptor ligand mdl 73005ef on neuronal activity in the ca1 region of rat hippocampal slices in vitro were recorded using intra- and extracellular recording techniques. 1991-10-24 2022-01-10 Not clear
M E Newman, A Ben-Zeev, B Lere. Chloroamphetamine did not prevent the effects of chronic antidepressants on 5-hydroxytryptamine inhibition of forskolin-stimulated adenylate cyclase in rat hippocampus. European journal of pharmacology vol 207 issue 3 1991 1654266 on two occasions) to rats resulted in a severe depletion of [3h]paroxetine binding sites, a measure of presynaptic serotonergic terminals, in both cortex and hippocampus, but did not affect [3h]8-hydroxy-2-(di-n-propylamino)tetralin [( 3h]8-oh-dpat) binding or 5-hydroxytryptamine (5-ht)-induced inhibition of forskolin-stimulated adenylate cyclase in hippocampal membranes. 1991-10-22 2022-01-10 Not clear
M E Newman, A Ben-Zeev, B Lere. Chloroamphetamine did not prevent the effects of chronic antidepressants on 5-hydroxytryptamine inhibition of forskolin-stimulated adenylate cyclase in rat hippocampus. European journal of pharmacology vol 207 issue 3 1991 1654266 for 2 weeks) or lithium (0.2% for 2 weeks) to pca-treated rats did not affect [3h]8-oh-dpat binding but reduced the degree of inhibition of forskolin-stimulated adenylate cyclase by 5-ht in hippocampal membranes. 1991-10-22 2022-01-10 Not clear
R Alonso, P Soubri. Effects of serotonergic denervation on the density and plasticity of brain muscarinic receptors in the rat. Synapse (New York, N.Y.) vol 8 issue 1 1991 1714634 intracerebroventricular injection of 5,7-dihydroxytryptamine (5,7-dht) in rats produced a 90% reduction in cortical and hippocampal 5-hydroxytryptamine (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) contents. 1991-09-16 2022-01-10 Not clear
R Alonso, P Soubri. Effects of serotonergic denervation on the density and plasticity of brain muscarinic receptors in the rat. Synapse (New York, N.Y.) vol 8 issue 1 1991 1714634 these results suggest 1) that 5-ht denervation did not affect the density and sensitivity of muscarinic receptors and 2) that the ability of cortical and hippocampal non-m1 receptors to up-regulate following repeated injection of scopolamine requires the integrity of 5-ht neurons terminating in these brain structures. 1991-09-16 2022-01-10 Not clear
I Kusumi, M Mikuni, K Takahash. Effect of subchronic antidepressants administration on serotonin-stimulated phosphoinositide hydrolysis in para-chlorophenylalanine-treated rat hippocampal slices. Progress in neuro-psychopharmacology & biological psychiatry vol 15 issue 3 1991 1713698 this study examines the effect of subchronic parachlorophenylalanine (pcpa) treatment upon serotonin (5-ht)-stimulated inositol monophosphate (ip-1) accumulation in rat hippocampal slices and also the effect of antidepressants upon this 5-ht response in the hippocampus from rats treated with or without concurrent administration of pcpa. 1991-08-30 2022-01-10 Not clear
M Gobbi, S Cavanus, A Miari, T Mennin. Effect of acute and chronic administration of buspirone on serotonin and benzodiazepine receptor subtypes in the rat brain: an autoradiographic study. Neuropharmacology vol 30 issue 4 1991 1649418 the results confirmed that buspirone is a selective 5-ht1a ligand, since it inhibited the binding of [3h]5-ht with lower ic50 values (about 100 nm) in regions of the brain of the rat where this receptor subtype is predominant (such as hippocampal areas). 1991-08-20 2022-01-10 Not clear
C Sotel. Immunohistochemical study of short- and long-term effects of DL-fenfluramine on the serotonergic innervation of the rat hippocampal formation. Brain research vol 541 issue 2 1991 2054644 owing to the long-lasting depletion in brain serotonin (5-ht) produced by high doses of the amphetamine derivative dl-fenfluramine, this drug has been suspected of neurotoxicity; the serotonergic innervation of the hippocampal formation being one of its most vulnerable targets. 1991-08-01 2022-01-10 Not clear
C Sotel. Immunohistochemical study of short- and long-term effects of DL-fenfluramine on the serotonergic innervation of the rat hippocampal formation. Brain research vol 541 issue 2 1991 2054644 in parallel with this decrease, numerous 5-ht-ir fibers in the cingulum bundle, fornix-fimbria and the hippocampal parenchyma exhibit structural changes, similar to those produced by 5,7-dihydroxytryptamine, a specific neurotoxin of the 5-ht system. 1991-08-01 2022-01-10 Not clear
C Sotel. Immunohistochemical study of short- and long-term effects of DL-fenfluramine on the serotonergic innervation of the rat hippocampal formation. Brain research vol 541 issue 2 1991 2054644 by 40 days, the pattern of 5-ht hippocampal innervation is restored but its density is still lower than in controls. 1991-08-01 2022-01-10 Not clear
P S Whitton, G S Sarna, M T O'Connell, G Curzo. The effect of the novel antidepressant tianeptine on the concentration of 5-hydroxytryptamine in rat hippocampal dialysates in vivo. Neuropharmacology vol 30 issue 1 1991 2046875 the effect of the novel antidepressant tianeptine on the concentration of 5-hydroxytryptamine in rat hippocampal dialysates in vivo. 1991-07-17 2022-01-10 Not clear
P S Whitton, G S Sarna, M T O'Connell, G Curzo. The effect of the novel antidepressant tianeptine on the concentration of 5-hydroxytryptamine in rat hippocampal dialysates in vivo. Neuropharmacology vol 30 issue 1 1991 2046875 ), given acutely, did not reduce basal levels of 5-ht in hippocampal dialysates in the presence of the 5-ht reuptake inhibitor, citalopram. 1991-07-17 2022-01-10 Not clear
R Andrade, Y Chapu. 5-Hydroxytryptamine4-like receptors mediate the slow excitatory response to serotonin in the rat hippocampus. The Journal of pharmacology and experimental therapeutics vol 257 issue 3 1991 2046027 hippocampal pyramidal neurons of the ca1 region express 5-hydroxytryptamine (serotonin, 5-ht) receptors which, upon activation, elicit a slow membrane depolarization and a decrease in the calcium-activated afterhyperpolarization present in these cells. 1991-07-12 2022-01-10 Not clear
T Alexi, E C Azmiti. Ethanol stimulates [3H]5-HT high-affinity uptake by rat forebrain synaptosomes: role of 5-HT receptors and voltage channel blockers. Brain research vol 544 issue 2 1991 1645610 we report that a dose of ethanol which causes general anesthesia in humans (54 mm) applied in vitro enhanced rat synaptosomal [3h]5-ht uptake after 5 min at 37 degrees c. similar levels of stimulation by 54 mm ethanol were seen in hippocampal, cerebral cortex and brainstem synaptosomes. 1991-07-11 2022-01-10 Not clear
M P Johnson, X M Huang, R Oberlender, J F Nash, D E Nichol. Behavioral, biochemical and neurotoxicological actions of the alpha-ethyl homologue of p-chloroamphetamine. European journal of pharmacology vol 191 issue 1 1991 1982656 a 10 mg/kg dose of pca caused an 80% decrease in cortical and hippocampal serotonergic markers, while an equimolar dose of cab decreased only hippocampal 5-ht and 5-hydroxyindoleacetic acid (5-hiaa) levels. 1991-06-17 2022-01-10 Not clear
A Varrault, V Leviel, J Bockaer. 5-HT1A-sensitive adenylyl cyclase of rodent hippocampal neurons: effects of antidepressant treatments and chronic stimulation with agonists. The Journal of pharmacology and experimental therapeutics vol 257 issue 1 1991 2020001 the effects of chronic treatment with desimipramine (a tricyclic antidepressant), fluoxetine [a specific 5-hydroxytryptamine (5-ht) uptake inhibitor], clorgyline (a specific monoamine oxydase inhibitor of a type), ipsapirone (a specific 5-ht1a receptor agonist) as well as electroconvulsive shock treatment were investigated on rat hippocampal 5-ht1a receptors negatively coupled to adenylyl cyclase. 1991-05-24 2022-01-10 Not clear
A Varrault, V Leviel, J Bockaer. 5-HT1A-sensitive adenylyl cyclase of rodent hippocampal neurons: effects of antidepressant treatments and chronic stimulation with agonists. The Journal of pharmacology and experimental therapeutics vol 257 issue 1 1991 2020001 in contrast, chronic treatment with clorgyline and electroconvulsive shock treatment induced a slight but significant reduction of 5-ht's ability to inhibit hippocampal adenylyl cyclase. 1991-05-24 2022-01-10 Not clear
A Varrault, V Leviel, J Bockaer. 5-HT1A-sensitive adenylyl cyclase of rodent hippocampal neurons: effects of antidepressant treatments and chronic stimulation with agonists. The Journal of pharmacology and experimental therapeutics vol 257 issue 1 1991 2020001 this was verified in vitro on murine hippocampal neurons in culture, by measuring the effects of intense stimulation (1 and 2 hours), with 5-ht, ipsapirone and 8-hydroxy-2-(di-n-propylamino)tetralin. 1991-05-24 2022-01-10 Not clear
S E Gartside, P J Cowen, S Hjort. Effects of MDL 73005EF on central pre- and postsynaptic 5-HT1A receptor function in the rat in vivo. European journal of pharmacology vol 191 issue 3 1991 1964908 mdl 73005ef dose dependently decreased the hippocampal 5-ht output measured by in vivo microdialysis in chloral hydrate-anaesthetised rats and this response was antagonised by the 5-ht1a/b receptor antagonist, pindolol. 1991-05-23 2022-01-10 Not clear
S E Gartside, P J Cowen, S Hjort. Effects of MDL 73005EF on central pre- and postsynaptic 5-HT1A receptor function in the rat in vivo. European journal of pharmacology vol 191 issue 3 1991 1964908 local administration of mdl 73005ef had no effect on the hippocampal 5-ht output. 1991-05-23 2022-01-10 Not clear
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