| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takeshi Inoue, Yuji Kitaichi, Tsukasa Koyam. SSRIs and conditioned fear. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 8. 2014-06-09. PMID:21925230. |
microinjection studies revealed the amygdala as the target brain region of both classes of serotonergic drugs, and the hippocampus as the target of 5-ht(1a) receptor agonists. |
2014-06-09 |
2023-08-12 |
Not clear |
| Frances A Champagn. Early environments, glucocorticoid receptors, and behavioral epigenetics. Behavioral neuroscience. vol 127. issue 5. 2014-06-06. PMID:24128352. |
changes in hippocampal gr induced by handling were determined to be the outcome of a cascade of cellular and molecular events involving thyroid hormones, serotonin turnover, and transcription factor binding to the nr3c1 gene, leading to increased gr mrna and protein. |
2014-06-06 |
2023-08-12 |
rat |
| Masatoshi Yamashita, Takanobu Yamamot. Tryptophan and kynurenic Acid may produce an amplified effect in central fatigue induced by chronic sleep disorder. International journal of tryptophan research : IJTR. vol 7. 2014-06-06. PMID:24899814. |
results showed that while 5-hydroxytryptamine (5-ht) concentration did not differ between control and cfsd groups, levels of trp and kyna in the cfsd group were about 2 and 5 times higher in the hypothalamus, and 2 and 3.5 times higher in the hippocampus, respectively. |
2014-06-06 |
2023-08-13 |
rat |
| B D Sachs, J P R Jacobsen, T L Thomas, W B Siesser, W L Roberts, M G Caro. The effects of congenital brain serotonin deficiency on responses to chronic fluoxetine. Translational psychiatry. vol 3. 2014-06-05. PMID:23942622. |
the importance of reversing brain serotonin (5-ht) deficiency and promoting hippocampal neurogenesis in the mechanisms of action for antidepressants remain highly controversial. |
2014-06-05 |
2023-08-12 |
mouse |
| Mariana B Proença, Patrícia A Dombrowski, Claudio Da Cunha, Luana Fischer, Anete C Ferraz, Marcelo M S Lim. Dopaminergic D2 receptor is a key player in the substantia nigra pars compacta neuronal activation mediated by REM sleep deprivation. Neuropharmacology. vol 76 Pt A. 2014-06-05. PMID:24012539. |
accordingly, we performed striatal and hippocampal neurochemical quantifications of da, serotonin (5-ht) and metabolites of rats intraperitoneally treated with haloperidol (1.5 mg/kg) or piribedil (8 mg/kg) and submitted to rem sleep deprivation (remsd) and sleep rebound (reb). |
2014-06-05 |
2023-08-12 |
rat |
| Adele Stewart, Biswanath Maity, Amanda M Wunsch, Fantao Meng, Qi Wu, John A Wemmie, Rory A Fishe. Regulator of G-protein signaling 6 (RGS6) promotes anxiety and depression by attenuating serotonin-mediated activation of the 5-HT(1A) receptor-adenylyl cyclase axis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 28. issue 4. 2014-06-02. PMID:24421401. |
rgs6 is enriched in hippocampal and cortical neurons, 5-ht(1a)r-expressing cells implicated in mood disorders. |
2014-06-02 |
2023-08-12 |
mouse |
| H A Gromova, A R Chubakov, E I Chumasov, H V Konovalo. Serotonin as a stimulator of hippocampal cell differentiation in tissue culture. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 1. issue 6. 2014-06-02. PMID:24873688. |
serotonin as a stimulator of hippocampal cell differentiation in tissue culture. |
2014-06-02 |
2023-08-13 |
rat |
| H A Gromova, A R Chubakov, E I Chumasov, H V Konovalo. Serotonin as a stimulator of hippocampal cell differentiation in tissue culture. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 1. issue 6. 2014-06-02. PMID:24873688. |
the effects of serotonin (5-ht) on morphofunctional development of hippocampal cultures derived from newborn rats were studied. |
2014-06-02 |
2023-08-13 |
rat |
| H A Gromova, A R Chubakov, E I Chumasov, H V Konovalo. Serotonin as a stimulator of hippocampal cell differentiation in tissue culture. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 1. issue 6. 2014-06-02. PMID:24873688. |
electrophysiological studies of hippocampal cells in 5-ht treated cultures showed earlier exhibition of spontaneous activity and an increased number of spontaneously firing neurons and prevalence of periodic (bursting) type of discharges. |
2014-06-02 |
2023-08-13 |
rat |
| H A Gromova, A R Chubakov, E I Chumasov, H V Konovalo. Serotonin as a stimulator of hippocampal cell differentiation in tissue culture. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 1. issue 6. 2014-06-02. PMID:24873688. |
these results indicate that 5-ht stimulates the differentiation of hippocampal cells in tissue culture. |
2014-06-02 |
2023-08-13 |
rat |
| Yingcong Yu, Rui Wang, Chunbai Chen, Xia Du, Lina Ruan, Jiao Sun, Jianxin Li, Lu Zhang, James M O'Donnell, Jianchun Pan, Ying X. Antidepressant-like effect of trans-resveratrol in chronic stress model: behavioral and neurochemical evidences. Journal of psychiatric research. vol 47. issue 3. 2014-05-30. PMID:23174668. |
the neurochemical assay showed that higher dose of trans-resveratrol (80 mg/kg) produced a marked increase of 5-ht levels in three brain regions, the frontal cortex, hippocampus and hypothalamus. |
2014-05-30 |
2023-08-12 |
rat |
| Christian Webhofer, Philipp Gormanns, Stefan Reckow, Maria Lebar, Giuseppina Maccarrone, Tonia Ludwig, Benno Pütz, John M Asara, Florian Holsboer, Inge Sillaber, Walter Zieglgänsberger, Christoph W Turc. Proteomic and metabolomic profiling reveals time-dependent changes in hippocampal metabolism upon paroxetine treatment and biomarker candidates. Journal of psychiatric research. vol 47. issue 3. 2014-05-30. PMID:23207114. |
in the present study we aimed at identifying hippocampal cellular pathway alterations in dba/2 mice using paroxetine as a representative selective serotonin reuptake inhibitor (ssri). |
2014-05-30 |
2023-08-12 |
mouse |
| S Migliarini, G Pacini, B Pelosi, G Lunardi, M Pasqualett. Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:23007167. |
finally, we demonstrated that bdnf expression is significantly up-regulated in the hippocampus of mice lacking brain 5-ht, mirroring the timing of the appearance of hyperinnervation and thus unmasking a possible regulatory feedback mechanism tuning the serotonergic neuronal circuitry formation. |
2014-05-29 |
2023-08-12 |
mouse |
| T M Eriksson, A Alvarsson, T L Stan, X Zhang, K N Hascup, E R Hascup, J Kehr, G A Gerhardt, J Warner-Schmidt, M Arango-Lievano, M G Kaplitt, S O Ogren, P Greengard, P Svenningsso. Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:23032875. |
unexpectedly, 5-ht(1b)r agonist stimulation enhanced memory in p11ko mice, and this atypical switch was reversed after hippocampal adeno-associated virus mediated gene transfer of p11. |
2014-05-29 |
2023-08-12 |
mouse |
| T M Eriksson, A Alvarsson, T L Stan, X Zhang, K N Hascup, E R Hascup, J Kehr, G A Gerhardt, J Warner-Schmidt, M Arango-Lievano, M G Kaplitt, S O Ogren, P Greengard, P Svenningsso. Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:23032875. |
notably, 5-ht(1b)r stimulation increased glutamatergic neurotransmission in the hippocampus in p11ko mice, but not in wt mice, as measured by both pre- and postsynaptic criteria. |
2014-05-29 |
2023-08-12 |
mouse |
| T M Eriksson, A Alvarsson, T L Stan, X Zhang, K N Hascup, E R Hascup, J Kehr, G A Gerhardt, J Warner-Schmidt, M Arango-Lievano, M G Kaplitt, S O Ogren, P Greengard, P Svenningsso. Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:23032875. |
magnetic resonance spectroscopy demonstrated global hippocampal reductions of inhibitory gaba, which may contribute to the memory enhancement and potentiation of pre- and post-synaptic measures of glutamate transmission by a 5-ht(1b)r agonist in p11ko mice. |
2014-05-29 |
2023-08-12 |
mouse |
| T M Eriksson, A Alvarsson, T L Stan, X Zhang, K N Hascup, E R Hascup, J Kehr, G A Gerhardt, J Warner-Schmidt, M Arango-Lievano, M G Kaplitt, S O Ogren, P Greengard, P Svenningsso. Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:23032875. |
it is concluded that the level of hippocampal p11 determines the directionality of 5-ht(1b)r action on emotional memory processing and modulates hippocampal functionality. |
2014-05-29 |
2023-08-12 |
mouse |
| Mette Ewers Haahr, Patrick Fisher, Klaus Holst, Karine Madsen, Christian Gaden Jensen, Lisbeth Marner, Szabols Lehel, William Baaré, Gitte Knudsen, Steen Hasselbalc. The 5-HT4 receptor levels in hippocampus correlates inversely with memory test performance in humans. Human brain mapping. vol 34. issue 11. 2014-05-28. PMID:22736538. |
the cerebral serotonin (5-ht) system is involved in cognitive functions such as memory and learning and animal studies have repeatedly shown that stimulation of the 5-ht type 4 receptor (5-ht4 r) facilitates memory and learning and further that the 5-ht4 r modulates cellular memory processes in hippocampus. |
2014-05-28 |
2023-08-12 |
human |
| Gergely Orban, Massimo Pierucci, Arcangelo Benigno, Mauro Pessia, Salvatore Galati, Mario Valentino, Richard Muscat, Giuseppe Di Giovann. High dose of 8-OH-DPAT decreases maximal dentate gyrus activation and facilitates granular cell plasticity in vivo. Experimental brain research. vol 230. issue 4. 2014-05-27. PMID:23780309. |
although several studies have emphasized a crucial role for the serotonergic system in the control of hippocampal excitability, the role of serotonin (5-ht) and its receptors in normal and pathologic conditions, such as temporal lobe epilepsy (tle), is still unclear. |
2014-05-27 |
2023-08-12 |
rat |
| María Esther Olvera-Cortés, Blanca Erika Gutiérrez-Guzmán, Elisa López-Loeza, J Jesús Hernández-Pérez, Miguel Angel López-Vázque. Serotonergic modulation of hippocampal theta activity in relation to hippocampal information processing. Experimental brain research. vol 230. issue 4. 2014-05-27. PMID:23990128. |
serotonin is recognized as the only neurotransmitter able to desynchronize the hippocampal electroencephalographic. |
2014-05-27 |
2023-08-12 |
Not clear |