| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lisa M McFadden, Glen R Hanson, Annette E Fleckenstei. The effects of methamphetamine self-administration on cortical monoaminergic deficits induced by subsequent high-dose methamphetamine administrations. Synapse (New York, N.Y.). vol 67. issue 12. 2014-03-25. PMID:23893609. |
second, and in contrast to our previous reports involving the hippocampus or striatum, meth self-administration caused persistent decreases in 5ht content as assessed 8 days after the final meth exposure. |
2014-03-25 |
2023-08-12 |
Not clear |
| Allison C Nugent, Earle E Bain, Paul J Carlson, Alexander Neumeister, Omer Bonne, Richard E Carson, William Eckelman, Peter Herscovitch, Carlos A Zarate, Dennis S Charney, Wayne C Drevet. Reduced post-synaptic serotonin type 1A receptor binding in bipolar depression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 8. 2014-03-13. PMID:23434290. |
across subjects the bpp in the mesiotemporal cortex was inversely correlated with trough plasma cortisol levels, consistent with preclinical literature indicating that hippocampal 5-ht(1a) receptor expression is inhibited by glucocorticoid receptor stimulation. |
2014-03-13 |
2023-08-12 |
human |
| Przemysław Nowak, Magdalena Kowalińska-Kania, Damian Nowak, Richard M Kostrzewa, Jolanta Malinowska-Borowsk. Antinociceptive effects of H₃ (R-methylhistamine) and GABA(B) (baclofen)-receptor ligands in an orofacial model of pain in rats. Neurotoxicity research. vol 24. issue 2. 2014-03-03. PMID:23463522. |
hplc/ed analysis showed that 5-hydroxytryptamine (5-ht) turnover was increased in hippocampus, thalamus, and brain stem of all formalin groups, excepting the baclofen group in which the balance of 5-ht metabolism was restored to control values. |
2014-03-03 |
2023-08-12 |
rat |
| Briony J Catlow, Shijie Song, Daniel A Paredes, Cheryl L Kirstein, Juan Sanchez-Ramo. Effects of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning. Experimental brain research. vol 228. issue 4. 2014-03-03. PMID:23727882. |
drugs that modulate serotonin (5-ht) synaptic concentrations impact neurogenesis and hippocampal (hpc)-dependent learning. |
2014-03-03 |
2023-08-12 |
mouse |
| Silvina L Diaz, Nicolas Narboux-Nême, Sara Trowbridge, Sophie Scotto-Lomassese, Felix B Kleine Borgmann, Sebastian Jessberger, Bruno Giros, Luc Maroteaux, Evan Deneris, Patricia Gaspa. Paradoxical increase in survival of newborn neurons in the dentate gyrus of mice with constitutive depletion of serotonin. The European journal of neuroscience. vol 38. issue 5. 2014-02-26. PMID:23841816. |
indeed, selective serotonin (5-ht) re-uptake inhibitors, which increase 5-ht transmission, enhance adult neurogenesis in the dentate gyrus (dg) of the hippocampus. |
2014-02-26 |
2023-08-12 |
mouse |
| Silvina L Diaz, Nicolas Narboux-Nême, Sara Trowbridge, Sophie Scotto-Lomassese, Felix B Kleine Borgmann, Sebastian Jessberger, Bruno Giros, Luc Maroteaux, Evan Deneris, Patricia Gaspa. Paradoxical increase in survival of newborn neurons in the dentate gyrus of mice with constitutive depletion of serotonin. The European journal of neuroscience. vol 38. issue 5. 2014-02-26. PMID:23841816. |
here, we analysed two genetic models of 5-ht depletion, the pet1(-/-) and the vmat2(f/f) ; sert(cre/+) mice, which have, respectively, 80 and 95% reductions in hippocampal 5-ht. |
2014-02-26 |
2023-08-12 |
mouse |
| Bernhard Luscher, Thomas Fuch. Adult hippocampal neurogenesis in the absence of serotonin (Commentary on Diaz et al.). The European journal of neuroscience. vol 38. issue 5. 2014-02-26. PMID:23992131. |
adult hippocampal neurogenesis in the absence of serotonin (commentary on diaz et al. |
2014-02-26 |
2023-08-12 |
Not clear |
| Wei-Hong Lv, Lu Zhang, Shu-Juan Wu, Sai-Zhen Chen, Xin-Bo Zhu, Jian-Chun Pa. [Analgesic effect of ferulic acid on CCI mice: behavior and neurobiological analysis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 38. issue 21. 2014-02-25. PMID:24494564. |
in an in-depth study, we found that the reason for these results was that ferulic acid was dose-dependent in increasing 5-ht and ne levels in hippocampus, frontal cortex and amygdale and could inhibit mao-a activity in mouse brains. |
2014-02-25 |
2023-08-12 |
mouse |
| Elodie Bouaziz, Michel Boris Emerit, Guilan Vodjdani, Vanessa Gautheron, Michel Hamon, Michèle Darmon, Justine Masso. Neuronal phenotype dependency of agonist-induced internalization of the 5-HT(1A) serotonin receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 1. 2014-02-24. PMID:24381289. |
because 5-ht(1a) receptor (5-ht(1a)r) internalization has been proposed as a possible mechanism underlying 5-ht(1a) autoreceptor desensitization, we examined whether this receptor could internalize under well controlled in vitro conditions in the llc-cpk1 cell line and in raphe or hippocampal neurons from rat embryos. |
2014-02-24 |
2023-08-12 |
rat |
| Hong-Mei Jia, Yu-Fei Feng, Yue-Tao Liu, Xing Chang, Lin Chen, Hong-Wu Zhang, Gang Ding, Zhong-Mei Zo. Integration of ¹H NMR and UPLC-Q-TOF/MS for a comprehensive urinary metabonomics study on a rat model of depression induced by chronic unpredictable mild stress. PloS one. vol 8. issue 5. 2014-02-18. PMID:23696839. |
moreover, the results of western blot analysis of aromatic l-amino acid decarboxylase (ddc) and indoleamine 2, 3-dioxygenase (ido) in the hippocampus of cums-treated rats indicated that depletion of 5-ht and tryptophan, production of 5-mt and altered expression of ddc and ido together played a key role in the initiation and progression of depression. |
2014-02-18 |
2023-08-12 |
rat |
| Masanori Ookubo, Hirohiko Kanai, Harusuke Aoki, Naoto Yamad. Antidepressants and mood stabilizers effects on histone deacetylase expression in C57BL/6 mice: Brain region specific changes. Journal of psychiatric research. vol 47. issue 9. 2014-02-14. PMID:23777937. |
to determine whether treatment with various antidepressants or mood stabilizers leads to region-specific changes, we investigated the effects of their subchronic (14 days of intraperitoneal injection) administration on the tissue concentration of monoamines, dopamine, serotonin, and norepinephrine, and the protein expression of acetylated histone h3 (ach3) and histone deacetylases (hdacs) in the mouse striatum (st), nucleus accumbens (acb), hippocampus (hip), cingulate cortex (cg), and amygdala (amy). |
2014-02-14 |
2023-08-12 |
mouse |
| Winanda W Ursinus, J Elizabeth Bolhuis, Johan J Zonderland, T Bas Rodenburg, Adriana S de Souza, Rudie E Koopmanschap, Bas Kemp, Gerdien A H Korte-Bouws, S Mechiel Korte, Cornelis G van Reene. Relations between peripheral and brain serotonin measures and behavioural responses in a novelty test in pigs. Physiology & behavior. vol 118. 2014-02-12. PMID:23685231. |
levels of serotonin, its metabolite and serotonin turnover were determined at 19weeks of age in the frontal cortex, hypothalamus and hippocampus. |
2014-02-12 |
2023-08-12 |
Not clear |
| Winanda W Ursinus, J Elizabeth Bolhuis, Johan J Zonderland, T Bas Rodenburg, Adriana S de Souza, Rudie E Koopmanschap, Bas Kemp, Gerdien A H Korte-Bouws, S Mechiel Korte, Cornelis G van Reene. Relations between peripheral and brain serotonin measures and behavioural responses in a novelty test in pigs. Physiology & behavior. vol 118. 2014-02-12. PMID:23685231. |
platelet serotonin level and brain serotonergic parameters in the hippocampus were interrelated. |
2014-02-12 |
2023-08-12 |
Not clear |
| Winanda W Ursinus, J Elizabeth Bolhuis, Johan J Zonderland, T Bas Rodenburg, Adriana S de Souza, Rudie E Koopmanschap, Bas Kemp, Gerdien A H Korte-Bouws, S Mechiel Korte, Cornelis G van Reene. Relations between peripheral and brain serotonin measures and behavioural responses in a novelty test in pigs. Physiology & behavior. vol 118. 2014-02-12. PMID:23685231. |
notably, the time spent exploring the test arena was significantly correlated with both platelet serotonin level and right hippocampal serotonin activity (turnover and concentration). |
2014-02-12 |
2023-08-12 |
Not clear |
| Lawrence S Own, Rimsha Iqbal, Paresh D Pate. Maternal separation alters serotonergic and HPA axis gene expression independent of separation duration in mice. Brain research. vol 1515. 2014-02-11. PMID:23548594. |
as adults, pups that experienced ms15 or ms180 demonstrated decreases in tryptophan hydroxylase 2 and serotonin transporter mrna in the dorsal raphe dorsalis and ventralis, and increases in glucocorticoid receptor mrna in the dentate gyrus of the hippocampus. |
2014-02-11 |
2023-08-12 |
mouse |
| Nicole A Northrop, Bryan K Yamamot. Cyclooxygenase activity contributes to the monoaminergic damage caused by serial exposure to stress and methamphetamine. Neuropharmacology. vol 72. 2014-02-11. PMID:23643743. |
the enhanced da and 5-ht depletions in the striatum, but not the hippocampus, were prevented by pretreatment with cox inhibitor, ketoprofen, during stress or during meth; however, ketoprofen did not attenuate the monoaminergic damage caused by meth alone. |
2014-02-11 |
2023-08-12 |
Not clear |
| Francesca Zoratto, Amanda L Tringle, Giancarlo Bellenchi, Luisa Speranza, Domenica Travaglini, Umberto di Porzio, Carla Perrone-Capano, Giovanni Laviola, Jean-Luc Dreyer, Walter Adrian. Impulsivity and home-cage activity are decreased by lentivirus-mediated silencing of serotonin transporter in the rat hippocampus. Neuroscience letters. vol 548. 2014-02-07. PMID:23769733. |
impulsivity and home-cage activity are decreased by lentivirus-mediated silencing of serotonin transporter in the rat hippocampus. |
2014-02-07 |
2023-08-12 |
rat |
| Francesca Zoratto, Amanda L Tringle, Giancarlo Bellenchi, Luisa Speranza, Domenica Travaglini, Umberto di Porzio, Carla Perrone-Capano, Giovanni Laviola, Jean-Luc Dreyer, Walter Adrian. Impulsivity and home-cage activity are decreased by lentivirus-mediated silencing of serotonin transporter in the rat hippocampus. Neuroscience letters. vol 548. 2014-02-07. PMID:23769733. |
this phenotype is consistent with available data both on 5-ht manipulations and hippocampal lesions. |
2014-02-07 |
2023-08-12 |
rat |
| Hosung Lee, Makoto Ohno, Shigeo Ohta, Toshio Mikam. Regular moderate or intense exercise prevents depression-like behavior without change of hippocampal tryptophan content in chronically tryptophan-deficient and stressed mice. PloS one. vol 8. issue 7. 2014-02-03. PMID:23861751. |
regular exercise, whether moderate or intense, prevents depression-like behavior with an improvement of adult hippocampal cell proliferation and survival and without the recovery of 5-ht. |
2014-02-03 |
2023-08-12 |
mouse |
| Simon Trent, Rachel Dean, Bonnie Veit, Tommaso Cassano, Gaurav Bedse, Obah A Ojarikre, Trevor Humby, William Davie. Biological mechanisms associated with increased perseveration and hyperactivity in a genetic mouse model of neurodevelopmental disorder. Psychoneuroendocrinology. vol 38. issue 8. 2014-01-31. PMID:23276394. |
hyperactivity), elevated hippocampal serotonin (5-ht) levels, and reduced serum levels of dehydroepiandrosterone (dhea). |
2014-01-31 |
2023-08-12 |
mouse |