| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Franck Chenu, Mostafa El Mansari, Pierre Blie. Electrophysiological effects of repeated administration of agomelatine on the dopamine, norepinephrine, and serotonin systems in the rat brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 2. 2013-10-17. PMID:22871919. |
after 14 days, the administration of agomelatine induced an increase in: (1) the number of spontaneously active da neurons (p<0.05), (2) the bursting activity of da neurons (bursts/min, p<0.01 and percentage of spikes occurring in bursts, p<0.05), (3) the firing rate of drn-5-ht neurons (p<0.05), and (4) the tonic activation of postsynaptic 5-ht(1a) receptors located in the hippocampus. |
2013-10-17 |
2023-08-12 |
rat |
| Andrew E Arrant, Hikma Jemal, Cynthia M Kuh. Adolescent male rats are less sensitive than adults to the anxiogenic and serotonin-releasing effects of fenfluramine. Neuropharmacology. vol 65. 2013-10-17. PMID:23103347. |
adult rats had higher tissue serotonin content than adolescents in the prefrontal cortex, amygdala, and hippocampus, but the rate of serotonin synthesis was similar between age groups. |
2013-10-17 |
2023-08-12 |
rat |
| Monzurul Amin Roni, Shafiqur Rahma. Antidepressant-like effects of lobeline in mice: behavioral, neurochemical, and neuroendocrine evidence. Progress in neuro-psychopharmacology & biological psychiatry. vol 41. 2013-10-17. PMID:23200829. |
further, the effects of lobeline on fss-induced increased in norepinephrine (ne) and serotonin levels in the prefrontal cortex (pfc) and hippocampus were determined using high performance liquid chromatography. |
2013-10-17 |
2023-08-12 |
mouse |
| Karen L Smith, Gemma K Ford, David S Jessop, David P Fin. Behavioural, neurochemical and neuroendocrine effects of the endogenous β-carboline harmane in fear-conditioned rats. Journal of psychopharmacology (Oxford, England). vol 27. issue 2. 2013-09-30. PMID:23015542. |
harmane increased plasma acth and corticosterone concentrations, and serotonin (in hypothalamus, amygdaloid cortex, prefrontal cortex and hippocampus) and noradrenaline (prefrontal cortex) content, irrespective of fear-conditioning. |
2013-09-30 |
2023-08-12 |
rat |
| Li Hu, Jia Liang, Shu-Ying Jin, Yan-Jing Han, Jun Lu, Ya T. [Progress of researches on mechanisms of acupuncture underlying improvement of depression in the past five years]. Zhen ci yan jiu = Acupuncture research. vol 38. issue 3. 2013-09-24. PMID:24006675. |
in the present paper, the authors summarize mechanisms of acupuncture for depression from 1) upregulating levels of monoamine neurotransmitters, gamma-aminobutyric acid, 5-ht, receptor binding, and hypothalamic neuropeptide y, beta-endorphine, and mu-receptor expression, and down-regulating hippocampal glutamate content, etc. |
2013-09-24 |
2023-08-12 |
Not clear |
| M Embree, V Michopoulos, J R Votaw, R J Voll, J Mun, J S Stehouwer, M M Goodman, M E Wilson, M M Sánche. The relation of developmental changes in brain serotonin transporter (5HTT) and 5HT1A receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5HTT genotype. Neuroscience. vol 228. 2013-09-23. PMID:23079633. |
the increase in 5ht1a bp(nd) in these socially housed female rhesus monkeys is a robust finding, occurring across all groups, regardless of social status or 5htt genotype, and occurring in the left and right hemispheres of all prefrontal regions studied, as well as the amygdala, hippocampus, hypothalamus, and raphe nuclei. |
2013-09-23 |
2023-08-12 |
human |
| A Akubuiro, M Bridget Zimmerman, L L Boles Ponto, S A Walsh, J Sunderland, L McCormick, M Sing. Hyperactive hypothalamus, motivated and non-distractible chronic overeating in ADAR2 transgenic mice. Genes, brain, and behavior. vol 12. issue 3. 2013-09-23. PMID:23323881. |
the results indicate that adar2 transgenic mice exhibit, (1) a food preference for diets with higher fat content, (2) significantly increased food intake that is non-distractible in a competing reward environment, (3) significantly increased messenger rna (mrna) expressions of adar2, serotonin 2c receptor (5ht2c r), d1, d2 and mu opioid receptors and no change in corticotropin-releasing hormone mrnas and significantly reduced adar2 protein expression in the hypothalamus, (4) significantly increased d1 receptor and altered bioamines with no change in adar2, mu opioid and d2 receptor mrna expression in the striatum and (5) significantly greater glucose metabolism in the hypothalamus, brain stem, right hippocampus, left and right mid brain regions and suprascapular peripheral tissue than controls. |
2013-09-23 |
2023-08-12 |
mouse |
| Yi Liu, Genguang Jia, Lingshan Gou, Lingyan Sun, Xiaobin Fu, Nuo Lan, Sai Li, Xiaoxing Yi. Antidepressant-like effects of tea polyphenols on mouse model of chronic unpredictable mild stress. Pharmacology, biochemistry, and behavior. vol 104. 2013-09-17. PMID:23290936. |
our results showed that cums significantly decreased the levels of serum serotonin (5-ht) and norepinephrine (ne) in the hippocampus, the prefrontal cortex and serum, and the activities of superoxide dismutase (sod) and catalase (cat), with an increase in lipid peroxidation level as well as a reduction in glutathione (gsh) level and an elevation in the production of malondialdehyde (mda) in the hippocampus and the prefrontal cortex. |
2013-09-17 |
2023-08-12 |
mouse |
| Jana Tchekalarova, Zlatina Petkova, Daniela Pechlivanova, Slavianka Moyanova, Lidia Kortenska, Rumiana Mitreva, Valentin Lozanov, Dimitrina Atanasova, Nikolai Lazarov, Alexander Stoyne. Prophylactic treatment with melatonin after status epilepticus: effects on epileptogenesis, neuronal damage, and behavioral changes in a kainate model of temporal lobe epilepsy. Epilepsy & behavior : E&B. vol 27. issue 1. 2013-09-12. PMID:23435277. |
melatonin reduced the neuronal damage in the ca1 area of the hippocampus and piriform cortex and recovered the decrease of hippocampal serotonin (5-ht) level in rats with epilepsy. |
2013-09-12 |
2023-08-12 |
rat |
| Wendy K Adams, Adam L Halberstadt, Maarten van den Buus. Hippocampal serotonin depletion unmasks differences in the hyperlocomotor effects of phencyclidine and MK-801: quantitative versus qualitative analyses. Frontiers in pharmacology. vol 4. 2013-09-06. PMID:24009584. |
hippocampal serotonin depletion unmasks differences in the hyperlocomotor effects of phencyclidine and mk-801: quantitative versus qualitative analyses. |
2013-09-06 |
2023-08-12 |
rat |
| Soo Jeong Kim, Lee Lee, Ji Hyun Kim, Tae Hee Lee, Insop Shi. Antidepressant-like effects of lycii radicis cortex and betaine in the forced swimming test in rats. Biomolecules & therapeutics. vol 21. issue 1. 2013-09-06. PMID:24009863. |
to investigate antidepressant-like effect, serotonin (5-ht) and norepinephrine (ne) were examined in the hippocampus and hypothalamus of rats. |
2013-09-06 |
2023-08-12 |
human |
| Soo Jeong Kim, Lee Lee, Ji Hyun Kim, Tae Hee Lee, Insop Shi. Antidepressant-like effects of lycii radicis cortex and betaine in the forced swimming test in rats. Biomolecules & therapeutics. vol 21. issue 1. 2013-09-06. PMID:24009863. |
bt (100 mg/kg) significantly increased 5-ht levels in the hypothalamus and hippocampus of rats. |
2013-09-06 |
2023-08-12 |
human |
| Soo Jeong Kim, Lee Lee, Ji Hyun Kim, Tae Hee Lee, Insop Shi. Antidepressant-like effects of lycii radicis cortex and betaine in the forced swimming test in rats. Biomolecules & therapeutics. vol 21. issue 1. 2013-09-06. PMID:24009863. |
taken together, these results demonstrated that improvement in the behavioral changes after lrc and bt administration may be mediated by elevation of 5-ht level in the hypothalamus and hippocampus, indicating a possible antidepressant-like activity. |
2013-09-06 |
2023-08-12 |
human |
| Ruyun Zhou, Shinsuke Niwa, Laurent Guillaud, Ying Tong, Nobutaka Hirokaw. A molecular motor, KIF13A, controls anxiety by transporting the serotonin type 1A receptor. Cell reports. vol 3. issue 2. 2013-09-03. PMID:23438369. |
the cell-surface expression level of the 5ht(1a)r was reduced in kif13a-knockdown neuroblastoma cells and kif13a(-/-) hippocampal neurons. |
2013-09-03 |
2023-08-12 |
mouse |
| Rebecca E Horton, Deana M Apple, W Anthony Owens, Nicole L Baganz, Sonia Cano, Nathan C Mitchell, Melissa Vitela, Georgianna G Gould, Wouter Koek, Lynette C Daw. Decynium-22 enhances SSRI-induced antidepressant-like effects in mice: uncovering novel targets to treat depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 25. 2013-08-30. PMID:23785165. |
this antidepressant-like activity of d-22 was attenuated in oct3 ko mice, whereas the effect of d-22 to inhibit 5-ht clearance in the ca3 region of hippocampus persisted. |
2013-08-30 |
2023-08-12 |
mouse |
| Maria A Tikhonova, Alexander V Kulikov, Daria V Bazovkina, Elizabeth A Kulikova, Anton S Tsybko, Ekaterina Yu Bazhenova, Vladimir S Naumenko, Andrey E Akulov, Mikhail P Moshkin, Nina K Popov. Hereditary catalepsy in mice is associated with the brain dysmorphology and altered stress response. Behavioural brain research. vol 243. 2013-08-28. PMID:23295395. |
the multivariate factor analysis revealed interactions between the basal levels and the stress-induced alterations of 5-ht metabolism in the hippocampus and midbrain suggesting the interaction between multiple alterations in 5-ht neurotransmission in several brain structures in the regulation of hereditary catalepsy. |
2013-08-28 |
2023-08-12 |
mouse |
| Ann Van der Jeugd, David Blum, Sylvie Raison, Sabiha Eddarkaoui, Luc Buée, Rudi D'Hoog. Observations in THY-Tau22 mice that resemble behavioral and psychological signs and symptoms of dementia. Behavioural brain research. vol 242. 2013-08-27. PMID:23247080. |
moreover, these changes were linked to a decreased hippocampal concentration in serotonin, or 5-hydroxytryptamine (5-ht), and 5-hydroxyindoleacetic acid (5-hiaa), the main metabolite of serotonin. |
2013-08-27 |
2023-08-12 |
mouse |
| Jenessa S Price, Judith Strong, James Eliassen, Tim McQueeny, Megan Miller, Claudia B Padula, Paula Shear, Krista Lisdah. Serotonin transporter gene moderates associations between mood, memory and hippocampal volume. Behavioural brain research. vol 242. 2013-08-27. PMID:23266326. |
serotonin transporter gene moderates associations between mood, memory and hippocampal volume. |
2013-08-27 |
2023-08-12 |
Not clear |
| O Castellano, M Arji, C Sancho, J Carro, A S Riolobos, V Molina, R Gómez-Nieto, José de Anchieta de Castro E Horta, M J Herrero-Turrión, D E Lópe. Chronic administration of risperidone in a rat model of schizophrenia: a behavioural, morphological and molecular study. Behavioural brain research. vol 242. 2013-08-27. PMID:23291154. |
our results show that during their adult lives the animals with hippocampal lesions exhibit different alterations, mainly at behavioural level and in the gene expression of dopamine d(2) and 5-ht(2a) receptors. |
2013-08-27 |
2023-08-12 |
rat |
| Stella Manta, Mostafa El Mansari, Guy Debonnel, Pierre Blie. Electrophysiological and neurochemical effects of long-term vagus nerve stimulation on the rat monoaminergic systems. The international journal of neuropsychopharmacology. vol 16. issue 2. 2013-08-21. PMID:22717062. |
this study was aimed at examining the effect of vns on extracellular 5-ht, ne and dopamine (da) levels in different brain areas using in vivo microdialysis, on ne transmission in the hippocampus, and da neuronal firing activity using electrophysiology. |
2013-08-21 |
2023-08-12 |
rat |