| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Brunel, C de Montign. Validation of the I.T50 method for assessing neuronal responsiveness to microiontophoretic applications: a single-cell recording study. Journal of pharmacological methods vol 19 issue 1 1988 3367646 |
in the present study, it was found that the use of microiontophoretic currents greater than 3 na yielded consistent i.t50 values when serotonin (5-ht) was applied to rat hippocampal pyramidal neurons. |
1988-06-13 |
2022-01-10 |
Not clear |
| J L Yakel, L O Trussell, M B Jackso. Three serotonin responses in cultured mouse hippocampal and striatal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 8 issue 4 1988 2965756 |
serotonin (5-ht) produced 3 different types of responses in neurons of mouse hippocampal and striatal cell cultures. |
1988-05-26 |
2022-01-10 |
Not clear |
| J L Yakel, L O Trussell, M B Jackso. Three serotonin responses in cultured mouse hippocampal and striatal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 8 issue 4 1988 2965756 |
5-methoxy-n,n-dimethyltryptamine also produced this response in both striatal and hippocampal cultures and had no effect on the other 5-ht currents observed in this study. |
1988-05-26 |
2022-01-10 |
Not clear |
| H Y Wang, E Friedma. Chronic lithium: desensitization of autoreceptors mediating serotonin release. Psychopharmacology vol 94 issue 3 1988 3128806 |
the effect of chronic lithium treatment on k+-induced release of preloaded [3h] serotonin [( 3h]5-ht) from brain slices and its regulation by the presynaptic serotonin autoreceptors were investigated in superfused cortical, hippocampal and hypothalamic brain slices. |
1988-05-13 |
2022-01-10 |
Not clear |
| R Andrade, R A Nicol. Pharmacologically distinct actions of serotonin on single pyramidal neurones of the rat hippocampus recorded in vitro. The Journal of physiology vol 394 issue 1988 3443977 |
in summary 5-ht acts on at least two distinct receptors on hippocampal pyramidal cells, one coupled to the opening of potassium channels and a second coupled to a decrease in a resting potassium conductance and a decrease in the a.h.p. |
1988-05-12 |
2022-01-10 |
Not clear |
| H Gozlan, M Ponchant, G Daval, D Verge, F Menard, A Vanhove, J P Beaucourt, M Hamo. 125I-Bolton-Hunter-8-methoxy-2-[N-propyl-N-propylamino]tetralin as a new selective radioligand of 5-HT1A sites in the rat brain. In vitro binding and autoradiographic studies. The Journal of pharmacology and experimental therapeutics vol 244 issue 2 1988 2964524 |
in vitro binding assays with 125i-[8-methoxy-2-[n-propyl-n-(3'-iodo-4'-hydroxyphenyl)-propionamido -n'- propylamino] tetralin] (125i-bh-8-meo-n-pat), a 125i-labeled derivative of the potent serotonin (5-ht) agonist 8-hydroxy-2-[di-n-propylamino]tetralin [( 3h]-8-oh-dpat), showed that this compound recognized specific sites with nanomolar affinity for 5-ht and 5-ht1a ligands such as spiroxatrine, ipsapirone, buspirone and gepirone in rat hippocampal membranes. |
1988-04-12 |
2022-01-10 |
Not clear |
| A Dumuis, M Sebben, J Bockaer. Pharmacology of 5-hydroxytryptamine-1A receptors which inhibit cAMP production in hippocampal and cortical neurons in primary culture. Molecular pharmacology vol 33 issue 2 1988 2828913 |
serotonin (5-hydroxytryptamine, 5-ht) inhibited the formation of camp promoted by vasoactive intestinal polypeptide, plus forskolin, in mouse hippocampal and cortical neurons in primary culture. |
1988-03-24 |
2022-01-10 |
Not clear |
| A Dumuis, M Sebben, J Bockaer. Pharmacology of 5-hydroxytryptamine-1A receptors which inhibit cAMP production in hippocampal and cortical neurons in primary culture. Molecular pharmacology vol 33 issue 2 1988 2828913 |
the rank order of potencies of classical 5-ht1 agonists in inhibiting camp formation in hippocampal neurons was 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) greater than 5-carboxamidotryptamine (5-ct) greater than d-lysergic acid diethylamide greater than 5-ht greater than 5-methoxy-n,n-dimethyltryptamine (5-meo-n,n-dmt) greater than ru 24969 greater than ipsapirone greater than bufotenine greater than buspirone [half-maximal efficacy (ec50) = 7, 18, 30, 52, 90, 102, 100, 110, and 128 nm, respectively]. |
1988-03-24 |
2022-01-10 |
Not clear |
| A Dumuis, M Sebben, J Bockaer. Pharmacology of 5-hydroxytryptamine-1A receptors which inhibit cAMP production in hippocampal and cortical neurons in primary culture. Molecular pharmacology vol 33 issue 2 1988 2828913 |
the pharmacological characterization of the 5-ht receptor negatively coupled to adenylate cyclase in mouse embryonic cortical neurons indicates that it differs from the 5-ht1a receptor found in hippocampal neurons. |
1988-03-24 |
2022-01-10 |
Not clear |
| M B Speisky, H Kalan. Retention of ethanol tolerance by desglycinamide-arginine-vasopressin occurs in the absence of changes in hippocampal serotonin synthesis. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement vol 1 issue 1988 3426715 |
while the mechanism underlying this effect is unknown, we have reported that specific depletion of hippocampal serotonin (5-ht) prevents the prolongation of tolerance by dgavp. |
1988-03-23 |
2022-01-10 |
Not clear |
| M B Speisky, H Kalan. Retention of ethanol tolerance by desglycinamide-arginine-vasopressin occurs in the absence of changes in hippocampal serotonin synthesis. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement vol 1 issue 1988 3426715 |
when administered acutely, dgavp had no effect on the rates of hippocampal or septal 5-ht synthesis in naive rats, as assessed by the nsd 1015 method. |
1988-03-23 |
2022-01-10 |
Not clear |
| M B Speisky, H Kalan. Retention of ethanol tolerance by desglycinamide-arginine-vasopressin occurs in the absence of changes in hippocampal serotonin synthesis. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement vol 1 issue 1988 3426715 |
similarly, no significant differences were found in the levels of hippocampal 5-ht or 5-hiaa. |
1988-03-23 |
2022-01-10 |
Not clear |
| M B Speisky, H Kalan. Retention of ethanol tolerance by desglycinamide-arginine-vasopressin occurs in the absence of changes in hippocampal serotonin synthesis. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement vol 1 issue 1988 3426715 |
while the lack of changes in hippocampal 5-ht synthesis argues against a presynaptic dgavp-5-ht interaction, the possibility remains of a peptide modulation of 5-ht postsynaptic actions. |
1988-03-23 |
2022-01-10 |
Not clear |
| D M Stone, G R Hanson, J W Gib. Differences in the central serotonergic effects of methylenedioxymethamphetamine (MDMA) in mice and rats. Neuropharmacology vol 26 issue 11 1988 2448703 |
whereas neostriatal concentrations of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in mouse were transiently decreased after a single moderately high dose of mdma (15 mg/kg), mouse neostriatal or hippocampal tryptophan hydroxylase activity was not significantly affected, even after a dose of 60 mg/kg. |
1988-03-09 |
2022-01-10 |
Not clear |
| E Friedman, H Y Wan. Effect of chronic lithium treatment on 5-hydroxytryptamine autoreceptors and release of 5-[3H]hydroxytryptamine from rat brain cortical, hippocampal, and hypothalamic slices. Journal of neurochemistry vol 50 issue 1 1988 2826685 |
effect of chronic lithium treatment on 5-hydroxytryptamine autoreceptors and release of 5-[3h]hydroxytryptamine from rat brain cortical, hippocampal, and hypothalamic slices. |
1988-01-26 |
2022-01-10 |
Not clear |
| A L Vale, D J Balfou. The role of hippocampal 5-HT in the effects of nicotine on habituation to an X-maze. European journal of pharmacology vol 141 issue 2 1988 2445590 |
the role of hippocampal 5-ht in the effects of nicotine on habituation to an x-maze. |
1988-01-19 |
2022-01-10 |
Not clear |
| A Baskys, C E Niesen, P L Carle. Altered modulatory actions of serotonin on dentate granule cells of aged rats. Brain research vol 419 issue 1-2 1988 3676719 |
the effects of serotonin (5-ht) on dentate granule (dg) neurons in hippocampal slices taken from young mature (6-8 months) and old (25-29 months) rats were compared. |
1988-01-11 |
2022-01-10 |
Not clear |
| K F Martin, R Maso. Isapirone is a partial agonist at 5-hydroxytryptamine 1A (5-HT1A) receptors in the rat hippocampus: electrophysiological evidence. European journal of pharmacology vol 141 issue 3 1987 2889611 |
using iontophoretic techniques we observed that in vivo isapirone (tvx q 7821), a selective ligand for the 5-ht1a binding site, at low ejection currents (5-30 na) antagonised 5-ht and 8-hydroxy-2-(di-n-propylamino) tetralin (dpat)-induced suppression of hippocampal unit activity, with little effect on baseline firing rate itself. |
1987-12-16 |
2022-01-10 |
Not clear |
| T J Feuerstein, C Allgaier, G Herttin. Possible involvement of protein kinase C (PKC) in the regulation of electrically evoked serotonin (5-HT) release from rabbit hippocampal slices. European journal of pharmacology vol 139 issue 3 1987 3666005 |
possible involvement of protein kinase c (pkc) in the regulation of electrically evoked serotonin (5-ht) release from rabbit hippocampal slices. |
1987-11-27 |
2022-01-10 |
Not clear |
| T J Feuerstein, C Allgaier, G Herttin. Possible involvement of protein kinase C (PKC) in the regulation of electrically evoked serotonin (5-HT) release from rabbit hippocampal slices. European journal of pharmacology vol 139 issue 3 1987 3666005 |
protein kinase c (pkc)-activating phorbol esters enhanced the electrically evoked 5-ht release from rabbit hippocampal slices preincubated with [3h]5-ht. |
1987-11-27 |
2022-01-10 |
Not clear |