Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
M De Vivo, S Maayan. Characterization of the 5-hydroxytryptamine1a receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranes. The Journal of pharmacology and experimental therapeutics vol 238 issue 1 1986 2941565 |
in guinea pig hippocampal membranes 8-hydroxy-2-(di-n-propylamino)tetralin, d-lysergic acid diethylamide, 5-ht and buspirone were potent in inhibiting forskolin-stimulated adenylate cyclase activity, with ec50 values of 18, 24, 53 and 146 nm, respectively. |
1986-08-20 |
2022-01-10 |
Not clear |
M De Vivo, S Maayan. Characterization of the 5-hydroxytryptamine1a receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranes. The Journal of pharmacology and experimental therapeutics vol 238 issue 1 1986 2941565 |
in rat hippocampal membranes, 8-hydroxy-2-(di-n-propylamino)tetralin, d-lysergic acid diethylamide, 5-ht and buspirone were potent agonists and exhibited the same rank order of potency as in guinea pig hippocampal membranes. |
1986-08-20 |
2022-01-10 |
Not clear |
P Blier, C De Montigny, A J Azzar. Modification of serotonergic and noradrenergic neurotransmissions by repeated administration of monoamine oxidase inhibitors: electrophysiological studies in the rat central nervous system. The Journal of pharmacology and experimental therapeutics vol 237 issue 3 1986 2423685 |
the net effect of repeated administration of monoamine oxidase inhibitors (maoi) on central serotonergic (5-ht) and noradrenergic (ne) neurotransmissions was studied by assessing the responsiveness of hippocampal pyramidal neurons to microiontophoretically applied 5-ht and ne and the response of these neurons to the electrical activation of the 5-ht and ne ascending pathways. |
1986-07-16 |
2022-01-10 |
Not clear |
P Blier, C De Montigny, A J Azzar. Modification of serotonergic and noradrenergic neurotransmissions by repeated administration of monoamine oxidase inhibitors: electrophysiological studies in the rat central nervous system. The Journal of pharmacology and experimental therapeutics vol 237 issue 3 1986 2423685 |
the responsiveness of hippocampal pyramidal neurons to 5-ht was decreased by the long-term clorgyline treatment, but not by deprenyl and phenelzine, whereas that to ne was not altered by any of the treatments. |
1986-07-16 |
2022-01-10 |
Not clear |
T Nishikawa, B Scatto. Neuroanatomical site of the inhibitory influence of anxiolytic drugs on central serotonergic transmission. Brain research vol 371 issue 1 1986 2871894 |
the decrease of hippocampal 5-ht synthesis induced by diazepam (5 mg/kg, s.c.) was antagonized by the benzodiazepine antagonist ro 15-1788 (2 x 30 mg/kg, s.c.) but not by bicuculline (2 x 1 mg/kg, s.c.). |
1986-06-30 |
2022-01-10 |
Not clear |
T Nishikawa, B Scatto. Neuroanatomical site of the inhibitory influence of anxiolytic drugs on central serotonergic transmission. Brain research vol 371 issue 1 1986 2871894 |
to diminish hippocampal 5-ht synthesis. |
1986-06-30 |
2022-01-10 |
Not clear |
T Nishikawa, B Scatto. Neuroanatomical site of the inhibitory influence of anxiolytic drugs on central serotonergic transmission. Brain research vol 371 issue 1 1986 2871894 |
local infusion of diazepam (15 micrograms) of flurazepam (1.5 micrograms) into the hippocampus of conscious rats (via indwelling cannulae) markedly reduced 5-ht synthesis in this brain area whereas infusion of these drugs into the raph\xc3\xa9 medianus (origin of the serotonergic afferents to the hippocampus) failed to affect hippocampal 5-ht synthesis. |
1986-06-30 |
2022-01-10 |
Not clear |
M Devivo, S Maayan. Inhibition of forskolin-stimulated adenylate cyclase activity by 5-HT receptor agonists. European journal of pharmacology vol 119 issue 3 1986 2936612 |
we measured the inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig hippocampal membranes by 5-ht, 5-carboxamidotryptamine (cat) and 8-hydroxy-2-(di-n-propylamino) tetralin (pat). |
1986-04-03 |
2022-01-10 |
Not clear |
P F Gately, D S Segal, M A Geye. The behavioral effects of depletions of brain serotonin induced by 5,7-dihydroxytryptamine vary with time after administration. Behavioral and neural biology vol 45 issue 1 1986 3954713 |
liquid chromatographic assays revealed that this treatment did not significantly alter catecholamine levels but depleted hippocampal 5ht by 92% and striatal 5ht by 45%. |
1986-04-02 |
2022-01-10 |
Not clear |
P F Gately, S L Poon, D S Segal, M A Geye. Depletion of brain serotonin by 5,7-dihydroxytryptamine alters the response to amphetamine and the habituation of locomotor activity in rats. Psychopharmacology vol 87 issue 4 1986 3936096 |
in a separate set of animals, liquid chromatographic assays revealed that this treatment did not significantly alter catecholamine levels but depleted hippocampal 5ht by 80-90% and caudate 5ht by 30-42% as early as 24 h after administration of 5,7-dht. |
1986-02-17 |
2022-01-10 |
Not clear |
S G Beck, W P Clarke, J Goldfar. Spiperone differentiates multiple 5-hydroxytryptamine responses in rat hippocampal slices in vitro. European journal of pharmacology vol 116 issue 1-2 1985 2932343 |
spiperone differentiates multiple 5-hydroxytryptamine responses in rat hippocampal slices in vitro. |
1985-12-18 |
2022-01-10 |
Not clear |
P Blier, C De Montign. Short-term lithium administration enhances serotonergic neurotransmission: electrophysiological evidence in the rat CNS. European journal of pharmacology vol 113 issue 1 1985 2995061 |
a first series of experiments served to assess the responsiveness of ca3 hippocampal pyramidal neurons to microiontophoretically applied serotonin (5-ht) and norepinephrine (ne). |
1985-11-12 |
2022-01-10 |
Not clear |
L K Chomicka, A M Koneck. Spontaneously prolonged dioestrus and serotonin in various regions of the rat brain. Journal of neural transmission vol 63 issue 1 1985 2411854 |
no significant difference was observed with 5-ht and 5-hiaa concentrations in the hippocampus (hipp). |
1985-10-18 |
2022-01-10 |
Not clear |
T J Feuerstein, G Hertting, R Jackisc. Endogenous noradrenaline as modulator of hippocampal serotonin (5-HT)-release. Dual effects of yohimbine, rauwolscine and corynanthine as alpha-adrenoceptor antagonists and 5-HT-receptor agonists. Naunyn-Schmiedeberg's archives of pharmacology vol 329 issue 3 1985 2991775 |
endogenous noradrenaline as modulator of hippocampal serotonin (5-ht)-release. |
1985-09-19 |
2022-01-10 |
Not clear |
T J Feuerstein, G Hertting, R Jackisc. Endogenous noradrenaline as modulator of hippocampal serotonin (5-HT)-release. Dual effects of yohimbine, rauwolscine and corynanthine as alpha-adrenoceptor antagonists and 5-HT-receptor agonists. Naunyn-Schmiedeberg's archives of pharmacology vol 329 issue 3 1985 2991775 |
the modulation of hippocampal serotonin (5-ht)-release by noradrenaline was studied in rabbit hippocampal slices, which were preincubated with 3h-serotonin and then superfused continuously. |
1985-09-19 |
2022-01-10 |
Not clear |
T Glaser, J Trabe. Binding of the putative anxiolytic TVX Q 7821 to hippocampal 5-hydroxytryptamine (5-HT) recognition sites. Naunyn-Schmiedeberg's archives of pharmacology vol 329 issue 3 1985 3160954 |
binding of the putative anxiolytic tvx q 7821 to hippocampal 5-hydroxytryptamine (5-ht) recognition sites. |
1985-09-19 |
2022-01-10 |
Not clear |
P K Stanton, J M Sarve. Depletion of norepinephrine, but not serotonin, reduces long-term potentiation in the dentate gyrus of rat hippocampal slices. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 5 issue 8 1985 4040556 |
therefore, we have examined the effects of depletion of ne or 5-ht on ltp in the dentate and field ca1 of the isolated in vitro hippocampal slice preparation. |
1985-09-19 |
2022-01-10 |
Not clear |
P K Stanton, J M Sarve. Depletion of norepinephrine, but not serotonin, reduces long-term potentiation in the dentate gyrus of rat hippocampal slices. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 5 issue 8 1985 4040556 |
these results suggest that endogenous hippocampal ne is more important to ltp in the dentate than is endogenous 5-ht. |
1985-09-19 |
2022-01-10 |
Not clear |
A V Juorio, A J Greensha. Tryptamine concentrations in areas of 5-hydroxytryptamine terminal innervation after electrolytic lesions of midbrain raphe nuclei. Journal of neurochemistry vol 45 issue 2 1985 2409228 |
to assess this hypothesis, we have investigated the effects of electrolytic lesions of the median and dorsal raphe nuclei on striatal, hypothalamic, and hippocampal concentrations of tryptamine, 5-hydroxytryptamine (5-ht), and 5-hydroxyindoleacetic acid. |
1985-08-20 |
2022-01-10 |
Not clear |
S Narumi, Y Nagai, M Kakihana, N Yamazaki, A Nagaoka, Y Nagaw. Effects of idebenone (CV-2619) on metabolism of monoamines, especially serotonin, in the brain of normal rats and rats with cerebral ischemia. Japanese journal of pharmacology vol 37 issue 3 1985 2582171 |
cv-2619 slightly inhibited and pca markedly inhibited 5-ht uptake into hippocampal slices. |
1985-07-17 |
2022-01-10 |
Not clear |