| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L D Popova, I M Vasyl'iev. [Blood plasma testosterone and brain serotonin levels in aggressive and submissive rats of different age groups]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 58. issue 6. 2013-04-08. PMID:23530415. |
correlation between the level of testosterone in blood plasma and serotonin content in hippocampus and frontal cortex was investigated in aggressive and submissive rats of different age groups. |
2013-04-08 |
2023-08-12 |
rat |
| L D Popova, I M Vasyl'iev. [Blood plasma testosterone and brain serotonin levels in aggressive and submissive rats of different age groups]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 58. issue 6. 2013-04-08. PMID:23530415. |
in submissive males we found considerable decrease of the serotonin level in frontal cortex and hippocampus as compared with balanced and aggressive ones. |
2013-04-08 |
2023-08-12 |
rat |
| J M Launay, S Mouillet-Richard, A Baudry, M Pietri, O Kellerman. Raphe-mediated signals control the hippocampal response to SRI antidepressants via miR-16. Translational psychiatry. vol 1. 2013-04-04. PMID:22833211. |
serotonin reuptake inhibitor (sri) antidepressants such as fluoxetine (prozac), promote hippocampal neurogenesis. |
2013-04-04 |
2023-08-12 |
mouse |
| J M Launay, S Mouillet-Richard, A Baudry, M Pietri, O Kellerman. Raphe-mediated signals control the hippocampal response to SRI antidepressants via miR-16. Translational psychiatry. vol 1. 2013-04-04. PMID:22833211. |
fluoxetine, acting on serotonergic raphe neurons, decreases the amount of mir-16 in the hippocampus, which in turn increases the levels of the serotonin transporter (sert), the target of sri, and that of bcl-2 and the number of cells positive for doublecortin, a marker of neuronal maturation. |
2013-04-04 |
2023-08-12 |
mouse |
| Tomoko Horisawa, Takeo Ishiyama, Michiko Ono, Tadashi Ishibashi, Mutsuo Taij. Binding of lurasidone, a novel antipsychotic, to rat 5-HT7 receptor: analysis by [3H]SB-269970 autoradiography. Progress in neuro-psychopharmacology & biological psychiatry. vol 40. 2013-03-26. PMID:23367506. |
we found that 5-ht(7) receptors are abundantly localized in brain limbic structures, including the lateral septum, thalamus, hypothalamus, hippocampus, and amygdala. |
2013-03-26 |
2023-08-12 |
human |
| Craig P Motbey, Emily Karanges, Kong M Li, Shane Wilkinson, Adam R Winstock, John Ramsay, Callum Hicks, Michael D Kendig, Naomi Wyatt, Paul D Callaghan, Iain S McGrego. Mephedrone in adolescent rats: residual memory impairment and acute but not lasting 5-HT depletion. PloS one. vol 7. issue 9. 2013-03-06. PMID:23029034. |
striatal dopamine (da) levels were increased 1 h following either meth or mmc while striatal and hippocampal serotonin (5-ht) levels were decreased 1 h following mmc but not meth. |
2013-03-06 |
2023-08-12 |
rat |
| A Mogha, S R Guariglia, P R Debata, G Y Wen, P Banerje. Serotonin 1A receptor-mediated signaling through ERK and PKCα is essential for normal synaptogenesis in neonatal mouse hippocampus. Translational psychiatry. vol 2. 2013-03-04. PMID:22832728. |
serotonin 1a receptor-mediated signaling through erk and pkcα is essential for normal synaptogenesis in neonatal mouse hippocampus. |
2013-03-04 |
2023-08-12 |
mouse |
| A Mogha, S R Guariglia, P R Debata, G Y Wen, P Banerje. Serotonin 1A receptor-mediated signaling through ERK and PKCα is essential for normal synaptogenesis in neonatal mouse hippocampus. Translational psychiatry. vol 2. 2013-03-04. PMID:22832728. |
stimulation of the hippocampal 5-ht(1a)-r caused a dramatic increase in psd95 expression and dendritic spine and synapse formation through sequential activation of the mitogen-activated protein kinase isozymes erk1/2 and protein kinase c (pkc). |
2013-03-04 |
2023-08-12 |
mouse |
| A Mogha, S R Guariglia, P R Debata, G Y Wen, P Banerje. Serotonin 1A receptor-mediated signaling through ERK and PKCα is essential for normal synaptogenesis in neonatal mouse hippocampus. Translational psychiatry. vol 2. 2013-03-04. PMID:22832728. |
finally, compared with the wild type, the 5-ht(1a)-r(-/-) mice harbor significantly less synapses in the hippocampus, but infusion of the pkc-stimulator and alzheimer drug bryostatin into the 5-ht(1a)-r(-/-) mice to bypass the non-existent 5-ht(1a)-r boosted psd95 expression and synaptogenesis. |
2013-03-04 |
2023-08-12 |
mouse |
| A Mogha, S R Guariglia, P R Debata, G Y Wen, P Banerje. Serotonin 1A receptor-mediated signaling through ERK and PKCα is essential for normal synaptogenesis in neonatal mouse hippocampus. Translational psychiatry. vol 2. 2013-03-04. PMID:22832728. |
the elucidated signaling cascade explains how 5-ht(1a)-r regulates hippocampal sculpting and function, which may determine the affective phenotype of an adult. |
2013-03-04 |
2023-08-12 |
mouse |
| Catherine E Hagan, Ross A McDevitt, Yusha Liu, Amy R Furay, John F Neumaie. 5-HT(1B) autoreceptor regulation of serotonin transporter activity in synaptosomes. Synapse (New York, N.Y.). vol 66. issue 12. 2013-02-21. PMID:22961814. |
furthermore, sert activity varies as a function of 5-ht(1b) receptor expression-specifically, genetic deletion of 5-ht(1b) decreased sert function, while viral-mediated overexpression of 5-ht(1b) autoreceptors in rat raphe neurons increased sert activity in rat hippocampal synaptosomes. |
2013-02-21 |
2023-08-12 |
mouse |
| J C Shaw, Ø Øverl. Brain-encysting trematodes and altered monoamine activity in naturally infected killifish Fundulus parvipinnis. Journal of fish biology. vol 81. issue 7. 2013-02-21. PMID:23252735. |
a parasite density-associated decrease in serotonergic activity occurred in the hippocampus of naturally infected fish, as well as a decrease in dopaminergic activity in the raphe nuclei, suggesting that e. californiensis inhibits serotonin and dopamine signaling in naturally infected f. parvipinnis. |
2013-02-21 |
2023-08-12 |
Not clear |
| Sunoh Kwon, Dongsoo Kim, Hyemee Park, Doyoung Yoo, Hi-Joon Park, Dae-Hyun Hahm, Hyejung Lee, Seung-Tae Ki. Prefrontal-limbic change in dopamine turnover by acupuncture in maternally separated rat pups. Neurochemical research. vol 37. issue 10. 2013-02-19. PMID:22714092. |
the present study investigated the possible role of acupuncture in alleviating depression-like behavioral changes and examined changes in the levels of serotonin (5-ht), dopamine (da), and their metabolites in the hippocampus (hp) and prefrontal cortex (pfc) of maternally separated rat pups. |
2013-02-19 |
2023-08-12 |
rat |
| Saida Haider, Saima Khaliq, Saiqa Tabassum, Darakhshan J Halee. Role of somatodendritic and postsynaptic 5-HT₁A receptors on learning and memory functions in rats. Neurochemical research. vol 37. issue 10. 2013-02-19. PMID:22814880. |
among the 5-ht receptors subtypes, 5-ht(1a) receptors are of special interest because these receptors are present in the brain areas involved in learning and memory functions such as hippocampus and cortex. |
2013-02-19 |
2023-08-12 |
rat |
| Hudu G Mikail, Christina Dalla, Nikolaos Kokras, Vasilios Kafetzopoulos, Z Papadopoulou-Daifot. Sertraline behavioral response associates closer and dose-dependently with cortical rather than hippocampal serotonergic activity in the rat forced swim stress. Physiology & behavior. vol 107. issue 2. 2013-02-15. PMID:22771833. |
serotonin and its metabolite 5-hiaa were assayed in the hippocampus and the prefrontal cortex with the use of high-performance liquid chromatography (hplc-ed) and their ratio 5-hiaa/5-ht was calculated. |
2013-02-15 |
2023-08-12 |
rat |
| Hudu G Mikail, Christina Dalla, Nikolaos Kokras, Vasilios Kafetzopoulos, Z Papadopoulou-Daifot. Sertraline behavioral response associates closer and dose-dependently with cortical rather than hippocampal serotonergic activity in the rat forced swim stress. Physiology & behavior. vol 107. issue 2. 2013-02-15. PMID:22771833. |
serotonergic activity was not altered by the 2-day swim stress in either brain region, while subchronic sertraline treatment enhanced 5-ht levels and decreased 5-hiaa/5-ht in the hippocampus and the prefrontal cortex. |
2013-02-15 |
2023-08-12 |
rat |
| Hudu G Mikail, Christina Dalla, Nikolaos Kokras, Vasilios Kafetzopoulos, Z Papadopoulou-Daifot. Sertraline behavioral response associates closer and dose-dependently with cortical rather than hippocampal serotonergic activity in the rat forced swim stress. Physiology & behavior. vol 107. issue 2. 2013-02-15. PMID:22771833. |
in the prefrontal cortex, but not in the hippocampus, immobility duration was negatively correlated with 5-ht tissue levels, whereas swimming duration was positively correlated with 5-ht. |
2013-02-15 |
2023-08-12 |
rat |
| Jia Zhang, Yan Fan, Ying Li, Hobart Zhu, Liang Wang, Meng-Yang Zh. Chronic social defeat up-regulates expression of the serotonin transporter in rat dorsal raphe nucleus and projection regions in a glucocorticoid-dependent manner. Journal of neurochemistry. vol 123. issue 6. 2013-02-14. PMID:23061525. |
protein levels of the serotonin transporter (sert) in the dorsal raphe nucleus (drn), hippocampus, frontal cortex, and amygdala were examined by western blotting or immunofluorescence staining. |
2013-02-14 |
2023-08-12 |
rat |
| A Bacq, L Balasse, G Biala, B Guiard, A M Gardier, A Schinkel, F Louis, V Vialou, M-P Martres, C Chevarin, M Hamon, B Giros, S Gautro. Organic cation transporter 2 controls brain norepinephrine and serotonin clearance and antidepressant response. Molecular psychiatry. vol 17. issue 9. 2013-01-23. PMID:21769100. |
in vivo clearance of ne and 5-ht evaluated using microiontophoretic electrophysiology was diminished in the hippocampus of oct2(-/-) mice in the presence of venlafaxine, thereby affecting postsynaptic neuronal activity. |
2013-01-23 |
2023-08-12 |
mouse |
| Valeria Paola Carlini, María Belén Poretti, Mathias Rask-Andersen, Rohit A Chavan, Marina F Ponzio, Rahul S Sawant, Susana Rubiales de Barioglio, Helgi B Schiöth, Marta Fiol de Cune. Differential effects of fluoxetine and venlafaxine on memory recognition: possible mechanisms of action. Progress in neuro-psychopharmacology & biological psychiatry. vol 38. issue 2. 2013-01-21. PMID:22449479. |
considering that the changes in gene expression involved in the action of antidepressant drugs on memory have not been identified, in this study we investigated the impact of chronic treatment with a ssri (fluoxetine) and a snri (venlafaxine) on the mrna expression of genes related to memory cascade in the mouse hippocampus, namely, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa), nitric oxide synthase 1 (nos1), neurotrophic tyrosine kinase receptor type 2 (trkb), mitogen-activated protein kinases (mapk/erk) and serotonin transporter (sert). |
2013-01-21 |
2023-08-12 |
mouse |