| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ian C Hellstrom, Sabine K Dhir, Josie C Diorio, Michael J Meane. Maternal licking regulates hippocampal glucocorticoid receptor transcription through a thyroid hormone-serotonin-NGFI-A signalling cascade. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 367. issue 1601. 2012-12-06. PMID:22826348. |
in this paper, we report that: (i) the association of ngfi-a with the exon 1(7) gr promoter is dynamically regulated by mother-pup interactions; (ii) this effect is mimicked by artificial tactile stimulation comparable to that provided by pup lg; (iii) that serotonin (5-ht) induces an ngfi-a-dependent increase in gr transcription in hippocampal neurons and ngfi-a overexpression is sufficient for this effect; and (iv) that thyroid hormones and 5-ht are key mediators of the effects of pup lg and tactile stimulation on ngfi-a binding to the exon 1(7) gr promoter in hippocampus. |
2012-12-06 |
2023-08-12 |
rat |
| Ian C Hellstrom, Sabine K Dhir, Josie C Diorio, Michael J Meane. Maternal licking regulates hippocampal glucocorticoid receptor transcription through a thyroid hormone-serotonin-NGFI-A signalling cascade. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 367. issue 1601. 2012-12-06. PMID:22826348. |
these findings suggest that pup lg directly activates 5-ht systems to initiate intracellular signalling pathways in the hippocampus that regulate gr transcription. |
2012-12-06 |
2023-08-12 |
rat |
| Ute Renner, Andre Zeug, Andrew Woehler, Marcus Niebert, Alexander Dityatev, Galina Dityateva, Nataliya Gorinski, Daria Guseva, Dalia Abdel-Galil, Matthias Fröhlich, Frank Döring, Erhard Wischmeyer, Diethelm W Richter, Erwin Neher, Evgeni G Ponimaski. Heterodimerization of serotonin receptors 5-HT1A and 5-HT7 differentially regulates receptor signalling and trafficking. Journal of cell science. vol 125. issue Pt 10. 2012-12-03. PMID:22357950. |
finally, we found that production of 5-ht(7) receptors in the hippocampus continuously decreases during postnatal development, indicating that the relative concentration of 5-ht(1a)-5-ht(7) heterodimers and, consequently, their functional importance undergoes pronounced developmental changes. |
2012-12-03 |
2023-08-12 |
Not clear |
| Francis Rodriguez Bambico, Patrick R Hattan, Jean-Philippe Garant, Gabriella Gobb. Effect of delta-9-tetrahydrocannabinol on behavioral despair and on pre- and postsynaptic serotonergic transmission. Progress in neuro-psychopharmacology & biological psychiatry. vol 38. issue 1. 2012-12-03. PMID:22386778. |
finally, repeated but not single delta-9-thc administration (1mg/kg, ip) enhanced tonic 5-ht(1a) receptor activity in the hippocampus, a postsynaptic event commonly elicited by standard antidepressants. |
2012-12-03 |
2023-08-12 |
rat |
| Francis Rodriguez Bambico, Patrick R Hattan, Jean-Philippe Garant, Gabriella Gobb. Effect of delta-9-tetrahydrocannabinol on behavioral despair and on pre- and postsynaptic serotonergic transmission. Progress in neuro-psychopharmacology & biological psychiatry. vol 38. issue 1. 2012-12-03. PMID:22386778. |
these results suggest that delta-9-thc, like other cb(1)r agonists and endocannabinoid enhancers, may possess antidepressant properties at low doses, and could modulate 5-ht transmission in the dr and hippocampus as standard antidepressants such as selective serotonin reuptake inhibitors. |
2012-12-03 |
2023-08-12 |
rat |
| G Ulrich-Merzenich, O Kelber, A Koptina, A Freischmidt, J Heilmann, J Müller, H Zeitler, M F Seidel, M Ludwig, E U Heinrich, H Winterhof. Novel neurological and immunological targets for salicylate-based phytopharmaceuticals and for the anti-depressant imipramine. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 19. issue 10. 2012-12-03. PMID:22743246. |
in addition, the hippocampus of rats treated (27 d) with wb (15-60 mg/kg wb) or imipramine (15 mg/kg bw) showed a slower serotonin turnover (5-hydroxyindol acetic acid/serotonin (p<0.05)) depending on the dosage. |
2012-12-03 |
2023-08-12 |
rat |
| Daniela M Pechlivanova, Jana D Tchekalarova, Liana H Alova, Vesselin V Petkov, Rumen P Nikolov, Krassimira S Yakimov. Effect of long-term caffeine administration on depressive-like behavior in rats exposed to chronic unpredictable stress. Behavioural pharmacology. vol 23. issue 4. 2012-12-03. PMID:22785384. |
in cus-exposed rats, caffeine showed antidepressant and anxiolytic activity, accompanied by increased hippocampal dopamine and serotonin levels. |
2012-12-03 |
2023-08-12 |
rat |
| Katherine M Nautiyal, Christopher A Dailey, Jaquelyn L Jahn, Elizabeth Rodriquez, Nguyen Hong Son, Jonathan V Sweedler, Rae Silve. Serotonin of mast cell origin contributes to hippocampal function. The European journal of neuroscience. vol 36. issue 3. 2012-11-30. PMID:22632453. |
serotonin of mast cell origin contributes to hippocampal function. |
2012-11-30 |
2023-08-12 |
mouse |
| Katherine M Nautiyal, Christopher A Dailey, Jaquelyn L Jahn, Elizabeth Rodriquez, Nguyen Hong Son, Jonathan V Sweedler, Rae Silve. Serotonin of mast cell origin contributes to hippocampal function. The European journal of neuroscience. vol 36. issue 3. 2012-11-30. PMID:22632453. |
measurements based on capillary electrophoresis with native fluorescence detection indicate that a significant contribution of serotonin to the hippocampal milieu is associated with mast cell activation. |
2012-11-30 |
2023-08-12 |
mouse |
| Katherine M Nautiyal, Christopher A Dailey, Jaquelyn L Jahn, Elizabeth Rodriquez, Nguyen Hong Son, Jonathan V Sweedler, Rae Silve. Serotonin of mast cell origin contributes to hippocampal function. The European journal of neuroscience. vol 36. issue 3. 2012-11-30. PMID:22632453. |
chronic treatment with fluoxetine, a selective serotonin reuptake inhibitor, reverses the deficit in hippocampal neurogenesis in mast cell-deficient mice. |
2012-11-30 |
2023-08-12 |
mouse |
| F M Farias, C S Passos, M D Arbo, D M Barros, C Gottfried, V M Steffen, A T Henrique. Strictosidinic acid, isolated from Psychotria myriantha Mull. Arg. (Rubiaceae), decreases serotonin levels in rat hippocampus. Fitoterapia. vol 83. issue 6. 2012-11-29. PMID:22546150. |
(rubiaceae), decreases serotonin levels in rat hippocampus. |
2012-11-29 |
2023-08-12 |
rat |
| F M Farias, C S Passos, M D Arbo, D M Barros, C Gottfried, V M Steffen, A T Henrique. Strictosidinic acid, isolated from Psychotria myriantha Mull. Arg. (Rubiaceae), decreases serotonin levels in rat hippocampus. Fitoterapia. vol 83. issue 6. 2012-11-29. PMID:22546150. |
the results indicate that strictosidinic acid seems to act on 5-ht system in rat hippocampus, possibly inhibiting precursor enzymes of 5-ht biosynthesis. |
2012-11-29 |
2023-08-12 |
rat |
| Krzysztof Tokarski, Agnieszka Zelek-Molik, Beata Duszyńska, Grzegorz Satała, Bartosz Bobula, Magdalena Kusek, Piotr Chmielarz, Irena Nalepa, Grzegorz Hes. Acute and repeated treatment with the 5-HT7 receptor antagonist SB 269970 induces functional desensitization of 5-HT7 receptors in rat hippocampus. Pharmacological reports : PR. vol 64. issue 2. 2012-11-23. PMID:22661174. |
the present work was aimed at examining the effect of single and repeated (14 days) administration of sb 269970 on the 5-ht(7) receptor in the hippocampus. |
2012-11-23 |
2023-08-12 |
rat |
| Jenny Molet, Elodie Bouaziz, Michel Hamon, Laurence Lanfume. Early exposure to ethanol differentially affects ethanol preference at adult age in two inbred mouse strains. Neuropharmacology. vol 63. issue 2. 2012-11-19. PMID:22521807. |
in contrast, early ethanol ingestion by c57bl/6j mice transiently lowered spontaneous ethanol consumption and increased g protein coupling of postsynaptic 5-ht(1a) receptors in the hippocampus but had no effect on cb1 receptors at adulthood. |
2012-11-19 |
2023-08-12 |
mouse |
| Masatoshi Nagano, Mingyan Liu, Hirofumi Inagaki, Tomoyuki Kawada, Hidenori Suzuk. Early intervention with fluoxetine reverses abnormalities in the serotonergic system and behavior of rats exposed prenatally to dexamethasone. Neuropharmacology. vol 63. issue 2. 2012-11-19. PMID:22710353. |
in the present study, we found abnormalities in serotonin (5-ht) signaling, including decreased expression of 5-ht(1a) receptor (5-ht(1a)-r) mrna in the medial prefrontal cortex (mpfc) and 5-ht content in the hippocampus at postnatal week (pw) 4. |
2012-11-19 |
2023-08-12 |
rat |
| Masatoshi Nagano, Mingyan Liu, Hirofumi Inagaki, Tomoyuki Kawada, Hidenori Suzuk. Early intervention with fluoxetine reverses abnormalities in the serotonergic system and behavior of rats exposed prenatally to dexamethasone. Neuropharmacology. vol 63. issue 2. 2012-11-19. PMID:22710353. |
likewise, flx increased 5-ht concentrations in the mpfc and ventral hippocampus at pw3 and normalized 5-ht(1a)-r mrna concentrations in the mpfc at pw4. |
2012-11-19 |
2023-08-12 |
rat |
| K L Eskow Jaunarajs, J A George, C Bisho. L-DOPA-induced dysregulation of extrastriatal dopamine and serotonin and affective symptoms in a bilateral rat model of Parkinson's disease. Neuroscience. vol 218. 2012-11-16. PMID:22659568. |
in the first experiment, striatal, hippocampal, amygdalar, and prefrontal cortex da and 5-ht levels were examined at various post-treatment time-points. |
2012-11-16 |
2023-08-12 |
rat |
| Daphne Everaerd, Lotte Gerritsen, Mark Rijpkema, Thomas Frodl, Iris van Oostrom, Barbara Franke, Guillén Fernández, Indira Tendolka. Sex modulates the interactive effect of the serotonin transporter gene polymorphism and childhood adversity on hippocampal volume. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 8. 2012-11-13. PMID:22434222. |
sex modulates the interactive effect of the serotonin transporter gene polymorphism and childhood adversity on hippocampal volume. |
2012-11-13 |
2023-08-12 |
Not clear |
| Heidi Kaastrup Müller, Gregers Wegener, Betina Elfvin. Chronic restraint stress affects serotonin transporter uptake kinetics but not binding sites in the rat hippocampus. Synapse (New York, N.Y.). vol 66. issue 3. 2012-11-09. PMID:21954049. |
chronic restraint stress affects serotonin transporter uptake kinetics but not binding sites in the rat hippocampus. |
2012-11-09 |
2023-08-12 |
rat |
| Elena M Kondaurova, Vladimir S Naumenko, Nina K Popov. Effect of chronic activation of 5-HT3 receptors on 5-HT3, 5-HT(1A) and 5-HT(2A) receptors functional activity and expression of key genes of the brain serotonin system. Neuroscience letters. vol 522. issue 1. 2012-11-09. PMID:22705909. |
chronic activation of 5-ht(3) receptor produced no considerable effect on the expression on 5-ht(3), 5-ht(1a), and 5-ht transporter (5-htt) and tryptophan hydroxylase-2 (tph-2) genes - the key genes of brain 5-ht system, in the midbrain, frontal cortex and hippocampus. |
2012-11-09 |
2023-08-12 |
mouse |