| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Azmitia, M J Brennan, D Quartermai. Adult development of the hippocampal-serotonin system of C57BL/6N mice; analysis of high-affinity uptake of (3)H-5HT in slices and synaptosomes. Neurochemistry international. vol 5. issue 1. 2012-10-02. PMID:20487920. |
kinetic analysis of the [(3)h]5ht high-affinity uptake in the hippocampus (3 min, 37 degrees c) revealed the same apparent k(m) for serotonin at both ages (6.7 x 10(?8) m), but a 44% decrease in v(max) in the aged hippocampal synaptosomal high-affinity uptake compared to adults (120 vs 215 pmol of 5-ht/g-tissue/3 min). |
2012-10-02 |
2023-08-12 |
mouse |
| C Goetz, S Bourgoin, F Cesselin, A Brandi, D Bression, M Martinet, F Peillon, M Hamo. Alterations in central neurotransmitter receptor binding sites following estradiol implantation in female rats. Neurochemistry international. vol 5. issue 4. 2012-10-02. PMID:20487964. |
examination of neurotransmitter receptors in the hippocampus, striatum and cerebral cortex one month after the implantation revealed that estrogenization was associated with: an increased density of (3)h-domperidone binding sites (d(2) receptors) in the striatum and reduced numbers of (3)h-serotonin high affinity sites (5-ht(1) receptors) in the hippocampus and of (3)h-muscimol binding sites (gaba receptors) in the hippocampus, striatum and cerebral cortex. |
2012-10-02 |
2023-08-12 |
rat |
| M C Boadle-Biber, J N Johannessen, N Narasimhachari, T H Pha. Tryptophan hydroxylase: increase in activity by electrical stimulation of serotonergic neurons. Neurochemistry international. vol 8. issue 1. 2012-10-02. PMID:20493033. |
in contrast, activity of enzyme from hippocampus, which receives its 5-ht innervation primarily from the median raphe was unaffected by dorsal raphe stimulation. |
2012-10-02 |
2023-08-12 |
rat |
| P E Potter, L G Harsing, I Kakucska, G Gaal, E S Viz. Selective impairment of acetylcholine release and content in the central nervous system following intracerebroventricular administration of ethylcholine mustard aziridinium ion (AF64A) in the rat. Neurochemistry international. vol 8. issue 2. 2012-10-02. PMID:20493047. |
non-specific changes in hippocampal levels of dopamine, noradrenaline and 5-hydroxytryptamine were also observed. |
2012-10-02 |
2023-08-12 |
rat |
| P E Potter, L G Harsing, I Kakucska, G Gaal, E S Viz. Selective impairment of acetylcholine release and content in the central nervous system following intracerebroventricular administration of ethylcholine mustard aziridinium ion (AF64A) in the rat. Neurochemistry international. vol 8. issue 2. 2012-10-02. PMID:20493047. |
although there was a transient reduction in hippocampal 5-hydroxytryptamine content 4 days after treatment, this had recovered to control levels within 7 days. |
2012-10-02 |
2023-08-12 |
rat |
| A J Cross, G P Reynolds, L M Hewitt, P Slate. Brain serotonin receptors in Huntington's disease. Neurochemistry international. vol 9. issue 3. 2012-10-02. PMID:20493143. |
significant reductions in serotonin s1 receptors were observed in putamen and hippocampus but not in frontal and temporal cortices. |
2012-10-02 |
2023-08-12 |
Not clear |
| L Kiedrowski, M Gra Dkowska, B Oderfeld-Nowa. Time dependent effect of GM, ganglioside administration upon [(3)H]5-hydroxytryptamine uptake in partially denervated rat hippocampus. Neurochemistry international. vol 10. issue 2. 2012-10-02. PMID:20501070. |
time dependent effect of gm, ganglioside administration upon [(3)h]5-hydroxytryptamine uptake in partially denervated rat hippocampus. |
2012-10-02 |
2023-08-12 |
rat |
| L Kiedrowski, M Gra Dkowska, B Oderfeld-Nowa. Time dependent effect of GM, ganglioside administration upon [(3)H]5-hydroxytryptamine uptake in partially denervated rat hippocampus. Neurochemistry international. vol 10. issue 2. 2012-10-02. PMID:20501070. |
this effect was limited to the most denervated dorsal hippocampal part, where the lesion-evoked decrease of [(3)h]5-hydroxytryptamine uptake was the strongest. |
2012-10-02 |
2023-08-12 |
rat |
| L Kiedrowski, M Gra Dkowska, B Oderfeld-Nowa. Time dependent effect of GM, ganglioside administration upon [(3)H]5-hydroxytryptamine uptake in partially denervated rat hippocampus. Neurochemistry international. vol 10. issue 2. 2012-10-02. PMID:20501070. |
on the other hand, prolonged gm(1) administration (21-90 days) to unoperated animals caused a small but significant reduction of [(3)h]5-hydroxytryptamine uptake, equal in all three hippocampal parts. |
2012-10-02 |
2023-08-12 |
rat |
| R P Smits, H W Steinbusch, A H Mulde. Studies on the specificity of uptake and release of radiolabelled histamine in rat brain slices. Neurochemistry international. vol 12. issue 2. 2012-10-02. PMID:20501221. |
thus 6-hydroxydopamine- and 5,7-dihydroxytryptamine-induced lesions not only reduced the uptake of [(3)h]dopamine (in striatal slices) and [(3)h]serotonin (in hippocampal slices), but also, though to a lesser extent, that of [(3)h]histamine. |
2012-10-02 |
2023-08-12 |
human |
| A B Norman, D R Nash, P R Sanber. [(3)H]lysergic acid diethylamide (LSD): differential agonist and antagonist binding properties at 5-HT receptor subtypes in rat brain. Neurochemistry international. vol 14. issue 4. 2012-10-02. PMID:20504456. |
[(3)h]lysergic acid diethylamide (lsd) in the presence of 40 nm ketanserin labeled the 5-ht(1a) receptor subtype in rat hippocampal membranes. |
2012-10-02 |
2023-08-12 |
rat |
| Q Pei, T Zetterström, M Fillen. Measurement of extracellular 5-HT and 5-HIAA in hippocampus of freely moving rats using microdialysis: long-term applications. Neurochemistry international. vol 15. issue 4. 2012-10-02. PMID:20504526. |
measurement of extracellular 5-ht and 5-hiaa in hippocampus of freely moving rats using microdialysis: long-term applications. |
2012-10-02 |
2023-08-12 |
rat |
| Q Pei, T Zetterström, M Fillen. Measurement of extracellular 5-HT and 5-HIAA in hippocampus of freely moving rats using microdialysis: long-term applications. Neurochemistry international. vol 15. issue 4. 2012-10-02. PMID:20504526. |
extracellular levels of 5-hydroxytryptamine (5-ht) and its metabolite 5-hydroxyindoleacetic acid (5-hiaa) were measured in the ventral hippocampus of the awake rat using microdialysis. |
2012-10-02 |
2023-08-12 |
rat |
| Q Pei, T Zetterström, M Fillen. Measurement of extracellular 5-HT and 5-HIAA in hippocampus of freely moving rats using microdialysis: long-term applications. Neurochemistry international. vol 15. issue 4. 2012-10-02. PMID:20504526. |
the basal level of 5-ht in hippocampal dialysates was very close to the detection limit of our assay. |
2012-10-02 |
2023-08-12 |
rat |
| Q Pei, T Zetterström, M Fillen. Measurement of extracellular 5-HT and 5-HIAA in hippocampus of freely moving rats using microdialysis: long-term applications. Neurochemistry international. vol 15. issue 4. 2012-10-02. PMID:20504526. |
these results suggest that in the presence of citalopram, 5-ht in hippocampal dialysates is derived from serotonergic neurones. |
2012-10-02 |
2023-08-12 |
rat |
| F P Zemlan, A Zieleniewski-Murphy, R Maureen Murphy, M M Behbehan. BMY 7378: Partial agonist at spinal cord 5-HT(1A) receptors. Neurochemistry international. vol 16. issue 4. 2012-10-02. PMID:20504590. |
recent data indicate that bmy 7378 demonstrates high affinity, selectivity and low intrinsic activity at hippocampal 5-ht(1a) receptors, suggesting that bmy 7378 may represent the first selective 5-ht(1a) functional antagonist. |
2012-10-02 |
2023-08-12 |
rat |
| F P Zemlan, A Zieleniewski-Murphy, R Maureen Murphy, M M Behbehan. BMY 7378: Partial agonist at spinal cord 5-HT(1A) receptors. Neurochemistry international. vol 16. issue 4. 2012-10-02. PMID:20504590. |
differences in bmy 7378 intrinsic activity at spinal cord as opposed to hippocampal 5-ht(1a) receptors are discussed in terms of regional differences in g-proteins coupled to 5-ht(1a) receptors in these two cns regions. |
2012-10-02 |
2023-08-12 |
rat |
| G Schulze, H Coper, C Fähndric. Adaptation capacity of biogenic amines turnover to hypoxia in different brain areas of old rats. Neurochemistry international. vol 17. issue 2. 2012-10-02. PMID:20504628. |
in order to contribute findings which might help to understand differences in functioning and behavioral performances with aging, the concentrations of dopa, dopamine, noradrenaline, 5-hydroxytryptophane (5-htp), 5-hydroxytryptamine (5-ht), 5-hydroxyindoleacetic acid (5-hiaa) in four brain regions (hypothalamus, c. striatum, hippocampus, cortex) of young and old rats were determined 30 min after i.p. |
2012-10-02 |
2023-08-12 |
rat |
| P Janssens de Varebeke, E Schallauer, W D Rausch, P Riederer, M B Youdi. Milacemide, the selective substrate and enzyme-activated specific inhibitor of monoamine oxidase B, increases dopamine but not serotonin in caudate nucleus of rhesus monkey. Neurochemistry international. vol 17. issue 2. 2012-10-02. PMID:20504633. |
although serotonin (5-ht) and its oxidatively deaminated metabolite, 5-hydroxyindoleacetic acid (5-hiaa) in the striatum, pons and hippocampus were unchanged, significant increases in frontal cortex, temporal cortex and visual cortex 5-ht were noted. |
2012-10-02 |
2023-08-12 |
human |
| María Teresa Antonio, Victoria Peinado, José Carlos González, María Luisa Lere. Effects of maternal cadmium administration on development of monoaminergic, GABAergic and glutamatergic systems. Environmental toxicology and pharmacology. vol 29. issue 1. 2012-10-02. PMID:21787587. |
hippocampal levels of serotonin and 5-hydroxyindolacetic acid were significantly reduced in rats exposed to cd whereas the dopamine content was not significantly affected by cd. |
2012-10-02 |
2023-08-12 |
rat |