| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying-pan Zhao, Min Su, Feng-yun Wang, Zhao-xiang Bian, Jian-qin Yang, Wei Wang, Xu-dong Tan. [Effect of Chang'an No. I Recipe on 5-hydroxytryptamine Signal System and mRNA Expression Levels of Hippocampal Brain Derived Neurotrophic Factor in Visceral Hypersensitivity Rats with Irritable Bowel Syndrome]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine vol 35 issue 10 2016 26677676 |
i recipe (ca) on 5-hydroxytryptamine signal system and mrna expression levels of hippocampal brain derived neurotrophic factor (bdnf) in visceral hypersensitivity model rats with irritable bowel syndrome (ibs). |
2016-09-15 |
2022-01-12 |
Not clear |
| Giuseppe Musumeci, Paola Castrogiovanni, Sergio Castorina, Rosa Imbesi, Marta Anna Szychlinska, Soraya Scuderi, Carla Loreto, Salvatore Giunt. Changes in serotonin (5-HT) and brain-derived neurotrophic factor (BDFN) expression in frontal cortex and hippocampus of aged rat treated with high tryptophan diet. Brain research bulletin vol 119 issue Pt A 2016 26444078 |
interestingly, immunohistochemical analyses confirmed that high trp diet significantly elevates the number of 5-ht immunoreactive fibers in both brain areas tested and this correlated with bdnf increase in the fc and hippocampal regions ca1, ca2, ca3 and a strikingly down-regulation of neurotrophin levels in the dentate gyrus (dg) of aged rats. |
2016-08-29 |
2022-01-12 |
Not clear |
| J Tchekalarova, M Shishmanova, D Atanasova, M Stefanova, L Alova, N Lazarov, K Georgiev. Effect of endurance training on seizure susceptibility, behavioral changes and neuronal damage after kainate-induced status epilepticus in spontaneously hypertensive rats. Brain research vol 1625 issue 2016 26319691 |
our results indicate that prior exercise is an effective means to attenuate ka-induced seizures and comorbid behavioral changes in a model of hypertension and epilepsy suggesting a potential influence of hippocampal 5-ht on a comorbid depression. |
2016-08-15 |
2022-01-12 |
Not clear |
| S Liang, T Wang, X Hu, J Luo, W Li, X Wu, Y Duan, F Ji. Administration of Lactobacillus helveticus NS8 improves behavioral, cognitive, and biochemical aberrations caused by chronic restraint stress. Neuroscience vol 310 issue 2016 26408987 |
l. helveticus ns8 also resulted in lower plasma corticosterone (cort) and adrenocorticotropic hormone (acth) levels, higher plasma interleukin-10 (il-10) levels, restored hippocampal serotonin (5-ht) and norepinephrine (ne) levels, and more hippocampal brain-derived neurotrophic factor (bdnf) mrna expression than in chronic stress rats. |
2016-08-15 |
2022-01-12 |
Not clear |
| M Kondo, Y Nakamura, Y Ishida, S Shimad. The 5-HT3 receptor is essential for exercise-induced hippocampal neurogenesis and antidepressant effects. Molecular psychiatry vol 20 issue 11 2016 25403840 |
in this study, analysis of the 5-ht type 3a receptor subunit-deficient (htr3a(-/-)) mice revealed that lack of the 5-ht type 3 (5-ht3) receptor resulted in loss of exercise-induced hippocampal neurogenesis and antidepressant effects, but not of learning enhancement. |
2016-08-02 |
2022-01-12 |
Not clear |
| M Kondo, Y Nakamura, Y Ishida, S Shimad. The 5-HT3 receptor is essential for exercise-induced hippocampal neurogenesis and antidepressant effects. Molecular psychiatry vol 20 issue 11 2016 25403840 |
these findings demonstrate that the 5-ht3 receptor is the critical target of 5-ht action in the brain following exercise, and is indispensable for hippocampal neurogenesis and antidepressant effects induced by exercise. |
2016-08-02 |
2022-01-12 |
Not clear |
| Elena Dale, Alan L Pehrson, Theepica Jeyarajah, Yan Li, Steven C Leiser, Gennady Smagin, Christina K Olsen, Connie Sanche. Effects of serotonin in the hippocampus: how SSRIs and multimodal antidepressants might regulate pyramidal cell function. CNS spectrums vol 21 issue 2 2016 26346726 |
extensive preclinical research and the notion that modulation of serotonin (5-ht) neurotransmission plays a key role in the therapeutic efficacy of selective serotonin reuptake inhibitors (ssris) support the view that 5-ht is important for hippocampal function in normal and disease-like conditions. |
2016-07-19 |
2022-01-12 |
Not clear |
| Elena Dale, Alan L Pehrson, Theepica Jeyarajah, Yan Li, Steven C Leiser, Gennady Smagin, Christina K Olsen, Connie Sanche. Effects of serotonin in the hippocampus: how SSRIs and multimodal antidepressants might regulate pyramidal cell function. CNS spectrums vol 21 issue 2 2016 26346726 |
furthermore, hippocampal cells often co-express multiple 5-ht receptor subtypes that can have either complementary or opposing effects on cell function, adding to the complexity of 5-ht neurotransmission. |
2016-07-19 |
2022-01-12 |
Not clear |
| Elena Dale, Alan L Pehrson, Theepica Jeyarajah, Yan Li, Steven C Leiser, Gennady Smagin, Christina K Olsen, Connie Sanche. Effects of serotonin in the hippocampus: how SSRIs and multimodal antidepressants might regulate pyramidal cell function. CNS spectrums vol 21 issue 2 2016 26346726 |
here we review the current knowledge of how 5-ht, through its various receptor subtypes, modulates hippocampal output and the activity of hippocampal pyramidal cells in rodents. |
2016-07-19 |
2022-01-12 |
Not clear |
| Claudia B\\xc3\\xb6hm, Maria Pangalos, Dietmar Schmitz, Jochen Wintere. Serotonin Attenuates Feedback Excitation onto O-LM Interneurons. Cerebral cortex (New York, N.Y. : 1991) vol 25 issue 11 2016 26021702 |
here, we focus on the neuromodulatory effects of 5-ht on gabaergic inhibitory oriens lacunosum-moleculare (o-lm) cells in the hippocampal area ca1 of the rat. |
2016-07-18 |
2022-01-12 |
Not clear |
| Jing-jing Le, Tao Yi, Li Qi, Ji Li, Lei Shao, Jing-cheng Don. Electroacupuncture regulate hypothalamic-pituitary-adrenal axis and enhance hippocampal serotonin system in a rat model of depression. Neuroscience letters vol 615 issue 2016 26773866 |
dysfunction of the hippocampal serotonin (5-hydroxytryptamine, 5-ht) system has been shown to be a key factor in depression. |
2016-07-14 |
2022-01-12 |
Not clear |
| Russell A Morton, C Fernando Valenzuel. Third Trimester Equivalent Alcohol Exposure Reduces Modulation of Glutamatergic Synaptic Transmission by 5-HT1A Receptors in the Rat Hippocampal CA3 Region. Frontiers in neuroscience vol 10 issue 2016 27375424 |
the objective of this study was to identify the effects of third trimester ethanol (etoh) exposure on hippocampal 5-ht signaling. |
2016-07-04 |
2022-01-12 |
Not clear |
| Carla Letizia Busceti, Paola Di Pietro, Barbara Riozzi, Anna Traficante, Francesca Biagioni, Robert Nistic\\xc3\\xb2, Francesco Fornai, Giuseppe Battaglia, Ferdinando Nicoletti, Valeria Brun. 5-HT(2C) serotonin receptor blockade prevents tau protein hyperphosphorylation and corrects the defect in hippocampal synaptic plasticity caused by a combination of environmental stressors in mice. Pharmacological research vol 99 issue 2016 26145279 |
5-ht(2c) serotonin receptor blockade prevents tau protein hyperphosphorylation and corrects the defect in hippocampal synaptic plasticity caused by a combination of environmental stressors in mice. |
2016-06-13 |
2022-01-12 |
Not clear |
| Xiaoxia Zhu, Linlin Jing, Chun Chen, Meng Shao, Qin Fan, Jianxin Diao, Yuanliang Liu, Zhiping Lv, Xuegang Su. Danzhi Xiaoyao San ameliorates depressive-like behavior by shifting toward serotonin via the downregulation of hippocampal indoleamine 2,3-dioxygenase. Journal of ethnopharmacology vol 160 issue 2016 25435286 |
this study is aimed to investigate the hypothesis that dxs treats depressive-like behavior by shifting the balance of the kynurenine (kyn)/serotonin (5-ht) pathway toward the 5-ht pathway through the downregulation of hippocampal indoleamine 2,3-dioxygenase (ido). |
2016-05-23 |
2022-01-12 |
Not clear |
| Bruno Carabelli, Ana Marcia Delattre, Claudia Pudell, Marco Aur\\xc3\\xa9lio Mori, Deborah Suchecki, Ricardo B Machado, Daniel Paulino Venancio, S\\xc3\\xadlvia Regina Piazzetta, Ivilim Hammerschmidt, S\\xc3\\xadlvio M Zanata, Marcelo M S Lima, Jana\\xc3\\xadna Menezes Zanoveli, Anete Curte Ferra. The Antidepressant-Like Effect of Fish Oil: Possible Role of Ventral Hippocampal 5-HT1A Post-synaptic Receptor. Molecular neurobiology vol 52 issue 1 2016 25139282 |
fish oil-supplemented offspring displayed less depressive-like behaviors in the mfst reflected by decreased immobility and increased swimming and higher 5-ht hippocampal levels. |
2016-05-17 |
2022-01-12 |
Not clear |
| R M Santiago, F S Tonin, J Barbiero, T Zaminelli, S L Boschen, R Andreatini, C Da Cunha, M M S Lima, M A B F Vita. The nonsteroidal antiinflammatory drug piroxicam reverses the onset of depressive-like behavior in 6-OHDA animal model of Parkinson's disease. Neuroscience vol 300 issue 2016 25999296 |
in conclusion, 21-day treatment with piroxicam reversed the onset of depressive-like behavior and prevented the reduction of hippocampal 5-ht levels. |
2016-03-29 |
2022-01-12 |
Not clear |
| C Norman. Towards a new model for cellular pathophysiology in affective disorder. Acta neuropsychiatrica vol 12 issue 3 2016 26975257 |
we tested the modulation of hippocampal long-term plasticity, a model for learning and memory, by 5-ht and found a selective impairment of long-term depression resulting in a positive modification of synaptic network properties. |
2016-03-16 |
2022-01-12 |
Not clear |
| Lingpeng Zhu, Tingting Wei, Jing Gao, Xiayun Chang, He He, Mingxing Miao, Tianhua Ya. Salidroside attenuates lipopolysaccharide (LPS) induced serum cytokines and depressive-like behavior in mice. Neuroscience letters vol 606 issue 2016 26300543 |
levels of neurotransmitters like norepinephrine (ne) and 5-hydroxytryptamine (5-ht) in the prefrontal cortex were detected by hplc-ms. further, brain-derived neurotrophic factor (bdnf), tropomyosin-related kinase b (trkb) and nuclear factor-\xce\xbab (nf-\xce\xbab) in hippocampal was determined by western blot analysis. |
2016-03-01 |
2022-01-12 |
Not clear |
| C B\\xc3\\xa9try, D Overstreet, N Haddjeri, A L Pehrson, C Bundgaard, C Sanchez, A M\\xc3\\xb8r. A 5-HT3 receptor antagonist potentiates the behavioral, neurochemical and electrophysiological actions of an SSRI antidepressant. Pharmacology, biochemistry, and behavior vol 131 issue 2016 25697477 |
it partially prevented the suppressant effect of paroxetine on drn 5-ht neuronal firing and enhanced the paroxetine-induced increase of hippocampal extracellular 5-ht release. |
2016-01-15 |
2022-01-12 |
Not clear |
| Momen W Alhaj, Sawsan A Zaitone, Yasser M Moustaf. Fluvoxamine alleviates seizure activity and downregulates hippocampal GAP-43 expression in pentylenetetrazole-kindled mice: role of 5-HT3 receptors. Behavioural pharmacology vol 26 issue 4 2016 25590967 |
repeated administration of fluvoxamine (20\xe2\x80\x89mg/kg) in ptz-kindled mice suppressed seizure scores, protected against hippocampal neuronal loss, and downregulated gap-43 expression, without producing any signs of the 5-ht syndrome in healthy rats. |
2016-01-13 |
2022-01-12 |
Not clear |