| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chang Ye, Tianci Zhou, Ying Deng, Shuai Wu, Tianyu Zeng, Jie Yang, Yun Stone Shi, Yongmei Yin, Genxi L. Enhanced performance of enzymes confined in biocatalytic hydrogen-bonded organic frameworks for sensing of glutamate in the central nervous system. Biosensors & bioelectronics. vol 247. 2023-12-26. PMID:38147717. |
in this work, we propose the first example of using biocatalytic hydrogen-bonded organic frameworks (hofs) as the hosting matrix to encapsulate glutamate oxidase (glod) via a de novo approach, fabricating a cascaded-enzyme nanoreactor for glu biosensing. |
2023-12-26 |
2023-12-29 |
mouse |
| Robert Hitzemann, Angela R Ozburn, Denesa Lockwood, Tamara J Phillip. Modeling Brain Gene Expression in Alcohol Use Disorder with Genetic Animal Models. Current topics in behavioral neurosciences. 2023-11-20. PMID:37982929. |
both the animal and human data point to the importance for aud of changes in synaptic transmission (particularly glutamate and gaba transmission), of changes in the extracellular matrix (specifically including collagens, cadherins and protocadherins) and of changes in neuroimmune processes. |
2023-11-20 |
2023-11-29 |
human |
| Ying Huang, Zhenzhen Wang, Zhi-Xin Huang, Zhenguo Li. Biomarkers and the outcomes of ischemic stroke. Frontiers in molecular neuroscience. vol 16. 2023-06-21. PMID:37342100. |
in this review, we summarized the data on a number of important biomarkers including glutamate, s100b, glial fibrillary acidic protein, receptor for advanced glycation end-products, intercellular adhesion molecule-1, von willebrand factor, matrix metalloproteinase-9, interleukin-6, tumor necrosis factor-a, activated protein c, copeptin, neuron-specific enolase, tau protein, gamma aminobutyric acid, blood glucose, endothelial progenitor cells, and circulating cd34-positive cells that could be potentially used to indicate the disease burden and/or predict clinical outcome of ischemic stroke. |
2023-06-21 |
2023-08-14 |
Not clear |
| Chloe Delepine, Jennifer Shih, Keji Li, Pierre Gaudeaux, Mriganka Su. Differential effects of astrocyte manipulations on learned motor behavior and neuronal ensembles in the motor cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-03-09. PMID:36894315. |
rna sequencing further supports a role for m1 astrocytes in motor learning and shows changes in astrocytic expression of glutamate transporter genes, gaba transporter genes, and extracellular matrix protein genes in mice that have acquired this learned behavior. |
2023-03-09 |
2023-08-14 |
mouse |
| José Javier Miguel-Hidalg. Astrocytes as Context for the Involvement of Myelin and Nodes of Ranvier in the Pathophysiology of Depression and Stress-Related Disorders. Journal of psychiatry and brain science. vol 8. 2023-03-03. PMID:36866235. |
some of these changes involve the expression of connexins supporting astrocyte-to-oligodendrocyte gap junctions, extracellular matrix components produced by astrocytes around nodes of ranvier, specific types of astrocyte glutamate transporters, and neurotrophic factors secreted by astrocytes that are involved in the development and plasticity of myelin. |
2023-03-03 |
2023-08-14 |
human |
| Vishal Patel, Amit Joharapurkar, Mukul Jai. Therapeutic Potential of Diacerein in Management of Pain. Current drug research reviews. vol 14. issue 3. 2022-10-25. PMID:36281831. |
the effect of diacerein and rhein on mediators of pain, such as transient receptor potential cation channel subfamily v (trpv1), substance p, glutamate, inflammatory cytokines, nitric oxide, matrix metalloproteinases, histamine, palmitoylethanolamide, nuclear factor-kappa b (nfkb), and prostaglandin, has also been discussed. |
2022-10-25 |
2023-08-14 |
Not clear |
| Tessa H de Bie, Michiel G J Balvers, Ric C H de Vos, Renger F Witkamp, Maarten A Jongsm. The influence of a tomato food matrix on the bioavailability and plasma kinetics of oral gamma-aminobutyric acid (GABA) and its precursor glutamate in healthy men. Food & function. 2022-07-19. PMID:35852458. |
the influence of a tomato food matrix on the bioavailability and plasma kinetics of oral gamma-aminobutyric acid (gaba) and its precursor glutamate in healthy men. |
2022-07-19 |
2023-08-14 |
Not clear |
| Sotiria Tavoulari, Denis Lacabanne, Chancievan Thangaratnarajah, Edmund R S Kunj. Pathogenic variants of the mitochondrial aspartate/glutamate carrier causing citrin deficiency. Trends in endocrinology and metabolism: TEM. 2022-06-20. PMID:35725541. |
the cause is the absence or dysfunction of the calcium-regulated mitochondrial aspartate/glutamate carrier 2 (agc2/slc25a13), also called citrin, which imports glutamate into the mitochondrial matrix and exports aspartate to the cytosol. |
2022-06-20 |
2023-08-14 |
Not clear |
| Weam W Ibrahim, Rabab H Sayed, Esraa A Kandil, Walaa Wadi. Niacin mitigates blood-brain barrier tight junctional proteins dysregulation and cerebral inflammation in ketamine rat model of psychosis: Role of GPR109A receptor. Progress in neuro-psychopharmacology & biological psychiatry. 2022-06-11. PMID:35690118. |
niacin significantly ameliorated ketamine-induced behavioral deficits, amended gamma aminobutyric acid and glutamate concentration, decreased tumor necrosis factor-α and matrix metallopeptidase 9 levels, and increased netrin-1 contents in the hippocampus of rats. |
2022-06-11 |
2023-08-14 |
rat |
| Richard M Danilkowicz, Selene G Parekh, David M Tainter, Nicholas Allen, Jeffrey O'Donnell, Andrew Hanselman, Samuel B Adam. Histologic grading correlates with inflammatory biomarkers in tibialis posterior tendon dysfunction. Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons. 2022-06-06. PMID:35667952. |
the purpose of this study was to determine if inflammatory cytokines, matrix metalloproteases (mmps), and glutamate were elevated in diseased tibialis posterior tendons (tpts). |
2022-06-06 |
2023-08-14 |
Not clear |
| Y Whulanza, Y B Arafat, S F Rahman, M S Utomo, S Kassegn. On-chip testing of a carbon-based platform for electro-adsorption of glutamate. Heliyon. vol 8. issue 5. 2022-06-01. PMID:35647339. |
in this study, we introduce a microfluidic system that enables us to emulate the uptake of glutamate into the carbon matrix. |
2022-06-01 |
2023-08-13 |
Not clear |
| Y Whulanza, Y B Arafat, S F Rahman, M S Utomo, S Kassegn. On-chip testing of a carbon-based platform for electro-adsorption of glutamate. Heliyon. vol 8. issue 5. 2022-06-01. PMID:35647339. |
the uptake is controlled using electrical pulses to incorporate glutamate ions into the carbon matrix through electro-adsorption. |
2022-06-01 |
2023-08-13 |
Not clear |
| Y Whulanza, Y B Arafat, S F Rahman, M S Utomo, S Kassegn. On-chip testing of a carbon-based platform for electro-adsorption of glutamate. Heliyon. vol 8. issue 5. 2022-06-01. PMID:35647339. |
the stimulated carbon matrix was able to decrease glutamate concentration by up to 40%. |
2022-06-01 |
2023-08-13 |
Not clear |
| Y Whulanza, Y B Arafat, S F Rahman, M S Utomo, S Kassegn. On-chip testing of a carbon-based platform for electro-adsorption of glutamate. Heliyon. vol 8. issue 5. 2022-06-01. PMID:35647339. |
a release model was used to study the profile of glutamate release from the carbon matrix at a potential of 0-1.5 v. this study showed that a burst release of glutamate was evident at an applied voltage higher than 0.5 v. ultimately, the mts (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2h-tetrazolium) test for cytotoxicity indicated a cell viability of more than 80% for the carbon matrix. |
2022-06-01 |
2023-08-13 |
Not clear |
| Wenhao Wang, Fangqin Fu, Zhengwei Huang, Wenhua Wang, Minglong Chen, Xiao Yue, Jintao Fu, Xiaoqian Feng, Ying Huang, Chuanbin Wu, Xin Pa. Inhalable Biomimetic Protein Corona-Mediated Nanoreactor for Self-Amplified Lung Adenocarcinoma Ferroptosis Therapy. ACS nano. 2022-05-16. PMID:35575209. |
to address these issues, an inhalable nanoreactor was proposed by spontaneously adsorbing biomimetic protein corona (pc) composed of matrix metalloproteinase 2 responsive gelatin and glutamate (glu) on the surface of cationic nanostructured lipid carriers (nlc) core loaded with ferrocene (fc) and fluvastatin. |
2022-05-16 |
2023-08-13 |
Not clear |
| Ciro De Luca, Assunta Virtuoso, Michele Papa, Francesco Certo, Giuseppe Maria Vincenzo Barbagallo, Roberto Altier. Regional Development of Glioblastoma: The Anatomical Conundrum of Cancer Biology and Its Surgical Implication. Cells. vol 11. issue 8. 2022-04-23. PMID:35456027. |
in this review, we analyze the anatomical and biological basis of gliomagenesis considering neural stem cells, the spatiotemporal diversity of astrocytes, microglia, neurons and glutamate transporters, extracellular matrix and the peritumoral environment. |
2022-04-23 |
2023-08-13 |
Not clear |
| Vasiliki Kommata, Evaggelia Alexopoulou, Elentina K Argyrousi, Catherine R Dermo. Pleiotrophin, nitric oxide and glutamate AMPA receptors in chick cerebellum morphogenesis. The International journal of developmental biology. 2022-03-03. PMID:35238393. |
the present study questioned the spatio-temporal expression pattern of pleiotrophin, an extracellular matrix growth factor, during the morphogenesis of embryonic cerebellum and the roles of ionotropic ampa glutamate receptors and the diffusible neuromodulator nitric oxide (no) in the proliferation pattern of egl granule cell progenitors. |
2022-03-03 |
2023-08-13 |
chicken |
| Shaikh Jamal Uddin, Md Fahim Hasan, Mohasana Afroz, Dipto Kumer Sarker, Razina Rouf, Muhammad Torequl Islam, Jamil A Shilpi, Mohammad S Mubara. Curcumin and its Multi-target Function Against Pain and Inflammation: An Update of Pre-clinical Data. Current drug targets. vol 22. issue 6. 2021-11-26. PMID:32981501. |
available pre-clinical data suggest the ameliorating effect of curcumin in pain and inflammation is rendered through the modulation of pain pathways, including inhibition of a number of pro-inflammatory mediators, inhibition of oxidative stress and cyclooxygenase-2 (cox-2), down-regulation of ca2+/calmodulin-depend protein kinase ii (camkiiα) and calcium channels like transient receptor potential (trp), modulation of metabotropic glutamate receptor-2 (mglu2), modulation of monoamine system, inhibition of jak2/stat3 signaling pathway, remodeling of extracellular matrix proteins, inhibition of apoptosis, inhibition of jnk/mapk and erk/creb signaling pathway, and activation of the opioid system. |
2021-11-26 |
2023-08-13 |
Not clear |
| Sadayuki Hashioka, James G McLarnon, Andis Klegeri. Diversity and Regulation of Astrocyte Neurotoxicity in Alzheimer's Disease. Current Alzheimer research. 2021-11-18. PMID:34789126. |
we identify reactive oxygen and nitrogen species, tumor necrosis factor α (tnf-α), glutamate, and matrix metalloproteinase (mmp)-9 as molecules that can be directly toxic to neurons and are released by reactive astrocytes. |
2021-11-18 |
2023-08-13 |
human |
| Yu Tian, Matthew Tirrell, Carley Davis, Jeffrey A Wesso. Protein primary structure correlates with calcium oxalate stone matrix preference. PloS one. vol 16. issue 9. 2021-11-17. PMID:34555074. |
to verify essential details of this model and identify an explanation for phase selectivity observed in weakly charged proteins, we have examined primary structures of major proteins preferring either the matrix phase or the urine phase for their contents of aspartate, glutamate, lysine and arginine; amino acids that would represent fixed charges at normal urine ph of 6-7. |
2021-11-17 |
2023-08-13 |
Not clear |