All Relations between matrix compartment and nitrogen monoxide

Publication Sentence Publish Date Extraction Date Species
Samia Mahmoud Manawy, Eman Mohamed Faruk, Rabab Fawzy Hindawy, Mahmoud M Hassan, Diaa M G Farrag, Mansour A E Bashar, Hanan Fouad, Rania Abubaker Bagabir, Dina Allam Abdelmaksoud Hassan, Ahmed Mohammed Zaazaa, Mohamed Ghazy Attia Hablas, K Mostafa Kama. Modulation of the Sirtuin-1 signaling pathway in doxorubicin-induced nephrotoxicity (synergistic amelioration by resveratrol and pirfenidone). Tissue & cell. vol 87. 2024-02-27. PMID:38412579. renal tissue was collected to assess matrix metalloproteinase-9 (mmp9), inflammatory and apoptotic markers: tumor necrosis factor-alpha (tnf- β, caspase-3, cyclo-oxygenase-2 (cox-2), and oxidative stress markers: nitric oxide (no), glutathione (gsh), malondialdehyde (mda), and superoxide dismutase (sod). 2024-02-27 2024-03-01 rat
Sung Un Kang, Haeng Jun Kim, Sukhwal Ma, Doo-Yi Oh, Jeon Yeob Jang, Chorong Seo, Yun Sang Lee, Chul-Ho Ki. Liquid plasma promotes angiogenesis through upregulation of endothelial nitric oxide synthase-induced extracellular matrix metabolism: potential applications of liquid plasma for vascular injuries. Cell communication and signaling : CCS. vol 22. issue 1. 2024-02-19. PMID:38374138. liquid plasma promotes angiogenesis through upregulation of endothelial nitric oxide synthase-induced extracellular matrix metabolism: potential applications of liquid plasma for vascular injuries. 2024-02-19 2024-02-22 Not clear
Hannah Youngblood, Patricia V Schoenlein, Louis R Pasquale, W Daniel Stamer, Yutao Li. Estrogen dysregulation, intraocular pressure, and glaucoma risk. Experimental eye research. 2023-11-16. PMID:37956940. based upon its known activities, estrogen signaling may promote iop homeostasis by affecting extracellular matrix turnover, focal adhesion assembly, actin stress fiber formation, mechanosensation, and nitric oxide production. 2023-11-16 2023-11-20 Not clear
Fang-Fang Xu, Fan Zheng, Ye Chen, Yang Wang, Shao-Bo Ma, Weng Ding, Le-Sha Zhang, Ji-Zheng Guo, Chang-Bo Zheng, Bing She. Role of thrombospondin-1 in high-salt-induced mesenteric artery endothelial impairment in rats. Acta pharmacologica Sinica. 2023-11-06. PMID:37932403. the matrix glycoprotein thrombospondin-1 (thbs1) modulates nitric oxide (no) signaling in endothelial cells. 2023-11-06 2023-11-08 rat
Xiaosha Wang, Maoren Wang, Hanhan Liu, Karl Mercieca, Julia Prinz, Yuan Feng, Verena Prokosc. The Association between Vascular Abnormalities and Glaucoma-What Comes First? International journal of molecular sciences. vol 24. issue 17. 2023-09-09. PMID:37686017. in this study, several biomarkers of glaucoma progression from a vascular perspective, including endothelin-1 (et-1), nitric oxide, vascular endothelial growth factor (vegf), and matrix metalloproteinases (mmps), were identified and subsequently assessed for their potential as pharmacological intervention targets. 2023-09-09 2023-10-07 chicken
Gisela Soledad Gualdoni, Camila Barril, Patricia Verónica Jacobo, Liliana Nazareth Pacheco Rodríguez, Elisa Cebra. Involvement of metalloproteinase and nitric oxide synthase/nitric oxide mechanisms in early decidual angiogenesis-vascularization of normal and experimental pathological mouse placenta related to maternal alcohol exposure. Frontiers in cell and developmental biology. vol 11. 2023-09-06. PMID:37670932. these placental angiogenic events are highly dependent on the coordination of several mechanisms at the early maternal-fetal interface, and one of them is the expression and activity of matrix metalloproteinases (mmps) and endothelial nitric oxide synthases (noss). 2023-09-06 2023-10-07 mouse
Zhifang Tang, Hanzhen Feng, Xusheng Chen, Shuiyan Shao, Chuan L. SNORC knockdown alleviates inflammation, autophagy defect and matrix degradation of chondrocytes in osteoarthritis development. Molecular and cellular biochemistry. 2023-09-02. PMID:37659033. knocking down snorc in il-1β-induced chondrocytes obviously suppressed the production of nitric oxide (no), il-6, tumor necrosis factor (tnf)-α and prostaglandin e2 (pge2) to alleviate inflammation, and reduced the protein levels of a disintegrin and metalloproteinase with thrombospondin 5 (adamts5) and matrix metallopeptidase (mmp)13 and elevated collagen type 2 alpha 1 (col2a1) level to improve matrix degradation. 2023-09-02 2023-09-07 rat
Laisla Zanetoni Martins, Maria Luiza Santos da Silva, Serginara David Rodrigues, Sáskia Estela Biasotti Gomes, Laura Molezini, Elen Rizzi, Marcelo Freitas Montenegro, Carlos Alan Dias-Junio. Sodium Nitrite Attenuates Reduced Activity of Vascular Matrix Metalloproteinase-2 and Vascular Hyper-Reactivity and Increased Systolic Blood Pressure Induced by the Placental Ischemia Model of Preeclampsia in Anesthetized Rats. International journal of molecular sciences. vol 24. issue 16. 2023-08-26. PMID:37628999. placental ischemia is suggested as the primary trigger of preeclampsia-associated impairments of both endothelium-derived nitric oxide (no) and the vascular activity of extracellular matrix metalloproteinase-2 (mmp-2). 2023-08-26 2023-09-07 rat
Bingqing Wang, Yuqing Yang, Yichen Wang, Yanxin Yang, Yi Li, Chenxi Hu, Changyue Xu. Matrix stiffness regulates neovascular homeostasis through autophagy in nude mice. Journal of cellular physiology. 2023-08-11. PMID:37565586. endothelial function markers, such as endothelial nitric oxide synthase and e-selectin, were downregulated as the matrix stiffness increased. 2023-08-11 2023-08-16 mouse
Judit Hodrea, Minh Ngoc Tran, Balazs Besztercei, Timea Medveczki, Attila J Szabo, Laszlo Őrfi, Illes Kovacs, Andrea Feket. Sigma-1 Receptor Agonist Fluvoxamine Ameliorates Fibrotic Response of Trabecular Meshwork Cells. International journal of molecular sciences. vol 24. issue 14. 2023-07-29. PMID:37511406. furthermore, flu demonstrated its protective effects by increasing the production of nitric oxide and facilitating the degradation of the extracellular matrix through the elevation of cathepsin k. these findings suggest that the s1r could be a novel target for the development of anti-fibrotic drugs and offer a new therapeutic approach for glaucoma. 2023-07-29 2023-08-14 mouse
Cristal Jesus Toghi, Laisla Zanetoni Martins, Leonardo Lopes Pacheco, Edileia Souza Paula Caetano, Bruna Rahal Mattos, Elen Rizzi, Carlos Alan Dias-Junio. Pravastatin Prevents Increases in Activity of Metalloproteinase-2 and Oxidative Stress, and Enhances Endothelium-Derived Nitric Oxide-Dependent Vasodilation in Gestational Hypertension. Antioxidants (Basel, Switzerland). vol 12. issue 4. 2023-04-28. PMID:37107314. an impaired redox state leads to reduction in circulating nitric oxide (no) levels and activation of extracellular matrix metalloproteinases (mmps). 2023-04-28 2023-08-14 rat
Guangqin Li, Jiahui Xian, Suisheng Li, Hui Su, Peisen Liao, Shihan Wang, Yawei Zhang, Wenqian Yang, Jun Yang, Yamei Sun, Yaling Jia, Qinglin Liu, Qinghua Li. Electrocatalytic Synthesis of Essential Amino Acids from Nitric Oxide Using Atomically Dispersed Fe on N-doped Carbon. Angewandte Chemie (International ed. in English). 2023-04-18. PMID:37072344. herein, we demonstrate an innovative method for artificial synthesis of essential α-amino acids from nitric oxide (no) by reacting with α-keto acids through electrocatalytic process with atomically dispersed fe supported on n-doped carbon matrix (ad-fe/nc) as the catalyst. 2023-04-18 2023-08-14 Not clear
Yifei Sun, Keiichi Asano, Lauriane Sedes, Anna Cantalupo, Jens Hansen, Ravi Iyengar, Martin J Walsh, Francesco Ramire. Dissecting aortic aneurysm in Marfan syndrome is associated with losartan-sensitive transcriptomic modulation of aortic cells. JCI insight. 2023-04-06. PMID:37022786. smc3 highly express genes related to extracellular matrix formation and nitric oxide signaling, whereas ec4 transcriptional profile is enriched in smc, fibroblast, and immune cell-related genes. 2023-04-06 2023-08-14 mouse
Chin-Feng Hsuan, Sean I F Teng, Chih-Neng Hsu, Daniel Liao, Allen Jiun-Wei Chang, Hsiao-Lin Lee, Siow-Wey Hee, Yi-Cheng Chang, Lee-Ming Chuan. Emerging Therapy for Diabetic Cardiomyopathy: From Molecular Mechanism to Clinical Practice. Biomedicines. vol 11. issue 3. 2023-03-29. PMID:36979641. the molecular mechanism of diabetic cardiomyopathy includes impaired nutrient-sensing signaling, dysregulated autophagy, impaired mitochondrial energetics, altered fuel utilization, oxidative stress and lipid peroxidation, advanced glycation end-products, inflammation, impaired calcium homeostasis, abnormal endothelial function and nitric oxide production, aberrant epidermal growth factor receptor signaling, the activation of the renin-angiotensin-aldosterone system and sympathetic hyperactivity, and extracellular matrix accumulation and fibrosis. 2023-03-29 2023-08-14 Not clear
Adityanarayan Mohapatra, Jagannath Mondal, Padmanaban Sathiyamoorthy, Ayeskanta Mohanty, Vishnu Revuri, Santhosh Kalash Rajendrakumar, Yong-Kyu Lee, In-Kyu Par. Thermosusceptible Nitric-Oxide-Releasing Nitrogel for Strengthening Antitumor Immune Responses with Tumor Collagen Diminution and Deep Tissue Delivery during NIR Laser-Assisted Photoimmunotherapy. ACS applied materials & interfaces. 2023-03-10. PMID:36896475. herein, a cancer treatment approach that combines photothermal therapy (ptt) and nitric oxide (no) gas therapy for tumor extracellular matrix (ecm) degradation, along with nlg919, an indoleamine 2,3-dioxygenase (ido) inhibitor that reduces tryptophan catabolism to kynurenine, and dmxaa, a stimulator of interferon gene (sting) agonist that stimulates antigen cross-presentation, is proposed to overcome this issue. 2023-03-10 2023-08-14 Not clear
Hugh S Markus, Frank Erik de Leeu. Cerebral small vessel disease: Recent advances and future directions. International journal of stroke : official journal of the International Stroke Society. vol 18. issue 1. 2022-12-28. PMID:36575578. recent advances have implicated molecular processes related to endothelial dysfunction, nitric oxide synthesis, blood-brain barrier integrity, maintenance and repair of the extracellular matrix, and inflammation. 2022-12-28 2023-08-14 Not clear
Sahar Foshati, Maryam Poursadeghfard, Zahra Heidari, Reza Aman. The efficacy and safety of ginger supplementation in patients with multiple sclerosis: A rationale and study protocol for a double-blind randomized controlled trial. Health science reports. vol 6. issue 1. 2022-12-26. PMID:36570345. therefore, we aim to determine the effect of ginger supplementation on neurofilament light chain, matrix metalloproteinase-9, interleukin-17, nitric oxide, complete and differential blood counts, disability status, quality of life, gastrointestinal symptoms, and body mass index (bmi) in ms patients. 2022-12-26 2023-08-14 Not clear
Seonyoung Kim, Ji Yeon Lee, Jeong-Yong Park, YongGyeong Kim, Chang-Ho Kan. Nutrients. vol 14. issue 22. 2022-11-29. PMID:36432555. all lab strains (lacticaseibacillus rhamnosus mg4706, mg4709, and mg4711) inhibited nitric oxide (no)/inducible nitric oxide synthase (inos) in p. gingivalis lps-activated raw264.7 cells and pro-inflammatory cytokines (il-1β and il-6) and matrix metalloproteinase (mmp-8 and mmp-9) in hgf-1 cells. 2022-11-29 2023-08-16 human
Longxiang Huang, Zhenni Wei, Xiaohui Wang, Chunlin Lan, Yihua Zhu, Qin Y. AZD6738 Decreases Intraocular Pressure and Inhibits Fibrotic Response in Trabecular Meshwork through CHK1/P53 Pathway. Biochemical pharmacology. 2022-11-08. PMID:36347274. further, we demonstrated that azd6738 reduces cell viability and migration, and inhibit the expression of fibrosis-related factors including fibronectin (fn), α-smooth muscle actin (α-sma), laminin subunit beta 1 (lamb1), matrix metallopeptidase (mmp) family including mmp2 and mmp9, collagen Ⅰ (col1), and collagen Ⅳ (col4), reduce gap junctions, altered cytoskeleton and nitric oxide production in tgf-β1-induced human trabecular meshwork cells (htmcs) through the chk1/p53 pathway, which were affected aqueous humor (ah) production and outflow pathway. 2022-11-08 2023-08-14 mouse
Vishal Patel, Amit Joharapurkar, Mukul Jai. Therapeutic Potential of Diacerein in Management of Pain. Current drug research reviews. vol 14. issue 3. 2022-10-25. PMID:36281831. the effect of diacerein and rhein on mediators of pain, such as transient receptor potential cation channel subfamily v (trpv1), substance p, glutamate, inflammatory cytokines, nitric oxide, matrix metalloproteinases, histamine, palmitoylethanolamide, nuclear factor-kappa b (nfkb), and prostaglandin, has also been discussed. 2022-10-25 2023-08-14 Not clear