| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vishal Patel, Amit Joharapurkar, Mukul Jai. Therapeutic Potential of Diacerein in Management of Pain. Current drug research reviews. vol 14. issue 3. 2022-10-25. PMID:36281831. |
the effect of diacerein and rhein on mediators of pain, such as transient receptor potential cation channel subfamily v (trpv1), substance p, glutamate, inflammatory cytokines, nitric oxide, matrix metalloproteinases, histamine, palmitoylethanolamide, nuclear factor-kappa b (nfkb), and prostaglandin, has also been discussed. |
2022-10-25 |
2023-08-14 |
Not clear |
| Alia H Mallah, Mahmoud Amr, Arda Gozen, Juana Mendenhall, Bernard J Van-Wie, Nehal I Abu-Lai. Interleukin 1β and lipopolysaccharides induction dictate chondrocyte morphological properties and reduce cellular roughness and adhesion energy comparatively. Biointerphases. vol 17. issue 5. 2022-09-30. PMID:36180273. |
nitric oxide, prostaglandin 2 (pge2), and matrix metalloproteinases 3 (mmp3) contents; viability of cells; and extracellular matrix components were quantified. |
2022-09-30 |
2023-08-14 |
cattle |
| Qi Wang, Jing Peng, Yang Liu, Yang Tian, Jie Li, Yao-Yao Ren, Jian Gu, Rui Ta. [Therapeutic effects of alkaloids in Tibetan medicine Bangna (Aconiti Penduli et Aconiti Flavi Radix) on osteoarthritis rats and mechanisms]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 17. 2022-09-27. PMID:36164879. |
the protein expression of inflammatory factors cyclooxygenase-2(cox-2), inducible nitric oxide synthetase(inos), tumor necrosis factor-α(tnf-α), and interleukin-1β(il-1β) in each group were detected by western blot, and the protein expression of matrix metalloprotease-13(mmp-13), aggrecan, collagen Ⅱ, fibroblast growth factor 2(fgf2) by immunofluorescence staining. |
2022-09-27 |
2023-08-14 |
rat |
| T A Kuznetsova, B G Andryukov, S F Polovov, A K Gazh. Modern aspects of burn injury immunopathogenesis and immuno-biochemical markers of wound healing (review of literature). Klinicheskaia laboratornaia diagnostika. vol 67. issue 8. 2022-09-12. PMID:36095081. |
the characteristics of the main immuno-biochemical markers of burn injury (cytokines and growth factors, nitric oxide, matrix metalloproteases, bacteria concentration levels) are present. |
2022-09-12 |
2023-08-14 |
Not clear |
| Taryn E Murray, Christy M Richards, Victoria N Robert-Gostlin, Anna K Bernath, Ivan A Lindhout, Andis Klegeri. Potential neurotoxic activity of diverse molecules released by astrocytes. Brain research bulletin. 2022-08-21. PMID:35988785. |
some of these molecules are neuroprotective and inflammation resolving while others, including reactive oxygen species (ros), nitric oxide (no), matrix metalloproteinase (mmp)-9, l-glutamate, and tumor necrosis factor α (tnf), are well-established toxins known to cause damage to surrounding cells and tissues. |
2022-08-21 |
2023-08-14 |
cat |
| Velmurugan Shanmugham, Ravi Subba. Capsanthin from Capsicum annum fruits exerts anti-glaucoma, antioxidant, anti-inflammatory activity, and corneal pro-inflammatory cytokine gene expression in a benzalkonium chloride-induced rat dry eye model. Journal of food biochemistry. 2022-07-27. PMID:35892258. |
capsanthin ameliorated in reducing oxidative stress by increasing serum antioxidant levels such as glutathione peroxidase (gpx), nitric oxide (no), and lactoferrin (ltf) and inhibiting matrix metalloproteinases 2 and 9 (mmp2 and mmp9) (p < .0001). |
2022-07-27 |
2023-08-14 |
rat |
| Tatyana A Kuznetsova, Boris G Andryukov, Natalia N Besednov. Modern Aspects of Burn Injury Immunopathogenesis and Prognostic Immunobiochemical Markers (Mini-Review). Biotech (Basel (Switzerland)). vol 11. issue 2. 2022-07-13. PMID:35822791. |
characterization of primary immunobiochemical markers of burn injury (cytokines, growth factors, c-reactive protein, procalcitonin, presepsin, matrix metalloproteinases, reactive oxygen species, nitric oxide, hemostasis parameters) is presented. |
2022-07-13 |
2023-08-14 |
Not clear |
| Ruiqiang Hang, Jiahui Wang, Xue Tian, Ruifeng Wu, Ruiyue Hang, Yuyu Zhao, Yonghua Sun, Honggang Wan. Resveratrol promotes osteogenesis and angiogenesis through mediating immunology of senescent macrophages. Biomedical materials (Bristol, England). 2022-07-13. PMID:35830846. |
the immune microenvironment created by senescent macrophages upon resveratrol stimulation can promote osteogenesis and angiogenesis, as manifested by upregulated proliferation, alkaline phosphatase activity, type i collagen secretion, and extracellular matrix mineralization of senescent osteoblasts as well as nitric oxide production, migration, and in vitro angiogenesis of senescent endothelial cells. |
2022-07-13 |
2023-08-14 |
Not clear |
| Shiying Zeng, Shisheng Li, Qinglai Tang, Ayinuer Tuerdi, Xinying Tong, Xiaojun Tang, Danhui Yin, Mengmeng Li, Qian Yan. Association of matrix metalloproteinase-9 and nitric oxide with hypertension in obstructive sleep apnea. Laryngoscope investigative otolaryngology. vol 7. issue 3. 2022-06-23. PMID:35734065. |
association of matrix metalloproteinase-9 and nitric oxide with hypertension in obstructive sleep apnea. |
2022-06-23 |
2023-08-14 |
Not clear |
| Shiying Zeng, Shisheng Li, Qinglai Tang, Ayinuer Tuerdi, Xinying Tong, Xiaojun Tang, Danhui Yin, Mengmeng Li, Qian Yan. Association of matrix metalloproteinase-9 and nitric oxide with hypertension in obstructive sleep apnea. Laryngoscope investigative otolaryngology. vol 7. issue 3. 2022-06-23. PMID:35734065. |
at the same time, the serum levels of matrix metalloproteinase-9 (mmp-9) and nitric oxide (no) in patients with osa are also changed in osa patients. |
2022-06-23 |
2023-08-14 |
Not clear |
| Andrew Barnes, Elizabeth Mazzio, Ramesh Badisa, Karam F Solima. A High-Through Put Pro-inflammatory screening of natural products using mouse RAW 264.7 macrophages indicate a more significant number of pro-inflammatory natural herbal products than anti-inflammatory. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35557433. |
in the present study, we are reporting (without a confounding variable of cell death and with matrix controls run for every extract) an enormous number; 444 natural products to evoke pro-inflammatory effects in raw 264.7 cells producing nitric oxide at levels equal to lps and ifn-g, using the same library. |
2022-05-13 |
2023-08-13 |
mouse |
| Yun Zhang, Shuaijun Li, Peisheng Jin, Ting Shang, Ruizhu Sun, Laiya Lu, Kaijin Guo, Jiping Liu, Yongjuan Tong, Junbang Wang, Sanhong Liu, Chen Wang, Yubin Kang, Wenmin Zhu, Qian Wang, Xiaoren Zhang, Feng Yin, Yi Eve Sun, Lei Cu. Dual functions of microRNA-17 in maintaining cartilage homeostasis and protection against osteoarthritis. Nature communications. vol 13. issue 1. 2022-05-04. PMID:35508470. |
supplementation of exogenous mir-17 or its endogenous induction by growth differentiation factor 5, effectively prevented oa by simultaneously targeting pathological catabolic factors including matrix metallopeptidase-3/13 (mmp3/13), aggrecanase-2 (adamts5), and nitric oxide synthase-2 (nos2). |
2022-05-04 |
2023-08-13 |
Not clear |
| Vasiliki Kommata, Evaggelia Alexopoulou, Elentina K Argyrousi, Catherine R Dermo. Pleiotrophin, nitric oxide and glutamate AMPA receptors in chick cerebellum morphogenesis. The International journal of developmental biology. 2022-03-03. PMID:35238393. |
the present study questioned the spatio-temporal expression pattern of pleiotrophin, an extracellular matrix growth factor, during the morphogenesis of embryonic cerebellum and the roles of ionotropic ampa glutamate receptors and the diffusible neuromodulator nitric oxide (no) in the proliferation pattern of egl granule cell progenitors. |
2022-03-03 |
2023-08-13 |
chicken |
| Jessica F Hoffman, Vernieda B Vergara, John F Kalinic. Protein Expression in the Gastrocnemius Muscle of a Rodent Shrapnel-Injury Model. International journal of toxicology. 2021-12-24. PMID:34951546. |
in this study, using homogenates of rat gastrocnemius muscle implanted with pellets of military-relevant metals, we investigated expression of inos and enos, enzymes involved in nitric oxide production, as well as mmp-2 and mmp-9, matrix metalloproteinases associated with muscle repair. |
2021-12-24 |
2023-08-13 |
rat |
| Qian Wang, Jiefeng Huang, Shuaijun Li, Yun Zhang, Ruizhu Sun, Jiaxin Ren, Si Shi, Lei Cu. Fermentation supernatant of Staphylococcus aureus drives catabolism in chondrocytes via NF-κB signaling mediated increase of cholesterol metabolism. Experimental cell research. vol 410. issue 1. 2021-12-11. PMID:34848206. |
we further demonstrated that enhancement of ch25h/cyp7b1/rorα axis resulted from fs exposure was mediated by activation of nf-κb signaling, along with upregulation in catabolic factors including matrix metallopeptidases (mmp3 and mmp13), aggrecanase-2 (adamts5), and nitric oxide synthase-2 (nos2) in chondrocytes. |
2021-12-11 |
2023-08-13 |
Not clear |
| Farah Yassine, Sabreen F Fostok, Nataly Naser Al Deen, Rabih S Talhou. Endotoxin Triggers Tumor Initiation Events in Nontumorigenic Breast Epithelial Cells and Enhances Invasion-Related Phenotype in Pretumorigenic and Tumorigenic Breast Epithelial Cells. International journal of inflammation. vol 2021. 2021-12-07. PMID:34868543. |
results showed that short-term et exposure upregulated matrix metalloproteinase-9 (mmp-9) activity in nontumorigenic mammary epithelial cells of mouse (scp2) and human origins (hmt-3522 s1; s1) and upregulated inflammatory mediators including nitric oxide (no) and interleukin 1- |
2021-12-07 |
2023-08-13 |
mouse |
| Yue-Yuan Chen, Xiao-Jie Yan, Xiao-Hua Jiang, Feng-Lai Lu, Xue-Rong Yang, Dian-Peng L. Vicenin 3 ameliorates ECM degradation by regulating the MAPK pathway in SW1353 chondrocytes. Experimental and therapeutic medicine. vol 22. issue 6. 2021-11-06. PMID:34737801. |
these chondrocytes were pretreated with vicenin 3 (0, 5 and 20 µm) for 1 h and subsequently stimulated with il-1β (10 ng/ml) for 24 h. nitric oxide (no) production was measured using the griess reaction, whereas the production of prostaglandin e2 (pge2), matrix metalloproteinases (mmps), a disintegrin-like and metalloproteinase with thrombospondin motifs (adamtss), collagen type ii and aggrecan were measured using elisa. |
2021-11-06 |
2023-08-13 |
Not clear |
| Zhiting Sun, Xiaoxiao Wang, Jing Liu, Zhihong Wang, Weiwei Wang, Deling Kong, Xigang Len. ICG/l-Arginine Encapsulated PLGA Nanoparticle-Thermosensitive Hydrogel Hybrid Delivery System for Cascade Cancer Photodynamic-NO Therapy with Promoted Collagen Depletion in Tumor Tissues. Molecular pharmaceutics. vol 18. issue 3. 2021-11-02. PMID:33427470. |
here, an approach synergistically combining pdt and nitric oxide (no) gas therapy along with destruction of the tumor extracellular matrix (ecm) was presented to eliminate cancer. |
2021-11-02 |
2023-08-13 |
Not clear |
| Kiyoshi Kikuchi, Ko-Ichi Kawahara, Hisaaki Uchikado, Naohisa Miyagi, Terukazu Kuramoto, Tomoya Miyagi, Yoko Morimoto, Takashi Ito, Salunya Tancharoen, Naoki Miura, Kazunori Takenouchi, Yoko Oyama, Binita Shrestha, Fumiyo Matsuda, Yoshihiro Yoshida, Shinihiro Arimura, Kentaro Mera, Ko-Ichi Tada, Narimasa Yoshinaga, Ryuichi Maenosono, Yoshiko Ohno, Teruto Hashiguchi, Ikuro Maruyama, Minoru Shigemor. Potential of edaravone for neuroprotection in neurologic diseases that do not involve cerebral infarction. Experimental and therapeutic medicine. vol 2. issue 5. 2021-10-21. PMID:22977573. |
aside from its hydroxyl radical scavenging effect, edaravone has been found to have beneficial effects on inflammation, matrix metalloproteinases, nitric oxide production and apoptotic cell death. |
2021-10-21 |
2023-08-12 |
Not clear |
| Do Young Kim, Jiyuan Piao, Jeong Seop Park, Dahyeon Lee, Hyun Sook Hon. Substance P ameliorates TNF-α-mediated impairment of human aortic vascular cells in vitro. Clinical and experimental pharmacology & physiology. vol 48. issue 9. 2021-09-30. PMID:34060109. |
on endothelial injury, the expression of extracellular matrix (ecm) is enhanced and nitric oxide (no) bioavailability becomes deficient. |
2021-09-30 |
2023-08-13 |
human |