| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Jurasz, G Sawicki, M Duszyk, J Sawicka, C Miranda, I Mayers, M W Radomsk. Matrix metalloproteinase 2 in tumor cell-induced platelet aggregation: regulation by nitric oxide. Cancer research. vol 61. issue 1. 2001-02-01. PMID:11196190. |
matrix metalloproteinase 2 in tumor cell-induced platelet aggregation: regulation by nitric oxide. |
2001-02-01 |
2023-08-12 |
human |
| N Cohen, D Robinson, J Ben-Ezzer, Y Hemo, A Hasharoni, Y Wolmann, I Otremski, Z Nev. Reduced NO accumulation in arthrotic cartilage by exposure to methylene blue. Acta orthopaedica Scandinavica. vol 71. issue 6. 2001-01-18. PMID:11145393. |
addition of methylene blue to the growth medium lowered nitric oxide accumulation and prevented matrix degradation in the cultured cartilage discs. |
2001-01-18 |
2023-08-12 |
human |
| S Archer, S Ric. Primary pulmonary hypertension: a vascular biology and translational research "Work in progress". Circulation. vol 102. issue 22. 2000-12-22. PMID:11094047. |
pharmacological and gene therapies aimed at enhancing the activity of prostacyclin, nitric oxide synthases, and kv channels or at inhibiting endothelin and matrix metalloproteinases are promising areas for future development. |
2000-12-22 |
2023-08-12 |
Not clear |
| S A Fisher, B L Langille, D Srivastav. Apoptosis during cardiovascular development. Circulation research. vol 87. issue 10. 2000-11-30. PMID:11073880. |
physical forces, growth factors, and extracellular matrix drive vascular cell survival pathways, and considerable evidence points to local nitric oxide production as an important but complex regulator of vascular cell death. |
2000-11-30 |
2023-08-12 |
Not clear |
| M W Orth, T L Peters, K A Chlebek-Brow. Cartilage turnover in embryonic chick tibial explant cultures. Poultry science. vol 79. issue 7. 2000-11-09. PMID:10901200. |
increases in matrix metalloproteinase activity and nitric oxide production are detected in cartilage concurrently with release of proteoglycans into media. |
2000-11-09 |
2023-08-12 |
chicken |
| A R Ami. Type II interleukin-1beta receptor: a candidate for gene therapy in human arthritis. Clinical orthopaedics and related research. issue 379 Suppl. 2000-11-03. PMID:11039768. |
human interleukin-1beta (5-10 ng/ml) induced nitric oxide, prostaglandin e2 and matrix metalloprotease production in bovine or human chondrocytes, which could be inhibited by 500 pg/ml of type ii interleukin-1 receptor. |
2000-11-03 |
2023-08-12 |
human |
| A M Loening, I E James, M E Levenston, A M Badger, E H Frank, B Kurz, M E Nuttall, H H Hung, S M Blake, A J Grodzinsky, M W Lar. Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis. Archives of biochemistry and biophysics. vol 381. issue 2. 2000-10-31. PMID:11032407. |
together, these data suggest that injurious compression can stimulate cell death as well as a range of biomechanical and biochemical alterations to the matrix and, possibly, chondrocyte nitric oxide expression. |
2000-10-31 |
2023-08-12 |
cattle |
| F S Shihab, H Yi, W M Bennett, T F Ando. Effect of nitric oxide modulation on TGF-beta1 and matrix proteins in chronic cyclosporine nephrotoxicity. Kidney international. vol 58. issue 3. 2000-10-12. PMID:10972680. |
effect of nitric oxide modulation on tgf-beta1 and matrix proteins in chronic cyclosporine nephrotoxicity. |
2000-10-12 |
2023-08-12 |
Not clear |
| K D Burn. Angiotensin II and its receptors in the diabetic kidney. American journal of kidney diseases : the official journal of the National Kidney Foundation. vol 36. issue 3. 2000-09-21. PMID:10977776. |
at(2)-receptor activation is associated with increased intrarenal nitric oxide production, stimulation of natriuresis, and inhibition of cell growth and matrix synthesis, effects that oppose those of kidney at(1) receptors. |
2000-09-21 |
2023-08-12 |
Not clear |
| J I Fenton, K A Chlebek-Brown, T L Peters, J P Caron, M W Ort. Glucosamine HCl reduces equine articular cartilage degradation in explant culture. Osteoarthritis and cartilage. vol 8. issue 4. 2000-09-12. PMID:10903879. |
nitric oxide, proteoglycan and matrix metalloproteinases (mmp) released into conditioned media and tissue proteoglycan synthesis were measured as indicators of cartilage metabolism. |
2000-09-12 |
2023-08-12 |
human |
| J A Edwards, F Denis, P J Talbo. Activation of glial cells by human coronavirus OC43 infection. Journal of neuroimmunology. vol 108. issue 1-2. 2000-08-25. PMID:10900340. |
this virus also modulated the activity of matrix metalloproteinases-2 and -9 and augmented nitric oxide production in both u-373mg cells and the human microglial cell line chme-5. |
2000-08-25 |
2023-08-12 |
human |
| H C Ludwig, R Akhavan-Shigari, S Rausch, K Schallock, C Quentin, V Bockermann, H Kolend. Expression of focal adhesion kinase (p125 FAK) and proline-rich tyrosine kinase 2 (PYK2/CAKb) in cerebral metastases, correlation with VEGF-R-, ecNOS III-labelling and morphometric data. Anticancer research. vol 20. issue 3A. 2000-08-17. PMID:10928051. |
nitric oxide, which is produced in metastases by three different nos isozymes is capable of antagonizing the binding of fak to matrix integrins. |
2000-08-17 |
2023-08-12 |
Not clear |
| K Johnson, A Jung, A Murphy, A Andreyev, J Dykens, R Terkeltau. Mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralization. Arthritis and rheumatism. vol 43. issue 7. 2000-08-08. PMID:10902761. |
mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralization. |
2000-08-08 |
2023-08-12 |
Not clear |
| K Johnson, A Jung, A Murphy, A Andreyev, J Dykens, R Terkeltau. Mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralization. Arthritis and rheumatism. vol 43. issue 7. 2000-08-08. PMID:10902761. |
increased chondrocyte nitric oxide (no) and peroxynitrite production appears to modulate decreased matrix synthesis and increased mineralization in osteoarthritis (oa). |
2000-08-08 |
2023-08-12 |
Not clear |
| M Cao, M Stefanovic-Racic, H I Georgescu, F H Fu, C H Evan. Does nitric oxide help explain the differential healing capacity of the anterior cruciate, posterior cruciate, and medial collateral ligaments? The American journal of sports medicine. vol 28. issue 2. 2000-05-11. PMID:10750993. |
this study compared the ability of rabbit medial collateral ligament, posterior cruciate ligament, and anterior cruciate ligament tissue to synthesize nitric oxide, and determined its effects on matrix synthesis, an important component of ligament repair. |
2000-05-11 |
2023-08-12 |
rabbit |
| M Cao, M Stefanovic-Racic, H I Georgescu, F H Fu, C H Evan. Does nitric oxide help explain the differential healing capacity of the anterior cruciate, posterior cruciate, and medial collateral ligaments? The American journal of sports medicine. vol 28. issue 2. 2000-05-11. PMID:10750993. |
endogenously synthesized nitric oxide was also able to inhibit collagen synthesis as well as proteoglycan synthesis by the two cruciate ligaments, but had little effect on matrix synthesis by the medial collateral ligament. |
2000-05-11 |
2023-08-12 |
rabbit |
| M Cao, M Stefanovic-Racic, H I Georgescu, F H Fu, C H Evan. Does nitric oxide help explain the differential healing capacity of the anterior cruciate, posterior cruciate, and medial collateral ligaments? The American journal of sports medicine. vol 28. issue 2. 2000-05-11. PMID:10750993. |
we propose a novel hypothesis, based on nitric oxide production and matrix synthesis, that may help explain why the two cruciate ligaments have such limited healing capacity compared with the medial collateral ligament. |
2000-05-11 |
2023-08-12 |
rabbit |
| A Kastrati, J Dirschinger, A Schömi. Genetic risk factors and restenosis after percutaneous coronary interventions. Herz. vol 25. issue 1. 2000-04-11. PMID:10713908. |
completed or ongoing studies have focused on polymorphisms of genes encoding for proteins interfering with lipid metabolism, hemostasis, nitric oxide production, inflammatory mechanisms, smc proliferation and matrix production. |
2000-04-11 |
2023-08-12 |
Not clear |
| W Eberhardt, T Beeg, K F Beck, S Walpen, S Gauer, H Böhles, J Pfeilschifte. Nitric oxide modulates expression of matrix metalloproteinase-9 in rat mesangial cells. Kidney international. vol 57. issue 1. 2000-03-08. PMID:10620188. |
nitric oxide modulates expression of matrix metalloproteinase-9 in rat mesangial cells. |
2000-03-08 |
2023-08-12 |
rat |
| W Eberhardt, T Beeg, K F Beck, S Walpen, S Gauer, H Böhles, J Pfeilschifte. Nitric oxide modulates expression of matrix metalloproteinase-9 in rat mesangial cells. Kidney international. vol 57. issue 1. 2000-03-08. PMID:10620188. |
nitric oxide modulates expression of matrix metalloproteinase-9 in rat mesangial cells. |
2000-03-08 |
2023-08-12 |
rat |