All Relations between matrix compartment and nitrogen monoxide

Publication Sentence Publish Date Extraction Date Species
Wen-Feng Xiao, Yu-Sheng Li, Ang Deng, Yun-Tao Yang, Miao H. Functional role of hedgehog pathway in osteoarthritis. Cell biochemistry and function. vol 38. issue 2. 2021-01-29. PMID:31833076. usually in oa, activation of hedgehog induces up-regulation of the expression of hypertrophic markers, including type x collagen, increases production of nitric oxide and prostaglandin e2, several matrix-degrading enzymes including matrix metalloproteinase and a disintegrin and metalloproteinase with thrombospondin motifs in human knee joint cartilage leading to cartilage degeneration, and thus contributes in oa. 2021-01-29 2023-08-13 human
Qianru Jin, Anil Bhatta, Jayson V Pagaduan, Xing Chen, Hoku West-Foyle, Jiayu Liu, Annie Hou, Dan Berkowitz, Scot C Kuo, Frederic B Askin, Thao D Nguyen, David H Gracias, Lewis H Rome. Biomimetic human small muscular pulmonary arteries. Science advances. vol 6. issue 13. 2020-11-24. PMID:32232160. these microvessels feature anatomically accurate layering and patterning of aligned human smooth muscle cells, extracellular matrix, and endothelial cells and exhibit notable increases in endothelial longevity and nitric oxide production. 2020-11-24 2023-08-13 human
Zhao-Heng Lin, Jing Jin, Xi-Yun Sha. The effects of estradiol on inflammatory and endothelial dysfunction in rats with preeclampsia. International journal of molecular medicine. vol 45. issue 3. 2020-11-02. PMID:31985028. the activities of nitric oxide (no) and inducible no synthase (inos), the levels of inflammatory cytokines [interleukin (il)‑1β, il‑6, interferon‑γ and monocyte chemoattractant protein‑1], adherence factors (cd49d, intracellular adhesion molecule 1 and lymphocyte function‑associated antigen‑1) and uterine angiogenic status (fms‑like tyrosine kinase‑1, vascular cell adhesion molecule and matrix metalloproteinase 2/9) were also assessed. 2020-11-02 2023-08-13 rat
Jie Yu, Yongliang Jiang, Mingqi Tu, Binjun Liao, Jianqiao Fan. Investigating Prescriptions and Mechanisms of Acupuncture for Chronic Stable Angina Pectoris: An Association Rule Mining and Network Analysis Study. Evidence-based complementary and alternative medicine : eCAM. vol 2020. 2020-10-29. PMID:33110434. moreover, potential mechanisms of acupuncture for treating csap involved the regulation of autonomic nerve function, the content of matrix metalloproteinase-9 (mmp-9), volume and the equivalent block of coronary artery calcified plaque (cacp), endothelin (et), and nitric oxide (no), neutrophil-lymphocyte ratio (nlr), the content of c-reactive protein (crp), and tumor necrosis factor- 2020-10-29 2023-08-13 Not clear
Matthew J Rossman, Rachel A Gioscia-Ryan, Zachary S Clayton, Michael P Murphy, Douglas R Seal. Targeting mitochondrial fitness as a strategy for healthy vascular aging. Clinical science (London, England : 1979). vol 134. issue 12. 2020-10-07. PMID:32584404. vascular aging is driven in large part by oxidative stress, which reduces bioavailability of nitric oxide and promotes alterations in the extracellular matrix. 2020-10-07 2023-08-13 Not clear
Li Zeng, Cai Zhi Xiao, Zi Ting Deng, Rong Heng L. Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-10-01. PMID:28167976. the expression of c-terminal crosslinking telopeptide of type ii collagen, hydroxyproline, a disintegrin and metalloproteinase with thrombospondin motifs, matrix metalloproteinase, interleukin-1 beta, nitric oxide, prostaglandin e2, heat-shock protein 70, transforming growth factor-beta, osteoprotegerin, and receptor activator of nuclear factor 2020-10-01 2023-08-13 rat
Atsushi Mizuma, Midori A Yenar. Anti-Inflammatory Targets for the Treatment of Reperfusion Injury in Stroke. Frontiers in neurology. vol 8. 2020-10-01. PMID:28936196. inflammatory mediators involved in this response include cytokines, chemokines, adhesion molecules, and several immune molecule effectors such as matrix metalloproteinases-9, inducible nitric oxide synthase, nitric oxide, and reactive oxygen species. 2020-10-01 2023-08-13 Not clear
Zile, Napp. Diastolic Heart Failure. Current treatment options in cardiovascular medicine. vol 2. issue 5. 2020-09-30. PMID:11096548. mechanism-targeted therapy (future directions): modify neurohumoral activation using renin, angiotensin, and aldosterone system antagonists (ace inhibitors, angiotensin ii receptor blockade, aldosterone and renin antagonist); endothelin antagonists; nitric oxide agonists; and atrial natruretic peptide agonists; alter intracellular mechanisms; alter extracellular matrix structures. 2020-09-30 2023-08-12 Not clear
Evgeny Sidorov, Dharambir K Sanghera, Jairam K P Vanamal. Biomarker for Ischemic Stroke Using Metabolome: A Clinician Perspective. Journal of stroke. vol 21. issue 1. 2020-09-30. PMID:30732441. although failed to find specific biomarkers, they discovered several important metabolite-stroke associations which belong to three pathophysiological mechanisms: excitotoxicity with activation of glutamate, resulting in the increase of glutamate derivatives proline and pyroglutamate; oxidative stress with production of free radicals and perturbed concentrations of uric acid, matrix metalloproteinase-9, branch-chained amino acids, sphingolipids, homocysteine, asymmetric dimethylarginine, nitric oxide and folate cycle metabolites; and stroke mediated inflammation, affecting phospholipid metabolism with perturbed levels of lysophosphatidylethanolamine and lysophosphatidylcholine. 2020-09-30 2023-08-13 Not clear
Abdulrazaq Yahaya, Damilola Babatunde, Lamidi W B Olaniyan, Oluranti Agbool. Application of chromatographic techniques in the analysis of total nitrosamines in water. Heliyon. vol 6. issue 3. 2020-09-28. PMID:32154411. nitrosamines are a potential source of nitric oxide (no) which can bind with metals present in the sample matrix leading to formation of metal - nitrosyl complexes and dissolved metals have the potential to increase the total nitrosamines in water. 2020-09-28 2023-08-13 Not clear
Yifan Wu, Zhanghong Wang, Zeng Lin, Xin Fu, Jingdi Zhan, Kehe Y. Salvianolic Acid A Has Anti-Osteoarthritis Effect Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32581777. we evaluated the expression of pro-inflammatory mediators and cartilage matrix catabolic enzymes in chondrocytes by elisa, griess reaction, immunofluorescence, and western blot, which includes nitric oxide (no), tumor necrosis factor-alpha (tnf-α), interleukin-6 (il-6), prostaglandin e2 (pge2), inducible nitric oxide synthase (inos), cyclooxygenase-2 (cox-2), mmps (mmp-3, mmp-13), and adamts-5. 2020-09-28 2023-08-13 Not clear
Angel Mercy Sylus, Hanumanthappa Nandeesha, Thiagaraju Chitr. Matrix metalloproteinase-9 increases and Interleukin-10 reduces with increase in body mass index in polycystic ovary syndrome: A cross-sectional study. International journal of reproductive biomedicine. vol 18. issue 8. 2020-09-28. PMID:32923927. obesity, inflammation and alterations in matrix metalloproteinase-9 (mmp-9) and nitric oxide (no) levels are involved in the development of polycystic ovary syndrome (pcos). 2020-09-28 2023-08-13 Not clear
Undurti N Da. Bioactive lipids in intervertebral disc degeneration and its therapeutic implications. Bioscience reports. vol 39. issue 10. 2020-09-15. PMID:31533969. recent studies showed that ivd degeneration could be an inflammatory condition characterized by increased production of matrix metalloproteinases, tnf-α, nitric oxide, il-6, il-17, il-9, and prostaglandin e2, and decreased formation of anti-inflammatory molecules such as lipoxin a4. 2020-09-15 2023-08-13 Not clear
Douglas R Seals, Erzsebet E Nagy, Kerrie L Morea. Aerobic exercise training and vascular function with ageing in healthy men and women. The Journal of physiology. vol 597. issue 19. 2020-09-09. PMID:31077372. vascular ageing is driven by oxidative stress, which reduces nitric oxide (no) bioavailability and stimulates changes in the extracellular matrix. 2020-09-09 2023-08-13 Not clear
Jian-Sheng Wang, Wei-Wei Xiao, Yong-Sheng Zhong, Xue-Dong Li, Shi-Xin Du, Peng Xie, Gui-Zhou Zheng, Jing-Ming Ha. Galectin-3 deficiency protects lipopolysaccharide-induced chondrocytes injury via regulation of TLR4 and PPAR-γ-mediated NF-κB signaling pathway. Journal of cellular biochemistry. vol 120. issue 6. 2020-07-20. PMID:30565728. in addition, repression of gal-3 obviously impeded lps-stimulated inflammation damage as exemplified by a reduction in the release of inflammatory mediators interleukin (il)-1β, il-6, and tumor necrosis factor-α, as well as the production of nitric oxide and prostaglandin e2 (pge2) concomitant with the downregulation of matrix metalloproteinases (mmp)-13 and mmp-3 expression in atdc5 cells after lps administration. 2020-07-20 2023-08-13 Not clear
Jyotsna Joshi, Mohammadreza Dehghan Abnavi, Chandrasekhar R Kothapall. Synthesis and secretome release by human bone marrow mesenchymal stem cell spheroids within three-dimensional collagen hydrogels: Integrating experiments and modelling. Journal of tissue engineering and regenerative medicine. vol 13. issue 10. 2020-07-16. PMID:31350819. we here elucidated the synthesis and deposition of ecm (e.g., elastin, sulfated glycosaminoglycans, hyaluronan, collagen type iii, laminin, fibrillin, lysyl oxidase, and nitric oxide synthases), matrix metalloproteinases (mmps) and their inhibitors (timps), and other secretome (cytokines, chemokines, and growth factors) in adult human bm-msc spheroid cultures within three-dimensional collagen gels. 2020-07-16 2023-08-13 human
Regina A Nascimento, Jose S Possomato-Vieira, Giselle F Bonacio, Elen Rizzi, Carlos A Dias-Junio. Reductions of Circulating Nitric Oxide are Followed by Hypertension during Pregnancy and Increased Activity of Matrix Metalloproteinases-2 and -9 in Rats. Cells. vol 8. issue 11. 2020-07-06. PMID:31703340. reductions of circulating nitric oxide are followed by hypertension during pregnancy and increased activity of matrix metalloproteinases-2 and -9 in rats. 2020-07-06 2023-08-13 rat
Regina A Nascimento, Jose S Possomato-Vieira, Giselle F Bonacio, Elen Rizzi, Carlos A Dias-Junio. Reductions of Circulating Nitric Oxide are Followed by Hypertension during Pregnancy and Increased Activity of Matrix Metalloproteinases-2 and -9 in Rats. Cells. vol 8. issue 11. 2020-07-06. PMID:31703340. hypertensive pregnancy has been associated with reduced nitric oxide (no), bioavailability, and increased activity of matrix metalloproteinases (mmps). 2020-07-06 2023-08-13 rat
Carmela Rita Balistreri, Maurizio Forte, Ernesto Greco, Francesco Paneni, Elena Cavarretta, Giacomo Frati, Sebastiano Sciarrett. An overview of the molecular mechanisms underlying development and progression of bicuspid aortic valve disease. Journal of molecular and cellular cardiology. vol 132. 2020-07-01. PMID:31103478. among these, genes involved in the regulation of extracellular matrix remodelling, epithelial to mesenchymal transition and nitric oxide metabolism appear to be the main contributors to bav pathogenesis. 2020-07-01 2023-08-13 Not clear
M Carla Crescitelli, M Belén Rauschemberger, Sabrina Cepeda, Marisa Sandoval, Virginia L Massheime. Role of estrone on the regulation of osteoblastogenesis. Molecular and cellular endocrinology. vol 498. 2020-06-24. PMID:31525430. the hormone significantly increased cell proliferation (38% above control), nitric oxide production (108% above control), alkaline phosphatase activity (50% above control), in addition to stimulation of extracellular matrix mineralization. 2020-06-24 2023-08-13 Not clear