| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li Lu, Xiaorong Li, Pingxiang Xu, Yan Zheng, Xiaomin Wan. Tenuigenin down-regulates the release of nitric oxide, matrix metalloproteinase-9 and cytokines from lipopolysaccharide-stimulated microglia. Neuroscience letters. vol 650. 2018-03-19. PMID:28392358. |
tenuigenin down-regulates the release of nitric oxide, matrix metalloproteinase-9 and cytokines from lipopolysaccharide-stimulated microglia. |
2018-03-19 |
2023-08-13 |
rat |
| Wern Cui Chu, Shipin Zhang, Timothy J Sng, Yu Jie Ong, Wen-Li Tan, Vivien Y Ang, Casper B Foldager, Wei Seong To. Distribution of pericellular matrix molecules in the temporomandibular joint and their chondroprotective effects against inflammation. International journal of oral science. vol 9. issue 1. 2018-03-15. PMID:28282029. |
the responses of the chondrocytes were analysed using gene expression, nitric oxide release and matrix metalloproteinase (mmp)-13 production measures. |
2018-03-15 |
2023-08-13 |
rat |
| Hemant Kumar, Alexander E Ropper, Soo-Hong Lee, Inbo Ha. Propitious Therapeutic Modulators to Prevent Blood-Spinal Cord Barrier Disruption in Spinal Cord Injury. Molecular neurobiology. vol 54. issue 5. 2018-03-09. PMID:27194298. |
major proteins involved in bscb disruption in sci focuses on the actions of matrix metalloproteinases (mmps), tumor necrosis factor alpha (tnf-α), heme oxygenase-1 (ho-1), angiopoietins (angs), bradykinin, nitric oxide (no), and endothelins (ets) in bscb disruption and repair. |
2018-03-09 |
2023-08-13 |
Not clear |
| Arsalan Alizadeh, Scott M Dyck, Hardeep Kataria, Ghazaleh M Shahriary, Dung H Nguyen, Kallivalappil T Santhosh, Soheila Karimi-Abdolrezae. Neuregulin-1 positively modulates glial response and improves neurological recovery following traumatic spinal cord injury. Glia. vol 65. issue 7. 2018-03-07. PMID:28456012. |
we also found a decrease in proinflammatory factors including il-1β, tnf-α, matrix metalloproteinases (mmp-2 and 9) and nitric oxide after injury. |
2018-03-07 |
2023-08-13 |
rat |
| Amanda S Harper-Leatherman, Jean Marie Wallace, Debra R Roliso. Cytochrome c Stabilization and Immobilization in Aerogels. Methods in molecular biology (Clifton, N.J.). vol 1504. 2018-01-15. PMID:27770420. |
the au~cyt.c superstructures exhibit rapid gas-phase recognition of nitric oxide (no) within the bioaerogel matrix, as facilitated by the high-quality pore structure of the aerogel, while remaining viable for weeks at room temperature. |
2018-01-15 |
2023-08-13 |
Not clear |
| Jianguo Xu, Handong Wang, Seok Joon Won, Jayinee Basu, David Kapfhamer, Raymond A Swanso. Microglial activation induced by the alarmin S100B is regulated by poly(ADP-ribose) polymerase-1. Glia. vol 64. issue 11. 2018-01-04. PMID:27444121. |
exogenous s100b added to primary microglial cultures induced a rapid change in microglial morphology, upregulation of il-1β, tnfα, and inos gene expression, and release of matrix metalloproteinase 9 and nitric oxide. |
2018-01-04 |
2023-08-13 |
Not clear |
| Wen Wu, Caroline Perrin-Sarrado, Hui Ming, Isabelle Lartaud, Philippe Maincent, Xian-Ming Hu, Anne Sapin-Minet, Caroline Gauche. Polymer nanocomposites enhance S-nitrosoglutathione intestinal absorption and promote the formation of releasable nitric oxide stores in rat aorta. Nanomedicine : nanotechnology, biology, and medicine. vol 12. issue 7. 2017-10-02. PMID:27184095. |
s-nitrosoglutathione (gsno) loaded polymeric nanoparticles incorporated into an alginate and chitosan matrix, were developed to increase the effective gsno loading capacity, a nitric oxide (no) donor, and to sustain its release from the intestine following oral administration. |
2017-10-02 |
2023-08-13 |
rat |
| Li-Na Gao, Qi-Shuai Feng, Xin-Fang Zhang, Qiang-Song Wang, Yuan-Lu Cu. Tetrandrine suppresses articular inflammatory response by inhibiting pro-inflammatory factors via NF-κB inactivation. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 34. issue 9. 2017-09-19. PMID:26748661. |
moreover, atdc5 cells well responded to lps induced pro-inflammatory mediators secretion and tissue degradation, and tetrandrine could also inhibit the production of nitric oxide and prostaglandin e2 , as well as the expression of matrix metalloproteinase (mmp)-3 and tissue inhibitor of metalloproteinase (timp)-1 via inhibiting iκbα phosphorylation and degradation. |
2017-09-19 |
2023-08-13 |
rat |
| Irene Cuadrado, Borja Castejon, Ana M Martin, Marta Saura, Paula Reventun-Torralba, Jose Luis Zamorano, Carlos Zaragoz. Nitric Oxide Induces Cardiac Protection by Preventing Extracellular Matrix Degradation through the Complex Caveolin-3/EMMPRIN in Cardiac Myocytes. PloS one. vol 11. issue 9. 2017-08-15. PMID:27649573. |
nitric oxide induces cardiac protection by preventing extracellular matrix degradation through the complex caveolin-3/emmprin in cardiac myocytes. |
2017-08-15 |
2023-08-13 |
mouse |
| Irene Cuadrado, Borja Castejon, Ana M Martin, Marta Saura, Paula Reventun-Torralba, Jose Luis Zamorano, Carlos Zaragoz. Nitric Oxide Induces Cardiac Protection by Preventing Extracellular Matrix Degradation through the Complex Caveolin-3/EMMPRIN in Cardiac Myocytes. PloS one. vol 11. issue 9. 2017-08-15. PMID:27649573. |
inhibition of extracellular matrix degradation by nitric oxide (no) induces cardiac protection against coronary ischemia/reperfusion (ir). |
2017-08-15 |
2023-08-13 |
mouse |
| Iwona Bil-Lula, Han-Bin Lin, Dariusz Biały, Magdalena Wawrzyńska, Lucas Diebel, Jolanta Sawicka, Mieczyslaw Woźniak, Grzegorz Sawick. Subthreshold nitric oxide synthase inhibition improves synergistic effects of subthreshold MMP-2/MLCK-mediated cardiomyocyte protection from hypoxic injury. Journal of cellular and molecular medicine. vol 20. issue 6. 2017-07-05. PMID:26992120. |
injury of myocardium during ischaemia/reperfusion (i/r) is a complex and multifactorial process involving uncontrolled protein phosphorylation, nitration/nitrosylation by increased production of nitric oxide and accelerated contractile protein degradation by matrix metalloproteinase-2 (mmp-2). |
2017-07-05 |
2023-08-13 |
Not clear |
| Pichaya Jumnongprakhon, Piyarat Govitrapong, Chainarong Tocharus, Jiraporn Tocharu. Melatonin promotes blood-brain barrier integrity in methamphetamine-induced inflammation in primary rat brain microvascular endothelial cells. Brain research. vol 1646. 2017-06-22. PMID:27268413. |
herein, we demonstrated that melatonin reduced the level of the inflammatory mediators, including intercellular adhesion molecules (icam)-1, vascular cell adhesion molecules (vcam)-1, matrix metallopeptidase (mmp)-9, inducible nitric oxide synthase (inos), and nitric oxide (no) caused by meth. |
2017-06-22 |
2023-08-13 |
rat |
| Jianyun Wang, Qianqian Yang, Yaxing Nie, Hao Guo, Fan Zhang, Xueyan Zhou, Xiaoxing Yi. Tetrahydrobiopterin contributes to the proliferation of mesangial cells and accumulation of extracellular matrix in early-stage diabetic nephropathy. The Journal of pharmacy and pharmacology. vol 69. issue 2. 2017-06-19. PMID:28033650. |
nitric oxide (no) plays an important role in the progression of early-stage diabetic nephropathy (dn), which is found to contribute to extracellular matrix (ecm) accumulation in mesangial cells (mcs). |
2017-06-19 |
2023-08-13 |
Not clear |
| A Speziali, M Delcogliano, M Tei, G Placella, M Chillemi, R Tiribuzi, G Cerull. Chondropenia: current concept review. Musculoskeletal surgery. vol 99. issue 3. 2017-06-15. PMID:26068954. |
in addition nitric oxide and reactive oxygen species modulate the physiopathology of the condral matrix inducing apoptosis of chondrocytes through a mitochondria-dependent pathway. |
2017-06-15 |
2023-08-13 |
Not clear |
| Hyun Sook Hwang, In Young Park, Hyun Ah Kim, Soo Young Cho. PEP-1-GRX-1 Modulates Matrix Metalloproteinase-13 and Nitric Oxide Expression of Human Articular Chondrocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 41. issue 1. 2017-06-06. PMID:28214840. |
pep-1-grx-1 modulates matrix metalloproteinase-13 and nitric oxide expression of human articular chondrocytes. |
2017-06-06 |
2023-08-13 |
mouse |
| Baoqi Yan, Dongsheng Wang, Shuwei Dong, Zhangrui Cheng, Lidong Na, Mengqi Sang, Hongzao Yang, Zhiqiang Yang, Shidong Zhang, Zuoting Ya. Palmatine inhibits TRIF-dependent NF-κB pathway against inflammation induced by LPS in goat endometrial epithelial cells. International immunopharmacology. vol 45. 2017-06-01. PMID:28236763. |
our results showed that palmatine treatment inhibited the release of tumor necrosis factor (tnf)-α, interleukin (il)-1β, il-6, nitric oxide (no), matrix metalloproteinase (mmp)-9 and mmp-2. |
2017-06-01 |
2023-08-13 |
Not clear |
| Neal L Millar, George A C Murrell, Iain B McInne. Inflammatory mechanisms in tendinopathy - towards translation. Nature reviews. Rheumatology. vol 13. issue 2. 2017-05-25. PMID:28119539. |
key inflammatory mediators - such as cytokines, nitric oxide, prostaglandins and lipoxins - play crucial parts in modulating changes in the extracellular matrix within tendinopathy. |
2017-05-25 |
2023-08-13 |
human |
| Si Eun Park, Sa Rang Lim, Hyung-Kyoon Choi, Jeehyeon Ba. Triazine herbicides inhibit relaxin signaling and disrupt nitric oxide homeostasis. Toxicology and applied pharmacology. vol 307. 2017-05-23. PMID:27431321. |
in addition, downstream target genes of the relaxin pathway including nitric oxide (no) synthase 2 (nos2), nos3, matrix metallopeptidase 9 (mmp9), and vascular endothelial growth factor (vegf) were downregulated in their ovaries. |
2017-05-23 |
2023-08-13 |
mouse |
| Sangeetha Gupta, Uma Sharma, Naranamangalam R Jagannathan, Yogendra Kumar Gupt. Neuroprotective effect of lercanidipine in middle cerebral artery occlusion model of stroke in rats. Experimental neurology. vol 288. 2017-05-12. PMID:27794423. |
biochemical markers estimated in rat brain cortex 24h post-mcao were oxidative stress (malondialdehyde, reduced glutathione, nitric oxide, superoxide dismutase), blood brain barrier damage (matrix metalloproteinases-2 and -9) and apoptotic (caspase-3 and -9). |
2017-05-12 |
2023-08-13 |
rat |
| b' Agnieszka Irena Mazur-Bialy, Ewa Poche\\xc4\\x8. Riboflavin Reduces Pro-Inflammatory Activation of Adipocyte-Macrophage Co-culture. Potential Application of Vitamin B2 Enrichment for Attenuation of Insulin Resistance and Metabolic Syndrome Development. Molecules (Basel, Switzerland). vol 21. issue 12. 2017-04-28. PMID:27983705.' |
the apoptosis of adipocytes and macrophages as well as tumor necrosis factor-alpha (tnf-α), interleukin 6 (il-6), interleukin 1beta (il-1β), monocyte chemotactic protein 1 (mcp-1), high-mobility group box 1 (hmgb1), transforming growth factor-beta 1 (tgfβ), interleukin 10 (il-10), inducible nitric oxide synthase (inos), nitric oxide (no), matrix metalloproteinase 9 (mmp-9), tissue inhibitor of metalloproteinases-1 (timp-1) expression and release, macrophage migration and adipokines (adiponectin and leptin) were determined. |
2017-04-28 |
2023-08-13 |
Not clear |