Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
b' Agnieszka Irena Mazur-Bialy, Ewa Poche\\xc4\\x8. Riboflavin Reduces Pro-Inflammatory Activation of Adipocyte-Macrophage Co-culture. Potential Application of Vitamin B2 Enrichment for Attenuation of Insulin Resistance and Metabolic Syndrome Development. Molecules (Basel, Switzerland). vol 21. issue 12. 2017-04-28. PMID:27983705.' |
the apoptosis of adipocytes and macrophages as well as tumor necrosis factor-alpha (tnf-α), interleukin 6 (il-6), interleukin 1beta (il-1β), monocyte chemotactic protein 1 (mcp-1), high-mobility group box 1 (hmgb1), transforming growth factor-beta 1 (tgfβ), interleukin 10 (il-10), inducible nitric oxide synthase (inos), nitric oxide (no), matrix metalloproteinase 9 (mmp-9), tissue inhibitor of metalloproteinases-1 (timp-1) expression and release, macrophage migration and adipokines (adiponectin and leptin) were determined. |
2017-04-28 |
2023-08-13 |
Not clear |
Mei-Lin Wang, Shyh-Hsiang Lin, Yuan-Yu Hou, Yue-Hwa Che. Suppression of Lipid Accumulation by Indole-3-Carbinol Is Associated with Increased Expression of the Aryl Hydrocarbon Receptor and CYP1B1 Proteins in Adipocytes and with Decreased Adipocyte-Stimulated Endothelial Tube Formation. International journal of molecular sciences. vol 17. issue 8. 2017-04-03. PMID:27527145. |
furthermore, i3c inhibited cm-stimulated endothelial tube formation, which was accompanied by the modulated secretion of angiogenic factors in adipocytes, including vascular endothelial growth factor, interleukin-6, matrix metalloproteinases, and nitric oxide. |
2017-04-03 |
2023-08-13 |
Not clear |
Vinicius P Garcia, Helena N M Rocha, Gustavo M Silva, Tatiana A G Amaral, Niels H Secher, Antonio C L Nóbrega, Lauro C Vianna, Natália G Roch. Exogenous l-arginine reduces matrix metalloproteinase-2 and -9 activities and oxidative stress in patients with hypertension. Life sciences. vol 157. 2017-02-08. PMID:27287681. |
increased matrix metalloproteinases activity and reduced nitric oxide (no) bioavailability contributes to development of hypertension and this may be associated with a defective l-arginine-no pathway. |
2017-02-08 |
2023-08-13 |
Not clear |
Jae Woo Ki. Effect of Nitric Oxide on the Expression of Matrix Metalloproteinase and Its Association with Migration of Cultured Trabecular Meshwork Cells. Korean journal of ophthalmology : KJO. vol 30. issue 1. 2016-12-20. PMID:26865806. |
effect of nitric oxide on the expression of matrix metalloproteinase and its association with migration of cultured trabecular meshwork cells. |
2016-12-20 |
2023-08-13 |
Not clear |
Jae Woo Ki. Effect of Nitric Oxide on the Expression of Matrix Metalloproteinase and Its Association with Migration of Cultured Trabecular Meshwork Cells. Korean journal of ophthalmology : KJO. vol 30. issue 1. 2016-12-20. PMID:26865806. |
to determine the effect of exogenous nitric oxide (no) on the migration of trabecular meshwork (tm) cells and its association with expression of matrix metalloproteinases (mmps). |
2016-12-20 |
2023-08-13 |
Not clear |
Joao Leandro Chaguri, Antonio Francisco Godinho, Daniel França Horta, Victor Hugo Gonçalves-Rizzi, Jose Sergio Possomato-Vieira, Regina Aparecida Nascimento, Carlos Alan Dias-Junio. Exposure to fipronil elevates systolic blood pressure and disturbs related biomarkers in plasma of rats. Environmental toxicology and pharmacology. vol 42. 2016-12-15. PMID:26773360. |
while fipronil resulted in higher concentrations of endothelin-1, reduced antioxidant capacity and lower levels of circulating matrix metalloproteinase 2 (mmp-2) and nitric oxide (no) metabolites compared to control group, no alteration was observed in serum biomarkers of renal and hepatic/biliary functional abilities. |
2016-12-15 |
2023-08-13 |
rat |
Ana Patricia Fernandez, Julia Serrano Masa, María Atocha Guedan, Hunter S Futch, Ricardo Martínez-Murill. Adrenomedullin Expression in Alzheimer's Brain. Current Alzheimer research. vol 13. issue 4. 2016-12-15. PMID:26923268. |
in a previous study, we found that am exerts a neuroprotective action in the brain and that this effect may be mediated by regulation of nitric oxide synthases, matrix metalloproteases, and inflammatory mediators. |
2016-12-15 |
2023-08-13 |
Not clear |
Uwe Wollin. Subantimicrobial-dose doxycycline monohydrate in dermatology. Wiener medizinische Wochenschrift (1946). vol 165. issue 23-24. 2016-12-13. PMID:26564206. |
subantimicrobial doxycycline is an anti-inflammatory drug that decreases cathelicidin, kallikrein 5, reactive oxygen species, nitric oxide, and matrix metalloproteinases. |
2016-12-13 |
2023-08-13 |
Not clear |
Maryam Rahmati, Ali Mobasheri, Masoud Mozafar. Inflammatory mediators in osteoarthritis: A critical review of the state-of-the-art, current prospects, and future challenges. Bone. vol 85. 2016-12-13. PMID:26812612. |
pro-inflammatory cytokines, reactive oxygen species (ros), nitric oxide, matrix degrading enzymes and biomechanical stress are major factors responsible for the progression of oa in synovial joints. |
2016-12-13 |
2023-08-13 |
Not clear |
Jin-Woo Jeong, Hye Hyeon Lee, Ki Won Lee, Ki Young Kim, Sung Goo Kim, Su Hyun Hong, Gi-Young Kim, Cheol Park, Ho Kyoung Kim, Young Whan Choi, Yung Hyun Cho. Mori folium inhibits interleukin-1β-induced expression of matrix metalloproteinases and inflammatory mediators by suppressing the activation of NF-κB and p38 MAPK in SW1353 human chondrocytes. International journal of molecular medicine. vol 37. issue 2. 2016-10-27. PMID:26707272. |
therefore, in the present study, we investigated whether mori folium water extract (mf) inhibited the catabolic effects of il-1β in vitro, and also whether it inhibited the matrix metalloproteinases (mmps), inducible nitric oxide (no) synthase (inos) and cyclooxygenase-2 (cox-2) through the attenuation of nuclear factor-κb (nf-κb) and mitogen activated protein kinase (mapk) pathways in sw1353 human chondrocytes. |
2016-10-27 |
2023-08-13 |
human |
Satoshi Suda, Bing Yang, Krystal Schaar, Xiaopei Xi, Jennifer Pido, Kaushik Parsha, Jaroslaw Aronowski, Sean I Savit. Autologous Bone Marrow Mononuclear Cells Exert Broad Effects on Short- and Long-Term Biological and Functional Outcomes in Rodents with Intracerebral Hemorrhage. Stem cells and development. vol 24. issue 23. 2016-09-09. PMID:26414707. |
we found that mnc-treated young rats showed a reduction in the neurotrophil infiltration, the number of inducible nitric oxide synthase-positive cells, and the expression of inflammatory-related signalings such as the high-mobility group protein box-1, s100 calcium binding protein b, matrix metalloproteinase-9, and aquaporin 4. |
2016-09-09 |
2023-08-13 |
rat |
Konstantinos Ravanos, Themistoklis Dagklis, Stamatios Petousis, Chrysoula Margioula-Siarkou, Yannis Prapas, Nikolaos Prapa. Factors implicated in the initiation of human parturition in term and preterm labor: a review. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 31. issue 9. 2016-08-22. PMID:26303116. |
cytokines, prostaglandins, nitric oxide and steroids seem also to induce ripening by mediating remodeling of the extracellular matrix and collagen. |
2016-08-22 |
2023-08-13 |
human |
Anna Scislowska-Czarnecka, Dariusz Szmigiel, Michel Genet, Christine Dupont-Gillain, Elzbieta Pamula, Elzbieta Kolaczkowsk. Oxygen plasma surface modification augments poly(L-lactide-co-glycolide) cytocompatibility toward osteoblasts and minimizes immune activation of macrophages. Journal of biomedical materials research. Part A. vol 103. issue 12. 2016-08-11. PMID:26014580. |
importantly, macrophages (raw 264.7), one of the key cells initiating inflammation and bone resorption, responded significantly less vigorously to the modified polymers, expressing/releasing lower amounts of nitric oxide, matrix metalloproteinases (mmp-9), and pro-inflammatory cytokines (tnf-α, il-6, il-12p70, ifn-γ, il-10). |
2016-08-11 |
2023-08-13 |
Not clear |
Qi Xing, Lijun Zhang, Travis Redman, Shaohai Qi, Feng Zha. Nitric oxide regulates cell behavior on an interactive cell-derived extracellular matrix scaffold. Journal of biomedical materials research. Part A. vol 103. issue 12. 2016-08-11. PMID:26074441. |
nitric oxide regulates cell behavior on an interactive cell-derived extracellular matrix scaffold. |
2016-08-11 |
2023-08-13 |
human |
Vita Wonoputri, Cindy Gunawan, Sanly Liu, Nicolas Barraud, Lachlan H Yee, May Lim, Rose Ama. Copper Complex in Poly(vinyl chloride) as a Nitric Oxide-Generating Catalyst for the Control of Nitrifying Bacterial Biofilms. ACS applied materials & interfaces. vol 7. issue 40. 2016-08-05. PMID:26418515. |
in this study, catalytic generation of nitric oxide by a copper(ii) complex embedded within a poly(vinyl chloride) matrix in the presence of nitrite (source of nitric oxide) and ascorbic acid (reducing agent) was shown to effectively control the formation and dispersion of nitrifying bacteria biofilms. |
2016-08-05 |
2023-08-13 |
Not clear |
Lee J Winchester, Sudhakar Veeranki, Srikanth Givvimani, Suresh C Tyag. Homocysteine elicits an M1 phenotype in murine macrophages through an EMMPRIN-mediated pathway. Canadian journal of physiology and pharmacology. vol 93. issue 7. 2016-07-27. PMID:26118387. |
hyperhomocysteinemia (hhcy) is associated with inflammatory diseases and is known to increase the production of reactive oxygen species (ros), matrix metalloproteinase (mmp)-9, and inducible nitric oxide synthase, and to decrease endothelial nitric oxide production. |
2016-07-27 |
2023-08-13 |
Not clear |
Jin-Woo Jeong, Hye Hyeon Lee, Eun-Ok Choi, Ki Won Lee, Ki Young Kim, Sung Goo Kim, Su Hyun Hong, Gi-Young Kim, Cheol Park, Ho Kyoung Kim, Young Whan Choi, Yung Hyun Cho. Schisandrae Fructus Inhibits IL-1β-Induced Matrix Metalloproteinases and Inflammatory Mediators Production in SW1353 Human Chondrocytes by Suppressing NF-κB and MAPK Activation. Drug development research. vol 76. issue 8. 2016-06-29. PMID:26443270. |
sf attenuated il-1β-induced expression and activity of matrix metalloproteinase (mmp)-1, mmp-3, and mmp-13 and also reduced the elevated levels of cyclooxygenase-2 and inducible nitric oxide synthase associated with the inhibition of prostaglandin e2 and nitric oxide production in il-1β-stimulated sw1353 chondrocytes. |
2016-06-29 |
2023-08-13 |
human |
Nora V Butta, Ihosvany Fernández-Bello, Francisco J López-Longo, Víctor Jiménez-Yust. Endothelial Dysfunction and Altered Coagulation As Mediators of Thromboembolism in Behçet Disease. Seminars in thrombosis and hemostasis. vol 41. issue 6. 2016-06-27. PMID:26276934. |
these factors, together with the increased levels of homocysteine observed in bd patients, induce the endothelial cell expression of adhesion molecules (vcam-1 and icam-1) and tissue factor; the release of cytokines, soluble cd40l (scd40l), matrix metalloproteinase-9, and blood coagulation factor v; the inhibition of fibrinolysis; the disruption of nitric oxide metabolism; and the increase in platelet reactivity and lipid peroxidation. |
2016-06-27 |
2023-08-13 |
Not clear |
Erkan Sukuroglu, Güliz N Güncü, Kamer Kilinc, Feriha Caglaya. Using Salivary Nitrite and Nitrate Levels as a Biomarker for Drug-Induced Gingival Overgrowth. Frontiers in cellular and infection microbiology. vol 5. 2016-06-22. PMID:26649282. |
it has been suggested that nitric oxide (no) might play a role in the pathogenesis of drug-induced gingival overgrowth due to the contribution of no to immune response and matrix degradation. |
2016-06-22 |
2023-08-13 |
Not clear |
Andreia P Oliveira, Alexandre Lobo-da-Cunha, Marcos Taveira, Marta Ferreira, Patrícia Valentão, Paula B Andrad. Digestive Gland from Aplysia depilans Gmelin: Leads for Inflammation Treatment. Molecules (Basel, Switzerland). vol 20. issue 9. 2016-06-08. PMID:26343629. |
regarding the anti-inflammatory potential in raw 264.7 cells stimulated with lipopolysaccharide, it was observed that this matrix has capacity to reduce nitric oxide (no) and l-citrulline levels, which suggests that its compounds may act by interference with inducible nitric oxide synthase. |
2016-06-08 |
2023-08-13 |
human |