| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bas Mj Olthof, Dominika Lyzwa, Sarah E Gartside, Adrian Ree. Nitric oxide signalling underlies salicylate-induced increases in neuronal firing in the inferior colliculus: A central mechanism of tinnitus?: NO dependence of salicylate effects in IC. Hearing research. vol 424. 2022-08-04. PMID:35926306. |
our data indicate that systemic salicylate induces neuronal hyperactivity in the auditory midbrain via a mechanism outside the inferior colliculus, presumably upstream in the auditory pathway; and that the mechanism is ultimately dependent on nitric oxide signalling within the inferior colliculus. |
2022-08-04 |
2023-08-14 |
Not clear |
| Vagdevi Hangarakatte Ramachandra, Senthilkumar Sivanesan, Anand Koppal, Shanmugam Anandakumar, Matthew D Howell, Ethirajan Sukumar, Rajagopalan Vijayaraghava. Embelin and levodopa combination therapy for improved Parkinson's disease treatment. Translational neuroscience. vol 13. issue 1. 2022-07-20. PMID:35855085. |
at the end of experimentation, the mice were sacrificed and the midbrain was used to evaluate various biochemical parameters, such as nitric oxide, peroxynitrite, urea, and lipid peroxidation. |
2022-07-20 |
2023-08-14 |
mouse |
| Sarah E Gartside, Abdurrahman Ercan Yurttaser, Amy L Burns, Nebojša Jovanović, Katie J Smith, Nana Shika Amegashiti, Bas M J Oltho. A role for nitric oxide in serotonin neurons of the midbrain raphe nuclei. The European journal of neuroscience. vol 51. issue 9. 2021-06-21. PMID:32115781. |
a role for nitric oxide in serotonin neurons of the midbrain raphe nuclei. |
2021-06-21 |
2023-08-13 |
rat |
| Meng-Meng Li, Ping Zhou, Xiao-Dong Chen, Huai-Sha Xu, Jun Wang, Ling Chen, Ning Zhang, Na Li. NO in the dPAG modulates panic-like responses and ASIC1a expression in the prefrontal cortex and hippocampus in mice. Biochemical and biophysical research communications. vol 511. issue 2. 2019-12-23. PMID:30770101. |
our previous study has demonstrated that the nitric oxide (no) pathway and the acid-sensing ion channel 1a (asic1a) level in the dorsal midbrain periaqueductal gray (dpag) are involved in the modulation of panic-like responses. |
2019-12-23 |
2023-08-13 |
mouse |
| Kavina Ganapathy, Indrani Datta, Ramesh Bhond. Astrocyte-Like Cells Differentiated from Dental Pulp Stem Cells Protect Dopaminergic Neurons Against 6-Hydroxydopamine Toxicity. Molecular neurobiology. vol 56. issue 6. 2019-08-29. PMID:30327976. |
when nitric oxide (no) release was inhibited by l-name in primary midbrain culture, bdnf release in co-culture under 6-ohda stress reduced further in naïve dpscs than in astrocyte-differentiated dpscs, suggesting that bdnf release in naïve dpscs is primarily regulated by paracrine signaling while for differentiated dpscs, it is equally through autocrine and paracrine signaling with no being the mediator. |
2019-08-29 |
2023-08-13 |
Not clear |
| Yasser A Khadrawy, Ahmed M Salem, Karima A El-Shamy, Emad K Ahmed, Nevein N Fadl, Eman N Hosn. Neuroprotective and Therapeutic Effect of Caffeine on the Rat Model of Parkinson's Disease Induced by Rotenone. Journal of dietary supplements. vol 14. issue 5. 2017-04-05. PMID:28301304. |
the data revealed a state of oxidative and nitrosative stress in the midbrain and the striatum of animal model of pd as indicated from the increased lipid peroxidation and nitric oxide levels and the decreased reduced glutathione level and activities of glutathione-s-transferase and superoxide dismutase. |
2017-04-05 |
2023-08-13 |
rat |
| H Hassanpour, Z Nikoukar, L Nasiri, S Bahadora. Differential gene expression of three nitric oxide synthases is consistent with increased nitric oxide in the hindbrain of broilers with cold-induced pulmonary hypertension. British poultry science. vol 56. issue 4. 2016-05-11. PMID:26053227. |
quantitative real-time pcr and griess reaction were conducted to evaluate gene expression of nitric oxide synthases (enos, nnos and inos) and nitric oxide (no) production in the hindbrain, midbrain, forebrain of chickens with cold-induced pulmonary hypertension. |
2016-05-11 |
2023-08-13 |
Not clear |
| Kana Kiyofuji, Yuki Kurauchi, Akinori Hisatsune, Takahiro Seki, Satoshi Mishima, Hiroshi Katsuk. A natural compound macelignan protects midbrain dopaminergic neurons from inflammatory degeneration via microglial arginase-1 expression. European journal of pharmacology. vol 760. 2016-03-08. PMID:25917324. |
treatment of midbrain slice cultures with interferon (ifn)-γ and lipopolysaccharide (lps) caused a substantial decrease in viable dopaminergic neurons and an increase in nitric oxide (no) production indicated by extracellular nitrite accumulation. |
2016-03-08 |
2023-08-13 |
Not clear |
| Yuki Kurauchi, Akinori Hisatsune, Yoichiro Isohama, Tomohiro Sawa, Takaaki Akaike, Koichi Shudo, Hiroshi Katsuk. Midbrain dopaminergic neurons utilize nitric oxide/cyclic GMP signaling to recruit ERK that links retinoic acid receptor stimulation to up-regulation of BDNF. Journal of neurochemistry. vol 116. issue 3. 2011-02-17. PMID:20649843. |
these results suggest that, by recruiting cyclic gmp and pkg, neuronal nitric oxide synthase-derived nitric oxide plays a novel and essential role in rar signaling leading to erk-dependent bdnf up-regulation in midbrain dopaminergic neurons. |
2011-02-17 |
2023-08-12 |
rat |
| Hiroshi Katsuki, Emi Kurimoto, Sachiko Takemori, Yuki Kurauchi, Akinori Hisatsune, Yoichiro Isohama, Yasuhiko Izumi, Toshiaki Kume, Koichi Shudo, Akinori Akaik. Retinoic acid receptor stimulation protects midbrain dopaminergic neurons from inflammatory degeneration via BDNF-mediated signaling. Journal of neurochemistry. vol 110. issue 2. 2009-07-31. PMID:19457078. |
am80 protected dopaminergic neurons in rat midbrain slice culture from injury mediated by lipopolysaccharide-activated microglia, without affecting production of nitric oxide, a key mediator of cell injury. |
2009-07-31 |
2023-08-12 |
mouse |
| Tarciso Tadeu Miguel, Ricardo Luiz Nunes-de-Souz. Anxiogenic-like effects induced by NMDA receptor activation are prevented by inhibition of neuronal nitric oxide synthase in the periaqueductal gray in mice. Brain research. vol 1240. 2009-02-17. PMID:18793618. |
these results suggest that intra-pag nitric oxide synthesis does not play a role on anxiety-like behavior elicited during epm exposure; however its synthesis is important for the proaversive effects produced by activation of glutamate-nmda receptors located within this limbic midbrain structure. |
2009-02-17 |
2023-08-12 |
mouse |
| Tarciso Tadeu Miguel, Ricardo Luiz Nunes-de-Souz. Anxiogenic-like effects induced by NMDA receptor activation are prevented by inhibition of neuronal nitric oxide synthase in the periaqueductal gray in mice. Brain research. vol 1240. 2009-02-17. PMID:18793618. |
jumping and running) and antinociception induced by intra-pag injection of n-methyl-d-aspartate (nmda) were completely blocked by prior infusion of n(omega)-propyl-l-arginine (npla), a specific neuronal nitric oxide synthesis (nnos) enzyme inhibitor, into the same midbrain structure. |
2009-02-17 |
2023-08-12 |
mouse |
| Fabrício A Moreira, Francisco S Guimarãe. Lack of effects of clomipramine on Fos and NADPH-diaphorase double-staining in the periaqueductal gray after exposure to an innate fear stimulus. Physiology & behavior. vol 94. issue 3. 2008-08-26. PMID:18321538. |
lack of effects of clomipramine on fos and nadph-diaphorase double-staining in the periaqueductal gray after exposure to an innate fear stimulus--nitric oxide (no) acts as a neurotransmitter in the rat dorsolateral periaqueductal gray (dlpag), a midbrain structure that modulates fear and defensive behavior. |
2008-08-26 |
2023-08-12 |
rat |
| Jihong Xing, De-Pei Li, Jianhua L. Role of GABA receptors in nitric oxide inhibition of dorsolateral periaqueductal gray neurons. Neuropharmacology. vol 54. issue 4. 2008-06-12. PMID:18222497. |
nitric oxide (no) affects neuronal activity of the midbrain periaqueductal gray (pag). |
2008-06-12 |
2023-08-12 |
Not clear |
| Dimitris E Emmanouil, Andrea S Dickens, Rick W Heckert, Yusuke Ohgami, Eunhee Chung, Shujie Han, Raymond M Quoc. Nitrous oxide-antinociception is mediated by opioid receptors and nitric oxide in the periaqueductal gray region of the midbrain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 3. 2008-05-22. PMID:17683915. |
nitrous oxide-antinociception is mediated by opioid receptors and nitric oxide in the periaqueductal gray region of the midbrain. |
2008-05-22 |
2023-08-12 |
mouse |
| Stephen Sammut, Kristina E Bray, Anthony R Wes. Dopamine D2 receptor-dependent modulation of striatal NO synthase activity. Psychopharmacology. vol 191. issue 3. 2007-06-12. PMID:17206493. |
striatal nitric oxide (no)-producing interneurons receive synaptic contacts from midbrain dopamine (da) neurons and are regulated by phasic da transmission. |
2007-06-12 |
2023-08-12 |
rat |
| Haruki Shibata, Hiroshi Katsuki, Mitsugi Okawara, Toshiaki Kume, Akinori Akaik. c-Jun N-terminal kinase inhibition and alpha-tocopherol protect midbrain dopaminergic neurons from interferon-gamma/lipopolysaccharide-induced injury without affecting nitric oxide production. Journal of neuroscience research. vol 83. issue 1. 2006-03-29. PMID:16307444. |
c-jun n-terminal kinase inhibition and alpha-tocopherol protect midbrain dopaminergic neurons from interferon-gamma/lipopolysaccharide-induced injury without affecting nitric oxide production. |
2006-03-29 |
2023-08-12 |
Not clear |
| Haruki Shibata, Hiroshi Katsuki, Mitsugi Okawara, Toshiaki Kume, Akinori Akaik. c-Jun N-terminal kinase inhibition and alpha-tocopherol protect midbrain dopaminergic neurons from interferon-gamma/lipopolysaccharide-induced injury without affecting nitric oxide production. Journal of neuroscience research. vol 83. issue 1. 2006-03-29. PMID:16307444. |
interferon-gamma (ifn-gamma)/lipopolysaccharide (lps) induces delayed dopaminergic neuron loss in midbrain slice cultures, because of nitric oxide production resulting from p38 mitogen-activated protein kinase (p38 mapk)-dependent induction of inducible nitric oxide synthase (inos). |
2006-03-29 |
2023-08-12 |
Not clear |
| Vanaja Paul, Leema Reddy, P Ekambara. A reversal by L-arginine and sodium nitroprusside of ageing-induced memory impairment in rats by increasing nitric oxide concentration in the hippocampus. Indian journal of physiology and pharmacology. vol 49. issue 2. 2005-11-03. PMID:16170986. |
the data were correlated with the activity of nitric oxide synthase (nos) and the concentration of nitric oxide (no) in the hippocampus, midbrain, cortex and cerebellum. |
2005-11-03 |
2023-08-12 |
rat |
| Santiago Canals, Maria José Casarejos, Sonsoles de Bernardo, Rosa Maria Solano, Maria Angeles Men. Selective and persistent activation of extracellular signal-regulated protein kinase by nitric oxide in glial cells induces neuronal degeneration in glutathione-depleted midbrain cultures. Molecular and cellular neurosciences. vol 24. issue 4. 2004-02-27. PMID:14697665. |
selective and persistent activation of extracellular signal-regulated protein kinase by nitric oxide in glial cells induces neuronal degeneration in glutathione-depleted midbrain cultures. |
2004-02-27 |
2023-08-12 |
Not clear |