All Relations between prefrontal cortex and serotonin

Reference Sentence Publish Date Extraction Date Species
Tetsuo Ono, Kodai Hino, Tomoko Kimura, Yasuhiro Uchimura, Takashi Ashihara, Takako Higa, Hideto Kojima, Takashi Murakami, Jun Udagaw. Excessive folic acid intake combined with undernutrition during gestation alters offspring behavior and brain monoamine profiles. Congenital anomalies vol issue 2022 35531602 these behavioral changes were accompanied by reduced dopamine in the prefrontal cortex (pfc), norepinephrine in the amygdala, and 5-hydroxytryptamine (5-ht) in the dorsal midbrain (dm), pfc, and amygdala where 5-ht neurons project from the dm. 2022-05-09 2022-05-12 Not clear
Tetsuo Ono, Kodai Hino, Tomoko Kimura, Yasuhiro Uchimura, Takashi Ashihara, Takako Higa, Hideto Kojima, Takashi Murakami, Jun Udagaw. Excessive folic acid intake combined with undernutrition during gestation alters offspring behavior and brain monoamine profiles. Congenital anomalies vol issue 2022 35531602 canonical discriminant analysis, including dopamine and dopac concentrations in the pfc, norepinephrine concentrations in the pfc, amygdala, and pons, and 5-ht and 5-hiaa concentrations in the amygdala and dm, correctly classified 73.5% of the offspring in con, ff, un, and un-ff groups. 2022-05-09 2022-05-12 Not clear
Sharonda S Harris, Sara M Green, Mayank Kumar, Nikhil M Ur. A role for cortical dopamine in the paradoxical calming effects of psychostimulants. Scientific reports vol 12 issue 1 2022 35210489 our ex vivo efflux experiments reveal that the ne transporter (net) blocker desipramine elevates both norepinephrine (ne) and dopamine (da), but not 5-ht levels, in pfc tissue slices from wild-type (wt) and dat-ko, but not net-ko mice. 2022-03-21 2022-02-27 Not clear
Sharonda S Harris, Sara M Green, Mayank Kumar, Nikhil M Ur. A role for cortical dopamine in the paradoxical calming effects of psychostimulants. Scientific reports vol 12 issue 1 2022 35210489 together, these data suggest elevation of pfc da and not ne or 5-ht, as a convergent mechanism for the paradoxical effects of psychostimulants observed in adhd therapy. 2022-03-21 2022-02-27 Not clear
Sharonda S Harris, Sara M Green, Mayank Kumar, Nikhil M Ur. A role for cortical dopamine in the paradoxical calming effects of psychostimulants. Scientific reports vol 12 issue 1 2022 35210489 our ex vivo efflux experiments reveal that the ne transporter (net) blocker desipramine elevates both norepinephrine (ne) and dopamine (da), but not 5-ht levels, in pfc tissue slices from wild-type (wt) and dat-ko, but not net-ko mice. 2022-02-25 2022-02-27 Not clear
Sharonda S Harris, Sara M Green, Mayank Kumar, Nikhil M Ur. A role for cortical dopamine in the paradoxical calming effects of psychostimulants. Scientific reports vol 12 issue 1 2022 35210489 together, these data suggest elevation of pfc da and not ne or 5-ht, as a convergent mechanism for the paradoxical effects of psychostimulants observed in adhd therapy. 2022-02-25 2022-02-27 Not clear
Tabinda Salman, Rushda Afroz, Shazia Nawaz, Khalid Mahmood, Darakhshan J Haleem, Shamshad Zarin. Differential effects of memory enhancing and impairing doses of methylphenidate on serotonin metabolism and 5-HT1A, GABA, glutamate receptor expression in the rat prefrontal cortex. Biochimie vol 191 issue 2021 34454977 animals showing improved performance had high 5-ht metabolism in the pfc while these levels were not affected in the group treated with higher mpd doses and exhibiting impaired memory. 2022-02-04 2022-01-14 Not clear
Mengge Bai, Heming Yu, Chong Chen, Xingzhe Xu, Yong He, Yue Wang, Yu Tian, Zhonghao Wu, Tianlan Lan, Yan Li, Xiangyu Chen, Zhi Chen, Libo Zhao, Liang Fang, Deyu Yang, Ke Cheng, Peng Xi. Pigment epithelium-derived factor may induce antidepressant phenotypes in mice by the prefrontal cortex. Neuroscience letters vol issue 2021 34965441 we detected pfc metabolite levels by liquid chromatography-tandem mass spectrometry and found significant upregulation of 5-hydroxyindoleacetic acid, kynurenine, 5-hydroxytryptamine, ornithine and glutamine, and downregulation of 5-hydroxytryptophan, glutamic acid and aspartic acid in pedf-overexpressing mice compared with control mice, in which no such changes were detected. 2022-01-26 2022-01-13 Not clear
Mengge Bai, Heming Yu, Chong Chen, Xingzhe Xu, Yong He, Yue Wang, Yu Tian, Zhonghao Wu, Tianlan Lan, Yan Li, Xiangyu Chen, Zhi Chen, Libo Zhao, Liang Fang, Deyu Yang, Ke Cheng, Peng Xi. Pigment epithelium-derived factor may induce antidepressant phenotypes in mice by the prefrontal cortex. Neuroscience letters vol issue 2021 34965441 we detected pfc metabolite levels by liquid chromatography-tandem mass spectrometry and found significant upregulation of 5-hydroxyindoleacetic acid, kynurenine, 5-hydroxytryptamine, ornithine and glutamine, and downregulation of 5-hydroxytryptophan, glutamic acid and aspartic acid in pedf-overexpressing mice compared with control mice, in which no such changes were detected. 2021-12-29 2022-01-13 Not clear
Mo Xian Chen, Shu Cheng, Lei Lei, Xiao Fan Zhang, Qiang Liu, Aijin Lin, Chloe U Wallis, Michael James Lukowicz, Pak C Sham, Qi Li, Li Juan A. The effects of maternal SSRI exposure on the serotonin system, prefrontal protein expression and behavioral development in male and female offspring rats. Neurochemistry international vol 146 issue 2021 33836218 moreover, down-regulation of 5-ht and sert expression were identified in the pfc. 2021-12-15 2022-01-13 Not clear
Tabinda Salman, Rushda Afroz, Shazia Nawaz, Khalid Mahmood, Darakhshan J Haleem, Shamshad Zarin. Differential effects of memory enhancing and impairing doses of methylphenidate on serotonin metabolism and 5-HT1A, GABA, glutamate receptor expression in the rat prefrontal cortex. Biochimie vol 191 issue 2021 34454977 animals showing improved performance had high 5-ht metabolism in the pfc while these levels were not affected in the group treated with higher mpd doses and exhibiting impaired memory. 2021-11-29 2022-01-14 Not clear
Hakimeh Saadati, Farshid Sadegzadeh, Nona Sakhaie, Hamdollah Panahpour, Mohsen Sagh. Serotonin depletion during the postnatal developmental period causes behavioral and cognitive alterations and decreases BDNF level in the brain of rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience vol 81 issue 2 2021 33404066 therefore, in the present study, we examined the effects of postnatal days (pnd 10-20) administration of para-chlorophenylalanine (pcpa, 100\xc2\xa0mg/kg, s.c) a 5-ht synthesis inhibitor, on anxiety-related behaviors, pain sensitivity, short-term recognition memory, and hippocampal and prefrontal cortex (pfc) brain-derived neurotrophic factor (bdnf) mrna expression in adult male and female rats. 2021-11-18 2022-01-13 Not clear
Xiao-Ju Liu, Hai-Juan Wang, Xiao-Yu Wang, Yin-Xia Ning, Jie Ga. GABABR1 in DRN mediated GABA to regulate 5-HT expression in multiple brain regions in male rats with high and low aggressive behavior. Neurochemistry international vol 150 issue 2021 34509561 on this basis, gaba content in the drn and 5-ht contents in the pfc, hypothalamus, hippocampus and drn were detected using elisa. 2021-11-11 2022-01-13 Not clear
Xiao-Ju Liu, Hai-Juan Wang, Xiao-Yu Wang, Yin-Xia Ning, Jie Ga. GABABR1 in DRN mediated GABA to regulate 5-HT expression in multiple brain regions in male rats with high and low aggressive behavior. Neurochemistry international vol 150 issue 2021 34509561 changes in 5-ht levels in the pfc, hypothalamus and hippocampus were detected afterward. 2021-11-11 2022-01-13 Not clear
Xiao-Ju Liu, Hai-Juan Wang, Xiao-Yu Wang, Yin-Xia Ning, Jie Ga. GABABR1 in DRN mediated GABA to regulate 5-HT expression in multiple brain regions in male rats with high and low aggressive behavior. Neurochemistry international vol 150 issue 2021 34509561 the contents of 5-ht in the pfc, hypothalamus and hippocampus of rats with high and low aggressive behavior (no difference between the two groups) were significantly decreased, but the change in gaba content in the drn was the opposite. 2021-11-11 2022-01-13 Not clear
Xiao-Ju Liu, Hai-Juan Wang, Xiao-Yu Wang, Yin-Xia Ning, Jie Ga. GABABR1 in DRN mediated GABA to regulate 5-HT expression in multiple brain regions in male rats with high and low aggressive behavior. Neurochemistry international vol 150 issue 2021 34509561 after microinjection of baclofen into the drn, the 5-ht contents in the pfc, hypothalamus and hippocampus of rats in each group decreased significantly. 2021-11-11 2022-01-13 Not clear
Xiao-Ju Liu, Hai-Juan Wang, Xiao-Yu Wang, Yin-Xia Ning, Jie Ga. GABABR1 in DRN mediated GABA to regulate 5-HT expression in multiple brain regions in male rats with high and low aggressive behavior. Neurochemistry international vol 150 issue 2021 34509561 in contrast, the 5-ht contents in the pfc, hypothalamus and hippocampus of rats in each group increased significantly after injection with cgp35348. 2021-11-11 2022-01-13 Not clear
Xiao-Ju Liu, Hai-Juan Wang, Xiao-Yu Wang, Yin-Xia Ning, Jie Ga. GABABR1 in DRN mediated GABA to regulate 5-HT expression in multiple brain regions in male rats with high and low aggressive behavior. Neurochemistry international vol 150 issue 2021 34509561 the significant increase in gaba in the drn combined with the significant increase in gb1 in the drn further mediated the synaptic inhibition effect, which reduced the 5-ht level of 5-ht neurons in the drn, resulting in a significant decrease in 5-ht levels in the pfc, hypothalamus and hippocampus. 2021-11-11 2022-01-13 Not clear
Xiao-Ju Liu, Hai-Juan Wang, Xiao-Yu Wang, Yin-Xia Ning, Jie Ga. GABABR1 in DRN mediated GABA to regulate 5-HT expression in multiple brain regions in male rats with high and low aggressive behavior. Neurochemistry international vol 150 issue 2021 34509561 therefore, gb1-mediated gaba regulation of 5-ht levels in the pfc, hypothalamus and hippocampus is one of the mechanisms of highly and less aggressive behavior originating in the drn. 2021-11-11 2022-01-13 Not clear
Ning Jiang, Lv Jingwei, Haixia Wang, Hong Huang, Qiong Wang, Guirong Zeng, Shanshan Li, Xinmin Li. Ginsenoside 20(S)-protopanaxadiol attenuates depressive-like behaviour and neuroinflammation in chronic unpredictable mild stress-induced depressive rats. Behavioural brain research vol 393 issue 2021 32464121 in addition, ppd decreased the elevated levels of cort and proinflammatory cytokines (il-6, il-1\xce\xb2 and tnf-\xce\xb1) in the serum and neurotransmitters (5-ht and ne) in the hippocampus and pfc induced by cums. 2021-10-04 2022-01-13 Not clear
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