All Relations between spinal cord posterior horn and nitrogen monoxide

Reference Sentence Publish Date Extraction Date Species
Lian-Zhi Cheng, Jia-Mei Zhou, Jun-Long Ma, Fan-Jing Wang, Kai Cheng, Qian Chen, Hui-Lun Yuan, Ai-Juan Jian. [Tetrahydropalmatine alleviated diabetic neuropathic pain by inhibiting activation of microglia via p38 MAPK signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica vol 47 issue 9 2022 35531701 the protein expression levels of ox42, inducible nitric oxide synthase(inos), cd206, p38, and p-p38 were determined by western blot, the fluorescence expression levels of ox42 and p-p38 in the dorsal horn of the rat spinal cord by immunofluorescence, the mrna content of p38 and ox42 in rat spinal cord tissue by qrt-pcr, and levels of nitric oxide(no), interleukin-1\xce\xb2(il-1\xce\xb2), interleukin-6(il-6), tumor necrosis factor-\xce\xb1(tnf-\xce\xb1), interleukin-10(il-10), and serum fasting insulin(fins) by enzyme-linked immunosorbent assay(elisa). 2022-05-09 2022-05-12 Not clear
Yuanyuan Ding, Peng Yao, Tao Hong, Zhenkai Han, Baisong Zhao, Weimin Chen, Guangyu Zho. Early hyperbaric oxygen effects on neuropathic pain and nitric oxide synthase isoforms in CCI rats. Oncotarget vol 9 issue 7 2019 29484128 we observed the effects of early use of 2.5 absolute atmosphere (ata) hbo on neuropathic pain-related behaviors and the expression of nitric oxide synthase (nos) isoforms in the spinal dorsal horn. 2019-11-20 2022-01-13 Not clear
Sheu-Ran Choi, Dae-Hyun Roh, Seo-Yeon Yoon, Hoon-Seong Choi, Suk-Yun Kang, Ho-Jae Han, Alvin James Beitz, Jang-Hern Le. Astrocyte D-serine modulates the activation of neuronal NOS leading to the development of mechanical allodynia in peripheral neuropathy. Molecular pain vol 15 issue 2019 30900515 intrathecal administration of the serine racemase inhibitor, l-serine o-sulfate potassium salt (lsos) or the d-serine degrading enzyme, d-amino acid oxidase (daao) on post-operative days 0-3 significantly reduced the cci-induced increase in nitric oxide (no) levels and nicotinamide adenine dinucleotide phosphate-diaphorase staining in lumbar dorsal horn neurons, as well as the cci-induced decrease in phosphorylation (ser847) of nnos (pnnos) on day 3 post-cci surgery. 2019-08-12 2022-01-13 Not clear
Lu Yang, Sai-Hua Wang, Yan Hu, Yan-Fang Sui, Tao Peng, Tie-Cheng Gu. Effects of Repetitive Transcranial Magnetic Stimulation on Astrocytes Proliferation and nNOS Expression in Neuropathic Pain Rats. Current medical science vol 38 issue 3 2018 30074216 the behavior of rats with experimental chronic neuropathic pain was observed, and the expression of neuronal nitric oxide synthase (nnos) in the ipsilateral dorsal root ganglions (drgs) and the activation and proliferation of astrocytes in the ipsilateral spinal dorsal horn were detected. 2018-11-02 2022-01-13 Not clear
Yuanyuan Ding, Peng Yao, Tao Hong, Hongxi Li, Yongqiang Zhu, Zhenkai Han, Guangyu Zho. The analgesic effect of early hyperbaric oxygen treatment in chronic constriction injury rats and its influence on nNOS and iNOS expression and inflammatory factor production. Molecular pain vol 14 issue 2018 29592784 also, astrocytes at the dorsal horn were activated, the synaptic structure was disordered, the expressions of inducible nitric oxide synthase and neuronal nitric oxide synthase were increased significantly, and the release of inflammatory factor (tnf-\xce\xb1 and il-1\xce\xb2) was up-regulated. 2018-10-22 2022-01-13 Not clear
Yuanyuan Ding, Peng Yao, Tao Hong, Hongxi Li, Yongqiang Zhu, Zhenkai Han, Guangyu Zho. The analgesic effect of early hyperbaric oxygen treatment in chronic constriction injury rats and its influence on nNOS and iNOS expression and inflammatory factor production. Molecular pain vol 14 issue 2018 29592784 the expressions of inducible nitric oxide synthase and neuronal nitric oxide synthase were decreased in the dorsal horn, and the release of inflammatory factor (tnf-\xce\xb1 and il-1\xce\xb2) was reduced. 2018-10-22 2022-01-13 Not clear
Shao-Rui Chen, Xiao-Gao Jin, Hui-Lin Pa. Endogenous nitric oxide inhibits spinal NMDA receptor activity and pain hypersensitivity induced by nerve injury. Neuropharmacology vol 125 issue 2018 28754372 inhibition of neuronal nitric oxide synthase (nnos) or blocking the s-nitrosylation reaction with n-ethylmaleimide abolished the inhibitory effects of l-arginine on nmda receptor currents recorded from spinal dorsal horn neurons in sham control and nerve-injured rats. 2018-06-12 2022-01-14 Not clear
Dongmei Wang, Yaping Xue, Yanhua Yan, Minjie Lin, Jiajia Yang, Jianzhong Huang, Yanguo Hon. Reversal of neurochemical alterations in the spinal dorsal horn and dorsal root ganglia by Mas-related gene (Mrg) receptors in a rat model of spinal nerve injury. Neurobiology of disease vol 91 issue 2018 27018398 bam8-22 (10nmol) inhibited snl-induced upregulation of neuronal nitric oxide synthesis (nnos) and phosphorylation of cyclic amp response element-binding protein (p-creb) in the spinal dorsal horn. 2018-02-20 2022-01-12 Not clear
Jos\\xc3\\xa9 Mar\\xc3\\xada Flores Ramos, Laurent Devoize, Am\\xc3\\xa9lie Descheemaeker, Jean-Louis Molat, Philippe Luccarini, Radhouane Dalle. The nitric oxide donor, isosorbide dinitrate, induces a cephalic cutaneous hypersensitivity, associated with sensitization of the medullary dorsal horn. Neuroscience vol 344 issue 2017 28057535 the nitric oxide donor, isosorbide dinitrate, induces a cephalic cutaneous hypersensitivity, associated with sensitization of the medullary dorsal horn. 2017-11-09 2022-01-13 Not clear
Jos\\xc3\\xa9 Mar\\xc3\\xada Flores Ramos, Laurent Devoize, Am\\xc3\\xa9lie Descheemaeker, Jean-Louis Molat, Philippe Luccarini, Radhouane Dalle. The nitric oxide donor, isosorbide dinitrate, induces a cephalic cutaneous hypersensitivity, associated with sensitization of the medullary dorsal horn. Neuroscience vol 344 issue 2017 28057535 combining behavioral, immunohistochemical, and in vivo electrophysiological approaches, this study investigated the effect of systemic administration of the nitric oxide donor, isosorbide dinitrate (isdn), on cephalic and extracephalic cutaneous sensitivity and on neuronal activation within the medullary dorsal horn (mdh) in the rat. 2017-11-09 2022-01-13 Not clear
Wei Hu, Yan Zhang, Qiaoyan Cai, Dongmei Wang, Yanguo Hon. Blockade of 5-HT2A receptors at the site of inflammation inhibits activation of spinal dorsal horn neurons in rats. Brain research bulletin vol 124 issue 2017 27040714 treatment with the 5-ht2a receptor antagonist ketanserin (20\xce\xbcg) in the hindpaw following intraplantar injection of carrageenan inhibited the increase in nicotinamide adenine dinucleotide phosphate-diaphorase (nadph-d) reactivity, a marker of nitric oxide synthase (nos), in the spinal dorsal horn. 2017-10-26 2022-01-12 Not clear
Nan-Fu Chen, Shi-Ying Huang, Ching-Hsiang Lu, Chun-Lin Chen, Chien-Wei Feng, Chun-Hong Chen, Han-Chun Hung, Yen-You Lin, Ping-Jyun Sung, Chun-Sung Sung, San-Nan Yang, Hui-Min David Wang, Yu-Chia Chang, Jyh-Horng Sheu, Wu-Fu Chen, Zhi-Hong We. Flexibilide obtained from cultured soft coral has anti-neuroinflammatory and analgesic effects through the upregulation of spinal transforming growth factor-\\xce\\xb21 in neuropathic rats. Marine drugs vol 12 issue 7 2015 24979268 flexibilide significantly inhibited cci-induced activation of microglia and astrocytes, as well as the upregulated proinflammatory enzyme, inducible nitric oxide synthase, in the ipsilateral spinal dorsal horn. 2015-10-12 2022-01-12 Not clear
Wei Chen, Xu-Dong Zhang, Zhuo-Hui Lu, Deng-Ming We. [Effect of triptolide on iNOS and SP expressions in spinal dorsal horn and dorsal root ganglion of rats with adjuvant arthritis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica vol 39 issue 9 2014 25095383 to observe the analgesic effect of triptolide (tp) of high, middle and low doses on rats with adjuvant arthritis (aa), and the expressions of inducible nitric oxide synthase (inos) and substance p (sp) in spinal dorsal horn and dorsal root ganglion (drg) of corresponding sections, in order to discuss the possible mechanism for the analgesic effect of tp on rats with adjuvant arthritis. 2014-10-30 2022-01-12 Not clear
Tong-nan Li, Qing-jun Li, Wen-bin Li, Xiao-cai Sun, Shu-qin L. [Effect of CGRP receptor antagonist CGRP8-37 on nociceptive response, NOS expression and NO content in the dorsal horn of spinal cord during formalin-induced inflammatory pain in rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology vol 20 issue 3 2012 21192428 to study the effect of cgrp receptor antagonist cgrp8-37 on nociceptive response and expression of nitric oxide synthase (nos) and content of nitric oxide (no) in the dorsal horn of the spinal cord of rats during formalin-induced inflammatory pain. 2012-12-07 2022-01-12 Not clear
Yara Cury, Gisele Picolo, Vanessa Pacciari Gutierrez, Sergio Henrique Ferreir. Pain and analgesia: The dual effect of nitric oxide in the nociceptive system. Nitric oxide : biology and chemistry vol 25 issue 3 2012 21723953 nitric oxide is an important neurotransmitter involved in the nociceptive process and, in the dorsal horn of the spinal cord, it contributes to the development of central sensitization. 2012-06-29 2022-01-12 Not clear
Gui-He Zhang, Miao-Miao Lv, Shuang Wang, Lei Chen, Nian-Song Qian, Yu Tang, Xu-Dong Zhang, Peng-Cheng Ren, Chang-Jun Gao, Xu-De Sun, Li-Xian X. Spinal astrocytic activation is involved in a virally-induced rat model of neuropathic pain. PloS one vol 6 issue 9 2012 21969850 results showed that nitric oxide (no) produced by inducible nitric oxide synthase mediated the development of spinal astrocytic activation, and activated astrocytes dramatically increased interleukin-1\xce\xb2 expression which induced n-methyl-d-aspartic acid receptor (nmdar) phosphorylation in spinal dorsal horn neurons to strengthen pain transmission. 2012-04-13 2022-01-12 Not clear
T C P Sardella, E Polg\\xc3\\xa1r, M Watanabe, A J Tod. A quantitative study of neuronal nitric oxide synthase expression in laminae I-III of the rat spinal dorsal horn. Neuroscience vol 192 issue 2012 21763759 a quantitative study of neuronal nitric oxide synthase expression in laminae i-iii of the rat spinal dorsal horn. 2012-01-18 2022-01-12 Not clear
Bruce Mesnage, St\\xc3\\xa9phane Gaillard, Antoine G Godin, Jean-Luc Rodeau, Matthieu Hammer, Jakob Von Engelhardt, Paul W Wiseman, Yves De Koninck, R\\xc3\\xa9my Schlichter, Matilde Cordero-Erausqui. Morphological and functional characterization of cholinergic interneurons in the dorsal horn of the mouse spinal cord. The Journal of comparative neurology vol 519 issue 16 2012 21618225 in addition, immunostainings demonstrated that dorsal horn cholinergic interneurons in the mouse are \xce\xb3-aminobutyric acidergic and express nitric oxide synthase, as in rats. 2012-01-05 2022-01-12 Not clear
Xiao-Gao Jin, Shao-Rui Chen, Xue-Hong Cao, Li Li, Hui-Lin Pa. Nitric oxide inhibits nociceptive transmission by differentially regulating glutamate and glycine release to spinal dorsal horn neurons. The Journal of biological chemistry vol 286 issue 38 2011 21813646 nitric oxide inhibits nociceptive transmission by differentially regulating glutamate and glycine release to spinal dorsal horn neurons. 2011-11-23 2022-01-12 Not clear
Dongmei Wang, Peiwen Chen, Qi Li, R\\xc3\\xa9mi Quirion, Yanguo Hon. Blockade of adrenomedullin receptors reverses morphine tolerance and its neurochemical mechanisms. Behavioural brain research vol 221 issue 1 2011 21382419 administration of am(22-52) at a dose of 35.8 \xce\xbcg reversed the morphine induced-enhancement of nnos (neuronal nitric oxide synthase) and cgrp immunoreactivity in the spinal dorsal horn and/or dorsal root ganglia (drg). 2011-09-06 2022-01-12 Not clear
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