| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexander G Zestos, Harmain Rafi, Negar G Ardabil. Carbon Fiber Multielectrode Arrays for Multiplexing Neurotransmitter Detection in Heterogeneous Brain Regions. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556754. |
we mapped out endogenous levels of neurochemicals such as dopamine, serotonin, and adenosine in regions including the ventral tegmental area, caudate putamen, raphe nuclei, and substantia nigra. |
2022-05-13 |
2023-08-13 |
mouse |
| Xing Cai, Hailan Liu, Bing Feng, Meng Yu, Yang He, Hesong Liu, Chen Liang, Yongjie Yang, Longlong Tu, Nan Zhang, Lina Wang, Na Yin, Junying Han, Zili Yan, Chunmei Wang, Pingwen Xu, Qi Wu, Qingchun Tong, Yanlin He, Yong X. A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice. Nature neuroscience. 2022-05-02. PMID:35501380. |
in this study, we found that da neurons in the mouse ventral tegmental area bidirectionally regulate the activity of 5-ht neurons in the dorsal raphe nucleus (drn), with weaker stimulation causing drd2-dependent inhibition and overeating, while stronger stimulation causing drd1-dependent activation and anorexia. |
2022-05-02 |
2023-08-13 |
mouse |
| Hector Vargas-Perez, Taryn Elizabeth Grieder, Derek van der Koo. Neural Plasticity in the Ventral Tegmental Area, Aversive Motivation during Drug Withdrawal and Hallucinogenic Therapy. Journal of psychoactive drugs. 2022-02-04. PMID:35114904. |
recent studies point out that serotonin (5-hydroxytryptamine, 5-ht) receptors, especially the 2a (5-ht2a) subtype, play an important role in bdnf-related neural plasticity in the vta. |
2022-02-04 |
2023-08-13 |
Not clear |
| Kristina Csatlosova, Eszter Bogi, Barbora Durisova, Daniil Grinchii, Ruslan Paliokha, Lucia Moravcikova, Lubica Lacinova, Daniela Jezova, Eliyahu Dremenco. Maternal immune activation in rats attenuates the excitability of monoamine-secreting neurons in adult offspring in a sex-specific way. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 43. 2021-11-19. PMID:33341344. |
during days 53-63 postpartum, rats were anesthetized and electrodes were inserted into the dorsal raphe nucleus, locus coeruleus, and ventral tegmental area for in vivo excitability assessment of 5-ht, noradrenaline, and dopamine neurons. |
2021-11-19 |
2023-08-13 |
rat |
| Seong W Kan. Central Nervous System Associated With Light Perception and Physiological Responses of Birds. Frontiers in physiology. vol 12. 2021-11-10. PMID:34744764. |
although further research is required to establish the functional role of opn4 in the ventral tegmental area (vta), dorsal raphe nucleus, and caudal raphe nucleus in the light perception and physiological responses of birds, it is an exciting prospect because the previous results in birds support this hypothesis that opn4 in the midbrain da and serotonin neurons may play significant roles on the light-induced welfare of birds. |
2021-11-10 |
2023-08-13 |
Not clear |
| Zahra Ghasemzadeh, Masoud Seddighfar, Sakineh Alijanpour, Ameneh Rezayo. Ventral tegmental area serotonin 5-HT Physiology & behavior. vol 239. 2021-10-20. PMID:34242672. |
ventral tegmental area serotonin 5-ht the present study examined the role of ventral tegmental area (vta) serotonergic 5ht |
2021-10-20 |
2023-08-13 |
Not clear |
| Xiaohong Huang, Shihuan Kuang, Todd J Applegate, Tsang-Long Lin, Heng-Wei Chen. Prenatal Serotonin Fluctuation Affects Serotoninergic Development and Related Neural Circuits in Chicken Embryos. Neuroscience. vol 473. 2021-10-01. PMID:34425158. |
the comprehensive effect of 5-ht exposure was not dosage-dependent but the working pathways differed, 10 µg 5-ht exposure reduced 5-ht turnover rate, increased 5-ht 1a receptor expression, and facilitated the ventral tegmental area neuronal development; while 20 µg 5-ht exposure increased the serotoninergic and daergic neurotransmission and enhanced serotoninergic regulation to the hypothalamus. |
2021-10-01 |
2023-08-13 |
chicken |
| Kate Z Peters, Joseph F Cheer, Raffaella Tonin. Modulating the Neuromodulators: Dopamine, Serotonin, and the Endocannabinoid System. Trends in neurosciences. vol 44. issue 6. 2021-08-18. PMID:33674134. |
this view has been challenged by emerging evidence that 5-ht supports reward seeking via activation of da neurons in the ventral tegmental area. |
2021-08-18 |
2023-08-13 |
Not clear |
| Margherita Tassan Mazzocco, Fabrizia Claudia Guarnieri, Elena Monzani, Fabio Benfenati, Flavia Valtorta, Stefano Coma. Dysfunction of the serotonergic system in the brain of synapsin triple knockout mice is associated with behavioral abnormalities resembling synapsin-related human pathologies. Progress in neuro-psychopharmacology & biological psychiatry. vol 105. 2021-07-19. PMID:33058959. |
using in vivo electrophysiology, we recorded the spontaneous activity of dorsal raphe nucleus (drn) serotonin (5-ht) and ventral tegmental area (vta) dopamine (da) neurons. |
2021-07-19 |
2023-08-13 |
mouse |
| Margherita Tassan Mazzocco, Fabrizia Claudia Guarnieri, Elena Monzani, Fabio Benfenati, Flavia Valtorta, Stefano Coma. Dysfunction of the serotonergic system in the brain of synapsin triple knockout mice is associated with behavioral abnormalities resembling synapsin-related human pathologies. Progress in neuro-psychopharmacology & biological psychiatry. vol 105. 2021-07-19. PMID:33058959. |
behavioral dysfunctions were accompanied by reduced firing activity of drn 5-ht, but not vta da, neurons. |
2021-07-19 |
2023-08-13 |
mouse |
| Hicham Chatoui, Abdellatif Abbaoui, Omar El Hiba, Ahmed Draoui, Halima Gamran. Neurobehavioral and neurophysiological effects of prolonged osmotic stress in rats: A focus on anxiety state and pain perception. Journal of chemical neuroanatomy. vol 106. 2021-04-06. PMID:32334030. |
this study examined the effect of prolonged water deprivation, in rat, on 5-ht and th- immuno-expression in dorsal raphe nucleus (drn), substantia nigra pars compacta (snc), ventral tegmental area (vta), and magnus raphe nucleus (mrn). |
2021-04-06 |
2023-08-13 |
rat |
| Shunpei Moriya, Akira Yamashita, Daiki Masukawa, Yuki Kambe, Junichi Sakaguchi, Honami Setoyama, Akihiro Yamanaka, Tomoyuki Kuwak. Involvement of supralemniscal nucleus (B9) 5-HT neuronal system in nociceptive processing: a fiber photometry study. Molecular brain. vol 13. issue 1. 2021-02-12. PMID:32005128. |
in this study, we measured activities of b9 5-ht neuronal cell bodies and b9 5-ht neuron-derived axons located in the locus coeruleus (lc) and ventral tegmental area (vta), which are also main players of pain management, using fiber photometry system. |
2021-02-12 |
2023-08-13 |
mouse |
| Louis Monti, Michael R Liebowit. Neural circuits of anxiolytic and antidepressant CNS spectrums. 2020-12-11. PMID:33092667. |
alternatively, antidepressant pherines could facilitate the crh and gabaergic neurons that inhibit the release of nps from the lc, increase glutamate release from the bnst, and increase norepinephrine (ne), dopamine (da), and serotonin release from the lc, vta, and raphe nucleus, respectively. |
2020-12-11 |
2023-08-13 |
human |
| Tadashi Takada, Naoki Yoneda, Tetsushi Hirano, Kanoko Onaru, Youhei Mantani, Toshifumi Yokoyama, Hiroshi Kitagawa, Yoshiaki Tabuchi, Collins Nimako, Mayumi Ishizuka, Yoshinori Ikenaka, Nobuhiko Hosh. Combined exposure to dinotefuran and chronic mild stress counteracts the change of the emotional and monoaminergic neuronal activity induced by either exposure singly despite corticosterone elevation in mice. The Journal of veterinary medical science. vol 82. issue 3. 2020-11-16. PMID:31983702. |
in addition, serotonin (5-ht) and tryptophan hydroxylase 2 (tph2) of the dorsal raphe nuclei (drn) and median raphe nuclei (mrn) and tyrosine hydroxylase (th) of the ventral tegmental area and substantia nigra (sn) were evaluated immunohistochemically. |
2020-11-16 |
2023-08-13 |
mouse |
| Masoud Seddighfar, Zahra Ghasemzadeh, Ameneh Rezayo. The blockade of 5-HT Brain research. vol 1715. 2020-09-18. PMID:30898674. |
the blockade of 5-ht the aim of the present study was to determine the involvement of the vta 5-ht |
2020-09-18 |
2023-08-13 |
Not clear |
| Wen-Jun Zou, Yun-Long Song, Min-Yi Wu, Xiang-Tian Chen, Qiang-Long You, Qian Yang, Zheng-Yi Luo, Lang Huang, Yin Kong, Jing Feng, Dong-Xiang Fang, Xiao-Wen Li, Jian-Ming Yang, Lin Mei, Tian-Ming Ga. A discrete serotonergic circuit regulates vulnerability to social stress. Nature communications. vol 11. issue 1. 2020-09-14. PMID:32839452. |
we identified a distinct, anatomically and functionally defined serotonergic subpopulation in the dr that projects to the vta (5-ht |
2020-09-14 |
2023-08-13 |
Not clear |
| Blake A Kimmey, Alexey Ostroumov, John A Dan. 5-HT Proceedings of the National Academy of Sciences of the United States of America. 2020-06-06. PMID:31806759. |
5-ht stress is known to alter gabaergic signaling in the ventral tegmental area (vta), and this inhibitory plasticity is associated with increased alcohol self-administration. |
2020-06-06 |
2023-08-13 |
Not clear |
| Romana Koprdova, Kristina Csatlosova, Barbora Durisova, Eszter Bogi, Magdalena Majekova, Eliyahu Dremencov, Mojmir Mac. Electrophysiology and Behavioral Assessment of the New Molecule SMe1EC2M3 as a Representative of the Future Class of Triple Reuptake Inhibitors. Molecules (Basel, Switzerland). vol 24. issue 23. 2020-04-14. PMID:31757051. |
electrophysiological investigations showed that sme1ec2m3 dose-dependently suppressed the excitability of 5-ht neurons of the dorsal raphe nucleus (drn), norepinephrine neurons of the locus coeruleus (lc), and dopamine neurons of the ventral tegmental area (vta). |
2020-04-14 |
2023-08-13 |
Not clear |
| Hui-Ling Wang, Shiliang Zhang, Jia Qi, Huikun Wang, Roger Cachope, Carlos A Mejias-Aponte, Jorge A Gomez, Gabriel E Mateo-Semidey, Gerard M J Beaudoin, Carlos A Paladini, Joseph F Cheer, Marisela Morale. Dorsal Raphe Dual Serotonin-Glutamate Neurons Drive Reward by Establishing Excitatory Synapses on VTA Mesoaccumbens Dopamine Neurons. Cell reports. vol 26. issue 5. 2020-03-13. PMID:30699344. |
dorsal raphe (dr) serotonin neurons provide a major input to the ventral tegmental area (vta). |
2020-03-13 |
2023-08-13 |
Not clear |
| Hui-Ling Wang, Shiliang Zhang, Jia Qi, Huikun Wang, Roger Cachope, Carlos A Mejias-Aponte, Jorge A Gomez, Gabriel E Mateo-Semidey, Gerard M J Beaudoin, Carlos A Paladini, Joseph F Cheer, Marisela Morale. Dorsal Raphe Dual Serotonin-Glutamate Neurons Drive Reward by Establishing Excitatory Synapses on VTA Mesoaccumbens Dopamine Neurons. Cell reports. vol 26. issue 5. 2020-03-13. PMID:30699344. |
here, we show that dr serotonin transporter (sert) neurons establish both asymmetric and symmetric synapses on vta dopamine neurons, but most of these synapses are asymmetric. |
2020-03-13 |
2023-08-13 |
Not clear |