| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hans S Crombag, Jennifer M Bossert, Eisuke Koya, Yavin Shaha. Review. Context-induced relapse to drug seeking: a review. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 363. issue 1507. 2008-11-17. PMID:18640922. |
we then summarize results from pharmacological and neuroanatomical studies on the role of several neurotransmitter systems (dopamine, glutamate, serotonin and opioids) and brain areas (ventral tegmental area, accumbens shell, dorsal striatum, basolateral amygdala, prefrontal cortex, dorsal hippocampus and lateral hypothalamus) in context-induced reinstatement. |
2008-11-17 |
2023-08-12 |
rat |
| Xuesheng Li, Yun Zhang, Xia Zhan. Tat-3L4F does not significantly affect spatial learning and memory. Behavioural brain research. vol 193. issue 2. 2008-11-03. PMID:18571742. |
we recently found that the interfering peptide tat-3l4f is able not only to disrupt the protein-protein interaction of pten (phosphatase and tensin homologue deleted on chromosome 10) with the serotonin 5-ht2c receptor in the rat ventral tegmental area (vta) but also to suppress the conditioned place preference induced by cannabinoid and nicotine without significant effects on anxiety, feeding behavior and motor activity. |
2008-11-03 |
2023-08-12 |
rat |
| Bruno P Guiard, Mostafa El Mansari, Zul Merali, Pierre Blie. Functional interactions between dopamine, serotonin and norepinephrine neurons: an in-vivo electrophysiological study in rats with monoaminergic lesions. The international journal of neuropsychopharmacology. vol 11. issue 5. 2008-09-24. PMID:18205979. |
in contrast, the selective lesion of 5-ht neurons produced by 5,7-dihydroxytryptamine (5,7-dht) enhanced by 36% the firing activity of vta da neurons, thereby indicating an inhibitory effect of the 5-ht input on these da neurons. |
2008-09-24 |
2023-08-12 |
rat |
| E Shearman, S Fallon, H Sershen, A Lajth. Nicotine-induced monoamine neurotransmitter changes in the brain of young rats. Brain research bulletin. vol 76. issue 6. 2008-08-19. PMID:18598854. |
norepinephrine levels in the young were lower in all areas except in the vh where they were the same, and serotonin levels were lower except in the vta and ls where they remained the same, and higher in the naccs. |
2008-08-19 |
2023-08-12 |
rat |
| K Wedzony, A Chocyk, W Kolasiewicz, M Maćkowia. Glutamatergic neurons of rat medial prefrontal cortex innervating the ventral tegmental area are positive for serotonin 5-HT1A receptor protein. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 58. issue 4. 2008-04-24. PMID:18195476. |
glutamatergic neurons of rat medial prefrontal cortex innervating the ventral tegmental area are positive for serotonin 5-ht1a receptor protein. |
2008-04-24 |
2023-08-12 |
rat |
| K Wedzony, A Chocyk, W Kolasiewicz, M Maćkowia. Glutamatergic neurons of rat medial prefrontal cortex innervating the ventral tegmental area are positive for serotonin 5-HT1A receptor protein. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 58. issue 4. 2008-04-24. PMID:18195476. |
the present study was designed to investigate whether serotonin 5-ht1a receptor protein (5-ht1a receptor-immunoreactivity), is present on cortical pyramidal neurons of the rat medial prefrontal cortex (mpc) innervating the ventral tegmental area (vta). |
2008-04-24 |
2023-08-12 |
rat |
| K Wedzony, A Chocyk, W Kolasiewicz, M Maćkowia. Glutamatergic neurons of rat medial prefrontal cortex innervating the ventral tegmental area are positive for serotonin 5-HT1A receptor protein. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 58. issue 4. 2008-04-24. PMID:18195476. |
it was found that approximately 52% of cells in layers ii/iii of the mpc whose axons initial segments were immunoreactive for serotonin 5ht1a receptor were also labeled with fluoro-gold (fg), a retrograde tracer injected into the vta, indicating that certain portion of neurons forming glutamatergic innervations of the vta may be controlled by serotonin 5-ht1a receptors. |
2008-04-24 |
2023-08-12 |
rat |
| K Wedzony, A Chocyk, W Kolasiewicz, M Maćkowia. Glutamatergic neurons of rat medial prefrontal cortex innervating the ventral tegmental area are positive for serotonin 5-HT1A receptor protein. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 58. issue 4. 2008-04-24. PMID:18195476. |
these anatomical data indicate that serotonin 5-ht1a receptors might potentially control the excitability and propagation of information transmitted by the pyramidal cells to the vta. |
2008-04-24 |
2023-08-12 |
rat |
| K Wedzony, A Chocyk, W Kolasiewicz, M Maćkowia. Glutamatergic neurons of rat medial prefrontal cortex innervating the ventral tegmental area are positive for serotonin 5-HT1A receptor protein. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 58. issue 4. 2008-04-24. PMID:18195476. |
moreover, our results indicate that the drugs operating via serotonin 5-ht1a receptors in the mpc, might control from this level the release of glutamate in the vta and restore function of glutamate neurotransmission, whose dysfunction is observed for example in schizophrenia. |
2008-04-24 |
2023-08-12 |
rat |
| Stéphane Doly, Emmanuel Valjent, Vincent Setola, Jacques Callebert, Denis Hervé, Jean-Marie Launay, Luc Maroteau. Serotonin 5-HT2B receptors are required for 3,4-methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 11. 2008-04-08. PMID:18337424. |
here we show that acute pharmacological inhibition or genetic ablation of the 5-ht(2b) receptor in mice completely abolishes mdma-induced hyperlocomotion and 5-ht release in nucleus accumbens and ventral tegmental area. |
2008-04-08 |
2023-08-12 |
mouse |
| Zachary A Rodd, Scott M Oster, Zheng-Ming Ding, Jamie E Toalston, Gerald Deehan, Richard L Bell, Ting-Kai Li, William J McBrid. The reinforcing properties of salsolinol in the ventral tegmental area: evidence for regional heterogeneity and the involvement of serotonin and dopamine. Alcoholism, clinical and experimental research. vol 32. issue 2. 2008-03-26. PMID:18162075. |
the reinforcing properties of salsolinol in the ventral tegmental area: evidence for regional heterogeneity and the involvement of serotonin and dopamine. |
2008-03-26 |
2023-08-12 |
Not clear |
| Sylvia Navailles, Delphine Moison, Kathryn A Cunningham, Umberto Spampinat. Differential regulation of the mesoaccumbens dopamine circuit by serotonin2C receptors in the ventral tegmental area and the nucleus accumbens: an in vivo microdialysis study with cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 2. 2008-02-06. PMID:17429406. |
stimulation of central serotonin2c receptor (5-ht(2c)r) inhibits dopamine (da)-dependent neurochemical and behavioral effects of cocaine, while 5-ht(2c)rs locally expressed into the ventral tegmental area (vta) and the nucleus accumbens (nac) exert opposite functional control over cocaine-induced behavioral effects. |
2008-02-06 |
2023-08-12 |
rat |
| Sylvia Navailles, Delphine Moison, Kathryn A Cunningham, Umberto Spampinat. Differential regulation of the mesoaccumbens dopamine circuit by serotonin2C receptors in the ventral tegmental area and the nucleus accumbens: an in vivo microdialysis study with cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 2. 2008-02-06. PMID:17429406. |
using in vivo microdialysis in halothane-anesthetized rats, we tested the hypothesis that this functionally opposite regulation of the mesoaccumbens da pathway relies on the ability of 5-ht(2c)rs in the vta and the nac to inhibit and enhance respectively cocaine-induced accumbal da outflow. |
2008-02-06 |
2023-08-12 |
rat |
| Sylvia Navailles, Delphine Moison, Kathryn A Cunningham, Umberto Spampinat. Differential regulation of the mesoaccumbens dopamine circuit by serotonin2C receptors in the ventral tegmental area and the nucleus accumbens: an in vivo microdialysis study with cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 2. 2008-02-06. PMID:17429406. |
these results further support the idea that the overall action of central 5-ht(2c)rs on accumbal da output is dependent, at least in part, on the functional balance between different 5-ht(2c)r populations within the nac and within the mesoaccumbens da pathway (vta vs nac). |
2008-02-06 |
2023-08-12 |
rat |
| Ouissame Mnie-Filali, Lionel Dahan, Luc Zimmer, Nasser Haddjer. Effects of the serotonin 5-HT(7) receptor antagonist SB-269970 on the inhibition of dopamine neuronal firing induced by amphetamine. European journal of pharmacology. vol 570. issue 1-3. 2007-11-30. PMID:17586491. |
using extracellular unitary recordings in anaesthetized rats, this study examined the implication of the serotonin 7 (5-ht(7)) receptors in the inhibitory effect of amphetamine on ventral tegmental area and substantia nigra pars compacta dopamine neuronal activity. |
2007-11-30 |
2023-08-12 |
rat |
| Ouissame Mnie-Filali, Lionel Dahan, Luc Zimmer, Nasser Haddjer. Effects of the serotonin 5-HT(7) receptor antagonist SB-269970 on the inhibition of dopamine neuronal firing induced by amphetamine. European journal of pharmacology. vol 570. issue 1-3. 2007-11-30. PMID:17586491. |
the present results suggest that 5-ht(7) receptors modulate the dopamine firing activity in the ventral tegmental area, thus affecting preferentially the mesocorticolimbic pathway. |
2007-11-30 |
2023-08-12 |
rat |
| A R Mesquita, J M Pêgo, T Summavielle, P Maciel, O F X Almeida, N Sous. Neurodevelopment milestone abnormalities in rats exposed to stress in early life. Neuroscience. vol 147. issue 4. 2007-10-31. PMID:17587501. |
there was also a significant increase of the 5-ht turnover in ms2-15 animals in the raphe nuclei, mainly due to increased 5-hydroxyindoleacetic acid (5-hiaa) levels, and an increase of 3,4-dihydroxyphenylacetic acid (dopac) levels in the ventral tegmental area (vta) of stressed females. |
2007-10-31 |
2023-08-12 |
rat |
| Sabiha K Barot, Susan M Ferguson, John F Neumaie. 5-HT(1B) receptors in nucleus accumbens efferents enhance both rewarding and aversive effects of cocaine. The European journal of neuroscience. vol 25. issue 10. 2007-08-17. PMID:17509084. |
viral-mediated gene transfer techniques were used to overexpress 5-ht(1b) receptors in medial nacc shell medium spiny neurons projecting to the ventral tegmental area. |
2007-08-17 |
2023-08-12 |
rat |
| Zachary A Rodd, Victoria E Gryszowka, Jamie E Toalston, Scott M Oster, Dong Ji, Richard L Bell, William J McBrid. The reinforcing actions of a serotonin-3 receptor agonist within the ventral tegmental area: evidence for subregional and genetic differences and involvement of dopamine neurons. The Journal of pharmacology and experimental therapeutics. vol 321. issue 3. 2007-07-30. PMID:17325230. |
studies from our laboratory indicated that local perfusion of the ventral tegmental area (vta) with a serotonin-3 (5-ht(3)) receptor agonist increased dopamine (da) neuronal activity and that the self-infusion of ethanol (etoh) and cocaine into the posterior vta could be inhibited with coadministration of a 5-ht(3) receptor antagonist. |
2007-07-30 |
2023-08-12 |
rat |
| Zachary A Rodd, Victoria E Gryszowka, Jamie E Toalston, Scott M Oster, Dong Ji, Richard L Bell, William J McBrid. The reinforcing actions of a serotonin-3 receptor agonist within the ventral tegmental area: evidence for subregional and genetic differences and involvement of dopamine neurons. The Journal of pharmacology and experimental therapeutics. vol 321. issue 3. 2007-07-30. PMID:17325230. |
the study tested the hypothesis that activating 5-ht(3) receptors within the vta produces reinforcing effects. |
2007-07-30 |
2023-08-12 |
rat |