| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elena Predescu, Tudor Vaidean, Andreea-Marlena Rapciuc, Roxana Sipo. Metabolomic Markers in Attention-Deficit/Hyperactivity Disorder (ADHD) among Children and Adolescents-A Systematic Review. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38673970. |
synthesis revealed intricate links between adhd and altered amino acid metabolism, neurotransmitter dysregulation (especially dopamine and serotonin), oxidative stress, and the kynurenine pathway impacting neurotransmitter homeostasis. |
2024-04-27 |
2024-04-29 |
human |
| Ming Liu, Ping Deng, Guangyu Li, Haoling Liu, Junli Zuo, Wenwen Cui, Huixian Zhang, Xin Chen, Jingjing Yao, Xitian Peng, Lijun Peng, Jiao Liu, Wenting Zheng, Wei Yan, Ning Lua. Neurotoxicity of Combined Exposure to the Heavy Metals (Pb and As) in Zebrafish ( Toxics. vol 12. issue 4. 2024-04-26. PMID:38668505. |
to elucidate the underlying mechanisms, we examined changes in acetylcholinesterase (ache) activity, neurotransmitter (dopamine, 5-hydroxytryptamine) levels, hpi axis-related hormone (cortisol and epinephrine) contents and neurodevelopment-related gene expression in zebrafish brain. |
2024-04-26 |
2024-04-28 |
zebrafish |
| Susanna Molas, Timothy G Freels, Rubing Zhao-Shea, Timothy Lee, Pablo Gimenez-Gomez, Melanie Barbini, Gilles E Martin, Andrew R Tappe. Dopamine control of social novelty preference is constrained by an interpeduncular-tegmentum circuit. Nature communications. vol 15. issue 1. 2024-04-03. PMID:38570514. |
combining calcium and neurotransmitter sensors with fiber photometry and optogenetics in mice, we find that mesolimbic dopamine (da) neurotransmission is strongly and predominantly activated by social novelty controlling bout length of interaction during np, a response significantly reduced by familiarity. |
2024-04-03 |
2024-04-06 |
mouse |
| Maya Molinari, Ori J Lieberman, David Sulzer, Emanuela Santini, Anders Borgkvis. 5-HT1B receptors mediate dopaminergic inhibition of vesicular fusion and GABA release from striatonigral synapses. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559006. |
these d1rs are primarily located on the terminals of striatonigral medium spiny neurons, suggesting their involvement in the regulation of neurotransmitter release from the direct pathway in response to somatodendritic dopamine release. |
2024-04-01 |
2024-04-04 |
Not clear |
| Meghan L Bucher, Amy R Dunn, Joshua M Bradner, Kristen Stout Egerton, James P Burkett, Michelle A Johnson, Gary W Mille. Synaptic vesicle glycoprotein 2C enhances vesicular storage of dopamine and counters dopaminergic toxicity. The European journal of neuroscience. 2024-03-27. PMID:38532289. |
here, we adapted a previously published in vitro assay utilising false fluorescent neurotransmitter 206 (ffn206) to visualise how sv2c regulates vesicular dopamine dynamics and determined that sv2c promotes the uptake and retention of ffn206 within vesicles. |
2024-03-27 |
2024-03-29 |
mouse |
| Érica Novaes Soares, Ana Carla Dos Santos Costa, Gabriel de Jesus Ferrolho, Rodrigo Portes Ureshino, Bruk Getachew, Silvia Lima Costa, Victor Diogenes Amaral da Silva, Yousef Tizab. Nicotinic Acetylcholine Receptors in Glial Cells as Molecular Target for Parkinson's Disease. Cells. vol 13. issue 6. 2024-03-27. PMID:38534318. |
dopamine (da) is the primary neurotransmitter involved in this disease, but cholinergic imbalance has also been implicated. |
2024-03-27 |
2024-03-29 |
Not clear |
| Tony J Prescott, Fernando M Montes González, Kevin Gurney, Mark D Humphries, Peter Redgrav. Simulated Dopamine Modulation of a Neurorobotic Model of the Basal Ganglia. Biomimetics (Basel, Switzerland). vol 9. issue 3. 2024-03-27. PMID:38534824. |
the effective operation of basal ganglia circuitry is also known to rely on appropriate levels of the neurotransmitter dopamine. |
2024-03-27 |
2024-03-29 |
Not clear |
| Nan Song, Zhenhong Liu, Yan Gao, Shanshan Lu, Shenglian Yang, Chao Yua. NAc-DBS corrects depression-like behaviors in CUMS mouse model via disinhibition of DA neurons in the VTA. Molecular psychiatry. 2024-02-16. PMID:38361128. |
moreover, even a single trial nac-dbs led to the elevation of the γ-aminobutyric acid (gaba) neurotransmitter, accompanied by the increase in dopamine (da) neuron activity in the vta. |
2024-02-16 |
2024-02-18 |
mouse |
| Thaina Maquedo Franco, Mariana R Tavares, Leonardo S Novaes, Carolina D Munhoz, Jose Eduardo Peixoto-Santos, Ronaldo C Araujo, Jose Donato, Michael Bader, Frederick Wasinsk. Effects of Bradykinin B2 Receptor Ablation from Tyrosine Hydroxylase Cells on Behavioral and Motor Aspects in Male and Female Mice. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338764. |
dopamine, a key catecholamine neurotransmitter widely distributed in the cns, plays a crucial role in diverse physiological functions including motricity, reward, anxiety, fear, feeding, sleep, and arousal. |
2024-02-10 |
2024-02-12 |
mouse |
| Suzita Mohd Noor, Chee Ern David Wong, Pooi-Fong Wong, Anwar Norazi. Generation of glial cell-derived neurotrophic factor (gdnf) morphants in zebrafish larvae by cerebroventricular microinjection of vivo morpholino. Methods in cell biology. vol 181. 2024-02-01. PMID:38302238. |
dopaminergic neurons in the brain are an important source of dopamine, which is a crucial neurotransmitter for wellbeing, memory, reward, and motor control. |
2024-02-01 |
2024-02-04 |
human |
| Bing Chen, Qian Zhang, Xiaoru Zhong, Xinwei Zhang, Xin Liu, Hongyang Wang, Fan Yang, Jingjing Zhang, Jingnan Huang, Yin-Kwan Wong, Piao Luo, Jigang Wang, Jichao Su. Dopamine modification of glycolytic enzymes impairs glycolysis: possible implications for Parkinson's disease. Cell communication and signaling : CCS. vol 22. issue 1. 2024-01-30. PMID:38287374. |
dopamine (da), the neurotransmitter produced by dopaminergic neurons, and its metabolites can covalently modify proteins, and dysregulation of this process has been implicated in neuronal loss in pd. |
2024-01-30 |
2024-02-01 |
Not clear |
| Yousef Rasmi, Ameneh Shokati, Shima Hatamkhani, Yeganeh Farnamian, Roya Naderi, Ladan Jalal. Assessment of the relationship between the dopaminergic pathway and severe acute respiratory syndrome coronavirus 2 infection, with related neuropathological features, and potential therapeutic approaches in COVID-19 infection. Reviews in medical virology. vol 34. issue 1. 2024-01-29. PMID:38282395. |
dopamine is a known catecholamine neurotransmitter involved in several physiological processes, including motor control, motivation, reward, cognition, and immune function. |
2024-01-29 |
2024-01-31 |
human |
| Jillian L Seiler, Xiaowen Zhuang, Alexandra B Nelson, Talia N Lerne. Dopamine across timescales and cell types: Relevance for phenotypes in Parkinson's disease progression. Experimental neurology. 2024-01-19. PMID:38242300. |
dopamine neurons in the substantia nigra pars compacta (snc) synthesize and release dopamine, a critical neurotransmitter for movement and learning. |
2024-01-19 |
2024-01-22 |
Not clear |
| Atsushi Fujimoto, Catherine Elorette, Satoka H Fujimoto, Lazar Fleysher, Peter H Rudebeck, Brian E Rus. Pharmacological modulation of dopamine D1 and D2 receptors reveals distinct neural networks related to probabilistic learning in non-human primates. bioRxiv : the preprint server for biology. 2024-01-18. PMID:38234858. |
the neurotransmitter dopamine (da) has a multifaceted role in healthy and disordered brains through its action on multiple subtypes of dopaminergic receptors. |
2024-01-18 |
2024-01-20 |
human |
| Smita Sahay, Emily A Devine, Robert E McCullumsmith, Sinead M O'Donova. Adenosine Receptor mRNA Expression in Frontal Cortical Neurons in Schizophrenia. Cells. vol 13. issue 1. 2024-01-11. PMID:38201235. |
schizophrenia is a devastating neuropsychiatric disorder associated with the dysregulation of glutamate and dopamine neurotransmitter systems. |
2024-01-11 |
2024-01-13 |
Not clear |
| Kunwar Jung-Kc, Alba Tristán-Noguero, Altanchimeg Altankhuyag, David Piñol Belenguer, Karina S Prestegård, Irene Fernandez-Carasa, Arianna Colini Baldeshi, Maria Sigatulina Bondarenko, Angeles García-Cazorla, Antonella Consiglio, Aurora Martine. Tetrahydrobiopterin (BH Journal of inherited metabolic disease. 2024-01-10. PMID:38196161. |
tetrahydrobiopterin (bh proteostatic regulation of tyrosine hydroxylase (th), the rate-limiting enzyme in dopamine biosynthesis, is crucial for maintaining proper brain neurotransmitter homeostasis. |
2024-01-10 |
2024-01-13 |
Not clear |
| Ryu Mochizuki, Yasumitsu Ogr. Determination of intracellular dopamine by liquid chromatography-fluorescence detection with post-column derivatization using the König reaction. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 1232. 2023-12-21. PMID:38128164. |
dopamine is an important neurotransmitter, and the disruption of dopaminergic homeostasis causes various neurological diseases such as parkinson's disease. |
2023-12-21 |
2023-12-24 |
Not clear |
| Oliver D Howes, Bernard R Bukala, Katherine Bec. Schizophrenia: from neurochemistry to circuits, symptoms and treatments. Nature reviews. Neurology. 2023-12-19. PMID:38110704. |
this evidence demonstrates regionally specific neurotransmitter alterations, including higher glutamate and dopamine measures in the basal ganglia, and lower glutamate, dopamine and γ-aminobutyric acid (gaba) levels in cortical regions, particularly the frontal cortex, relative to healthy individuals. |
2023-12-19 |
2023-12-21 |
Not clear |
| Laura Kubens, Ann-Kathrin Weishaupt, Vivien Michaelis, Isabelle Rohn, Fabian Mohr, Julia Bornhors. Exposure to the environmentally relevant fungicide Maneb: Studying toxicity in the soil nematode Caenorhabditis elegans. Environment international. vol 183. 2023-12-10. PMID:38071851. |
nevertheless, an alteration in the neurotransmitter homeostasis of dopamine, acetylcholine, and gamma-butyric acid (gaba) was observed as well as morphological changes in the dopaminergic neurons upon maneb exposure, which underlines the assumption of the neurotoxic potential of maneb. |
2023-12-10 |
2023-12-17 |
caenorhabditis_elegans |
| Jin Oh Park, Yongheum Choi, Hyeong Min Ahn, Chang Ki Lee, Honggu Chun, Young Min Park, Kwang Bok Ki. Aggregation of Ag nanoparticle based on surface acoustic wave for surface-enhanced Raman spectroscopy detection of dopamine. Analytica chimica acta. vol 1285. 2023-12-06. PMID:38057052. |
dopamine (da), a vital neurotransmitter, plays a critical role in the human brain and relates to neuropsychiatric disorders such as parkinson's disease and schizophrenia. |
2023-12-06 |
2023-12-10 |
human |