| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sheryl S Smith, Safae Benanni, Quiana Jones, Lindsay Kenney, Matthew Evrar. Manipulation of α4βδ GABA Brain research. 2024-04-10. PMID:38599510. |
manipulation of α4βδ gaba temporal order memory is impaired in autism spectrum disorder (asd) and schizophrenia (scz). |
2024-04-10 |
2024-04-13 |
mouse |
| Laurie-Anne Sapey-Triomphe, Nicolaas A J Puts, Thiago L Costa, Johan Wageman. GABA and Glx predict EEG responses of visual sensitivity in autism. Autism research : official journal of the International Society for Autism Research. 2024-04-05. PMID:38576253. |
gaba and glx predict eeg responses of visual sensitivity in autism. |
2024-04-05 |
2024-04-07 |
Not clear |
| Jason D Braga, Masubon Thongngam, Thanutchaporn Kumrungse. Gamma-aminobutyric acid as a potential postbiotic mediator in the gut-brain axis. NPJ science of food. vol 8. issue 1. 2024-04-02. PMID:38565567. |
this review article will cover up-to-date information about gaba-producing microorganisms isolated from human gut and food sources, explanation why those microorganisms produce gaba, food factors inducing gut-gaba production, evidence suggesting gaba as a mediator linking between gut microbiota and mental health, including anxiety, depression, stress, epilepsy, autism spectrum disorder, and attention deficit hyperactivity disorder, and novel information regarding homocarnosine-a predominant brain peptide that is a putative downstream mediator of gaba in regulating brain functions. |
2024-04-02 |
2024-04-05 |
human |
| Qiyun Huang, Claire L Ellis, Shaun M Leo, Hester Velthuis, Andreia C Pereira, Mihail Dimitrov, Francesca M Ponteduro, Nichol M L Wong, Eileen Daly, Declan G M Murphy, Omar A Mahroo, Gráinne M McAlona. Retinal GABAergic alterations in adults with autism spectrum disorder. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-03-11. PMID:38467434. |
alterations in γ-aminobutyric acid (gaba) have been implicated in sensory differences in individuals with autism spectrum disorder (asd). |
2024-03-11 |
2024-03-14 |
human |
| Kavitha Ukkirapandian, Kayalvizhi Elumalai, Karthika Priyadharshini Udaykumar, Sundaravadivel Vp, Muthulakshmi Rangasm. Behavioral and Biochemical Assays for Autism Models of Wistar Rats. Cureus. vol 16. issue 1. 2024-02-13. PMID:38344592. |
rats with autism had a significant decrease in gaba and bdnf levels. |
2024-02-13 |
2024-02-15 |
rat |
| Amjad Mhanna, Nafiza Martini, Ghefar Hmaydoosh, George Hamwi, Mulham Jarjanazi, Ghaith Zaifah, Reem Kazzazo, Aya Haji Mohamad, Zuheir Alshehab. The correlation between gut microbiota and both neurotransmitters and mental disorders: A narrative review. Medicine. vol 103. issue 5. 2024-02-02. PMID:38306525. |
this review aims to summarize the modulation role of the gut microbiota in 4 prominent neurotransmitters (tryptophan and serotonergic system, dopamine, gamma-aminobutyric acid, and glutamate), as well as its association with 4 psychiatric disorders (schizophrenia, depression, anxiety disorders, and autism spectrum disorder). |
2024-02-02 |
2024-02-05 |
Not clear |
| Sania Grover, Raj Kumar Narang, Shamsher Sing. GABA-Transaminase: A Key Player and Potential Therapeutic Target for Neurological Disorders. Central nervous system agents in medicinal chemistry. 2024-01-20. PMID:38243961. |
in huntington's disease, epilepsy, and multiple sclerosis, the surfeited performance of gaba-t results in diminished levels of gaba, whereas in autism, the subsidence of gaba-t activity causes the elevation in gaba contents, which is responsible for behavioral changes in these disorders. |
2024-01-20 |
2024-01-23 |
Not clear |
| Duanghathai Pasanta, David J White, Jason L He, Talitha C Ford, Nicolaas A Put. GABA and glutamate response to social processing: a functional MRS feasibility study. NMR in biomedicine. 2023-12-28. PMID:38154459. |
autism) is associated with differences in excitation and inhibition, through changes in the levels of glutamate and gamma-aminobutyric acid (gaba). |
2023-12-28 |
2023-12-31 |
Not clear |
| Nina-Francesca Parrella, Aron T Hill, Lillian M Dipnall, Yuk Jing Loke, Peter G Enticott, Talitha C For. Inhibitory dysfunction and social processing difficulties in autism: A comprehensive narrative review. Journal of psychiatric research. vol 169. 2023-11-28. PMID:38016393. |
the primary inhibitory neurotransmitter γ-aminobutyric acid (gaba) has a prominent role in regulating neural development and function, with disruption to gabaergic signalling linked to behavioural phenotypes associated with neurodevelopmental disorders, particularly autism. |
2023-11-28 |
2023-12-07 |
Not clear |
| Nina-Francesca Parrella, Aron T Hill, Lillian M Dipnall, Yuk Jing Loke, Peter G Enticott, Talitha C For. Inhibitory dysfunction and social processing difficulties in autism: A comprehensive narrative review. Journal of psychiatric research. vol 169. 2023-11-28. PMID:38016393. |
many of the social processing difficulties experienced in autism have been linked to higher levels of the excitatory neurotransmitter glutamate and/or lower levels of inhibitory gaba. |
2023-11-28 |
2023-12-07 |
Not clear |
| Nina-Francesca Parrella, Aron T Hill, Lillian M Dipnall, Yuk Jing Loke, Peter G Enticott, Talitha C For. Inhibitory dysfunction and social processing difficulties in autism: A comprehensive narrative review. Journal of psychiatric research. vol 169. 2023-11-28. PMID:38016393. |
while current therapeutic options for social difficulties in autism are largely limited to behavioural interventions, this review highlights the psychopharmacological studies that explore the utility of gaba modulation in alleviating such difficulties. |
2023-11-28 |
2023-12-07 |
Not clear |
| Allegra J Johnson, Eric Shankland, Todd Richards, Neva Corrigan, Dennis Shusterman, Richard Edden, Annette Estes, Tanya St John, Stephen Dager, Natalia M Kleinhan. Relationships between GABA, glutamate, and GABA/glutamate and social and olfactory processing in children with autism spectrum disorder. Psychiatry research. Neuroimaging. vol 336. 2023-11-13. PMID:37956467. |
relationships between gaba, glutamate, and gaba/glutamate and social and olfactory processing in children with autism spectrum disorder. |
2023-11-13 |
2023-11-20 |
human |
| Allegra J Johnson, Eric Shankland, Todd Richards, Neva Corrigan, Dennis Shusterman, Richard Edden, Annette Estes, Tanya St John, Stephen Dager, Natalia M Kleinhan. Relationships between GABA, glutamate, and GABA/glutamate and social and olfactory processing in children with autism spectrum disorder. Psychiatry research. Neuroimaging. vol 336. 2023-11-13. PMID:37956467. |
theories of altered inhibitory/excitatory signaling in autism spectrum disorder (asd) suggest that gamma amino butyric acid (gaba) and glutamate (glu) abnormalities may underlie social and sensory challenges in asd. |
2023-11-13 |
2023-11-20 |
human |
| Xiaona Wang, Zhengqin Zhao, Jisheng Guo, Daoqi Mei, Yongtao Duan, Yaodong Zhang, Lingshan Go. GABA Brain research bulletin. 2023-09-07. PMID:37678443. |
gaba autism spectrum disorder (asd) is a set of heterogeneous neurodevelopmental disorders, characterized by social interaction deficit, stereotyped or repetitive behaviors. |
2023-09-07 |
2023-10-07 |
Not clear |
| Itay Tokatly Latzer, Ellen Hanson, Mariarita Bertoldi, Àngeles García-Cazorla, Melissa Tsuboyama, Paul MacMullin, Alexander Rotenberg, Jean-Baptiste Roullet, Phillip L Pear. Autism spectrum disorder and GABA levels in children with succinic semialdehyde dehydrogenase deficiency. Developmental medicine and child neurology. 2023-05-29. PMID:37246331. |
autism spectrum disorder and gaba levels in children with succinic semialdehyde dehydrogenase deficiency. |
2023-05-29 |
2023-08-14 |
Not clear |
| Itay Tokatly Latzer, Ellen Hanson, Mariarita Bertoldi, Àngeles García-Cazorla, Melissa Tsuboyama, Paul MacMullin, Alexander Rotenberg, Jean-Baptiste Roullet, Phillip L Pear. Autism spectrum disorder and GABA levels in children with succinic semialdehyde dehydrogenase deficiency. Developmental medicine and child neurology. 2023-05-29. PMID:37246331. |
to elucidate the etiological aspects of autism spectrum disorder (asd) in succinic semialdehyde dehydrogenase deficiency (ssadhd), related to dysregulation of γ-aminobutyric acid (gaba) and the imbalance of excitatory and inhibitory neurotransmission. |
2023-05-29 |
2023-08-14 |
Not clear |
| Tiffany Hong, Erin McBride, Brett D Dufour, Carmen Falcone, Mai Doan, Stephen G Noctor, Verónica Martínez-Cerdeñ. Synaptic boutons are smaller in chandelier cell cartridges in autism. PloS one. vol 18. issue 4. 2023-04-25. PMID:37097993. |
previous studies indicate that the number of ch cells is decreased in autism, and that gaba receptors are decreased in the ch cell synaptic target in the prefrontal cortex. |
2023-04-25 |
2023-08-14 |
human |
| Ender M Coskunpinar, Seymanur Tur, Nagihan Cevher Binici, Cisel Yazan Songü. Association of GABRG3, GABRB3, HTR2A Gene Variants with Autism Spectrum Disorder. Gene. 2023-04-05. PMID:37019319. |
in this study, we focused on gamma amino butyric acid (gaba) and serotonin, which are thought to contribute to the etiology of autism; it is aimed to elucidate the mechanism of the disease by investigating variant changes in the gaba receptor subunit genes gabrb3, gabrg3 and the htr2a gene, which encodes one of the serotonin receptors. |
2023-04-05 |
2023-08-14 |
human |
| Iveta Jahodova, Martina Baliova, Frantisek Jursk. PDZ interaction of the GABA transporter GAT1 with the syntenin-1 in Neuro-2a cells. Neurochemistry international. 2023-03-26. PMID:36966820. |
the gaba transporter gat1 regulates brain inhibitory neurotransmission and it is considered a potential therapeutic target for the treatment of wide spectrum of neurological diseases including epilepsy, stroke and autism. |
2023-03-26 |
2023-08-14 |
Not clear |
| Hiroshi Hanamoto, Yohsuke Hirose, Midori Toyama, Chizuko Yokoe, Aiko Oyamaguchi, Hitoshi Niw. Effect of midazolam in autism spectrum disorder: A retrospective observational analysis. Acta anaesthesiologica Scandinavica. 2023-02-08. PMID:36754992. |
while midazolam is commonly used as premedication for uncooperative patients, its effects are difficult to predict in patients with autism spectrum disorder for whom abnormalities in gamma-aminobutyric acid have been reported. |
2023-02-08 |
2023-08-14 |
Not clear |