All Relations between Alzheimer Disease and Aphasia, Primary Progressive

Publication Sentence Publish Date Extraction Date Species
Arnaud Marcoux, Ninon Burgos, Anne Bertrand, Marc Teichmann, Alexandre Routier, Junhao Wen, Jorge Samper-González, Simona Bottani, Stanley Durrleman, Marie-Odile Habert, Olivier Collio. An Automated Pipeline for the Analysis of PET Data on the Cortical Surface. Frontiers in neuroinformatics. vol 12. 2020-10-01. PMID:30618699. we evaluated the performance of the proposed workflow by performing group comparisons and showed that the approach was able to identify the areas of hypometabolism characteristic of different dementia syndromes: alzheimer's disease (ad) and both the semantic and logopenic variants of primary progressive aphasia. 2020-10-01 2023-08-13 human
Chris J D Hardy, Rebecca L Bond, Kankamol Jaisin, Charles R Marshall, Lucy L Russell, Katrina Dick, Sebastian J Crutch, Jonathan D Rohrer, Jason D Warre. Sensitivity of Speech Output to Delayed Auditory Feedback in Primary Progressive Aphasias. Frontiers in neurology. vol 9. 2020-09-30. PMID:30420829. here we studied two forms of speech output (reading aloud and propositional speech) under natural listening conditions (no feedback delay) and under daf at 200 ms, in a cohort of 19 patients representing all major primary progressive aphasia syndromes vs. healthy older individuals and patients with other canonical dementia syndromes (typical alzheimer's disease and behavioral variant frontotemporal dementia). 2020-09-30 2023-08-13 Not clear
Maxime Montembeault, Marianne Chapleau, Julien Jarret, Mariem Boukadi, Robert Laforce, Maximiliano A Wilson, Isabelle Rouleau, Simona M Brambat. Differential language network functional connectivity alterations in Alzheimer's disease and the semantic variant of primary progressive aphasia. Cortex; a journal devoted to the study of the nervous system and behavior. vol 117. 2020-09-30. PMID:31034993. differential language network functional connectivity alterations in alzheimer's disease and the semantic variant of primary progressive aphasia. 2020-09-30 2023-08-13 Not clear
Maxime Montembeault, Marianne Chapleau, Julien Jarret, Mariem Boukadi, Robert Laforce, Maximiliano A Wilson, Isabelle Rouleau, Simona M Brambat. Differential language network functional connectivity alterations in Alzheimer's disease and the semantic variant of primary progressive aphasia. Cortex; a journal devoted to the study of the nervous system and behavior. vol 117. 2020-09-30. PMID:31034993. patients with alzheimer's disease (ad) and semantic variant primary progressive aphasia (svppa) can present with similar language impairments, mainly in naming. 2020-09-30 2023-08-13 Not clear
Veronica Boschi, Eleonora Catricalà, Monica Consonni, Cristiano Chesi, Andrea Moro, Stefano F Capp. Connected Speech in Neurodegenerative Language Disorders: A Review. Frontiers in psychology. vol 8. 2020-09-29. PMID:28321196. here we present an exhaustive review of the studies focusing on the linguistic variables derived from the analysis of connected speech samples, with the aim of characterizing the language disorders of the most prevalent neurodegenerative diseases, including primary progressive aphasia, alzheimer's disease, movement disorders, and amyotrophic lateral sclerosis. 2020-09-29 2023-08-13 Not clear
Sachiko Nakayama, Shotaro Shimonaka, Montasir Elahi, Kenya Nishioka, Yutaka Oji, Shin-Ei Matsumoto, Yuanzhe Li, Hiroyo Yoshino, Kaoru Mogushi, Taku Hatano, Takeshi Sato, Teikichi Ikura, Nobutoshi Ito, Yumiko Motoi, Nobutaka Hattor. Tau aggregation and seeding analyses of two novel MAPT variants found in patients with motor neuron disease and progressive parkinsonism. Neurobiology of aging. vol 84. 2020-08-04. PMID:31027853. through genetic screening of 165 cases possibly associated with tauopathies, including 88 alzheimer's disease, 26 behavioral variant ftd, eight primary progressive aphasia, nine ftd with motor neuron disease, 21 progressive supranuclear palsy, and 13 corticobasal syndrome, we identified two novel mapt variants: a heterozygous missense variant, p.p160s, in a patient with ftd with motor neuron disease and a heterozygous insertional variant, p.k298_h299insq, in three patients with familial progressive supranuclear palsy. 2020-08-04 2023-08-13 Not clear
P Novak, N Zilka, M Zilkova, B Kovacech, R Skrabana, M Ondrus, L Fialova, E Kontsekova, M Otto, M Nova. AADvac1, an Active Immunotherapy for Alzheimer's Disease and Non Alzheimer Tauopathies: An Overview of Preclinical and Clinical Development. The journal of prevention of Alzheimer's disease. vol 6. issue 1. 2020-08-03. PMID:30569088. aadvac1 is currently being investigated in a phase 2 study in alzheimer's disease, and a phase 1 study in non-fluent primary progressive aphasia, a neurodegenerative disorder with a high tau pathology component. 2020-08-03 2023-08-13 mouse
Ashleigh Beales, Kristyn Bates, Jade Cartwright, Anne Whitwort. Lost for words: Perspectives and experiences of people with primary progressive aphasia and Alzheimer's disease and their families of participation in a lexical retrieval intervention. International journal of speech-language pathology. vol 21. issue 5. 2020-04-13. PMID:31208244. lost for words: perspectives and experiences of people with primary progressive aphasia and alzheimer's disease and their families of participation in a lexical retrieval intervention. 2020-04-13 2023-08-13 Not clear
Martha S Foiani, Claudia Cicognola, Natalia Ermann, Ione O C Woollacott, Carolin Heller, Amanda J Heslegrave, Ashvini Keshavan, Ross W Paterson, Keqiang Ye, Johannes Kornhuber, Nick C Fox, Jonathan M Schott, Jason D Warren, Piotr Lewczuk, Henrik Zetterberg, Kaj Blennow, Kina Höglund, Jonathan D Rohre. Searching for novel cerebrospinal fluid biomarkers of tau pathology in frontotemporal dementia: an elusive quest. Journal of neurology, neurosurgery, and psychiatry. vol 90. issue 7. 2020-03-17. PMID:30981993. frontotemporal dementia (ftd) is a pathologically heterogeneous neurodegenerative disorder associated usually with tau or tdp-43 pathology, although some phenotypes such as logopenic variant primary progressive aphasia are more commonly associated with alzheimer's disease pathology. 2020-03-17 2023-08-13 Not clear
Matías Niikado, Patricio Chrem-Méndez, Tatiana Itzcovich, Micaela Barbieri-Kennedy, Ismael Calandri, Horacio Martinetto, Mercedes Serra, Jorge Calvar, Jorge Campos, María Julieta Russo, Lucía Pertierra, Ricardo Allegri, Gustavo Sevlever, Ezequiel I Surac. Evaluation of Cerebrospinal Fluid Neurofilament Light Chain as a Routine Biomarker in a Memory Clinic. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 74. issue 4. 2019-12-26. PMID:30107413. clinical conditions included mild cognitive impairment (mci, n = 12), dementia of alzheimer's type (dat, n = 14), behavioral variant frontotemporal dementia (bvftd, n = 13), and primary progressive aphasia (logopenic [n = 6], semantic [n = 2], and nonfluent [n = 4]). 2019-12-26 2023-08-13 Not clear
Gianina Toller, Winson F Z Yang, Jesse A Brown, Kamalini G Ranasinghe, Suzanne M Shdo, Joel H Kramer, William W Seeley, Bruce L Miller, Katherine P Ranki. Divergent patterns of loss of interpersonal warmth in frontotemporal dementia syndromes are predicted by altered intrinsic network connectivity. NeuroImage. Clinical. vol 22. 2019-12-26. PMID:30836325. we used reliable change indexes with premorbid and current informant-based evaluations to characterize patterns of change on the warmth subscale of the interpersonal adjective scale (ias) questionnaire in 132 patients (21 bvftd, 19 svppa, 22 nonfluent variant primary progressive aphasia [nfvppa], 37 alzheimer's disease [ad]) and 33 healthy older adults. 2019-12-26 2023-08-13 Not clear
M-Marsel Mesulam, Nava Lalehzari, Farzan Rahmani, Daniel Ohm, Ryan Shahidehpour, Garam Kim, Tamar Gefen, Sandra Weintraub, Eileen Bigio, Changiz Geul. Cortical cholinergic denervation in primary progressive aphasia with Alzheimer pathology. Neurology. vol 92. issue 14. 2019-12-10. PMID:30842294. cortical cholinergic denervation in primary progressive aphasia with alzheimer pathology. 2019-12-10 2023-08-13 Not clear
Gianina Toller, Jesse Brown, Marc Sollberger, Suzanne M Shdo, Laura Bouvet, Paul Sukhanov, William W Seeley, Bruce L Miller, Katherine P Ranki. Individual differences in socioemotional sensitivity are an index of salience network function. Cortex; a journal devoted to the study of the nervous system and behavior. vol 103. 2019-10-11. PMID:29656245. we measured sn functional connectivity and socioemotional sensitivity in 65 healthy older adults and 103 patients in the earliest stage [clinical dementia rating (cdr) scale score ≤1] of five neurodegenerative diseases [14 bvftd, 29 alzheimer's disease (ad), 20 progressive supranuclear palsy (psp), 21 semantic variant primary progressive aphasia (svppa), and 19 non-fluent variant primary progressive aphasia (nfvppa)]. 2019-10-11 2023-08-13 human
Sara J Makaretz, Megan Quimby, Jessica Collins, Nikos Makris, Scott McGinnis, Aaron Schultz, Neil Vasdev, Keith A Johnson, Bradford C Dickerso. Flortaucipir tau PET imaging in semantic variant primary progressive aphasia. Journal of neurology, neurosurgery, and psychiatry. vol 89. issue 10. 2019-10-02. PMID:28986472. the semantic variant of primary progressive aphasia (svppa) is typically associated with frontotemporal lobar degeneration (ftld) with longtar dna-binding protein (tdp)-43-positive neuropil threads and dystrophic neurites (type c), and is only rarely due to a primary tauopathy or alzheimer's disease. 2019-10-02 2023-08-13 Not clear
Géraldine Bera, Raffaella Migliaccio, Thibaut Michelin, Foudil Lamari, Sophie Ferrieux, Marie Nogues, Hugo Bertin, Marie Odile Habert, Bruno Dubois, Marc Teichmann, Aurélie Ka. Parietal Involvement in the Semantic Variant of Primary Progressive Aphasia with Alzheimer's Disease Cerebrospinal Fluid Profile. Journal of Alzheimer's disease : JAD. vol 66. issue 1. 2019-09-19. PMID:30282352. parietal involvement in the semantic variant of primary progressive aphasia with alzheimer's disease cerebrospinal fluid profile. 2019-09-19 2023-08-13 Not clear
Chris J D Hardy, Charles R Marshall, Rebecca L Bond, Lucy L Russell, Katrina Dick, Cono Ariti, David L Thomas, Sonya J Ross, Jennifer L Agustus, Sebastian J Crutch, Jonathan D Rohrer, Doris-Eva Bamiou, Jason D Warre. Retained capacity for perceptual learning of degraded speech in primary progressive aphasia and Alzheimer's disease. Alzheimer's research & therapy. vol 10. issue 1. 2019-08-06. PMID:30045755. retained capacity for perceptual learning of degraded speech in primary progressive aphasia and alzheimer's disease. 2019-08-06 2023-08-13 Not clear
Aline Mendes, Anne Bertrand, Foudil Lamari, Olivier Colliot, Alexandre Routier, Olivier Godefroy, Frédérique Etcharry-Bouyx, Olivier Moreaud, Florence Pasquier, Philippe Couratier, Karim Bennys, Martine Vercelletto, Olivier Martinaud, Bernard Laurent, Jérémie Pariente, Michèle Puel, Stéphane Epelbaum, Serge Belliard, Takoua Kaaouana, Ludovic Fillon, Marie Chupin, Bruno Dubois, Marc Teichman. Cerebral microbleeds and CSF Alzheimer biomarkers in primary progressive aphasias. Neurology. vol 90. issue 12. 2019-07-30. PMID:29444966. to reveal the prevalence and localization of cerebral microbleeds (cmbs) in the 3 main variants of primary progressive aphasia (ppa) (logopenic, semantic, and nonfluent/agrammatic), to identify the relationship with underlying alzheimer pathology, and to explore whether cmbs contribute to language breakdown. 2019-07-30 2023-08-13 Not clear
Mario F Mendez, Negar Moheb, Randy E Desarzant, Edmond H Ten. The Progressive Acalculia Presentation of Parietal Variant Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 63. issue 3. 2019-06-10. PMID:29710718. many patients with early-onset alzheimer's disease (eoad; age of onset <65 years) have non-amnestic presentations involving language (logopenic primary progressive aphasia, lvppa), visuospatial abilities (posterior cortical atrophy, pca), and even asymmetric symptoms consistent with corticobasal syndrome (cbs). 2019-06-10 2023-08-13 Not clear
Ashleigh Beales, Anne Whitworth, Jade Cartwright, Peter K Panegyres, Robert T Kan. Determining stability in connected speech in primary progressive aphasia and Alzheimer's disease. International journal of speech-language pathology. vol 20. issue 3. 2019-03-13. PMID:29516757. determining stability in connected speech in primary progressive aphasia and alzheimer's disease. 2019-03-13 2023-08-13 Not clear
Ilya M Nasrallah, Yin Jie Chen, Meng-Kang Hsieh, Jeffrey S Phillips, Kylie Ternes, Grace E Stockbower, Yvette Sheline, Corey T McMillan, Murray Grossman, David A Wol. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 59. issue 2. 2019-03-12. PMID:28747523. nonamnestic alzheimer disease (ad) variants, including posterior cortical atrophy and the logopenic variant of primary progressive aphasia, differ from amnestic ad in distributions of tau aggregates and neurodegeneration. 2019-03-12 2023-08-13 Not clear