| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xin-Kang Tong, Jessika Royea, Edith Hame. Simvastatin rescues memory and granule cell maturation through the Wnt/β-catenin signaling pathway in a mouse model of Alzheimer's disease. Cell death & disease. vol 13. issue 4. 2022-04-10. PMID:35397630. |
we previously showed that simvastatin (sv) restored memory in a mouse model of alzheimer disease (ad) concomitantly with normalization in protein levels of memory-related immediate early genes in hippocampal ca1 neurons. |
2022-04-10 |
2023-08-13 |
mouse |
| Anam Islam, Takashi Saito, Takaomi Saido, Afia B Al. Presubiculum principal cells are preserved from degeneration in knock-in APP/TAU mouse models of Alzheimer's disease. Seminars in cell & developmental biology. 2022-03-16. PMID:35292192. |
the presubiculum (prs) is an integral component of the perforant pathway that has recently been recognised as a relatively unscathed region in clinical alzheimer's disease (ad), despite neighbouring components of the perforant pathway, ca1 and the entorhinal cortex, responsible for formation of episodic memory and storage, showing severe hallmarks of ad including, amyloid-beta (aβ) plaques, tau tangles and marked gliosis. |
2022-03-16 |
2023-08-13 |
mouse |
| Chengju Tian, Isabel Reyes, Arjun V Masurka. Differential alterations of entorhinal versus CA3 impact on ventral CA1 pyramidal neurons in 5xFAD mice. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35109258. |
most hippocampal physiologic studies in alzheimer disease (ad) have focused on memory circuit dysfunction in dorsal ca1. |
2022-02-03 |
2023-08-13 |
mouse |
| Erratum: Takamura et al., "Modality-Specific Impairment of Hippocampal CA1 Neurons of Alzheimer's Disease Model Mice". The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-01-28. PMID:35086907. |
erratum: takamura et al., "modality-specific impairment of hippocampal ca1 neurons of alzheimer's disease model mice". |
2022-01-28 |
2023-08-13 |
mouse |
| Ryszard Pluta, Wanda Furmaga-Jabłońska, Sławomir Januszewski, Stanisław J Czuczwa. Post-Ischemic Brain Neurodegeneration in the Form of Alzheimer's Disease Proteinopathy: Possible Therapeutic Role of Curcumin. Nutrients. vol 14. issue 2. 2022-01-21. PMID:35057429. |
the observed death of pyramidal neurons in the ca1 region of the hippocampus and its atrophy are considered to be typical changes for post-ischemic brain neurodegeneration and for alzheimer's disease. |
2022-01-21 |
2023-08-13 |
human |
| Melania Gonzalez-Rodriguez, Sandra Villar-Conde, Veronica Astillero-Lopez, Patricia Villanueva-Anguita, Isabel Ubeda-Banon, Alicia Flores-Cuadrado, Alino Martinez-Marcos, Daniel Saiz-Sanche. Neurodegeneration and Astrogliosis in the Human CA1 Hippocampal Subfield Are Related to hsp90ab1 and bag3 in Alzheimer's Disease. International journal of molecular sciences. vol 23. issue 1. 2022-01-11. PMID:35008592. |
neurodegeneration and astrogliosis in the human ca1 hippocampal subfield are related to hsp90ab1 and bag3 in alzheimer's disease. |
2022-01-11 |
2023-08-13 |
human |
| Le Xu, Yiying Zhou, Linbo Hu, Hongde Jiang, Yibei Dong, Haowei Shen, Zhongze Lou, Siyu Yang, Yunxin Ji, Liemin Ruan, Xiaoqin Zhan. Deficits in N-Methyl-D-Aspartate Receptor Function and Synaptic Plasticity in Hippocampal CA1 in APP/PS1 Mouse Model of Alzheimer's Disease. Frontiers in aging neuroscience. vol 13. 2021-12-17. PMID:34916926. |
deficits in n-methyl-d-aspartate receptor function and synaptic plasticity in hippocampal ca1 in app/ps1 mouse model of alzheimer's disease. |
2021-12-17 |
2023-08-13 |
mouse |
| Étienne Gervais, Parisa Iloun, Ekaterina Martianova, Ana Claudia Gonçalves Bessa, Serge Rivest, Lisa Topolni. Structural analysis of the microglia-interneuron interactions in the CA1 hippocampal area of the APP/PS1 mouse model of Alzheimer's disease. The Journal of comparative neurology. 2021-12-17. PMID:34919273. |
structural analysis of the microglia-interneuron interactions in the ca1 hippocampal area of the app/ps1 mouse model of alzheimer's disease. |
2021-12-17 |
2023-08-13 |
mouse |
| Étienne Gervais, Parisa Iloun, Ekaterina Martianova, Ana Claudia Gonçalves Bessa, Serge Rivest, Lisa Topolni. Structural analysis of the microglia-interneuron interactions in the CA1 hippocampal area of the APP/PS1 mouse model of Alzheimer's disease. The Journal of comparative neurology. 2021-12-17. PMID:34919273. |
here, we compared the interactions between microglia and parvalbumin (pv+) and somatostatin (som+) expressing interneurons in the ca1 hippocampal area of app/ps1 transgenic mice that mimic certain aspects of the alzheimer's disease (ad). |
2021-12-17 |
2023-08-13 |
mouse |
| Risa Takamura, Kotaro Mizuta, Yukiko Sekine, Tanvir Islam, Takashi Saito, Masaaki Sato, Masamichi Ohkura, Junichi Nakai, Toshio Ohshima, Takaomi C Saido, Yasunori Hayash. Modality-Specific Impairment of Hippocampal CA1 Neurons of Alzheimer's Disease Model Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 24. 2021-11-22. PMID:33980545. |
modality-specific impairment of hippocampal ca1 neurons of alzheimer's disease model mice. |
2021-11-22 |
2023-08-13 |
mouse |
| He-Ao Zhang, Chun-Xu Yuan, Ke-Fu Liu, Qi-Fan Yang, Juan Zhao, Hui Li, Qing-Hu Yang, Da Song, Zhen-Zhen Quan, Hong Qin. Neural stem cell transplantation alleviates functional cognitive deficits in a mouse model of tauopathy. Neural regeneration research. vol 17. issue 1. 2021-10-22. PMID:34100451. |
in this study, nscs were transplanted into the hippocampal ca1 region of the rtg (tau p301l) 4510 mouse model, a tauopathy model that is thought to reflect the tau pathology associated with alzheimer's disease. |
2021-10-22 |
2023-08-13 |
mouse |
| Jian-Zhong Li, Xing-Hua Hao, Hai-Ping Wu, Ming Li, Xue-Min Liu, Zhi-Bing W. An enriched environment delays the progression from mild cognitive impairment to Alzheimer's disease in senescence-accelerated mouse prone 8 mice. Experimental and therapeutic medicine. vol 22. issue 5. 2021-10-12. PMID:34630674. |
these results demonstrate that ee exposure effectively decreases neuronal loss and regulates neuronal synaptic plasticity by reducing the expression of app and the deposition of aβ in the hippocampal ca1 region, thereby mitigating cognitive decline in samp8 mice during the mci phase and delaying the progression from mci to alzheimer's disease. |
2021-10-12 |
2023-08-13 |
mouse |
| Rasha H Mehder, Brian M Bennett, R David Andre. Age-Related Neuronal Deterioration Specifically Within the Dorsal CA1 Region of the Hippocampus in a Mouse Model of Late Onset Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 79. issue 4. 2021-09-15. PMID:33459722. |
age-related neuronal deterioration specifically within the dorsal ca1 region of the hippocampus in a mouse model of late onset alzheimer's disease. |
2021-09-15 |
2023-08-13 |
mouse |
| Simon Gelman, Jonathan Palma, Afshin Ghavam. Axonal Conduction Velocity in CA1 Area of Hippocampus is Reduced in Mouse Models of Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 77. issue 4. 2021-09-10. PMID:32925062. |
axonal conduction velocity in ca1 area of hippocampus is reduced in mouse models of alzheimer's disease. |
2021-09-10 |
2023-08-13 |
mouse |
| Javan Lee Tze Han, Karen Ka Lam Pang, Sheila Rui Xia Ang, Mahima Sharma, Sreedharan Sajikuma. Inhibition of lysine methyltransferase G9a/GLP reinstates long-term synaptic plasticity and synaptic tagging/capture by facilitating protein synthesis in the hippocampal CA1 area of APP/PS1 mouse model of Alzheimer's disease. Translational neurodegeneration. vol 10. issue 1. 2021-08-04. PMID:34187583. |
inhibition of lysine methyltransferase g9a/glp reinstates long-term synaptic plasticity and synaptic tagging/capture by facilitating protein synthesis in the hippocampal ca1 area of app/ps1 mouse model of alzheimer's disease. |
2021-08-04 |
2023-08-13 |
mouse |
| Made Bagus Auriva Mataram, Puspa Hening, Fitria N Harjanti, Srikanth Karnati, Widya Wasityastuti, Dwi Aris Agung Nugrahaningsih, Dwi Liliek Kusindarta, Hevi Wihadmadyatam. The neuroprotective effect of ethanolic extract Ocimum sanctum Linn. in the regulation of neuronal density in hippocampus areas as a central autobiography memory on the rat model of Alzheimer's disease. Journal of chemical neuroanatomy. vol 111. 2021-07-15. PMID:33188864. |
ethanolic extract (ose) on the neurons of the ca1, ca3, and dg hippocampal areas with the use of in vivo and in vitro models of alzheimer's diseases (ad). |
2021-07-15 |
2023-08-13 |
rat |
| Anqi Shi, Alexandra L Petrache, Jiachen Shi, Afia B Al. Preserved Calretinin Interneurons in an App Model of Alzheimer's Disease Disrupt Hippocampal Inhibition via Upregulated P2Y1 Purinoreceptors. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 3. 2021-06-09. PMID:31407772. |
to understand the pathogenesis of specific neuronal circuit dysfunction in alzheimer's disease (ad), we investigated the fate of three subclasses of "modulatory interneurons" in hippocampal ca1 using the appnl-f/nl-f knock-in mouse model of ad. |
2021-06-09 |
2023-08-13 |
mouse |
| Daruoosh Zare, Mohammad Amin Rajizadeh, Marzieh Maneshian, Hossein Jonaidi, Vahid Sheibani, Majid Asadi-Shekaari, Manouchehr Yousefi, Khadijeh Esmaeilpou. Inhibition of protease-activated receptor 1 (PAR1) ameliorates cognitive performance and synaptic plasticity impairments in animal model of Alzheimer's diseases. Psychopharmacology. vol 238. issue 6. 2021-06-01. PMID:33624157. |
the aim of the present study was to evaluate the effect of par1 inhibition by using sch (as an inhibitor of par1) on spatial learning, memory, and synaptic plasticity in the ca1 region of the hippocampus in rat model of alzheimer's disease. |
2021-06-01 |
2023-08-13 |
rat |
| Hyeon Jeong Seo, Jung Eun Park, Seong-Min Choi, Taekyoung Kim, Soo Hyun Cho, Kyung-Hwa Lee, Woo Keun Song, Juhyun Song, Han-Seong Jeong, Dong Hyun Kim, Byeong C Ki. Inhibitory Neural Network's Impairments at Hippocampal CA1 LTP in an Aged Transgenic Mouse Model of Alzheimer's Disease. International journal of molecular sciences. vol 22. issue 2. 2021-04-02. PMID:33445678. |
inhibitory neural network's impairments at hippocampal ca1 ltp in an aged transgenic mouse model of alzheimer's disease. |
2021-04-02 |
2023-08-13 |
mouse |
| Ting Ye, Xinquan Li, Peng Zhou, Shu Ye, Huawu Gao, Rupeng Hua, Junlong Ma, Yan Wang, Biao Ca. Chrysophanol improves memory ability of d-galactose and Aβ 3 Biotech. vol 10. issue 3. 2021-03-02. PMID:32117672. |
an alzheimer's disease rat model was established using an intraperitoneal injection of d-galactose combined with an intracerebral injection of amyloid-β peptide (25-35), and the effect of chr on the learning and memory ability, the hippocampal neurons change, the ultrastructure of the hippocampal ca1 region, the protein levels of cam, camkk, camkiv, p-camkiv and p-tau in the hippocampus of rats were studied. |
2021-03-02 |
2023-08-13 |
rat |