| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Srikanth R Damera, Josepheen De Asis-Cruz, Kevin M Cook, Kushal Kapse, Emma Spoehr, Jon Murnick, Sudeepta Basu, Nickie Andescavage, Catherine Limperopoulo. Regional homogeneity as a marker of sensory cortex dysmaturity in preterm infants. iScience. vol 27. issue 5. 2024-04-26. PMID:38665205. |
finally, exploratory analyses showed that the reduction of reho in the primary auditory cortex of preterm infants is related to increased risk of autism at 18 months. |
2024-04-26 |
2024-04-28 |
Not clear |
| Gleb Bezgin, John D Lewis, Vladimir S Fonov, D Louis Collins, Alan C Evan. Atypical co-development of the thalamus and cortex in autism: Evidence from age-related white-gray contrast change. Human brain mapping. vol 45. issue 5. 2024-03-27. PMID:38533724. |
atypical co-development of the thalamus and cortex in autism: evidence from age-related white-gray contrast change. |
2024-03-27 |
2024-03-29 |
human |
| Gleb Bezgin, John D Lewis, Vladimir S Fonov, D Louis Collins, Alan C Evan. Atypical co-development of the thalamus and cortex in autism: Evidence from age-related white-gray contrast change. Human brain mapping. vol 45. issue 5. 2024-03-27. PMID:38533724. |
recent studies have shown that white-gray contrast (wgc) of either cortical or subcortical gray matter provides for accurate predictions of age in typically developing (td) children, and that, at least for the cortex, it changes differently with age in subjects with autism spectrum disorder (asd) compared to their td peers. |
2024-03-27 |
2024-03-29 |
human |
| Jarek Wegiel, Kathryn Chadman, Eric London, Thomas Wisniewski, Jerzy Wegie. Contribution of the serotonergic system to developmental brain abnormalities in autism spectrum disorder. Autism research : official journal of the International Society for Autism Research. 2024-03-19. PMID:38500252. |
in autism, defects in regulation of neuronal growth are the most frequent and ubiquitous developmental changes associated with impaired neuron differentiation, smaller size, distorted shape, loss of spatial orientation, and distortion of cortex organization. |
2024-03-19 |
2024-03-21 |
human |
| Xianjing Li, Miaomiao Jiang, Liyang Zhao, Kang Yang, Tianlan Lu, Dai Zhang, Jun Li, Lifang Wan. Relationship between autism and brain cortex surface area: genetic correlation and a two-sample Mendelian randomization study. BMC psychiatry. vol 24. issue 1. 2024-01-23. PMID:38263034. |
relationship between autism and brain cortex surface area: genetic correlation and a two-sample mendelian randomization study. |
2024-01-23 |
2024-01-26 |
Not clear |
| Xianjing Li, Miaomiao Jiang, Liyang Zhao, Kang Yang, Tianlan Lu, Dai Zhang, Jun Li, Lifang Wan. Relationship between autism and brain cortex surface area: genetic correlation and a two-sample Mendelian randomization study. BMC psychiatry. vol 24. issue 1. 2024-01-23. PMID:38263034. |
alterations in surface area (sa) in specific regions of the cortex have been reported in many individuals with autism spectrum disorder (asd), however, the genetic background between asd and sa is still unclear. |
2024-01-23 |
2024-01-26 |
Not clear |
| Leong Tung Ong, Si Wei David Fa. Morphological and Functional Changes of Cerebral Cortex in Autism Spectrum Disorder. Innovations in clinical neuroscience. vol 20. issue 10-12. 2024-01-09. PMID:38193097. |
morphological and functional changes of cerebral cortex in autism spectrum disorder. |
2024-01-09 |
2024-01-10 |
Not clear |
| Sébastien Delhaye, Marielle Jarjat, Asma Boulksibat, Clara Sanchez, Alessandra Tempio, Andrei Turtoi, Mauro Giorgi, Sandra Lacas-Gervais, Gabriele Baj, Carole Rovere, Viviana Trezza, Manuela Pellegrini, Thomas Maurin, Enzo Lalli, Barbara Bardon. Defects in AMPAR trafficking and microglia activation underlie socio-cognitive deficits associated to decreased expression of phosphodiesterase 2 a. Neurobiology of disease. 2023-12-28. PMID:38154608. |
in cerebral cortex and hippocampus, pde2a expression level is upregulated in fmr1-ko mice, a model of the fragile x syndrome (fxs), the most common form of inherited intellectual disability (id) and autism spectrum disorder (asd). |
2023-12-28 |
2023-12-31 |
mouse |
| Han Chin Wang, Daniel E Feldma. Degraded tactile coding in the Cntnap2 mouse model of autism. bioRxiv : the preprint server for biology. 2023-10-09. PMID:37808857. |
atypical sensory processing in autism involves altered neural circuit function and neural coding in sensory cortex, but the nature of coding disruption is poorly understood. |
2023-10-09 |
2023-10-15 |
mouse |
| Samir Rahman, Pengfei Dong, Pasha Apontes, Michael B Fernando, Roman Kosoy, Kayla G Townsley, Kiran Girdhar, Jaroslav Bendl, Zhiping Shao, Ruth Misir, Nadia Tsankova, Steven P Kleopoulos, Kristen J Brennand, John F Fullard, Panos Rousso. Lineage specific 3D genome structure in the adult human brain and neurodevelopmental changes in the chromatin interactome. Nucleic acids research. 2023-10-09. PMID:37811875. |
importantly, differential loops in the fetal cortex are associated with autism gwas loci, suggesting a neuropsychiatric disease mechanism affecting the chromatin interactome. |
2023-10-09 |
2023-10-15 |
human |
| Janusz Frackowiak, Bozena Mazur-Koleck. Intraneuronal accumulation of amyloid-β peptides as the pathomechanism linking autism and its co-morbidities: epilepsy and self-injurious behavior - the hypothesis. Frontiers in molecular neuroscience. vol 16. 2023-06-12. PMID:37305553. |
autism spectrum disorder (asd) is associated with enhanced processing of amyloid-β precursor protein (app) by secretase-α, higher blood levels of sappα and intraneuronal accumulation of n-terminally truncated aβ peptides in the brain cortex - mainly in the gabaergic neurons expressing parvalbumin - and subcortical structures. |
2023-06-12 |
2023-08-14 |
Not clear |
| Lisa S Knaus, Bernadette Basilico, Daniel Malzl, Maria Gerykova Bujalkova, Mateja Smogavec, Lena A Schwarz, Sarah Gorkiewicz, Nicole Amberg, Florian M Pauler, Christian Knittl-Frank, Marianna Tassinari, Nuno Maulide, Thomas Rülicke, Jörg Menche, Simon Hippenmeyer, Gaia Novarin. Large neutral amino acid levels tune perinatal neuronal excitability and survival. Cell. 2023-03-30. PMID:36996814. |
inspired by the discovery that mutations in slc7a5, a transporter of metabolically essential large neutral amino acids (lnaas), lead to autism, we employed metabolomic profiling to study the metabolic states of the cerebral cortex across different developmental stages. |
2023-03-30 |
2023-08-14 |
Not clear |
| Christopher J Handwerk, Collin J Denzler, Anna R Kalinowski, Hollyn N Cook, Hilda V Rodriguez, Katherine M Bland, Cooper A Brett, Brian D Swinehart, Elizabeth C Vinson, George S Vida. Integrin β3 regulates apical dendritic morphology of pyramidal neurons throughout hippocampal CA3. Hippocampus. 2023-03-27. PMID:36967540. |
itgb3 is a potential autism susceptibility gene that regulates dendritic morphology in the cerebral cortex in a cell-specific manner. |
2023-03-27 |
2023-08-14 |
Not clear |
| Brie Wamsley, Lucy Bicks, Yuyan Cheng, Riki Kawaguchi, Diana Quintero, Jennifer Grundman, Jianyin Liu, Shaohua Xiao, Natalie Hawken, Michael Margolis, Samantha Mazariegos, Daniel H Geschwin. Molecular cascades and cell-type specific signatures in ASD revealed by single cell genomics. bioRxiv : the preprint server for biology. 2023-03-22. PMID:36945369. |
studies over the last decade have demonstrated robust evidence of convergent transcriptional and epigenetic profiles in post-mortem cerebral cortex from individuals with autism spectrum disorder (asd). |
2023-03-22 |
2023-08-14 |
human |
| Yifei Yang, Sam A Booker, James M Clegg, Idoia Quintana-Urzainqui, Anna Sumera, Zrinko Kozic, Owen Dando, Sandra Martin Lorenzo, Yann Herault, Peter C Kind, David J Price, Thomas Prat. Identifying foetal forebrain interneurons as a target for monogenic autism risk factors and the polygenic 16p11.2 microdeletion. BMC neuroscience. vol 24. issue 1. 2023-01-19. PMID:36658491. |
the balance between excitatory and inhibitory neurons in the cerebral cortex is hypothesised to be critical for the aetiology of autism making improved understanding of how risk factors impact on the development of these cells an important area of research. |
2023-01-19 |
2023-08-14 |
human |
| Stefanie Schelinski, Katharina von Kriegstei. Responses in left inferior frontal gyrus are altered for speech-in-noise processing, but not for clear speech in autism. Brain and behavior. 2022-12-28. PMID:36575611. |
here, we tested whether responses in these cerebral cortex regions are altered in speech-in-noise perception in autism. |
2022-12-28 |
2023-08-14 |
Not clear |
| Can Cao, Qi Li, Yanping Chen, Mingyang Zou, Caihong Sun, Xiangning Li, Lijie W. Untargeted Metabolomic Analysis Reveals the Metabolic Disturbances and Exacerbation of Oxidative Stress in the Cerebral Cortex of a BTBR Mouse Model of Autism. Journal of molecular neuroscience : MN. 2022-12-27. PMID:36574152. |
untargeted metabolomic analysis reveals the metabolic disturbances and exacerbation of oxidative stress in the cerebral cortex of a btbr mouse model of autism. |
2022-12-27 |
2023-08-14 |
mouse |
| Can Cao, Qi Li, Yanping Chen, Mingyang Zou, Caihong Sun, Xiangning Li, Lijie W. Untargeted Metabolomic Analysis Reveals the Metabolic Disturbances and Exacerbation of Oxidative Stress in the Cerebral Cortex of a BTBR Mouse Model of Autism. Journal of molecular neuroscience : MN. 2022-12-27. PMID:36574152. |
emerging evidence supports that abnormal metabolites in the cerebral cortex of a btbr mouse model of autism are involved in the pathogenesis of autism. |
2022-12-27 |
2023-08-14 |
mouse |
| Can Cao, Qi Li, Yanping Chen, Mingyang Zou, Caihong Sun, Xiangning Li, Lijie W. Untargeted Metabolomic Analysis Reveals the Metabolic Disturbances and Exacerbation of Oxidative Stress in the Cerebral Cortex of a BTBR Mouse Model of Autism. Journal of molecular neuroscience : MN. 2022-12-27. PMID:36574152. |
notably, exacerbation of the oxidative stress response caused by differential prooxidant metabolites led to alteration of antioxidative systems in the cerebral cortex and resulted in mitochondrial dysfunction, further leading to abnormal energy metabolism as an etiological mechanism of autism. |
2022-12-27 |
2023-08-14 |
mouse |
| Can Cao, Qi Li, Yanping Chen, Mingyang Zou, Caihong Sun, Xiangning Li, Lijie W. Untargeted Metabolomic Analysis Reveals the Metabolic Disturbances and Exacerbation of Oxidative Stress in the Cerebral Cortex of a BTBR Mouse Model of Autism. Journal of molecular neuroscience : MN. 2022-12-27. PMID:36574152. |
a central role of abnormal metabolites in neurological functions associated with behavioral outcomes and disturbance of sulfur metabolism and carnitine biosynthesis were found in the cerebral cortex of btbr mice, which helped increase our understanding for exploring the pathological mechanism of autism. |
2022-12-27 |
2023-08-14 |
mouse |