| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dmitry Velmeshev, Marco Magistri, Emilia Maria Cristina Mazza, Patrick Lally, Nathalie Khoury, Evan Ross D'Elia, Silvio Bicciato, Mohammad Ali Faghih. Cell-Type-Specific Analysis of Molecular Pathology in Autism Identifies Common Genes and Pathways Affected Across Neocortical Regions. Molecular neurobiology. vol 57. issue 5. 2021-02-03. PMID:32008165. |
to gain information about cell-type specificity of the dysregulated genes, we analyzed single-nuclei rna sequencing data of adult human cortex and intersected cell-type-specific gene signatures with genes dysregulated in autism in specific cortical regions. |
2021-02-03 |
2023-08-13 |
human |
| Rohit Marawar, Neil Klinger, Sarah I Tarbox-Berry, Sandeep Mittal, Aashit K Sha. Atypical representation of sensorimotor cortex in a patient with autism and epilepsy confirmed by direct electrocortical stimulation. Epilepsy & behavior reports. vol 15. 2021-01-14. PMID:33437958. |
atypical representation of sensorimotor cortex in a patient with autism and epilepsy confirmed by direct electrocortical stimulation. |
2021-01-14 |
2023-08-13 |
Not clear |
| Shin-Hwa Tsai, Chih-Yu Tsao, Li-Jen Le. Altered White Matter and Layer VIb Neurons in Heterozygous Frontiers in neuroanatomy. vol 14. 2021-01-02. PMID:33384588. |
subplate neurons, the earliest generated neurons in the developing cortex have also been associated with schizophrenia and autism. |
2021-01-02 |
2023-08-13 |
Not clear |
| Jessica L Huebschman, Kitzia S Corona, Yuhong Guo, Laura N Smit. The Fragile X Mental Retardation Protein Regulates Striatal Medium Spiny Neuron Synapse Density and Dendritic Spine Morphology. Frontiers in molecular neuroscience. vol 13. 2020-10-06. PMID:33013316. |
loss of fmrp, as in fragile x syndrome (fxs), is a leading monogenic cause of autism and results in altered structural and functional synaptic plasticity, widely described in the hippocampus and cortex. |
2020-10-06 |
2023-08-13 |
Not clear |
| Qianling Hou, Yan Wang, Yingbo Li, Di Chen, Feng Yang, Shali Wan. A Developmental Study of Abnormal Behaviors and Altered GABAergic Signaling in the VPA-Treated Rat Model of Autism. Frontiers in behavioral neuroscience. vol 12. 2020-10-01. PMID:30186123. |
our findings indicate an impaired gabaergic system could be a major etiological factor occurring in the cerebral cortex, hc and cerebellum of human cases of autism, which suggests enhancement of gaba signaling would be a promising therapeutic target for its treatment. |
2020-10-01 |
2023-08-13 |
human |
| Chang Zhou, Sumei Yan, Shaowen Qian, Zhaoqun Wang, Zhiyue Shi, Ying Xiong, Yi Zho. Atypical Response Properties of the Auditory Cortex of Awake MECP2-Overexpressing Mice. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31133783. |
our findings suggest that mecp2 overexpression can cause the auditory cortex to have atypical response properties, an implication that could be helpful for further understanding the nature of auditory deficits in autism. |
2020-10-01 |
2023-08-13 |
mouse |
| Ramit Sharma, Saloni Rahi, Sidharth Meha. Neuroprotective potential of solanesol in intracerebroventricular propionic acid induced experimental model of autism: Insights from behavioral and biochemical evidence. Toxicology reports. vol 6. 2020-10-01. PMID:31763180. |
neuropathological hallmarks that associated with autism are mitochondrial dysfunction, oxidative stress, neuroinflammation, neuro-excitation, abnormal synapse formation, overexpression of glial cells in specific brain regions like cerebellum, cerebral cortex, amygdala, and hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Josephina Hillus, Rachel Moseley, Stefan Roepke, Bettina Moh. Action Semantic Deficits and Impaired Motor Skills in Autistic Adults Without Intellectual Impairment. Frontiers in human neuroscience. vol 13. 2020-09-30. PMID:31404247. |
interestingly, in individuals with autism spectrum disorder (asd), semantic processing of action and emotion words seems to be impaired and is associated with hypoactivity of the motor cortex during semantic processing. |
2020-09-30 |
2023-08-13 |
human |
| Branka Hrvoj-Mihic, Kari L Hanson, Caroline H Lew, Lisa Stefanacci, Bob Jacobs, Ursula Bellugi, Katerina Semendefer. Basal Dendritic Morphology of Cortical Pyramidal Neurons in Williams Syndrome: Prefrontal Cortex and Beyond. Frontiers in neuroscience. vol 11. 2020-09-29. PMID:28848376. |
although this study utilized tissue held in formalin for a prolonged period of time and the number of neurons available for analysis was limited, our findings indicate that ws cortex, similar to that in other neurodevelopmental disorders such as down syndrome, rett syndrome, fragile x, and idiopathic autism, has altered morphology of basal dendrites on pyramidal neurons, which appears more prominent in selected areas of the pfc. |
2020-09-29 |
2023-08-13 |
human |
| Jia Wang, Kuang Fu, Lei Chen, Xujun Duan, Xiaonan Guo, Heng Chen, Qiong Wu, Wei Xia, Lijie Wu, Huafu Che. Increased Gray Matter Volume and Resting-State Functional Connectivity in Somatosensory Cortex and their Relationship with Autistic Symptoms in Young Boys with Autism Spectrum Disorder. Frontiers in physiology. vol 8. 2020-09-29. PMID:28861001. |
increased gray matter volume and resting-state functional connectivity in somatosensory cortex and their relationship with autistic symptoms in young boys with autism spectrum disorder. |
2020-09-29 |
2023-08-13 |
Not clear |
| Manuel F Casanova, Mohamed Shaban, Mohammed Ghazal, Ayman S El-Baz, Emily L Casanova, Ioan Opris, Estate M Sokhadz. Effects of Transcranial Magnetic Stimulation Therapy on Evoked and Induced Gamma Oscillations in Children with Autism Spectrum Disorder. Brain sciences. vol 10. issue 7. 2020-09-28. PMID:32635201. |
the results suggest that gamma oscillations may provide a biomarker reflective of the excitatory/inhibitory balance of the cortex and a putative outcome measure for interventions in autism. |
2020-09-28 |
2023-08-13 |
human |
| Ernest V Pedapati, Lindsey N Mooney, Steve W Wu, Craig A Erickson, John A Sweeney, Rebecca C Shaffer, Paul S Horn, Logan K Wink, Donald L Gilber. Motor cortex facilitation: a marker of attention deficit hyperactivity disorder co-occurrence in autism spectrum disorder. Translational psychiatry. vol 9. issue 1. 2020-09-02. PMID:31723120. |
motor cortex facilitation: a marker of attention deficit hyperactivity disorder co-occurrence in autism spectrum disorder. |
2020-09-02 |
2023-08-13 |
Not clear |
| Timothy P L Roberts, Junko Matsuzaki, Lisa Blaskey, Luke Bloy, J Christopher Edgar, Mina Kim, Matthew Ku, Emily S Kuschner, David Embic. Delayed M50/M100 evoked response component latency in minimally verbal/nonverbal children who have autism spectrum disorder. Molecular autism. vol 10. 2020-06-17. PMID:31428297. |
abnormal auditory neuromagnetic m50 and m100 responses, reflecting primary/secondary auditory cortex processing, have been reported in children who have autism spectrum disorder (asd). |
2020-06-17 |
2023-08-13 |
Not clear |
| Xiang-Zhen Kong, Merel C Postema, Tulio Guadalupe, Carolien de Kovel, Premika S W Boedhoe, Martine Hoogman, Samuel R Mathias, Daan van Rooij, Dick Schijven, David C Glahn, Sarah E Medland, Neda Jahanshad, Sophia I Thomopoulos, Jessica A Turner, Jan Buitelaar, Theo G M van Erp, Barbara Franke, Simon E Fisher, Odile A van den Heuvel, Lianne Schmaal, Paul M Thompson, Clyde Franck. Mapping brain asymmetry in health and disease through the ENIGMA consortium. Human brain mapping. 2020-05-18. PMID:32420672. |
effect sizes were estimated for gray matter asymmetry based on large, international, samples in relation to age, sex, handedness, and brain volume, as well as for three psychiatric disorders: autism spectrum disorder was associated with subtly reduced asymmetry of cortical thickness at regions spread widely over the cortex; pediatric obsessive-compulsive disorder was associated with altered subcortical asymmetry; major depressive disorder was not significantly associated with changes of asymmetry. |
2020-05-18 |
2023-08-13 |
human |
| Jose O Maximo, Rajesh K Kan. Aberrant "deep connectivity" in autism: A cortico-subcortical functional connectivity magnetic resonance imaging study. Autism research : official journal of the International Society for Autism Research. vol 12. issue 3. 2020-04-17. PMID:30624021. |
the goal of this study was to characterize the functional connectivity between cortex and subcortical regions in asd using the autism brain imaging data exchange (abide-ii). |
2020-04-17 |
2023-08-13 |
human |
| Laurie-Anne Sapey-Triomphe, Franck Lamberton, Sandrine Sonié, Jérémie Mattout, Christina Schmit. Tactile hypersensitivity and GABA concentration in the sensorimotor cortex of adults with autism. Autism research : official journal of the International Society for Autism Research. vol 12. issue 4. 2020-04-03. PMID:30632707. |
tactile hypersensitivity and gaba concentration in the sensorimotor cortex of adults with autism. |
2020-04-03 |
2023-08-13 |
Not clear |
| Rafael Romero-Garcia, Varun Warrier, Edward T Bullmore, Simon Baron-Cohen, Richard A I Bethlehe. Synaptic and transcriptionally downregulated genes are associated with cortical thickness differences in autism. Molecular psychiatry. vol 24. issue 7. 2020-03-02. PMID:29483624. |
these genes are also significantly enriched for genes dysregulated in the autism post-mortem cortex (odd ratio (or) = 1.11, p |
2020-03-02 |
2023-08-13 |
Not clear |
| Fumi Masuda, Shinichiro Nakajima, Takahiro Miyazaki, Kazunari Yoshida, Sakiko Tsugawa, Masataka Wada, Kamiyu Ogyu, Paul E Croarkin, Daniel M Blumberger, Zafiris J Daskalakis, Masaru Mimura, Yoshihiro Nod. Motor cortex excitability and inhibitory imbalance in autism spectrum disorder assessed with transcranial magnetic stimulation: a systematic review. Translational psychiatry. vol 9. issue 1. 2020-01-09. PMID:30846682. |
motor cortex excitability and inhibitory imbalance in autism spectrum disorder assessed with transcranial magnetic stimulation: a systematic review. |
2020-01-09 |
2023-08-13 |
Not clear |
| Marta Serati, Giuseppe Delvecchio, Giulia Orsenigo, Gian Mario Mandolini, Matteo Lazzaretti, Elisa Scola, Fabio Triulzi, Paolo Brambill. The Role of the Subplate in Schizophrenia and Autism: A Systematic Review. Neuroscience. vol 408. 2020-01-09. PMID:30930130. |
there is evidence that schizophrenia and autism may be determined by developmental defects in the cortex or cortical circuitry during the earliest stages of pregnancy. |
2020-01-09 |
2023-08-13 |
Not clear |
| Marianna K Keaveney, Hua-An Tseng, Tina L Ta, Howard J Gritton, Heng-Ye Man, Xue Ha. A MicroRNA-Based Gene-Targeting Tool for Virally Labeling Interneurons in the Rodent Cortex. Cell reports. vol 24. issue 2. 2019-11-07. PMID:29996091. |
our interneuron-targeting, microrna-guided neuron tag, "gaba magnet," achieves >95% interneuron selective labeling in the mouse cortex, including in a murine model of autism and also some preferential labeling of interneurons in the rat brain. |
2019-11-07 |
2023-08-13 |
mouse |