| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tuğba Ertem, Onur Uysa. Differentiation of neural stem cells from human olfactory mucosa into dopaminergic neuron-like cells. IUBMB life. 2024-04-25. PMID:38662920. |
the aim of this study was to develop an alternative treatment method for neurodegenerative diseases with dopaminergic neuron loss such as parkinson's disease by differentiating cells obtained from human olfactory mucosa-derived neural stem cells (hom-nscs) with neurotrophic agents in vitro. |
2024-04-25 |
2024-04-28 |
human |
| b' Martina Kovalov\\xc3\\xa1, Nikol Gottfriedov\\xc3\\xa1, Eva Mr\\xc3\\xa1zkov\\xc3\\xa1, Vladim\\xc3\\xadr Janout, Jana Janoutov\\xc3\\xa. Cognitive impairment, neurodegenerative disorders, and olfactory impairment: A literature review. Otolaryngologia polska = The Polish otolaryngology. vol 78. issue 2. 2024-04-16. PMID:38623856.' |
even though smell tests are able to detect olfactory loss caused by neurodegenerative diseases, they cannot reliably distinguish between certain diseases.</br> <br><b>conclusions:</b> in individuals with cognitive impairment or neurodegenerative diseases, olfactory assessment has repeatedly been reported to be used for early diagnosis, but not for differential diagnosis.</br>. |
2024-04-16 |
2024-04-18 |
Not clear |
| Rafael Franco, Claudia Garrigós, Jaume Lill. The Olfactory Trail of Neurodegenerative Diseases. Cells. vol 13. issue 7. 2024-04-12. PMID:38607054. |
the olfactory trail of neurodegenerative diseases. |
2024-04-12 |
2024-04-14 |
human |
| Rafael Franco, Claudia Garrigós, Jaume Lill. The Olfactory Trail of Neurodegenerative Diseases. Cells. vol 13. issue 7. 2024-04-12. PMID:38607054. |
alterations in olfactory functions are proposed as possible early biomarkers of neurodegenerative diseases. |
2024-04-12 |
2024-04-14 |
human |
| Rafael Franco, Claudia Garrigós, Jaume Lill. The Olfactory Trail of Neurodegenerative Diseases. Cells. vol 13. issue 7. 2024-04-12. PMID:38607054. |
by unraveling how olfactory receptor activation is involved in neurodegeneration and identifying links between olfactory structures and neuronal death, valuable information could be gained for early diagnosis and intervention strategies in neurodegenerative diseases. |
2024-04-12 |
2024-04-14 |
human |
| Khamis T Suleiman, Richard G Chiu, Sharmilee M Nyenhuis, Kamal Eldeirawi, Victoria S Le. Association of alcohol use with olfactory function among older adults. American journal of otolaryngology. vol 45. issue 4. 2024-04-04. PMID:38574516. |
olfactory dysfunction (od) has been recognized as an early biomarker for neurodegenerative diseases. |
2024-04-04 |
2024-04-07 |
Not clear |
| Tommaso Schirinzi, Daniela Maftei, Riccardo Maurizi, Maria Albanese, Clara Simonetta, Roberta Bovenzi, Jacopo Bissacco, Davide Mascioli, Laura Boffa, Maria Grazia Di Certo, Francesca Gabanella, Beatrice Francavilla, Stefano Di Girolamo, Nicola Biagio Mercuri, Francesco Maria Passali, Roberta Lattanzi, Cinzia Severin. Post-COVID-19 Hyposmia Does Not Exhibit Main Neurodegeneration Markers in the Olfactory Pathway. Molecular neurobiology. 2024-04-03. PMID:38570429. |
however, as many neurodegenerative diseases present with smell impairment at onset, it may theoretically reflect degeneration within the central olfactory circuits. |
2024-04-03 |
2024-04-06 |
Not clear |
| Laia Ramos-Casademont, Daniel Martin-Jimenez, Brenda Villarreal-Garza, Serafín Sánchez-Gomez, María Amparo Callejon-Lebli. The Value of Subjective Olfactometry as a Predictive Biomarker of Neurodegenerative Diseases: A Systematic Review. Life (Basel, Switzerland). vol 14. issue 3. 2024-03-28. PMID:38541625. |
olfactory disorders (ods) are reported to be an early non-motor sign before the onset of deterioration in neurodegenerative diseases (nds) such as alzheimer's and parkinson's. |
2024-03-28 |
2024-03-30 |
Not clear |
| Eqrem Rusi, Fiorenza Pennacchia, Wael Abu Ruqa, Giuseppina Talarico, Giuseppe Bruno, Antonio Minni, Christian Barbat. Proteoform Analysis of the Human Olfactory System: A Window into Neurodegenerative Diseases. Proteomes. vol 12. issue 1. 2024-03-27. PMID:38535507. |
proteoform analysis of the human olfactory system: a window into neurodegenerative diseases. |
2024-03-27 |
2024-03-29 |
human |
| Kefu Liu, Ailikemu Aierken, Mengyao Liu, Nazakat Parhat, Wei Kong, Xingyu Yin, Gang Liu, Ding Yu, Jie Hong, Junjun Ni, Zhenzhen Quan, Xiaoyun Liu, Simei Ji, Jian Mao, Weijun Peng, Chao Chen, Yan Yan, Hong Qin. The decreased astrocyte-microglia interaction reflects the early characteristics of Alzheimer's disease. iScience. vol 27. issue 3. 2024-03-08. PMID:38455972. |
alzheimer's disease (ad) is the most common neurodegenerative disease often associated with olfactory dysfunction. |
2024-03-08 |
2024-03-10 |
mouse |
| Dongming Liu, Jiaming Lu, Liangpeng Wei, Mei Yao, Huiquan Yang, Pin Lv, Haoyao Wang, Yajing Zhu, Zhengyang Zhu, Xin Zhang, Jiu Chen, Qing X Yang, Bing Zhan. Olfactory deficit: a potential functional marker across the Alzheimer's disease continuum. Frontiers in neuroscience. vol 18. 2024-03-04. PMID:38435057. |
despite the challenges and limitations of existing research, olfactory dysfunction has demonstrated its value in assessing neurodegenerative diseases and may serve as an early indicator of ad in the future. |
2024-03-04 |
2024-03-06 |
Not clear |
| Linda L Cha. Olfactory and cognitive decrements in 1991 Gulf War veterans with gulf war illness/chronic multisymptom illness. Environmental health : a global access science source. vol 23. issue 1. 2024-01-30. PMID:38291474. |
because olfactory deficit is a prodromal symptom of neurodegenerative diseases like parkinson's and alzheimer's disease, and because we previously reported suggestive evidence that deployed gw veterans may be at increased risk for mild cognitive impairment (mci) and dementia, the current study examined the relationship between olfactory and cognitive function in deployed gw veterans. |
2024-01-30 |
2024-02-02 |
Not clear |
| Hae Ryong Lee, Kyung Soo Kim, Hyun Jin Mi. Development of a Digital Olfactory Function Test: A Preliminary Study. Life (Basel, Switzerland). vol 14. issue 1. 2024-01-23. PMID:38255690. |
olfactory dysfunction is associated with conditions such as neurodegenerative diseases, diabetes, obesity, autoimmune diseases, mental illnesses, and upper-airway-related diseases. |
2024-01-23 |
2024-01-25 |
human |
| Kyung Soo Kim, Hyun Jin Mi. A case of olfactory neuroblastoma that presented with olfactory dysfunction after a COVID-19 diagnosis. Heliyon. vol 9. issue 11. 2023-12-06. PMID:38053881. |
olfactory dysfunction is associated with conditions such as respiratory tract infections, trauma, sinonasal diseases, and neurodegenerative diseases. |
2023-12-06 |
2023-12-10 |
Not clear |
| Mengxue Liu, Nan Jiang, Chunlian Qin, Yingying Xue, Jianguo Wu, Yong Qiu, Qunchen Yuan, Changming Chen, Liquan Huang, Liujing Zhuang, Ping Wan. Multimodal spatiotemporal monitoring of basal stem cell-derived organoids reveals progression of olfactory dysfunction in Alzheimer's disease. Biosensors & bioelectronics. vol 246. 2023-11-28. PMID:38016198. |
olfactory dysfunction (od) is a highly prevalent symptom and an early sign of neurodegenerative diseases in humans. |
2023-11-28 |
2023-12-07 |
mouse |
| Li-Peng Zhang, Jun-Xiang Liao, Yi-Yi Liu, Hong-Lang Luo, Wen-Jun Zhan. Potential therapeutic effect of olfactory ensheathing cells in neurological diseases: neurodegenerative diseases and peripheral nerve injuries. Frontiers in immunology. vol 14. 2023-11-02. PMID:37915589. |
potential therapeutic effect of olfactory ensheathing cells in neurological diseases: neurodegenerative diseases and peripheral nerve injuries. |
2023-11-02 |
2023-11-08 |
Not clear |
| Adam Bothwell, Susan M Resnick, Luigi Ferrucci, Qu Tia. Associations of olfactory function with brain structural and functional outcomes. A systematic review. Ageing research reviews. 2023-11-01. PMID:37913831. |
olfactory dysfunction is also one of the earliest features of neurodegenerative disease. |
2023-11-01 |
2023-11-08 |
Not clear |
| Yingying Gu, Jiaying Zhang, Xinru Zhao, Wenyuan Nie, Xiaole Xu, Mingxuan Liu, Xiaoling Zhan. Olfactory dysfunction and its related molecular mechanisms in Parkinson's disease. Neural regeneration research. vol 19. issue 3. 2023-09-18. PMID:37721288. |
on the basis of the findings of clinical olfactory function tests and animal model experiments as well as neurotransmitter expression levels, we further characterize the relationship between olfactory dysfunction and neurodegenerative diseases as well as the molecular mechanisms underlying olfactory dysfunction in the pathology of early-stage parkinson's disease. |
2023-09-18 |
2023-10-07 |
Not clear |
| Someshbabu Ramesh Babu, Harshith Hosahalli Shekara, Ashish Kumar Sahoo, Pyda Venkata Harsha Vardhan, Nitheesh Thiruppathi, Madhugiri Prakash Venkates. Intranasal nanoparticulate delivery systems for neurodegenerative disorders: a review. Therapeutic delivery. 2023-09-11. PMID:37691577. |
therefore, intranasal drug-delivery systems show potential for treating neurodegenerative diseases through trigeminal or olfactory pathways, which can significantly improve patient outcomes. |
2023-09-11 |
2023-10-07 |
Not clear |
| Chunyu Cai, Qihui Luo, Lanlan Jia, Yu Xia, Xinting Lan, Xiaoli Wei, Shuai Shi, Yucong Liu, Yao Wang, Zongliang Xiong, Riyi Shi, Chao Huang, Zhengli Che. TRIM67 Implicates in Regulating the Homeostasis and Synaptic Development of Mitral Cells in the Olfactory Bulb. International journal of molecular sciences. vol 24. issue 17. 2023-09-09. PMID:37686246. |
in recent years, olfactory dysfunction has attracted increasingly more attention as a hallmark symptom of neurodegenerative diseases (nd). |
2023-09-09 |
2023-10-07 |
mouse |