| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Juan Fernandez-Ruiz, Rosalinda Díaz, Cynthia Hall-Haro, Patricia Vergara, Aldo Fiorentini, Lilia Nuñez, René Drucker-Colín, Adriana Ochoa, Petra Yescas, Astrid Rasmussen, Maria-Elisa Alons. Olfactory dysfunction in hereditary ataxia and basal ganglia disorders. Neuroreport. vol 14. issue 10. 2003-09-26. PMID:12876469. |
first, an olfactory dysfunction has been found in different neurodegenerative diseases, and second, human functional imaging has shown cerebellar activation during olfaction. |
2003-09-26 |
2023-08-12 |
human |
| Elan D Louis, Steven M Bromley, Eva C Jurewicz, Dryden Watne. Olfactory dysfunction in essential tremor: a deficit unrelated to disease duration or severity. Neurology. vol 59. issue 10. 2002-12-17. PMID:12451211. |
because olfactory dysfunction is a feature of neurodegenerative diseases, the authors hypothesized that it would be present in essential tremor. |
2002-12-17 |
2023-08-12 |
human |
| R L Dot. Olfaction. Annual review of psychology. vol 52. 2001-07-12. PMID:11148312. |
the latter developments have led to the proliferation of standardized olfactory testing in laboratories and clinics, and to the discovery that smell loss is among the first signs of a number of neurodegenerative diseases, including alzheimer's disease and idiopathic parkinson's disease. |
2001-07-12 |
2023-08-12 |
Not clear |
| E Navarrete, O Prospéro, R Hudson, R Guevar. [Neurovegetative diseases in dementia]. Gaceta medica de Mexico. vol 136. issue 6. 2000-12-28. PMID:11131859. |
affliction of this last area has been suggested to account for the early olfactory dysfunction often shown by patients after the onset of alzheimer and parkinson, leading to the suggestion that olfactory testing could be useful in the early diagnosis of such neurodegenerative diseases. |
2000-12-28 |
2023-08-12 |
Not clear |
| S Parola, P Liberin. Assessing olfaction in the Italian population: methodology and clinical application. Italian journal of neurological sciences. vol 20. issue 5. 2000-08-29. PMID:10933437. |
in recent years, particular emphasis has been attributed to the early and severe olfactory impairment in neurodegenerative diseases, such as alzheimer's dementia and parkinson's disease. |
2000-08-29 |
2023-08-12 |
Not clear |
| Z K Wszolek, K Markopoulo. Olfactory dysfunction in Parkinson's disease. Clinical neuroscience (New York, N.Y.). vol 5. issue 2. 2000-05-09. PMID:10785834. |
olfactory dysfunction is also associated with other neurodegenerative diseases such as alzheimer's disease (ad), huntington's disease (hd), as well as with normal aging. |
2000-05-09 |
2023-08-12 |
Not clear |
| Z K Wszolek, K Markopoulo. Olfactory dysfunction in Parkinson's disease. Clinical neuroscience (New York, N.Y.). vol 5. issue 2. 2000-05-09. PMID:10785834. |
the neuropathological changes observed in the olfactory system in pd and other neurodegenerative diseases appear to be disease-specific, raising the possibility that olfactory dysfunction may be the result of a central rather than a peripheral process. |
2000-05-09 |
2023-08-12 |
Not clear |
| Z K Wszolek, K Markopoulo. Olfactory dysfunction in Parkinson's disease. Clinical neuroscience (New York, N.Y.). vol 5. issue 2. 2000-05-09. PMID:10785834. |
the cellular and molecular mechanisms underlying olfactory dysfunction in pd and other neurodegenerative diseases remain unknown. |
2000-05-09 |
2023-08-12 |
Not clear |
| J E Duda, U Shah, S E Arnold, V M Lee, J Q Trojanowsk. The expression of alpha-, beta-, and gamma-synucleins in olfactory mucosa from patients with and without neurodegenerative diseases. Experimental neurology. vol 160. issue 2. 2000-01-14. PMID:10619569. |
the expression of alpha-, beta-, and gamma-synucleins in olfactory mucosa from patients with and without neurodegenerative diseases. |
2000-01-14 |
2023-08-12 |
human |
| A S Bacon Moore, J S Paulsen, C Murph. A test of odor fluency in patients with Alzheimer's and Huntington's disease. Journal of clinical and experimental neuropsychology. vol 21. issue 3. 1999-10-21. PMID:10474173. |
our results suggest that tests of odor memory show differential performance in healthy and demented patients, leading to the suggestion that tests of olfactory functioning may be useful in detection and diagnosis of neurodegenerative disease. |
1999-10-21 |
2023-08-12 |
human |
| N E Rawson, G Gomez, B Cowart, D Restrep. The use of olfactory receptor neurons (ORNs) from biopsies to study changes in aging and neurodegenerative diseases. Annals of the New York Academy of Sciences. vol 855. 1999-02-24. PMID:9929674. |
a gradual loss of olfactory capability with age and in a number of neurodegenerative diseases is common, and mechanisms underlying these losses are not understood. |
1999-02-24 |
2023-08-12 |
human |
| J E Ahlskog, S C Waring, R C Petersen, C Esteban-Santillan, U K Craig, P C O'Brien, M F Plevak, L T Kurlan. Olfactory dysfunction in Guamanian ALS, parkinsonism, and dementia. Neurology. vol 51. issue 6. 1998-12-30. PMID:9855521. |
to assess whether olfactory deficits are present in the general guamanian chamorro population and to evaluate olfaction in each of the four neurodegenerative disease syndromes of guam: als, pure parkinsonism, pure dementia, and the combined parkinsonism-dementia complex (pdc). |
1998-12-30 |
2023-08-12 |
Not clear |
| R I Mesholam, P J Moberg, R N Mahr, R L Dot. Olfaction in neurodegenerative disease: a meta-analysis of olfactory functioning in Alzheimer's and Parkinson's diseases. Archives of neurology. vol 55. issue 1. 1998-02-06. PMID:9443714. |
olfaction in neurodegenerative disease: a meta-analysis of olfactory functioning in alzheimer's and parkinson's diseases. |
1998-02-06 |
2023-08-12 |
Not clear |
| R L Dot. Studies of human olfaction from the University of Pennsylvania Smell and Taste Center. Chemical senses. vol 22. issue 5. 1997-12-18. PMID:9363356. |
a brief discussion of the strengths and weaknesses of the olfactory vector hypothesis for neurodegenerative diseases is also presented. |
1997-12-18 |
2023-08-12 |
human |
| K Markopoulou, K W Larsen, E K Wszolek, M A Denson, A E Lang, R F Pfeiffer, Z K Wszole. Olfactory dysfunction in familial parkinsonism. Neurology. vol 49. issue 5. 1997-12-08. PMID:9371905. |
the appearance of olfactory dysfunction soon after disease onset raises the possibility that it is part of the neurodegenerative disease process. |
1997-12-08 |
2023-08-12 |
Not clear |
| D Restrepo, Y Okada, J H Teeter, L D Lowry, B Cowart, J G Bran. Human olfactory neurons respond to odor stimuli with an increase in cytoplasmic Ca2+. Biophysical journal. vol 64. issue 6. 1993-10-13. PMID:8369416. |
in addition, the study of human olfaction is relevant to a number of medical problems that result in olfactory dysfunction, which can affect nutritional state, and to the study of the etiology of neurodegenerative diseases which manifest themselves in the olfactory epithelium. |
1993-10-13 |
2023-08-12 |
human |
| R L Doty, D P Perl, J C Steele, K M Chen, J D Pierce, P Reyes, L T Kurlan. Olfactory dysfunction in three neurodegenerative diseases. Geriatrics. vol 46 Suppl 1. 1991-10-21. PMID:1894145. |
olfactory dysfunction in three neurodegenerative diseases. |
1991-10-21 |
2023-08-11 |
Not clear |