| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aaron Sathyanesan, Joy Zhou, Joseph Scafidi, Detlef H Heck, Roy V Sillitoe, Vittorio Gall. Emerging connections between cerebellar development, behaviour and complex brain disorders. Nature reviews. Neuroscience. vol 20. issue 5. 2019-12-16. PMID:30923348. |
as the cerebellum is critical for motor behaviour, it is not surprising that most neurodevelopmental disorders share motor deficits as a common sequela. |
2019-12-16 |
2023-08-13 |
human |
| Aaron Sathyanesan, Joy Zhou, Joseph Scafidi, Detlef H Heck, Roy V Sillitoe, Vittorio Gall. Emerging connections between cerebellar development, behaviour and complex brain disorders. Nature reviews. Neuroscience. vol 20. issue 5. 2019-12-16. PMID:30923348. |
more recently, evidence indicates that major neurodevelopmental disorders such as intellectual disability, autism spectrum disorder, attention-deficit hyperactivity disorder and down syndrome have potential links to abnormal cerebellar development. |
2019-12-16 |
2023-08-13 |
human |
| Hassan Marzban, Mario Manto, Jean Marian. Cerebellum: from Development to Disease-the 8th International Symposium of the Society for Research on the Cerebellum and Ataxias. Cerebellum (London, England). vol 17. issue 1. 2019-11-20. PMID:29349629. |
the main theme of the 8th international symposium was "development of the cerebellum and neurodevelopmental disorders." |
2019-11-20 |
2023-08-13 |
Not clear |
| Justin R Bourgeois, Russell J Ferlan. Loss of the neurodevelopmental Joubert syndrome causing protein, Ahi1, causes motor and muscle development delays independent of central nervous system involvement. Developmental biology. vol 448. issue 1. 2019-10-23. PMID:30695685. |
joubert syndrome (jbts) is a predominantly autosomal recessive neurodevelopmental disorder that presents with characteristic malformations of the cerebellar vermis, superior cerebellar peduncles and midbrain in humans. |
2019-10-23 |
2023-08-13 |
mouse |
| Michela Lupo, Giusy Olivito, Libera Siciliano, Marcella Masciullo, Marco Bozzali, Marco Molinari, Maria Leggi. Development of a Psychiatric Disorder Linked to Cerebellar Lesions. Cerebellum (London, England). vol 17. issue 4. 2019-07-23. PMID:29460204. |
cerebellar dysfunction plays a critical role in neurodevelopmental disorders with long-term behavioral and neuropsychiatric symptoms. |
2019-07-23 |
2023-08-13 |
Not clear |
| Kim van Dun, Frank V Overwalle, Mario Manto, Peter Marie. Cognitive Impact of Cerebellar Damage: Is There a Future for Cognitive Rehabilitation? CNS & neurological disorders drug targets. vol 17. issue 3. 2019-07-11. PMID:29318978. |
this survey aims to present an overview of the therapeutic interventions available in the literature as a possible treatment for schmahmann's syndrome after cerebellar injury, after posterior fossa surgery in children, and in children with neurodevelopmental disorders. |
2019-07-11 |
2023-08-13 |
Not clear |
| Parthiv Haldipur, Kathleen J Mille. What cerebellar malformations tell us about cerebellar development. Neuroscience letters. vol 688. 2019-02-18. PMID:29802918. |
a better understanding of human cerebellar development will not only facilitate improved diagnosis of human cerebellar malformations, but also lead to the development of treatment paradigms for these important neurodevelopmental disorders. |
2019-02-18 |
2023-08-13 |
mouse |
| Le Xiao, Peter Scheiffel. Local and long-range circuit elements for cerebellar function. Current opinion in neurobiology. vol 48. 2019-02-11. PMID:29316490. |
lastly, we discuss how studies on synapses and circuits of the cerebellum in rodent models of autism-spectrum disorders might contribute to our understanding of the pathophysiology of this class of neurodevelopmental disorders. |
2019-02-11 |
2023-08-13 |
Not clear |
| Lena Constanti. The Role of MicroRNAs in Cerebellar Development and Autism Spectrum Disorder During Embryogenesis. Molecular neurobiology. vol 54. issue 9. 2018-12-17. PMID:27774573. |
their activity during the development of the cerebellum provides a valuable exemplar of how non-coding molecules may assist the development and function of the central nervous system and drive neurodevelopmental disorders. |
2018-12-17 |
2023-08-13 |
Not clear |
| Mercedes Serran. Epigenetic cerebellar diseases. Handbook of clinical neurology. vol 155. 2018-10-01. PMID:29891061. |
abnormal methylation and altered gene expression in the developing cerebellum have been related to neurodevelopmental disorders such as autism, rett syndrome, and fragile x syndrome. |
2018-10-01 |
2023-08-13 |
Not clear |
| Julia C Shaw, Hannah K Palliser, Rebecca M Dyson, Mary J Berry, Jonathan J Hirs. Disruptions to the cerebellar GABAergic system in juvenile guinea pigs following preterm birth. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 65. 2018-09-05. PMID:29024720. |
there is increasing interest in the role of the cerebellum in these processes and the potential involvement of gabaergic pathways in neurodevelopmental disorders. |
2018-09-05 |
2023-08-13 |
Not clear |
| Isabel Hardee, Ariane Soldatos, Mariska Davids, Thierry Vilboux, Camilo Toro, Karen L David, Carlos R Ferreira, Michele Nehrebecky, Joseph Snow, Audrey Thurm, Theo Heller, Ellen F Macnamara, Meral Gunay-Aygun, Wadih M Zein, William A Gahl, May Christine V Malicda. Defective ciliogenesis in INPP5E-related Joubert syndrome. American journal of medical genetics. Part A. vol 173. issue 12. 2018-03-21. PMID:29052317. |
joubert syndrome is a neurodevelopmental disorder, characterized by malformation of the mid and hindbrain leading to the pathognomonic molar tooth appearance of the brainstem and cerebellum on axial mri. |
2018-03-21 |
2023-08-13 |
Not clear |
| Alexey V Shevelkin, Chantelle E Terrillion, Bagrat N Abazyan, Tymoteusz J Kajstura, Yan A Jouroukhin, Gay L Rudow, Juan C Troncoso, David J Linden, Mikhail V Pletniko. Expression of mutant DISC1 in Purkinje cells increases their spontaneous activity and impairs cognitive and social behaviors in mice. Neurobiology of disease. vol 103. 2018-03-02. PMID:28392471. |
as pcs express the gene disrupted-in-schizophrenia-1 (disc1), and disc1 variants have been associated with neurodevelopmental disorders, we evaluated the role of disc1 in cerebellar physiology and associated behaviors using a mouse model of inducible and selective expression of a dominant-negative, c-terminus truncated human disc1 (mutant disc1) in pcs. |
2018-03-02 |
2023-08-13 |
mouse |
| L P E Austdal, S Bjørnstad, G H Mathisen, P K Aden, I Mikkola, R E Paulsen, K E Rakkesta. Glucocorticoid Effects on Cerebellar Development in a Chicken Embryo Model: Exploring Changes in PAX6 and Metalloproteinase-9 After Exposure to Dexamethasone. Journal of neuroendocrinology. vol 28. issue 12. 2018-01-04. PMID:27791298. |
the developing cerebellum is vulnerable to effects of glucocorticoids and cerebellar dysfunction is associated with neurodevelopmental disorders (e.g. |
2018-01-04 |
2023-08-13 |
human |
| Catherine J Stoodley, Catherine Limperopoulo. Structure-function relationships in the developing cerebellum: Evidence from early-life cerebellar injury and neurodevelopmental disorders. Seminars in fetal & neonatal medicine. vol 21. issue 5. 2017-10-24. PMID:27184461. |
structure-function relationships in the developing cerebellum: evidence from early-life cerebellar injury and neurodevelopmental disorders. |
2017-10-24 |
2023-08-13 |
Not clear |
| Sara Bulgheroni, Stefano D'Arrigo, Sabrina Signorini, Marilena Briguglio, Maria Lucia Di Sabato, Manuela Casarano, Francesca Mancini, Marta Romani, Paolo Alfieri, Roberta Battini, Marina Zoppello, Gaetano Tortorella, Enrico Bertini, Vincenzo Leuzzi, Enza Maria Valente, Daria Riv. Cognitive, adaptive, and behavioral features in Joubert syndrome. American journal of medical genetics. Part A. vol 170. issue 12. 2017-10-16. PMID:27530364. |
joubert syndrome (js) is a recessive neurodevelopmental disorder characterized by a distinctive cerebellar and brainstem malformation recognizable on brain imaging, the so-called molar tooth sign. |
2017-10-16 |
2023-08-13 |
human |
| Karolina Löwgren, Rasmus Bååth, Anders Rasmussen, Henk-Jan Boele, Sebastiaan K E Koekkoek, Chris I De Zeeuw, Germund Hesslo. Performance in eyeblink conditioning is age and sex dependent. PloS one. vol 12. issue 5. 2017-09-12. PMID:28542383. |
abnormal cerebellar development may contribute to neurodevelopmental disorders such as attention deficit hyperactivity disorder (adhd), autism, fetal alcohol syndrome, dyslexia, and specific language impairment. |
2017-09-12 |
2023-08-13 |
Not clear |
| Keiko Kishimoto, Jun Nomura, Jacob Ellegood, Keita Fukumoto, Jason P Lerch, Daniel Moreno-De-Luca, Thomas Bourgeron, Kota Tamada, Toru Takum. Behavioral and neuroanatomical analyses in a genetic mouse model of 2q13 duplication. Genes to cells : devoted to molecular & cellular mechanisms. vol 22. issue 5. 2017-09-11. PMID:28370817. |
nephronophthisis-1 (nphp1) was identified as a causative gene in the minimal deletion on chromosome 2q13 for familial juvenile type 1 nephronophthisis and joubert syndrome, an autosomal recessive neurodevelopmental disorder characterized by a cerebellar and brain stem malformation, hypotonia, developmental delay, ataxia, and sometimes associated with cognitive impairment. |
2017-09-11 |
2023-08-13 |
mouse |
| Adeline Ngoh, Jose Bras, Rita Guerreiro, Esther Meyer, Amy McTague, Eleanor Dawson, Kshitij Mankad, Roxana Gunny, Peter Clayton, Philippa B Mills, Rachel Thornton, Ming Lai, Robert Forsyth, Manju A Kuria. RARS2 mutations in a sibship with infantile spasms. Epilepsia. vol 57. issue 5. 2017-05-31. PMID:27061686. |
pontocerebellar hypoplasia is a group of heterogeneous neurodevelopmental disorders characterized by reduced volume of the brainstem and cerebellum. |
2017-05-31 |
2023-08-13 |
Not clear |
| Miguel Perez-Pouchoulen, Marta Miquel, Paul Saft, Brenda Brug, Rebeca Toledo, Maria Elena Hernandez, Jorge Manz. Prenatal exposure to sodium valproate alters androgen receptor expression in the developing cerebellum in a region and age specific manner in male and female rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 53. 2017-03-27. PMID:27423376. |
this work contributes to the understanding of the cerebellar development and it might help to understand the role of the cerebellum in neurodevelopmental disorders such as autism. |
2017-03-27 |
2023-08-13 |
rat |