| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Routledge, J Hartley, J Gurling, M Ashworth-Preece, G Brown, C T Douris. In vivo characterization of the putative 5-HT1A receptor antagonist SDZ 216,525 using two models of somatodendritic 5-HT1A receptor function. Neuropharmacology. vol 33. issue 3-4. 1994-12-30. PMID:7984274. |
however, the failure of the 5-ht1a receptor antagonist (rs)-way100135 to block the sdz 216,525 responses suggests that sdz 216,525 decreases 5-ht release and increases food intake by a mechanism other than 5-ht1a receptor agonism. |
1994-12-30 |
2023-08-12 |
rat |
| M Jhanwar-Uniyal, B Moorjani, A H Kah. Indications of pre- and post-synaptic 5-HT1A receptor interactions in feeding behavior and neuroendocrine regulation. Brain research. vol 646. issue 2. 1994-09-23. PMID:8069671. |
indications of pre- and post-synaptic 5-ht1a receptor interactions in feeding behavior and neuroendocrine regulation. |
1994-09-23 |
2023-08-12 |
rat |
| M Jhanwar-Uniyal, B Moorjani, A H Kah. Indications of pre- and post-synaptic 5-HT1A receptor interactions in feeding behavior and neuroendocrine regulation. Brain research. vol 646. issue 2. 1994-09-23. PMID:8069671. |
this bipartite study uses behavioral and biochemical means to explore the involvement of both pre- and post-synaptic 5-ht1a receptors in the control of food intake and neuroendocrine regulation. |
1994-09-23 |
2023-08-12 |
rat |
| I S Ebenezer, R Tit. Sex difference in the feeding responses of non-deprived rats to the 5-HT1A agonists 8-OH-DPAT and gepirone. Methods and findings in experimental and clinical pharmacology. vol 16. issue 2. 1994-07-21. PMID:8007747. |
sex difference in the feeding responses of non-deprived rats to the 5-ht1a agonists 8-oh-dpat and gepirone. |
1994-07-21 |
2023-08-12 |
rat |
| I S Ebenezer, R Tit. Sex difference in the feeding responses of non-deprived rats to the 5-HT1A agonists 8-OH-DPAT and gepirone. Methods and findings in experimental and clinical pharmacology. vol 16. issue 2. 1994-07-21. PMID:8007747. |
the aim of this study was to determine whether there was any difference in the feeding responses of male and female rats to the 5-ht1a agonists 8-hydroxy-2(di-n-propylamino)tetralin (8-oh-dpat) and gepirone. |
1994-07-21 |
2023-08-12 |
rat |
| H Koike, H Saito, N Matsuk. 5-HT1A receptor-mediated inhibition of N-type calcium current in acutely isolated ventromedial hypothalamic neuronal cells. Neuroscience research. vol 19. issue 2. 1994-07-20. PMID:8008244. |
these results indicate that 5-ht suppresses ca2+ entry through n-type channels in the vmh neurons via the 5-ht1a receptor and that the stimulating effect of 8-oh-dpat on feeding behavior may be mediated by the blocking of ca2+ entry through n-type channels. |
1994-07-20 |
2023-08-12 |
Not clear |
| J E Hartley, A Fletche. The effects of WAY-100135 and 8-hydroxy-2-(di-n-propylamino)tetralin on feeding in the rat. European journal of pharmacology. vol 252. issue 3. 1994-05-20. PMID:8162954. |
these data provide the first demonstration of the antagonism, by a selective 5-ht1a receptor antagonist, of 8-oh-dpat-induced feeding; an effect mediated via the somatodendritic 5-ht1a autoreceptor. |
1994-05-20 |
2023-08-12 |
rat |
| J E Hartley, A Fletche. The effects of WAY-100135 and 8-hydroxy-2-(di-n-propylamino)tetralin on feeding in the rat. European journal of pharmacology. vol 252. issue 3. 1994-05-20. PMID:8162954. |
these results also suggest that 5-ht1a receptor antagonists may have no intrinsic effect on food intake or feeding behaviour. |
1994-05-20 |
2023-08-12 |
rat |
| P J Currie, D V Coscin. Diurnal variations in the feeding response to 8-OH-DPAT injected into the dorsal or median raphe. Neuroreport. vol 4. issue 9. 1993-11-29. PMID:8219034. |
to determine the impact on food intake of the 5-ht1a agonist, 8-oh-dpat, administered at various times throughout the nocturnal cycle, rats were implanted with cannulae in either the dorsal or median raphe nuclei and injected with saline or 8-oh-dpat (0.4, 0.8 or 1.6 nmol) immediately following dark onset, or during the mid or late dark periods. |
1993-11-29 |
2023-08-12 |
rat |
| L H Pan, F Gilber. Identification of different mechanisms of action for increases of food intake and plasma ACTH concentration following 5-HT1a receptor subtype activation in rat brain. Psychoneuroendocrinology. vol 18. issue 2. 1993-06-16. PMID:8388111. |
identification of different mechanisms of action for increases of food intake and plasma acth concentration following 5-ht1a receptor subtype activation in rat brain. |
1993-06-16 |
2023-08-12 |
rat |
| L H Pan, F Gilber. Identification of different mechanisms of action for increases of food intake and plasma ACTH concentration following 5-HT1a receptor subtype activation in rat brain. Psychoneuroendocrinology. vol 18. issue 2. 1993-06-16. PMID:8388111. |
both food intake and pituitary acth release respond to activation of serotonergic 5-ht1a receptors. |
1993-06-16 |
2023-08-12 |
rat |
| L H Pan, F Gilber. Identification of different mechanisms of action for increases of food intake and plasma ACTH concentration following 5-HT1a receptor subtype activation in rat brain. Psychoneuroendocrinology. vol 18. issue 2. 1993-06-16. PMID:8388111. |
this suggests that, among its various possible mechanisms of action, 8-oh-dpat induces an increase of food intake in rats by activating presynaptic 5-ht1a autoreceptors in the raphé nuclei, where most serotonergic fibers originate, while its effect on plasma acth concentration occurs through activation of postsynaptic 5-ht1a receptors in the pvn, where some serotonergic fibers terminate. |
1993-06-16 |
2023-08-12 |
rat |
| I S Ebeneze. Effects of the 5-HT1A agonist 8-OH-DPAT on food intake in food-deprived rats. Neuroreport. vol 3. issue 11. 1993-02-16. PMID:1482760. |
effects of the 5-ht1a agonist 8-oh-dpat on food intake in food-deprived rats. |
1993-02-16 |
2023-08-11 |
rat |
| D V Coscina, E C de Roo. Effects of intracisternal vs. intrahypothalamic 5,7-DHT on feeding elicited by hypothalamic infusion of NE. Brain research. vol 597. issue 2. 1993-02-03. PMID:1473002. |
a functional index of 5-ht terminal damage was also implied by the impaired short-term feeding responses ic-5,7-dht rats showed to the systemic administration of the 5-ht1a agonist, 8-hydroxy-2-(di-n-propylamino) tetralin (8-oh-dpat) when tested between 3 and 4 weeks after ic treatment. |
1993-02-03 |
2023-08-11 |
rat |
| H C Jackson, D J Nut. Are 5-HT receptors or beta-adrenoceptors involved in idazoxan-induced food and water intake? Neuropharmacology. vol 31. issue 11. 1993-02-02. PMID:1361965. |
also significantly inhibited the food intake, induced by the 5-ht1a agonist 8-oh-dpat (0.25 mg/kg, i.p.). |
1993-02-02 |
2023-08-11 |
rat |
| B Poeschla, J Gibbs, K J Simansky, G P Smit. The 5-HT1A agonist 8-OH-DPAT attenuates the satiating action of cholecystokinin. Pharmacology, biochemistry, and behavior. vol 42. issue 3. 1992-11-18. PMID:1409788. |
to investigate the dependence of the satiating action of cholecystokinin (cck) on serotonergic action at central 5-ht receptors, we examined the effect of systemic pretreatment with 8-oh-dpat (a 5-ht1a agonist that decreases central 5-ht synthesis and release via an action at somatodendritic autoreceptors in the brainstem raphe) on the suppression of food intake induced by systemic administration of cholecystokinin octapeptide (ckk-8). |
1992-11-18 |
2023-08-11 |
Not clear |
| A R Williams, C T Douris. Effects of the putative 5-HT1A receptor antagonist NAN-190 on free feeding and on feeding induced by the 5-HT1A receptor agonist 8-OH-DPAT in the rat. European journal of pharmacology. vol 219. issue 1. 1992-11-06. PMID:1397037. |
effects of the putative 5-ht1a receptor antagonist nan-190 on free feeding and on feeding induced by the 5-ht1a receptor agonist 8-oh-dpat in the rat. |
1992-11-06 |
2023-08-11 |
rat |
| A R Williams, C T Douris. Effects of the putative 5-HT1A receptor antagonist NAN-190 on free feeding and on feeding induced by the 5-HT1A receptor agonist 8-OH-DPAT in the rat. European journal of pharmacology. vol 219. issue 1. 1992-11-06. PMID:1397037. |
in interaction studies, nan-190 (0.1 and 10 mg/kg) failed to block the feeding response induced by the prototypical 5-ht1a receptor agonist 8-oh-dpat (0.0625 and 1.0 mg/kg) and indeed, appeared to have an additive effect with 8-oh-dpat on consummatory behaviour. |
1992-11-06 |
2023-08-11 |
rat |
| S M Korte, G A Bouws, J M Koolhaas, B Bohu. Neuroendocrine and behavioral responses during conditioned active and passive behavior in the defensive burying/probe avoidance paradigm: effects of ipsapirone. Physiology & behavior. vol 52. issue 2. 1992-10-15. PMID:1355919. |
the 5-ht1a agonist ipsapirone, with anxiolytic properties, dose-dependently (0.5 and 2.5 mg/kg, iv) reduced defensive burying behavior and increased the amount of time spent on feeding behavior in the presence of bedding material. |
1992-10-15 |
2023-08-11 |
rat |
| I S Ebeneze. Effects of the 5HT1A agonist, 8-OH-DPAT, on operant food intake in non-deprived rats. Neuroreport. vol 3. issue 1. 1992-07-29. PMID:1535232. |
effects of the 5ht1a agonist, 8-oh-dpat, on operant food intake in non-deprived rats. |
1992-07-29 |
2023-08-11 |
rat |