| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shuo Zhao, Jinpeng Zhang, Yufeng Chen, Xinyuan Cui, Haiqing Liu, Ying Yan, Yuexiang Sun, Yongxiu Qi, Yuanyuan Li. The comprehensive mechanism underlying Schisandra polysaccharide in AD-like symptoms of Aβ25-35-induced rats based on hippocampal metabolomics and serum lipidomics techniques. Journal of pharmaceutical and biomedical analysis. vol 236. 2023-09-16. PMID:37716276. |
the pharmacodynamic results revealed that scp significantly improved the spatial learning and long-term memory function and the morphology of neurons in the hippocampal ca1 region, alleviated inflammatory damage and oxidative stress, inhibited the activation of microglia and astrocytes, and increased the proportion of mature neurons of ad-like symptoms of aβ25-35-induced rats. |
2023-09-16 |
2023-10-07 |
rat |
| Miquel Martin, Matteo M Pusceddu, Joan Teichenné, Teresa Negra, Alan Connolly, Xavier Escoté, Helena Torrell Galceran, Adrià Cereto Massagué, Iris Samarra Mestre, Antoni Del Pino Rius, Jordi Romero-Gimenez, Cristina Egea, Juan Maria Alcaide-Hidalgo, Josep Maria Del Ba. Preventive Treatment with Astaxanthin Microencapsulated with Spirulina Powder, Administered in a Dose Range Equivalent to Human Consumption, Prevents LPS-Induced Cognitive Impairment in Rats. Nutrients. vol 15. issue 13. 2023-07-14. PMID:37447181. |
our results demonstrate that lps modified long-term memory in the mwm and increased microglia activation in the hippocampus and prefrontal cortex. |
2023-07-14 |
2023-08-14 |
human |
| Xiaoming Zhang, Laura Kracht, Antonio M Lerario, Marissa L Dubbelaar, Nieske Brouwer, Evelyn M Wesseling, Erik W G M Boddeke, Bart J L Eggen, Susanne M Kooistr. Epigenetic regulation of innate immune memory in microglia. Journal of neuroinflammation. vol 19. issue 1. 2022-05-15. PMID:35568856. |
a consequence of their relative slow turnover is that microglia can serve as a long-term memory for inflammatory or neurodegenerative events. |
2022-05-15 |
2023-08-13 |
Not clear |
| Henrique C Campos, Deidiane Elisa Ribeiro, Debora Hashiguchi, Deborah Y Hukuda, Christiane Gimenes, Simone A A Romariz, Qing Ye, Yong Tang, Henning Ulrich, Beatriz Monteiro Long. Distinct Effects of the Hippocampal Transplantation of Neural and Mesenchymal Stem Cells in a Transgenic Model of Alzheimer's Disease. Stem cell reviews and reports. 2022-01-08. PMID:34997526. |
therefore, the present study aimed to investigate whether transplantation of nsc or msc into the hippocampus of app/ps1 mice reverses ad-induced pathological alterations, evaluated by the locomotor activity (open field test), short- and long-term memory (object recognition) tests, Αβ plaques (6-e10), microglia distribution (iba-1), m1 (inos) and m2 (arg-1) microglial phenotype frequencies. |
2022-01-08 |
2023-08-13 |
mouse |
| Gaia Scabia, Giovanna Testa, Manuela Scali, Serena Del Turco, Genni Desiato, Nicoletta Berardi, Alessandro Sale, Michela Matteoli, Lamberto Maffei, Margherita Maffei, Marco Mainard. Reduced ccl11/eotaxin mediates the beneficial effects of environmental stimulation on the aged hippocampus. Brain, behavior, and immunity. vol 98. 2021-12-09. PMID:34418501. |
interfering, in mice, with the ccl11 decrease induced by ee ablated the beneficial effects on long-term memory retention, hippocampal neurogenesis, activation of local microglia and of ribosomal protein s6. |
2021-12-09 |
2023-08-13 |
mouse |
| R L Moretti, E N Dias, S G Kiel, M C M Augusto, P S Rodrigues, A C S Sampaio, L S Medeiros, M F M Martins, I B Suffredini, C V Cardoso, E F Bonda. Behavioral and morphological effects of resveratrol and curcumin in rats submitted to doxorubicin-induced cognitive impairment. Research in veterinary science. vol 140. 2021-10-15. PMID:34536813. |
dox-injected rats presented short-term and long-term memory impairments as seen in the nort at 3 and 24 h after habituation and increased gfap and iba1 expression, respectively, in astrocytes and microglia of the frontal cortex, hypothalamus and hippocampus. |
2021-10-15 |
2023-08-13 |
rat |
| Sandra Bonfante, Larissa Joaquim, Maria Eduarda Fileti, Amanda Della Giustina, Mariana Pereira de Souza Goldim, Lucinéia Gainski Danielski, Evandro Cittadin, Raquel Jaconi De Carli, Bianca Xavier de Farias, Nicole Alessandra Engel, Naiana da Rosa, Jucélia Jeremias Fortunato, Vijayasree Giridharan, Giselli Scaini, Gislaine Tezza Rezin, Jaqueline Generoso, Rafael Mariano de Bitencourt, Silvia Terra, Tatiana Barichello, Fabricia Petronilh. Stanniocalcin 1 Inhibits the Inflammatory Response in Microglia and Protects Against Sepsis-Associated Encephalopathy. Neurotoxicity research. vol 39. issue 2. 2021-03-10. PMID:33025358. |
here, we demonstrated a protective role of stc-1 on inflammatory responses in vitro, in activated microglia stimulated with lps, and on neuroinflammation, oxidative stress, and mitochondrial function in the hippocampus of rats subjected to an animal model of sepsis by cecal ligation and puncture (clp), as well the consequences on long-term memory. |
2021-03-10 |
2023-08-13 |
human |
| Susanna Ros. The final frontier: Transient microglia reduction after cosmic radiation exposure mitigates cognitive impairments and modulates phagocytic activity. Brain circulation. vol 4. issue 3. 2020-10-01. PMID:30450416. |
brief depletion of microglia after irradiation mitigated the development of any long-term memory deficits, comparable to healthy animals. |
2020-10-01 |
2023-08-13 |
Not clear |
| Karen Krukowski, Xi Feng, Maria Serena Paladini, Austin Chou, Kristen Sacramento, Katherine Grue, Lara-Kirstie Riparip, Tamako Jones, Mary Campbell-Beachler, Gregory Nelson, Susanna Ros. Temporary microglia-depletion after cosmic radiation modifies phagocytic activity and prevents cognitive deficits. Scientific reports. vol 8. issue 1. 2019-10-04. PMID:29777152. |
we find that temporary microglia depletion, one week after cosmic radiation, prevents the development of long-term memory deficits. |
2019-10-04 |
2023-08-13 |
Not clear |
| Zhuangzhuang Chen, Di Zhong, Guozhong L. The role of microglia in viral encephalitis: a review. Journal of neuroinflammation. vol 16. issue 1. 2019-08-05. PMID:30967139. |
on the other hand, microglia mediate presynaptic membrane damage in the hippocampus through complement, resulting in long-term memory impairment and cognitive dysfunction in patients with encephalitis. |
2019-08-05 |
2023-08-13 |
Not clear |
| Alex P Salam, Carmine M Pariante, Patricia Zunszai. Innate Immune Memory: Implications for Microglial Function and Neuroprogression. Modern trends in pharmacopsychiatry. vol 31. 2019-05-06. PMID:28738336. |
in turn, we hypothesize that microglia, the resident innate immune cells of the brain, are also capable of retaining long-term memory of infectious and noninfectious insults, including stress. |
2019-05-06 |
2023-08-13 |
Not clear |
| Hallel C Paraiso, Ping-Chang Kuo, Eric T Curfman, Haley J Moon, Robert D Sweazey, Jui-Hung Yen, Fen-Lei Chang, I-Chen Y. Dimethyl fumarate attenuates reactive microglia and long-term memory deficits following systemic immune challenge. Journal of neuroinflammation. vol 15. issue 1. 2019-04-08. PMID:29598822. |
dimethyl fumarate attenuates reactive microglia and long-term memory deficits following systemic immune challenge. |
2019-04-08 |
2023-08-13 |
Not clear |
| Abbas Aliaghaei, Hadi Digaleh, Fariba Khodagholi, Abolhassan Ahmadian. Encapsulated Choroid Plexus Epithelial Cells Actively Protect Against Intrahippocampal Aβ-induced Long-Term Memory Dysfunction; Upregulation of Effective Neurogenesis with the Abrogated Apoptosis and Neuroinflammation. Journal of molecular neuroscience : MN. vol 56. issue 3. 2016-03-24. PMID:25634726. |
our data suggest that transplantation of encapsulated cpecs resulted in a significant decrease in apoptosis, reduced migration microglia, diminished gliosis, increased neurogenesis, and improved long-term memory as well as upregulated antioxidant activity. |
2016-03-24 |
2023-08-13 |
rat |