| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V Lessman. Neurotrophin-dependent modulation of glutamatergic synaptic transmission in the mammalian CNS. General pharmacology. vol 31. issue 5. 1998-12-23. PMID:9809461. |
in addition, long-term potentiation (a potential cellular correlate for learning and memory formation in mammals) in the rodent hippocampus depends on endogenous supply of neurons with bdnf. |
1998-12-23 |
2023-08-12 |
Not clear |
| J Kornhuber, J Wiltfang, J Kornbube. The role of glutamate in dementia. Journal of neural transmission. Supplementum. vol 53. 1998-11-12. PMID:9700664. |
when following the antagonist strategy, the goal is to provide neuroprotective effects via glutamate receptor antagonisms without inhibiting the physiological transmission that is required for learning and memory formation. |
1998-11-12 |
2023-08-12 |
Not clear |
| L B Zou, K Yamada, T Tanaka, T Kameyama, T Nabeshim. Nitric oxide synthase inhibitors impair reference memory formation in a radial arm maze task in rats. Neuropharmacology. vol 37. issue 3. 1998-10-02. PMID:9681930. |
we investigated the role of nitric oxide (no) in learning and memory formation in a radial maze test, by using the no synthase (nos) inhibitors, ng-nitro-l-arginine methyl ester (l-name) and 7-nitroindazole (7-ni), and an no precursor, l-arginine. |
1998-10-02 |
2023-08-12 |
rat |
| M J Thomas, A M Watabe, T D Moody, M Makhinson, T J O'Del. Postsynaptic complex spike bursting enables the induction of LTP by theta frequency synaptic stimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 18. 1998-10-02. PMID:9736635. |
our results suggest that complex spike bursting may have an important role in synaptic processes involved in learning and memory formation, perhaps by producing a highly sensitive postsynaptic state during which even low frequencies of presynaptic activity can induce ltp. |
1998-10-02 |
2023-08-12 |
Not clear |
| Z Nusser, N Hájos, P Somogyi, I Mod. Increased number of synaptic GABA(A) receptors underlies potentiation at hippocampal inhibitory synapses. Nature. vol 395. issue 6698. 1998-10-01. PMID:9744275. |
changes in synaptic efficacy are essential for neuronal development, learning and memory formation and for pathological states of neuronal excitability, including temporal-lobe epilepsy. |
1998-10-01 |
2023-08-12 |
Not clear |
| A H Gazzaley, M M Thakker, P R Hof, J H Morriso. Preserved number of entorhinal cortex layer II neurons in aged macaque monkeys. Neurobiology of aging. vol 18. issue 5. 1997-12-30. PMID:9390783. |
the perforant path, which consists of the projection from the layer ii neurons of the entorhinal cortex to the outer molecular layer of the dentate gyrus, is a critical circuit involved in learning and memory formation. |
1997-12-30 |
2023-08-12 |
monkey |
| T M Brotz, B Bochenek, K Aronstein, R H Ffrench-Constant, A Bors. gamma-Aminobutyric acid receptor distribution in the mushroom bodies of a fly (Calliphora erythrocephala): a functional subdivision of Kenyon cells? The Journal of comparative neurology. vol 383. issue 1. 1997-08-01. PMID:9184984. |
gabaergic inhibition, therefore, may play a substantial role in the process of learning and memory formation in the insect mushroom bodies. |
1997-08-01 |
2023-08-12 |
drosophila_melanogaster |
| K T Ng, B S O'Dowd, N S Rickard, S R Robinson, M E Gibbs, C Rainey, W Q Zhao, G L Sedman, L Hert. Complex roles of glutamate in the Gibbs-Ng model of one-trial aversive learning in the new-born chick. Neuroscience and biobehavioral reviews. vol 21. issue 1. 1997-04-11. PMID:8994208. |
glutamate is the most widespread excitatory transmitter in the cns and is probably involved in ltp, a neural phenomenon which may be associated with learning and memory formation. |
1997-04-11 |
2023-08-12 |
chicken |
| H Scheich, H Stark, W Zuschratter, F W Ohl, C E Simoni. Some functions of primary auditory cortex in learning and memory formation. Advances in neurology. vol 73. 1997-03-19. PMID:8959214. |
some functions of primary auditory cortex in learning and memory formation. |
1997-03-19 |
2023-08-12 |
Not clear |
| C Hölscher, L McGlinchey, M J Rowa. L-AP4 (L-(+)-2-amino-4-phosphonobutyric acid) induced impairment of spatial learning in the rat is antagonized by MAP4 ((S)-2-amino-2-methyl-4-phosphonobutanoic acid). Behavioural brain research. vol 81. issue 1-2. 1997-03-13. PMID:8950003. |
we conclude that l-ap4 sensitive metabotropic glutamate receptors play a selective role in learning and memory formation of the rat. |
1997-03-13 |
2023-08-12 |
rat |
| K Yamada, M Hiramatsu, Y Noda, T Mamiya, M Murai, T Kameyama, Y Komori, T Nikai, H Sugihara, T Nabeshim. Role of nitric oxide and cyclic GMP in the dizocilpine-induced impairment of spontaneous alternation behavior in mice. Neuroscience. vol 74. issue 2. 1997-01-06. PMID:8865189. |
the inhibition of nitric oxide production, as well as the blockade of n-methyl-d-aspartate receptors, has been reported to prevent the induction of hippocampal long-term potentiation and learning and memory formation in vivo, although the effects of inhibitors of nitric oxide synthase are still controversial. |
1997-01-06 |
2023-08-12 |
mouse |
| S Maren, M Baudr. Properties and mechanisms of long-term synaptic plasticity in the mammalian brain: relationships to learning and memory. Neurobiology of learning and memory. vol 63. issue 1. 1995-10-10. PMID:7663875. |
long-term potentiation (ltp) in the hippocampus and long-term depression (ltd) in the cerebellum are two forms of long-lasting synaptic plasticity that currently serve as our primary experimental models of learning and memory formation in mammals. |
1995-10-10 |
2023-08-12 |
Not clear |
| S Mitake, K Ojika, E Katada, Y Otsuka, N Matsukawa, O Fujimor. Accumulation of hippocampal cholinergic neurostimulating peptide (HCNP)-related components in Hirano bodies. Neuropathology and applied neurobiology. vol 21. issue 1. 1995-07-05. PMID:7770119. |
the present findings indicate that hcnp-related components accumulate in hirano bodies, suggesting that patients who bear these inclusions may have a disturbance of the septo-hippocampal cholinergic system, considered to be of importance for learning and memory formation. |
1995-07-05 |
2023-08-12 |
human |
| A Bartholomä, K A Nav. NEX-1: a novel brain-specific helix-loop-helix protein with autoregulation and sustained expression in mature cortical neurons. Mechanisms of development. vol 48. issue 3. 1995-04-27. PMID:7545978. |
high levels of its mrna are sustained in mature pyramidal neurons of the hippocampus, cerebellum and several neocortical areas previously associated with learning and memory formation. |
1995-04-27 |
2023-08-12 |
mouse |
| W Tischmeyer, R Grimm, H Schicknick, W Brysch, K H Schlingensiepe. Sequence-specific impairment of learning by c-jun antisense oligonucleotides. Neuroreport. vol 5. issue 12. 1994-12-23. PMID:7948848. |
supposing that early gene expression is functionally significant for plastic changes in the brain, we used antisense phosphorothioate oligodeoxynucleotides (s-odn) in vivo to study effects of specific inhibition of c-jun and jun b gene expression on learning and memory formation in rat brain. |
1994-12-23 |
2023-08-12 |
rat |
| J W Lazarewicz, E Salinska, J T Wroblewsk. NMDA receptor-mediated arachidonic acid release in neurons: role in signal transduction and pathological aspects. Advances in experimental medicine and biology. vol 318. 1992-08-26. PMID:1386178. |
the n-methyl-d-aspartate (nmda)-sensitive subtype of glutamate receptor, which gates ca(2+)-permeable ion channels, is known for its role in learning and memory formation, in the induction of long-term potentiation, and also in seizure activity and neurotoxicity. |
1992-08-26 |
2023-08-11 |
rat |
| N Popov, S Schulzeck, D Nüss, A U Vopel, C Jendrny, H Struy, H Matthie. Alterations in calmodulin content of rat brain areas after chronic application of haloperidol and amphetamine. Biomedica biochimica acta. vol 47. issue 4-5. 1989-04-25. PMID:3240294. |
the hippocampus, the region poor in dopamine while playing an essential role in learning and memory formation processes, revealed similar patterns after both modes of treatment. |
1989-04-25 |
2023-08-11 |
rat |
| W D Blaker, S D Goodwi. Biochemical and behavioral effects of intrahippocampal AF64A in rats. Pharmacology, biochemistry, and behavior. vol 28. issue 2. 1988-01-13. PMID:3685051. |
we conclude that even relatively minor, localized, cholinergic deficits confined to the hippocampus can produce significant learning and memory impairments in situations where intermediate or long term memory formation is required. |
1988-01-13 |
2023-08-11 |
rat |