| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nadine Curdt, Franziska W Schmitt, Caroline Bouter, Trendelina Iseni, Hanna C Weile, Berfin Altunok, Nicola Beindorff, Thomas A Bayer, Matthew B Cooke, Yvonne Boute. Search strategy analysis of Tg4-42 Alzheimer Mice in the Morris Water Maze reveals early spatial navigation deficits. Scientific reports. vol 12. issue 1. 2022-04-01. PMID:35361814. |
the spatial navigation impairments in young tg4-42 mice are well in line with the hypometabolism and synaptic deficits in the hippocampus. |
2022-04-01 |
2023-08-13 |
mouse |
| Qiliang He, Jon Starnes, Thackery I Brow. Environmental overlap influences goal-oriented coding of spatial sequences differently along the long-axis of hippocampus. Hippocampus. 2022-03-21. PMID:35312204. |
together, our findings provide insight into the influences of contextual overlap on the long-axis of the hippocampus and a broader memory and planning network that we have long-associated with such navigation tasks. |
2022-03-21 |
2023-08-13 |
human |
| Xinzhu Y. Hippocampal astrocytes represent navigation space. PLoS biology. vol 20. issue 3. 2022-03-08. PMID:35259150. |
hippocampal astrocytes represent navigation space. |
2022-03-08 |
2023-08-13 |
Not clear |
| Lorena Morales, Alba González-Alonso, Ester Desfilis, Loreta Medin. Precise Mapping of Otp Expressing Cells Across Different Pallial Regions Throughout Ontogenesis Using Otp-Specific Reporter Transgenic Mice. Frontiers in neural circuits. vol 16. 2022-03-07. PMID:35250495. |
regarding otp cells in the parahippocampal lobe, they seem to be projection neurons and may regulate hippocampal function during spatial navigation and memory formation. |
2022-03-07 |
2023-08-13 |
mouse |
| Lu Zhang, Stephanie M Prince, Abigail L Paulson, Annabelle C Singe. Goal discrimination in hippocampal nonplace cells when place information is ambiguous. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 11. 2022-03-07. PMID:35254897. |
significancegoal-directed spatial navigation has been found to rely on hippocampal neurons that are spatially modulated. |
2022-03-07 |
2023-08-13 |
mouse |
| Edmund T Rolls, Gustavo Deco, Chu-Chung Huang, Jianfeng Fen. The human orbitofrontal cortex, vmPFC, and anterior cingulate cortex effective connectome: emotion, memory, and action. Cerebral cortex (New York, N.Y. : 1991). 2022-03-02. PMID:35233615. |
the orbitofrontal cortex has connectivity to the pregenual anterior and posterior cingulate cortex and hippocampal system and provides for rewards to be used in memory and navigation to goals. |
2022-03-02 |
2023-08-13 |
human |
| Zilu Liu, Qingyun Wang, Fang Ha. Synaptic Role in Facilitating Synchronous Theta Oscillations in a Hybrid Hippocampal Neuronal Network. Frontiers in computational neuroscience. vol 16. 2022-02-21. PMID:35185504. |
theta rhythms (4-12 hz) in the hippocampus are thought to be associated with cognitive functions such as memory processing and spatial navigation. |
2022-02-21 |
2023-08-13 |
Not clear |
| Anup Das, Vinod Meno. Replicable patterns of causal information flow between hippocampus and prefrontal cortex during spatial navigation and spatial-verbal memory formation. Cerebral cortex (New York, N.Y. : 1991). 2022-02-09. PMID:35136979. |
replicable patterns of causal information flow between hippocampus and prefrontal cortex during spatial navigation and spatial-verbal memory formation. |
2022-02-09 |
2023-08-13 |
human |
| Anup Das, Vinod Meno. Replicable patterns of causal information flow between hippocampus and prefrontal cortex during spatial navigation and spatial-verbal memory formation. Cerebral cortex (New York, N.Y. : 1991). 2022-02-09. PMID:35136979. |
interactions between the hippocampus and prefrontal cortex (pfc) play an essential role in both human spatial navigation and episodic memory, but the underlying causal flow of information between these regions across task domains is poorly understood. |
2022-02-09 |
2023-08-13 |
human |
| Gillian Coughlan, Ryan Larsen, Min Kim, David White, Rachel Gillings, Michael Irvine, Andrew Scholey, Neal Cohen, Cristina Legido-Quigley, Michael Hornberger, Anne-Maire Minihan. APOE ε4 alters docosahexaenoic acid's influence on preclinical markers of Alzheimer disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35108870. |
this is despite the fact that spatial navigation deficits are a new cognitive fingerprint for symptomatic and asymptomatic ad, and that spatial navigation crucially relies on hippocampal and the entorhinal cortex integrity. |
2022-02-03 |
2023-08-13 |
human |
| Gillian Coughlan, Ryan Larsen, Min Kim, David White, Rachel Gillings, Michael Irvine, Andrew Scholey, Neal Cohen, Cristina Legido-Quigley, Michael Hornberger, Anne-Maire Minihan. APOE ε4 alters docosahexaenoic acid's influence on preclinical markers of Alzheimer disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35108870. |
thus, we investigated the relationship between dha levels and the major structural and cognitive markers of preclinical ad, namely hippocampal volume, entorhinal volume, and spatial navigation ability, across two independent non-demented populations. |
2022-02-03 |
2023-08-13 |
human |
| Lu Zhang, Ping Chen, Matthew Schafer, Senning Zheng, Lixiang Chen, Shuai Wang, Qunjun Liang, Qing Qi, Yichen Zhang, Ruiwang Huan. A specific brain network for a social map in the human brain. Scientific reports. vol 12. issue 1. 2022-02-03. PMID:35110581. |
our findings suggest a brain network for social navigation in multiple abstract, social dimensions that includes the hippocampus, precuneus, dlpfc, and insula. |
2022-02-03 |
2023-08-13 |
human |
| Chao Yu, Cynthia F Mos. Natural acoustic stimuli evoke selective responses in the hippocampus of passive listening bats. Hippocampus. 2022-01-27. PMID:35085416. |
a growing body of research details spatial representation in bat hippocampus, and experiments have yet to explore hippocampal neuron responses to sonar signals in animals that rely on echolocation for spatial navigation. |
2022-01-27 |
2023-08-13 |
Not clear |
| Sebnem N Tuncdemir, Andres D Grosmark, Gergely F Turi, Amei Shank, John C Bowler, Gokhan Ordek, Attila Losonczy, Rene Hen, Clay O Lacefiel. Parallel processing of sensory cue and spatial information in the dentate gyrus. Cell reports. vol 38. issue 3. 2022-01-19. PMID:35045280. |
the dentate gyrus (dg) is the first stage of the hippocampal circuit where self-motion ("where") and sensory cue information ("what") are integrated, but it remains unknown how dg neurons encode this information during cognitive map formation. |
2022-01-19 |
2023-08-13 |
mouse |
| Sebi V Rolotti, Mohsin S Ahmed, Miklos Szoboszlay, Tristan Geiller, Adrian Negrean, Heike Blockus, Kevin C Gonzalez, Fraser T Sparks, Ana Sofia Solis Canales, Anna L Tuttman, Darcy S Peterka, Boris V Zemelman, Franck Polleux, Attila Losoncz. Local feedback inhibition tightly controls rapid formation of hippocampal place fields. Neuron. 2022-01-06. PMID:34990571. |
hippocampal place cells underlie spatial navigation and memory. |
2022-01-06 |
2023-08-13 |
mouse |
| Lucia F Jacob. How the evolution of air breathing shaped hippocampal function. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 377. issue 1844. 2021-12-27. PMID:34957846. |
hence the independent evolution of echolocation in bats and toothed whales was accompanied by a loss of hippocampal structure (whales) and an absence of hippocampal theta oscillations during navigation (bats). |
2021-12-27 |
2023-08-13 |
mouse |
| Shinya Ohara, Rintaro Yoshino, Kei Kimura, Taichi Kawamura, Soshi Tanabe, Andi Zheng, Shinya Nakamura, Ken-Ichi Inoue, Masahiko Takada, Ken-Ichiro Tsutsui, Menno P Witte. Laminar Organization of the Entorhinal Cortex in Macaque Monkeys Based on Cell-Type-Specific Markers and Connectivity. Frontiers in neural circuits. vol 15. 2021-12-24. PMID:34949991. |
the entorhinal cortex (ec) is a major gateway between the hippocampus and telencephalic structures, and plays a critical role in memory and navigation. |
2021-12-24 |
2023-08-13 |
monkey |
| Amy Shepherd, Tracy Zhang, Lucas B Hoffmann, Ariel M Zeleznikow-Johnston, Leonid Churilov, Anthony J Hannan, Emma L Burrow. A Preclinical Model of Computerized Cognitive Training: Touchscreen Cognitive Testing Enhances Cognition and Hippocampal Cellular Plasticity in Wildtype and Alzheimer's Disease Mice. Frontiers in behavioral neuroscience. vol 15. 2021-12-23. PMID:34938165. |
this is the first study to show increased numbers of proliferating cells and immature neurons in the hippocampus following touchscreen testing, and that touchscreen training can improve cognitive performance in maze-based spatial navigation tasks. |
2021-12-23 |
2023-08-13 |
mouse |
| Wenbo Tang, Shantanu P Jadha. Multiple-Timescale Representations of Space: Linking Memory to Navigation. Annual review of neuroscience. 2021-12-22. PMID:34936810. |
we further discuss recent work suggesting the prevalence of these sequences beyond hippocampus and propose that these multiple-timescale mechanisms may represent a general algorithm for organizing cell assemblies, potentially unifying the dual roles of the spatial representation system in memory and navigation. |
2021-12-22 |
2023-08-13 |
Not clear |
| O M Femi-Akinlosotu, M T Shokunbi, F E Olopade, P Igbon. Deficits of Learning and Spatial Memory are Associated with Increased Pyknosis of Pyramidal Neurons of the Hippocampus of Adult Rats with Chronic Hydrocephalus. West African journal of medicine. vol Vol. 38. issue 11. 2021-12-17. PMID:34919360. |
the hippocampus is the brain's centre for the consolidation of short-term and spatial memory that enables navigation. |
2021-12-17 |
2023-08-13 |
rat |