| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sanne Ten Oever, Alexander T Sack, Carina R Oehrn, Nikolai Axmache. An engram of intentionally forgotten information. Nature communications. vol 12. issue 1. 2021-11-22. PMID:34750407. |
additional analyses revealed selective modification of item-specific patterns of connectivity and top-down information flow from dorsolateral prefrontal cortex to lateral temporal cortex in memory traces of intentionally forgotten items. |
2021-11-22 |
2023-08-13 |
Not clear |
| Miao Li, David Cabrera-Garcia, Michael C Salling, Edmund Au, Guang Yang, Neil L Harriso. Alcohol reduces the activity of somatostatin interneurons in the mouse prefrontal cortex: A neural basis for its disinhibitory effect? Neuropharmacology. vol 188. 2021-11-19. PMID:33636191. |
the prefrontal cortex (pfc) is involved in executive ("top-down") control of behavior and its function is especially susceptible to the effects of alcohol, leading to behavioral disinhibition that is associated with alterations in decision making, response inhibition, social anxiety and working memory. |
2021-11-19 |
2023-08-13 |
mouse |
| Olga R Dobrushina, Galina A Arina, Larisa A Dobrynina, Evgenia S Novikova, Mariia V Gubanova, Anastasia V Belopasova, Viktoriia P Vorobeva, Anastasia D Suslina, Ekaterina V Pechenkova, Olga S Perepelkina, Elena I Kremneva, Marina V Krotenkov. Sensory integration in interoception: Interplay between top-down and bottom-up processing. Cortex; a journal devoted to the study of the nervous system and behavior. vol 144. 2021-11-11. PMID:34673435. |
top-down processing was related to amygdalar connectivity with the rostral prefrontal cortex and an area involving the left frontal opercular and anterior insular cortex, with the latter area being an intersection of the two networks. |
2021-11-11 |
2023-08-13 |
human |
| Frank Scharnowski, Andrew A Nicholson, Swann Pichon, Maria J Rosa, Gwladys Rey, Simon B Eickhoff, Dimitri Van De Ville, Patrik Vuilleumier, Yury Kous. The role of the subgenual anterior cingulate cortex in dorsomedial prefrontal-amygdala neural circuitry during positive-social emotion regulation. Human brain mapping. vol 41. issue 11. 2021-11-10. PMID:32309893. |
it has been shown that the upregulation of positive emotions in social situations is associated with increased top-down signals that stem from the prefrontal cortices (pfc) which modulate bottom-up emotional responses in the amygdala. |
2021-11-10 |
2023-08-13 |
Not clear |
| Adam C Snyder, Byron M Yu, Matthew A Smit. A Stable Population Code for Attention in Prefrontal Cortex Leads a Dynamic Attention Code in Visual Cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 44. 2021-11-10. PMID:34583956. |
moreover, attention signals in pfc predicted the future attention state of v4 better than vice versa, consistent with a top-down role for pfc in attention. |
2021-11-10 |
2023-08-13 |
monkey |
| Sara B Festini, Benjamin Kat. A Frontal Account of False Alarms. Journal of cognitive neuroscience. vol 33. issue 9. 2021-11-04. PMID:34375412. |
prior research has demonstrated that the frontal lobes play a critical role in the top-down control of behavior, and damage to the frontal cortex impairs performance on tasks that require executive control [burgess, p. w., & stuss, d. t. fifty years of prefrontal cortex research: impact on assessment. |
2021-11-04 |
2023-08-13 |
Not clear |
| Atsushi Matsumoto, Takahiro Soshi, Norio Fujimaki, Aya S Ihar. Distinctive responses in anterior temporal lobe and ventrolateral prefrontal cortex during categorization of semantic information. Scientific reports. vol 11. issue 1. 2021-11-03. PMID:34172800. |
the combination of bottom-up processing based on semantic characteristics in the left anterior temporal lobe and top-down processing based on task and/or context specific information in the left ventrolateral prefrontal cortex is required for the flexible categorization of semantic information. |
2021-11-03 |
2023-08-13 |
human |
| Xiaoliang Luo, Brett D Roads, Bradley C Lov. The Costs and Benefits of Goal-Directed Attention in Deep Convolutional Neural Networks. Computational brain & behavior. vol 4. issue 2. 2021-11-02. PMID:34723095. |
in that light, our attentional mechanism incorporates top-down influences from prefrontal cortex (pfc) to support goal-directed behaviour. |
2021-11-02 |
2023-08-13 |
Not clear |
| Rui Jing, Chen Yang, Xin Huang, Wu L. Perceptual learning as a result of concerted changes in prefrontal and visual cortex. Current biology : CB. vol 31. issue 20. 2021-10-27. PMID:34450086. |
one component was closely related to the target stimulus feature and was subject to task-dependent top-down modulation; it emerged earlier in v4 than pfc and its enhancement was specific to the trained configuration of the target stimulus. |
2021-10-27 |
2023-08-13 |
human |
| Michael Vaninetti, Mike Lim, Aladdin Khalaf, Valerie Metzger-Smith, Matthew Flowers, Alphonsa Kunnel, Eric Yang, David Song, Lisa Lin, Alice Tsai, Roland Lee, Shahrokh Golshan, Albert Leun. fMRI findings in MTBI patients with headaches following rTMS. Scientific reports. vol 11. issue 1. 2021-10-22. PMID:33953315. |
this study correlates the demonstrated analgesic effect of rtms in the treatment of mtbi-ha with enhanced supraspinal functional connectivity in the left prefrontal cortex, which is known to be involved in "top-down" pain inhibition along the descending midbrain-thalamic-cingulate pathway. |
2021-10-22 |
2023-08-13 |
human |
| Jeremy E Solly, Roxanne W Hook, Jon E Grant, Samuele Cortese, Samuel R Chamberlai. Structural gray matter differences in Problematic Usage of the Internet: a systematic review and meta-analysis. Molecular psychiatry. 2021-10-22. PMID:34642454. |
in conclusion, voxel-based morphometric studies indicate replicable gray matter reductions in the dorsolateral prefrontal cortex and anterior cingulate cortex in pui, regions implicated in reward processing and top-down inhibitory control. |
2021-10-22 |
2023-08-13 |
Not clear |
| Mariella Paul, Claudia Männel, Anne van der Kant, Jutta L Mueller, Barbara Höhle, Isabell Wartenburger, Angela D Friederic. Gradual development of non-adjacent dependency learning during early childhood. Developmental cognitive neuroscience. vol 50. 2021-10-19. PMID:34139635. |
neuroanatomically, maturation of the prefrontal cortex might play a crucial role, promoting top-down learning, affecting bottom-up, associative learning. |
2021-10-19 |
2023-08-13 |
Not clear |
| Michael C Anderson, Justin C Hulber. Active Forgetting: Adaptation of Memory by Prefrontal Control. Annual review of psychology. vol 72. 2021-10-05. PMID:32928060. |
a core discovery concerns the role of the prefrontal cortex in exerting top-down control over mnemonic activity in the hippocampus and other brain structures, often via inhibitory control. |
2021-10-05 |
2023-08-13 |
Not clear |
| Michael R Duggan, Surbhi Joshi, Jacob Strupp, Vinay Parik. Chemogenetic inhibition of prefrontal projection neurons constrains top-down control of attention in young but not aged rats. Brain structure & function. vol 226. issue 7. 2021-10-05. PMID:34247267. |
the prefrontal cortex (pfc) governs top-down control of attention and is known to be vulnerable in aging. |
2021-10-05 |
2023-08-13 |
human |
| Michael R Duggan, Surbhi Joshi, Jacob Strupp, Vinay Parik. Chemogenetic inhibition of prefrontal projection neurons constrains top-down control of attention in young but not aged rats. Brain structure & function. vol 226. issue 7. 2021-10-05. PMID:34247267. |
collectively, our findings suggest a reduced efficiency of pfc-mediated top-down control of attention and cholinergic system in aging, and that activity of pfc output neurons does not reflect compensation in aged rats, at least in the attention domain. |
2021-10-05 |
2023-08-13 |
human |
| J Alex Grizzell, Thomas T Clarity, Nate B Graham, Brooke N Dulka, Matthew A Coope. Activity of a vmPFC-DRN Pathway Corresponds With Resistance to Acute Social Defeat Stress. Frontiers in neural circuits. vol 14. 2021-10-04. PMID:33177993. |
the ventromedial prefrontal cortex (vmpfc) plays a critical role in stress resilience through top-down inhibition of key stress-sensitive limbic and hindbrain structures, including the dorsal raphe nucleus (drn). |
2021-10-04 |
2023-08-13 |
Not clear |
| Amy F T Arnste. Guanfacine's mechanism of action in treating prefrontal cortical disorders: Successful translation across species. Neurobiology of learning and memory. vol 176. 2021-09-27. PMID:33075480. |
the pfc subserves high order cognitive and executive functions including working memory, abstract reasoning, insight and judgment, and top-down control of attention, action and emotion. |
2021-09-27 |
2023-08-13 |
Not clear |
| Elizabeth Woo, Lauren H Sansing, Amy F T Arnsten, Dibyadeep Datt. Chronic Stress Weakens Connectivity in the Prefrontal Cortex: Architectural and Molecular Changes. Chronic stress (Thousand Oaks, Calif.). vol 5. 2021-09-20. PMID:34485797. |
chronic exposure to uncontrollable stress causes loss of spines and dendrites in the prefrontal cortex (pfc), a recently evolved brain region that provides top-down regulation of thought, action, and emotion. |
2021-09-20 |
2023-08-13 |
Not clear |
| Elizabeth Woo, Lauren H Sansing, Amy F T Arnsten, Dibyadeep Datt. Chronic Stress Weakens Connectivity in the Prefrontal Cortex: Architectural and Molecular Changes. Chronic stress (Thousand Oaks, Calif.). vol 5. 2021-09-20. PMID:34485797. |
pfc neurons generate top-down goals through recurrent excitatory connections on spines. |
2021-09-20 |
2023-08-13 |
Not clear |
| Kaho Tsumura, Keita Kosugi, Yoshiki Hattori, Ryuta Aoki, Masaki Takeda, Junichi Chikazoe, Kiyoshi Nakahara, Koji Jimur. Reversible Fronto-occipitotemporal Signaling Complements Task Encoding and Switching under Ambiguous Cues. Cerebral cortex (New York, N.Y. : 1991). 2021-09-14. PMID:34519334. |
when relevant behavior is cued ambiguously during behavioral shifting, neural coding is attenuated in distributed cortical regions, but top-down signals from the prefrontal cortex complement the coding. |
2021-09-14 |
2023-08-13 |
Not clear |