| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Hodges, Y Allen, T Kershaw, P L Lantos, J A Gray, J Sinde. Effects of cholinergic-rich neural grafts on radial maze performance of rats after excitotoxic lesions of the forebrain cholinergic projection system--I. Amelioration of cognitive deficits by transplants into cortex and hippocampus but not into basal forebrain. Neuroscience. vol 45. issue 3. 1992-03-04. PMID:1775235. |
after ibotenate (10.0 mg/ml) lesions to the nucleus basalis and medial septal regions, at the source of the cortical and hippocampal branches of the forebrain cholinergic projection system, rats displayed long-lasting stable impairment in reference and working memory in both spatial (place) and associative (cue) radial maze tasks. |
1992-03-04 |
2023-08-11 |
rat |
| M M'Harzi, L E Jarrard, F Willig, A Palacios, J Delacou. Selective fimbria and thalamic lesions differentially impair forms of working memory in rats. Behavioral and neural biology. vol 56. issue 3. 1992-02-06. PMID:1759943. |
these data may contribute two main points to animal models of hippocampal and thalamic amnesia: (1) different forms of working memory in rats might have different neural bases and (2) the fr may be involved in learning and memory processes. |
1992-02-06 |
2023-08-11 |
rat |
| J Shimizu, M Tamaru, T Katsukura, T Matsutani, Y Nagat. Effects of fetal treatment with methylazoxymethanol acetate on radial maze performance in rats. Neuroscience research. vol 11. issue 3. 1992-01-31. PMID:1661872. |
these results suggest that working memory disorders of mam rats on radial maze tasks may be due to the lowering of cholinergic functions in their hippocampus and cerebral cortex. |
1992-01-31 |
2023-08-11 |
rat |
| Z J van Hulzen, F J van der Staa. Spatial memory processing during hippocampal long-term potentiation in rats. Physiology & behavior. vol 50. issue 1. 1991-12-17. PMID:1658829. |
evaluation of radial maze data revealed a marginal improvement of working memory performance in the experimental group during the rising phase of hippocampal ltp. |
1991-12-17 |
2023-08-11 |
human |
| P Riekkinen, M Aaltonen, J Sirviö, P Riekkine. Tetrahydroaminoacridine alleviates medial septal lesion-induced and age-related spatial reference but not working memory deficits. Physiology & behavior. vol 49. issue 6. 1991-10-23. PMID:1896495. |
ms lesions decreased cholineacetyltransferase activity in the hippocampus and also impaired spatial reference and working memory. |
1991-10-23 |
2023-08-11 |
rat |
| P Riekkinen, M Aaltonen, J Sirviö, P Riekkine. Tetrahydroaminoacridine alleviates medial septal lesion-induced and age-related spatial reference but not working memory deficits. Physiology & behavior. vol 49. issue 6. 1991-10-23. PMID:1896495. |
the present results suggest that some of the age-related wm deficits may be related to the degeneration of the ms-hippocampus cholinergic system and that tha may be effective in stabilizing the reference memory deficits induced by hippocampal cholinergic dysfunction. |
1991-10-23 |
2023-08-11 |
rat |
| A J Strong, J E Fairfield, E Monteiro, M Kirby, A R Hogg, M Snape, L Ross-Fiel. Insulin protects cognitive function in experimental stroke. Journal of neurology, neurosurgery, and psychiatry. vol 53. issue 10. 1991-02-08. PMID:2266364. |
rats learned a maze task as a test of working memory, believed to be subserved by the hippocampus, and then had a period of cerebral ischaemia, followed by reperfusion. |
1991-02-08 |
2023-08-11 |
rat |
| D F Emerich, T J Wals. Ganglioside AGF2 promotes task-specific recovery and attenuates the cholinergic hypofunction induced by AF64A. Brain research. vol 527. issue 2. 1991-01-24. PMID:2253037. |
thus the behavioral recovery afforded by agf2 might be related to increased cholinergic activity in the hippocampus that is sufficient for the performance of tasks which either lack or have a minimal working memory component. |
1991-01-24 |
2023-08-11 |
rat |
| T Kadar, M Silbermann, B A Weissman, A Lev. Age-related changes in the cholinergic components within the central nervous system. II. Working memory impairment and its relation to hippocampal muscarinic receptors. Mechanisms of ageing and development. vol 55. issue 2. 1990-12-18. PMID:2232908. |
working memory impairment and its relation to hippocampal muscarinic receptors. |
1990-12-18 |
2023-08-11 |
rat |
| M A Peinado-Manzan. The role of the amygdala and the hippocampus in working memory for spatial and non-spatial information. Behavioural brain research. vol 38. issue 2. 1990-08-13. PMID:2363833. |
the role of the amygdala and the hippocampus in working memory for spatial and non-spatial information. |
1990-08-13 |
2023-08-11 |
rat |
| M A Peinado-Manzan. The role of the amygdala and the hippocampus in working memory for spatial and non-spatial information. Behavioural brain research. vol 38. issue 2. 1990-08-13. PMID:2363833. |
the contribution of the amygdala and the hippocampus in the working memory for spatial and non-spatial information is discussed. |
1990-08-13 |
2023-08-11 |
rat |
| T Kadar, M Silbermann, R Brandeis, A Lev. Age-related structural changes in the rat hippocampus: correlation with working memory deficiency. Brain research. vol 512. issue 1. 1990-06-21. PMID:2337798. |
age-related structural changes in the rat hippocampus: correlation with working memory deficiency. |
1990-06-21 |
2023-08-11 |
rat |
| A Marighetto, T Durkin, A Toumane, C Lebrun, R Jaffar. Septal alpha-noradrenergic antagonism in vivo blocks the testing-induced activation of septo-hippocampal cholinergic neurones and produces a concomitant deficit in working memory performance of mice. Pharmacology, biochemistry, and behavior. vol 34. issue 3. 1990-03-26. PMID:2560206. |
neurochemical analysis was performed using measures of the kinetics of sodium-dependent high-affinity choline uptake in samples of hippocampus from injected mice and their relevant controls in both quiet conditions and immediately following selective working memory testing in an 8-arm radial maze. |
1990-03-26 |
2023-08-11 |
mouse |
| W H Meck, R A Smith, C L William. Organizational changes in cholinergic activity and enhanced visuospatial memory as a function of choline administered prenatally or postnatally or both. Behavioral neuroscience. vol 103. issue 6. 1990-03-08. PMID:2610916. |
an analysis of the relationship between these organizational changes in brain and memory function indicated that the chat-to-qnb ratio in the hippocampus is highly correlated with working memory errors, and this ratio in the frontal cortex is highly correlated with reference memory errors. |
1990-03-08 |
2023-08-11 |
rat |
| D M Rosenbaum, J C Grotta, L C Pettigrew, P Ostrow, R Strong, H Rhoades, C M Picone, A T Grott. Baclofen does not protect against cerebral ischemia in rats. Stroke. vol 21. issue 1. 1990-03-05. PMID:2300981. |
we evaluated the effect of baclofen, a selective inhibitor of presynaptic glutamate release, on mortality, working memory, and light microscopic hippocampal and cortical damage in the four-vessel occlusion model of cerebral ischemia using 64 male wistar rats. |
1990-03-05 |
2023-08-11 |
rat |
| B T Volpe, H P Davis, P J Colomb. Preoperative training modifies radial maze performance in rats with ischemic hippocampal injury. Stroke. vol 20. issue 12. 1990-01-19. PMID:2595733. |
rats exposed to 30 minutes of four-vessel occlusion reliably develop severe bilateral ca1 hippocampal injury; under certain conditions of radial maze training, such rats perform the reference memory component as well as controls yet perform the working memory component worse than controls. |
1990-01-19 |
2023-08-11 |
rat |
| S J Mizumori, B L McNaughton, C A Barnes, K B Fo. Preserved spatial coding in hippocampal CA1 pyramidal cells during reversible suppression of CA3c output: evidence for pattern completion in hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 9. issue 11. 1990-01-03. PMID:2585060. |
medial septal modulation of hippocampal single-unit activity was examined by assessing the behavioral and physiological consequences of reversibly inactivating the medial septum via microinjection of a local anesthetic (tetracaine) in freely behaving rats trained to solve a working memory problem on a radial maze. |
1990-01-03 |
2023-08-11 |
rat |
| B J Knowlton, M L Shapiro, D S Olto. Hippocampal seizures disrupt working memory performance but not reference memory acquisition. Behavioral neuroscience. vol 103. issue 5. 1989-12-19. PMID:2803557. |
hippocampal seizures disrupt working memory performance but not reference memory acquisition. |
1989-12-19 |
2023-08-11 |
rat |
| B J Knowlton, M L Shapiro, D S Olto. Hippocampal seizures disrupt working memory performance but not reference memory acquisition. Behavioral neuroscience. vol 103. issue 5. 1989-12-19. PMID:2803557. |
in the working memory task, hippocampal seizures did impair performance in a group of the same rats. |
1989-12-19 |
2023-08-11 |
rat |
| B J Knowlton, M L Shapiro, D S Olto. Hippocampal seizures disrupt working memory performance but not reference memory acquisition. Behavioral neuroscience. vol 103. issue 5. 1989-12-19. PMID:2803557. |
these results support the distinction between a trial-dependent working memory system that requires hippocampal function and a trial-independent memory system that does not depend on hippocampal function. |
1989-12-19 |
2023-08-11 |
rat |