| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Recio, P Pévet, M Masson-Péve. Serotonergic modulation of photically induced increase in melatonin receptor density and Fos immunoreactivity in the suprachiasmatic nuclei of the rat. Journal of neuroendocrinology. vol 8. issue 11. 1997-03-03. PMID:8933361. |
the aim of this study was to assess whether, in rats, these two phenomena were regulated by serotonin, acting via 5-ht1a receptors. |
1997-03-03 |
2023-08-12 |
rat |
| M G Swain, M Mari. Improvement in cholestasis-associated fatigue with a serotonin receptor agonist using a novel rat model of fatigue assessment. Hepatology (Baltimore, Md.). vol 25. issue 2. 1997-03-03. PMID:9021936. |
therefore, we used bdr and noncholestatic control rats to examine the effects of a serotonin (5ht1a) receptor agonist (ly293284) on cholestasis-associated fatigue. |
1997-03-03 |
2023-08-12 |
rat |
| M Bijak, K Tokarski, A Czyrak, M Maćkowiak, K Wedzon. Imipramine increases the 5-HT1A receptor-mediated inhibition of hippocampal neurons without changing the 5-HT1A receptor binding. European journal of pharmacology. vol 305. issue 1-3. 1997-02-20. PMID:8813535. |
serotonin (5-hydroxytryptamine, 5-ht) and the selective 5-ht1a receptor agonist 8-hydroxy-2-(dipropylamino)tetralin (8-oh-dpat) decreased dose-dependently the amplitude of population spikes; this effect was blocked by the selective 5-ht1a receptor antagonist (s)-n-tert-butyl-3-[4-(2-methoxyphenyl)piperazin-1-yl]-2-phenylpro panamide dihydrochloride [(s)-way 100135]. |
1997-02-20 |
2023-08-12 |
rat |
| A Merzak, S Koochekpour, M P Fillion, G Fillion, G J Pilkingto. Expression of serotonin receptors in human fetal astrocytes and glioma cell lines: a possible role in glioma cell proliferation and migration. Brain research. Molecular brain research. vol 41. issue 1-2. 1997-02-20. PMID:8883928. |
expression of seven serotonin or 5-hydroxytryptamine (5-ht) receptors (5-ht1d alpha, 5-ht1e, 5-ht2, 5-ht1a, 5-ht1c, 5-ht1d beta, and 5-ht6) was investigated in human normal fetal astrocytes and eight glioma cell lines by reverse transcription and polymerase chain reaction (rt-pcr). |
1997-02-20 |
2023-08-12 |
human |
| R D Mooney, X Huang, M Y Shi, C A Bennett-Clarke, R W Rhoade. Serotonin modulates retinotectal and corticotectal convergence in the superior colliculus. Progress in brain research. vol 112. 1997-02-19. PMID:8979820. |
in recordings of superficial layer neurons from sc slices, application of 5-ht during blockade of 5-ht1a receptors with spiperone reduced the amplitude of epsps evoked by stimulation of the optic tract. |
1997-02-19 |
2023-08-12 |
Not clear |
| F F Matos, C Urban, F D Yocc. Serotonin (5-HT) release in the dorsal raphé and ventral hippocampus: raphé control of somatodendritic and terminal 5-HT release. Journal of neural transmission (Vienna, Austria : 1996). vol 103. issue 1-2. 1997-02-18. PMID:9026372. |
these data provide evidence that 5-ht release in the dorsal raphé is dependent on the opening of fast activated sodium channels and that dorsal raphé 5-ht1a receptors control somatodendritic and hippocampal 5-ht release |
1997-02-18 |
2023-08-12 |
rat |
| B Wilken, P Lalley, A M Bischoff, H J Christen, J Behnke, F Hanefeld, D W Richte. Treatment of apneustic respiratory disturbance with a serotonin-receptor agonist. The Journal of pediatrics. vol 130. issue 1. 1997-02-14. PMID:9003856. |
apneustic patterns can be consistently converted to normal by administration of serotonin type 1a (5-ht1a) receptor agonists. |
1997-02-14 |
2023-08-12 |
rat |
| S B Kasture, S N Mandhane, C T Chopd. Baclofen-induced catatonia: modification by serotonergic agents. Neuropharmacology. vol 35. issue 5. 1997-02-13. PMID:8887967. |
the 5-ht releaser fenfluramine (10 mg/kg) and the uptake inhibitor fluoxetine (10 mg/kg) reversed, whereas the 5-ht1a agonist buspirone (3 mg/kg) potentiated baclofen-induced catatonia. |
1997-02-13 |
2023-08-12 |
rat |
| G Griebel, D C Blanchard, M C Rettori, B Guardiola-Lemaître, R J Blanchar. Preclinical profile of the mixed 5-HT1A/5-HT2A receptor antagonist S 21,357. Pharmacology, biochemistry, and behavior. vol 54. issue 2. 1997-02-12. PMID:8743616. |
the drug behaved as antagonist at both 5-ht1a autoreceptors and postsynaptic 5-ht1a receptors, as it prevented the inhibitory effect of lesopitron on the electrical discharge of the dorsal raphé nucleus (drn) 5-ht neurons and the activity of forskolin-stimulated adenylate cyclase in hippocampal homogenates. |
1997-02-12 |
2023-08-12 |
mouse |
| M B Assié, W Koe. Effects of 5-HT1A receptor antagonists on hippocampal 5-hydroxytryptamine levels: (S)-WAY100135, but not WAY100635, has partial agonist properties. European journal of pharmacology. vol 304. issue 1-3. 1997-02-12. PMID:8813579. |
effects of 5-ht1a receptor antagonists on hippocampal 5-hydroxytryptamine levels: (s)-way100135, but not way100635, has partial agonist properties. |
1997-02-12 |
2023-08-12 |
rat |
| M B Assié, W Koe. Effects of 5-HT1A receptor antagonists on hippocampal 5-hydroxytryptamine levels: (S)-WAY100135, but not WAY100635, has partial agonist properties. European journal of pharmacology. vol 304. issue 1-3. 1997-02-12. PMID:8813579. |
in vivo microdialysis measuring 5-hydroxytryptamine (5-ht) levels in the ventral hippocampus of chloral hydrate-anaesthetised rats was used to characterise further the recently described 5-ht1a receptor antagonists (s)-way100135 ((s)-n-tert-butyl-3-(4-(2-methoxyphenyl)piperazine-1-yl)-2- phenylpropanamide) and way100635 (n-[2-[4-(2-methoxyphenyl)-1-piperazinyl] ethyl]-n-(2-pyridinyl)cyclohexanecarboxamide). |
1997-02-12 |
2023-08-12 |
rat |
| M B Assié, W Koe. Effects of 5-HT1A receptor antagonists on hippocampal 5-hydroxytryptamine levels: (S)-WAY100135, but not WAY100635, has partial agonist properties. European journal of pharmacology. vol 304. issue 1-3. 1997-02-12. PMID:8813579. |
the effects of (s)-way100135 (0.63-20 mg/kg) and of way100635 (0.0025-0.16 mg/kg) on 5-ht levels were examined alone, and in combination with the 5-ht1a receptor agonist, (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat). |
1997-02-12 |
2023-08-12 |
rat |
| M B Assié, W Koe. Effects of 5-HT1A receptor antagonists on hippocampal 5-hydroxytryptamine levels: (S)-WAY100135, but not WAY100635, has partial agonist properties. European journal of pharmacology. vol 304. issue 1-3. 1997-02-12. PMID:8813579. |
these results are further evidence that (s)-way100135 may modulate the release of 5-ht by acting as a partial agonist at somatodendritic 5-ht1a receptors. |
1997-02-12 |
2023-08-12 |
rat |
| R W Fuller, K W Perry, S K Hemrick-Luecke, E Englema. Serum corticosterone increases reflect enhanced uptake inhibitor-induced elevation of extracellular 5-hydroxytryptamine in rat hypothalamus. The Journal of pharmacy and pharmacology. vol 48. issue 1. 1997-02-11. PMID:8722499. |
the increase in extracellular 5-hydroxytryptamine (5-ht) in rat hypothalamus following administration of fluoxetine, a 5-ht-uptake inhibitor, was enhanced by the injection of ly206130(1-[1-h-indol-4-yloxy]-3-[cyclohexylamino]-2-prop ano l maleate), a 5ht1a receptor antagonist, or by l-5-hydroxytryptophan (l-5-htp), the 5-ht precursor. |
1997-02-11 |
2023-08-12 |
rat |
| R W Fuller, K W Perry, S K Hemrick-Luecke, E Englema. Serum corticosterone increases reflect enhanced uptake inhibitor-induced elevation of extracellular 5-hydroxytryptamine in rat hypothalamus. The Journal of pharmacy and pharmacology. vol 48. issue 1. 1997-02-11. PMID:8722499. |
synergism between effects of fluoxetine and l-5htp has often been reported, but this is the first report of an increased functional effect when a 5-ht1a receptor antagonist is combined with a 5-ht uptake inhibitor to augment the increase in extracellular 5-ht. |
1997-02-11 |
2023-08-12 |
rat |
| N K Popova, A V Kulikov, D F Avgustinovich, S N Shigantso. [The characteristics of the brain serotonin system and anxiety in the C57BL and CBA mouse strains]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 46. issue 2. 1997-02-11. PMID:8726569. |
serotonin metabolism and 5-ht2a and 5-ht1a specific binding were studied in high-aggressive c57bl and low-aggressive cba mice. |
1997-02-11 |
2023-08-12 |
mouse |
| P J Nathan, T R Norman, G D Burrow. Nocturnal plasma melatonin concentrations in healthy volunteers: effect of single doses of d-fenfluramine, paroxetine, and ipsapirone. Journal of pineal research. vol 21. issue 2. 1997-02-10. PMID:8912230. |
the effect on nocturnal melatonin secretion of acute administration of the indirectly acting serotonin (5-ht) receptor agonists d-fenfluramine (30 mg) and paroxetine (20 mg) and a partial 5-ht1a receptor agonist ipsapirone (20 mg) was investigated in healthy male volunteers and compared to a placebo condition. |
1997-02-10 |
2023-08-12 |
human |
| M R MacLean, R A Clayton, A G Templeton, I Morecrof. Evidence for 5-HT1-like receptor-mediated vasoconstriction in human pulmonary artery. British journal of pharmacology. vol 119. issue 2. 1997-02-06. PMID:8886409. |
responses to the agonists 5-carboximidotryptamine (5-ct, non-selective 5-ht1 agonist), sumatriptan (5-ht1d-like receptor agonist), 5-ht and 8-hydroxy-2-(di-n-propylamino)-tetralin (8-oh-dpat, 5-ht1a receptor agonist) were studied. |
1997-02-06 |
2023-08-12 |
human |
| P D Walker, J G Capodilupo, W A Wolf, L R Carloc. Preprotachykinin and preproenkephalin mRNA expression within striatal subregions in response to altered serotonin transmission. Brain research. vol 732. issue 1-2. 1997-02-06. PMID:8891265. |
first, rats received daily intraperitoneal injections of saline or the 5-ht1a receptor agonist, 8-oh-dpat (1 mg/kg), for 7 days to reduce 5-ht release from raphestriatal terminals. |
1997-02-06 |
2023-08-12 |
rat |
| A P Albert, K M Spyer, P A Brook. The effect of 5-HT and selective 5-HT receptor agonists and antagonists on rat dorsal vagal preganglionic neurones in vitro. British journal of pharmacology. vol 119. issue 3. 1997-02-06. PMID:8894172. |
the 5-ht1a receptor antagonist, pindobind 5-ht1a (5 microm), had no effect on the depolarizing response to 5-ht. |
1997-02-06 |
2023-08-12 |
rat |