| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Antônio Marcos de Oliveira Dos Santos, Antônia Eliene Duarte, Adrielle Rodrigues Costa, Aleson Aparecido da Silva, Claudia Rohde, Danúbia Guimarães Silva, Érima Maria de Amorim, Maria Helena da Cruz Santos, Maria Gislaine Pereira, Maríndia Deprá, Samuel Lima de Santana, Vera Lúcia da Silva Valente, Claudener Souza Teixeir. Canavalia ensiformis lectin induced oxidative stress mediate both toxicity and genotoxicity in Drosophila melanogaster. International journal of biological macromolecules. 2022-10-13. PMID:36228819. |
the data show that native cona affected: the survival, in the order of 30.6 %, and the locomotor performance of the flies; reduced cell viability to levels below 50 % (4.4 and 17.5 μg/ml); reduced nitric oxide levels; caused lipid peroxidation and increased protein and non-protein thiol content. |
2022-10-13 |
2023-08-14 |
drosophila_melanogaster |
| Nouf M Alyami, Rafa Almeer, Hanadi M Alyam. Protective effects of Asparagus officinalis (asparagus) against lead toxicity in mice. Environmental science and pollution research international. 2022-10-11. PMID:36219290. |
in the biochemical analysis of testicular tissue, pbac decreased enzymatic and nonenzymatic antioxidant molecules in testicular tissue, while increasing lipid peroxidation, nitric oxide, inflammatory markers [nuclear factor kappa-b (nf-κb), tumor necrosis factor-alpha (tnf-α), interleukin-1beta (il-1 β), il-6, and inducible nitric oxide synthase (inos)], and apoptotic-related proteins. |
2022-10-11 |
2023-08-14 |
mouse |
| Tarfa Albrahim, Maram H M Alotaibi, Norah M M Altamimi, Atheer M A Albariqi, Lamees A O Alqarni, Sara N A Alassaf, Hisham S Aloudah, Mohammed Alahmed, Ahmad T Almnaizel, Maha R Aldraihem, Mona Alonaz. The Impact of Dietary Consumption of Palm Oil and Olive Oil on Lipid Profile and Hepatocyte Injury in Hypercholesterolemic Rats. Pharmaceuticals (Basel, Switzerland). vol 15. issue 9. 2022-09-23. PMID:36145324. |
additionally, hcd significantly increased the production of nitric oxide and lipid peroxidation in the liver while decreasing antioxidant enzymes. |
2022-09-23 |
2023-08-14 |
mouse |
| Ajay Guru, Jesu Arockiara. Exposure to environmental pollutant bisphenol A causes oxidative damage and lipid accumulation in Zebrafish larvae: Protective role of WL15 peptide derived from cysteine and glycine-rich protein 2. Journal of biochemical and molecular toxicology. 2022-09-15. PMID:36106391. |
bpa exposure disrupted the antioxidant enzymes, apoptosis, and nitric oxide and led to changes in biochemical markers including alkaline phosphatase, lactate dehydrogenase, lipid peroxidation, glutathione s-transferases, glutathione peroxidase, and reduced glutathione. |
2022-09-15 |
2023-08-14 |
zebrafish |
| Raghul Murugan, Ravi Rajesh, Ajay Guru, B Haridevamuthu, Bader O Almutairi, Mikhlid H Almutairi, Annie Juliet, S Renganayagi, Pushparathinam Gopinath, Jesu Arockiara. Deacetylepoxyazadiradione Derived from Epoxyazadiradione of Neem (Azadirachta indica A. Juss) Fruits Mitigates LPS-Induced Oxidative Stress and Inflammation in Zebrafish Larvae. Chemistry & biodiversity. 2022-08-26. PMID:36026548. |
the percentage of ros, lipid peroxidation, nitric oxide and apoptosis were reduced significantly in nf2 treated lps-stressed zebrafish larvae. |
2022-08-26 |
2023-08-14 |
rat |
| George J Clark, Kashyap Pandya, Cesar A Lau-Ca. Assessment of In Vitro Tests as Predictors of the Antioxidant Effects of Insulin, Metformin, and Taurine in the Brain of Diabetic Rats. Advances in experimental medicine and biology. vol 1370. 2022-07-26. PMID:35882800. |
unexpectedly, however, all three compounds reduced the diabetic values for brain lpo, nitric oxide, antioxidant enzymes, glutathione, and glutathione-related enzymes to values that varied in extent within a narrow range (<12% from one another). |
2022-07-26 |
2023-08-14 |
rat |
| Vagdevi Hangarakatte Ramachandra, Senthilkumar Sivanesan, Anand Koppal, Shanmugam Anandakumar, Matthew D Howell, Ethirajan Sukumar, Rajagopalan Vijayaraghava. Embelin and levodopa combination therapy for improved Parkinson's disease treatment. Translational neuroscience. vol 13. issue 1. 2022-07-20. PMID:35855085. |
at the end of experimentation, the mice were sacrificed and the midbrain was used to evaluate various biochemical parameters, such as nitric oxide, peroxynitrite, urea, and lipid peroxidation. |
2022-07-20 |
2023-08-14 |
mouse |
| Hanif Ali, Rumana Yesmin Hasi, Majidul Islam, Md Shajedul Haque, Mustfa F Alkhanani, Atiah H Almalki, Shafiul Haque, R Z Sayyed, Tanzima Yeasmi. Antioxidant, cytotoxic and apoptotic activities of the rhizome of Zingiber zerumbet Linn. in Ehrlich ascites carcinoma bearing Swiss albino mice. Scientific reports. vol 12. issue 1. 2022-07-15. PMID:35840634. |
the rich polyphenol containing mezzr showed a marked dpph, abts, nitric oxide radicals and lipid peroxidation inhibition activity with an ic |
2022-07-15 |
2023-08-14 |
mouse |
| Gamze Bayrak, Ismet Burcu Turkyilmaz, Refiye Yanarda. The protective effect of vitamin U on pentylenetetrazole-induced brain damage in rats. Journal of biochemical and molecular toxicology. 2022-07-14. PMID:35833322. |
in the ptz group, glutathione and lipid peroxidation levels, alkaline phosphatase, myeloperoxidase, xanthine oxidase, acetylcholine esterase, antioxidant enzyme activities, total oxidant status, oxidative stress index, reactive oxygen species, and nitric oxide levels were increased. |
2022-07-14 |
2023-08-14 |
rat |
| Md Ashrafur Rahman, Arif Anzum Shuvo, Asim Kumar Bepari, Mehedi Hasan Apu, Manik Chandra Shill, Murad Hossain, Mohammed Uddin, Md Rabiul Islam, Monjurul Kader Bakshi, Javed Hasan, Atiqur Rahman, Ghazi Mohammad Sayedur Rahman, Hasan Mahmud Rez. Curcumin improves D-galactose and normal-aging associated memory impairment in mice: In vivo and in silico-based studies. PloS one. vol 17. issue 6. 2022-06-29. PMID:35767571. |
curcumin profoundly ameliorated the levels of glutathione, superoxide dismutase, catalase, advanced oxidation protein products, nitric oxide, and lipid peroxidation in mice hippocampi. |
2022-06-29 |
2023-08-14 |
mouse |
| Mahak Singh, R Talimoa Mollier, Nungshitula Pongener, L J Bordoloi, Rakesh Kumar, J K Chaudhary, Rahul Katiyar, M H Khan, D J Rajkhowa, V K Mishr. Linseed oil in boar's diet during high temperature humidity index (THI) period improves sperm quality characteristics, antioxidant status and fatty acid composition of sperm under hot humid sub-tropical climate. Theriogenology. vol 189. 2022-06-26. PMID:35753226. |
antioxidants (glutathione peroxidase; gpx, catalase; cat, total antioxidant capacity; tac and nitric oxide; no) and lipid peroxidation (malondialdehyde; mda) were measured in seminal plasma and serum. |
2022-06-26 |
2023-08-14 |
cat |
| Mojdeh Mohammadi, Saba Ariafar, Elaheh Talebi-Ghane, Saeed Afzal. Comparative Efficacy of Silibinin and Nano-Silibinin on Lead poisoning in Male Wistar Rats. Toxicology. 2022-06-25. PMID:35752206. |
lead-induced elevation of lipid peroxidation products (mda) and nitric oxide (no) normalized to the standard level in silibinin and especially nano-silibinin groups. |
2022-06-25 |
2023-08-14 |
rat |
| Anandha R Ravula, Suresh Yenug. Effect of a mixture of pyrethroids at doses similar to human exposure through food in the Indian context. Journal of biochemical and molecular toxicology. 2022-06-09. PMID:35678313. |
the oxidant-antioxidant status (lipid peroxidation, nitric oxide; activities of catalase, glutathione peroxidase, glutathione s transferase, and superoxide dismutase) and anatomical changes in the general organs (liver, lung, and kidney) and male reproductive tract tissues (caput, cauda, testis, and prostate) were evaluated. |
2022-06-09 |
2023-08-14 |
human |
| Oluwakemi D Samuel, Joseph A Adeyemi, Olufemi S Bamidele, Fernando Barbosa, Chris O Adedir. Cytotoxicity, redox and immune status in African catfish, Clarias gariepinus (Burchell, 1822) exposed to bisphenol A (BPA) and its analogues. Environmental science and pollution research international. 2022-05-31. PMID:35635660. |
the exposed fish had increased levels of dna fragmentation, lipid peroxidation, white blood cells, nitric oxide and respiratory burst, while the red blood cell counts and the percentage packed cell volume decreased significantly in the exposed fish compared to control. |
2022-05-31 |
2023-08-13 |
Not clear |
| Amira A Sallam, Mohammed A El-Magd, Mona M Ahmed, Heba I Ghamry, Mohammad Y Alshahrani, Rabab A Hegazy, Ahmed Magdy, Magdy F Abou El-Foto. Quercetin alleviated multi-walled carbon nanotubes-induced neurotoxicity in mice through inhibition of oxidation, inflammation, and pyroptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 151. 2022-05-23. PMID:35605300. |
however, treatment with que ameliorated mwcnts-induced neurotoxicity as revealed by 1) elevated acetylcholinesterase (ache) activity, 2) reduced lipid peroxidation biomarker malondialdehyde (mda), 3) improved antioxidant status as indicated by increased levels of reduced glutathione (gsh) and activities of superoxide dismutase (sod), catalase (cat), as well as upregulated expression of nuclear factor erythroid 2-related factor 2 (nrf2) and heme oxygenase-1 (ho-1) genes, 4) decreased levels and expression of inflammatory biomarkers [nitric oxide (no), interleukin 1 beta (il1ß), tumor necrosis factor-alpha (tnfα), and nuclear factor kappa b (nf-κb)], 5) downregulated expression of pyroptosis-related genes [nod-like receptor protein inflammasome 3 (nlrp3) and caspase 1 (casp1)] but with no effect on the apoptotic casp3 gene, 6) minimized axonal degeneration and number of microglia in the cerebral medulla, and 7) diminished the number of degenerated neurons in hippocampus and cerebellum. |
2022-05-23 |
2023-08-13 |
mouse |
| Hichem Moulahoum, Faezeh Ghorbanizamani, Zineb Khiari, Mohamed Toumi, Yasmina Benazzoug, Kerem Tok, Suna Timur, Figen Zihniogl. Artemisia alleviates AGE-induced liver complications via MAPK and RAGE signaling pathways modulation: a combinatorial study. Molecular and cellular biochemistry. 2022-05-11. PMID:35543857. |
next, thle-2 liver cells were challenged with ages, and the mechanistic markers were measured [tnf-α, il-6, nitric oxide, total antioxidant capacity, lipid peroxidation (lpo), and caspase 3]. |
2022-05-11 |
2023-08-13 |
Not clear |
| Ajay Guru, Gokul Sudhakaran, Manikandan Velayutham, Raghul Murugan, R Pachaiappan, Ramzi A Mothana, Omar M Noman, Annie Juliet, Jesu Arockiara. Daidzein normalized gentamicin-induced nephrotoxicity and associated pro-inflammatory cytokines in MDCK and zebrafish: Possible mechanism of nephroprotection. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2022-05-06. PMID:35523404. |
daidzein activity was associated with an increase in antioxidant biomarkers such as superoxide dismutase (sod) and glutathione reductase (gsh), whereas lipid peroxidation (lpo) and nitric oxide (no) production were decreased in a dose-dependent factor. |
2022-05-06 |
2023-08-13 |
zebrafish |
| Tanitoluwa O Oluwabayo, Afolabi C Akinmoladun, Afolabi A Akindahuns. Arrested Acetylene-Induced Pulmonary and Testicular Toxicity in Rats Through Treatment With Polyphenols. Drug and chemical toxicology. 2022-04-22. PMID:35450496. |
at the end of the treatment sessions, the levels of superoxide dismutase, reduced glutathione, glutathione peroxidase, lactate dehydrogenase, and hormonal markers in rats exposed to acetylene were significantly decreased, with a concomitant increase in lipid peroxidation, nitric oxide level, cholesterol concentration, and histopathological abnormalities. |
2022-04-22 |
2023-08-13 |
rat |
| Zalán Czékus, Gabriella Szalai, Irma Tari, M Iqbal R Khan, Péter Poó. Role of ethylene in ER stress and the unfolded protein response in tomato (Solanum lycopersicum L.) plants. Plant physiology and biochemistry : PPB. vol 181. 2022-04-14. PMID:35421744. |
additionally, it was found that nitric oxide production and lipid peroxidation, as well as the electrolyte leakage induced by tm, is regulated by et, whereas the levels of h |
2022-04-14 |
2023-08-13 |
Not clear |
| Lorena Olivares-González, David Salom, Emilio González-García, David Hervás, Natalia Mejía-Chiqui, Mar Melero, Sheyla Velasco, Bianca Tabita Muresan, Isabel Campillo, Nieves Vila-Clérigues, Eduardo López-Briz, Juan Francisco Merino-Torres, José María Millán, José Miguel Soriano Del Castillo, Regina Rodrig. NUTRARET: Effect of 2-Year Nutraceutical Supplementation on Redox Status and Visual Function of Patients With Retinitis Pigmentosa: A Randomized, Double-Blind, Placebo-Controlled Trial. Frontiers in nutrition. vol 9. 2022-04-07. PMID:35387197. |
total antioxidant capacity, extracellular superoxide dismutase (sod3), catalase (cat), and glutathione peroxidase (gpx) activities, protein carbonyl adducts (car) content, thiobarbituric acid reactive substances (tbars) formation (as indicator of lipid peroxidation), metabolites of the nitric oxide (nox) and cytokine (interleukin 6 and tumor necrosis factor alpha) concentrations were assessed by biochemical and immunological techniques in aqueous humor or/and blood. |
2022-04-07 |
2023-08-13 |
cat |