All Relations between magl and cannabinoids
| Publication | Sentence | Publish Date | Extraction Date | Species |
|---|---|---|---|---|
| Séverine Vandevoorde, Bijali Saha, Anu Mahadevan, Raj K Razdan, Roger G Pertwee, Billy R Martin, Christopher J Fowle. Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase. Biochemical and biophysical research communications. vol 337. issue 1. 2005-11-14. PMID:16181610. | little is known as to the structural requirements of the acyl side chain for interaction of acylglycerols with monoacylglycerol lipase (magl), the enzyme chiefly responsible for the metabolism of the endocannabinoid 2-arachidonoylglycerol (2-ag) in the brain. | 2005-11-14 | 2023-08-12 | Not clear |
| Nazdar Ghafouri, Gunnar Tiger, Raj K Razdan, Anu Mahadevan, Roger G Pertwee, Billy R Martin, Christopher J Fowle. Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol. British journal of pharmacology. vol 143. issue 6. 2005-03-29. PMID:15492019. | it is concluded that compounds like alpha-methyl-1-ag, o-2203 and o-2204 may be useful as leads for the discovery of selective magl inhibitors that lack direct effects upon cannabinoid receptors. | 2005-03-29 | 2023-08-12 | Not clear |