| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C A Willson, I Hani. Effect of nerve growth factor in ethylcholine mustard aziridinium (AF64A)-treated rats: sensitization of cholinergic enzyme activity in the septohippocampal pathway. Journal of neurochemistry. vol 65. issue 2. 1995-08-24. PMID:7616246. |
choline acetyltransferase (chat) and acetylcholinesterase activity were measured in the hippocampus and septum of rats chronically administered ngf (0.36-2.85 micrograms/day) into the lateral ventricle for 14 days. |
1995-08-24 |
2023-08-12 |
rat |
| V K Bergdall, J B Becke. Effects of nerve growth factor infusion on behavioral recovery and graft survival following intraventricular adrenal medulla grafts in the unilateral 6-hydroxydopamine lesioned rat. Journal of neural transplantation & plasticity. vol 5. issue 3. 1995-05-30. PMID:7727597. |
ngf was infused into the lateral ventricle of rats with unilateral 6-ohda lesions of the substantia nigra along with adrenal medulla or control grafts. |
1995-05-30 |
2023-08-12 |
rat |
| L G Isaacson, K A Crutche. The duration of sprouted cerebrovascular axons following intracranial infusion of nerve growth factor. Experimental neurology. vol 131. issue 2. 1995-04-27. PMID:7895818. |
we reported previously that a 2-week infusion of the trophic protein nerve growth factor (ngf) into the lateral ventricle of the adult rat brain elicits a sprouting response by perivascular axons associated with the intradural segment of the internal carotid artery. |
1995-04-27 |
2023-08-12 |
rat |
| S Varon, J M Conne. Nerve growth factor in CNS repair. Journal of neurotrauma. vol 11. issue 5. 1995-03-21. PMID:7861441. |
ngf is required in the bridge, enhances penetration of the hippocampal tissue when infused there, and both attracts and promotes sprouting within the septum when infused in the lateral ventricle or the septal tissue itself. |
1995-03-21 |
2023-08-12 |
rat |
| J J Waite, M L Wardlow, A C Chen, D A Lappi, R G Wiley, L J Tha. Time course of cholinergic and monoaminergic changes in rat brain after immunolesioning with 192 IgG-saporin. Neuroscience letters. vol 169. issue 1-2. 1994-09-01. PMID:8047273. |
192 igg-saporin, an immunotoxin targeted at the low affinity ngf receptor, was infused into the lateral ventricle of rat brain. |
1994-09-01 |
2023-08-12 |
rat |
| L Olso. NGF and the treatment of Alzheimer's disease. Experimental neurology. vol 124. issue 1. 1994-02-16. PMID:8282080. |
based on background information from intracerebral infusion of ngf in parkinsonian patients, attempting to support intraputaminal chromaffin tissue grafts, a study was initiated using a radio-controlled fully implantable pumping device delivering ngf to the lateral ventricle. |
1994-02-16 |
2023-08-12 |
Not clear |
| J K Morse, S J Wiegand, K Anderson, Y You, N Cai, J Carnahan, J Miller, P S DiStefano, C A Altar, R M Lindsa. Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 10. 1993-11-12. PMID:8080477. |
bdnf, ngf, or vehicle solutions were infused continuously in adult female rats either into the lateral ventricle (intracerebroventricularly) or directly into the septum for 2 weeks beginning at the time of the transection. |
1993-11-12 |
2023-08-12 |
rat |
| J K Morse, S J Wiegand, K Anderson, Y You, N Cai, J Carnahan, J Miller, P S DiStefano, C A Altar, R M Lindsa. Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 10. 1993-11-12. PMID:8080477. |
to determine if the apparent greater efficacy of ngf compared to bdnf might be related to differences in delivery, we examined the patterns of distribution of radiolabeled bdnf and ngf injected into the lateral ventricle. |
1993-11-12 |
2023-08-12 |
rat |
| D Hoffman, X O Breakefield, M P Short, P Aebische. Transplantation of a polymer-encapsulated cell line genetically engineered to release NGF. Experimental neurology. vol 122. issue 1. 1993-09-02. PMID:8339781. |
the delivery of nerve growth factor (ngf) to the lateral ventricle of a fimbria-fornix-lesioned rat prevents the lesion-induced reduction in choline acetyltransferase (chat) expression by medial septal cells. |
1993-09-02 |
2023-08-12 |
rat |
| A C Santucci, P D Kanof, V Haroutunia. Cholinergic marker deficits induced by lesions of the nucleus basalis of Meynert are attenuated by nerve growth factor in young, but not in aged, F344 rats. Brain research. vol 609. issue 1-2. 1993-07-15. PMID:8508314. |
to investigate the efficacy of nerve growth factor (ngf) in promoting recovery from cholinergic damage, young (3-4 month old) and aged (22-23 month old) fischer 344 rats received nmda-induced unilateral lesions of the nucleus basalis of meynert and subcutaneous osmotic pumps (2-week duration) connected to permanently implanted cannulas directed at the lateral ventricle ipsilateral to the lesion. |
1993-07-15 |
2023-08-12 |
human |
| H R Widmer, B Knüsel, F Heft. BDNF protection of basal forebrain cholinergic neurons after axotomy: complete protection of p75NGFR-positive cells. Neuroreport. vol 4. issue 4. 1993-07-01. PMID:8499589. |
to elucidate the role of brain derived neurotrophic factor (bdnf) in the protection of cholinergic neurons in the basal forebrain, recombinant human bdnf and as a positive control, human recombinant nerve growth factor (ngf), were infused for 20 days into the lateral ventricle of adult rats with fimbrial transections. |
1993-07-01 |
2023-08-12 |
human |
| T Hagg, S Varo. Neurotropism of nerve growth factor for adult rat septal cholinergic axons in vivo. Experimental neurology. vol 119. issue 1. 1993-03-15. PMID:8432350. |
a 4-week infusion with ngf into the rostral portion of the lateral ventricle induced sprouting of cholinergic fibers in the dorsolateral septum with a gradient toward the lateral ventricle. |
1993-03-15 |
2023-08-12 |
rat |
| T Hagg, S Varo. Neurotropism of nerve growth factor for adult rat septal cholinergic axons in vivo. Experimental neurology. vol 119. issue 1. 1993-03-15. PMID:8432350. |
(iii) when animals with a unilateral fimbria-fornix transection (but no nerve graft) were infused with ngf into the lateral ventricle on the opposite side, cholinergic sprouting was oriented toward the midline of the septum. |
1993-03-15 |
2023-08-12 |
rat |
| L G Isaacson, B N Saffran, K A Crutche. Nerve growth factor-induced sprouting of mature, uninjured sympathetic axons. The Journal of comparative neurology. vol 326. issue 3. 1993-01-27. PMID:1469116. |
the infusion of nerve growth factor (ngf) into the lateral ventricle of the mature rat brain elicits a sprouting response from axons associated with the intradural segment of the internal carotid artery. |
1993-01-27 |
2023-08-11 |
rat |
| A J Dekker, L J Tha. Effect of delayed treatment with nerve growth factor on choline acetyltransferase activity in the cortex of rats with lesions of the nucleus basalis magnocellularis: dose requirements. Brain research. vol 584. issue 1-2. 1992-10-07. PMID:1515953. |
starting two weeks after the lesion, cytochrome c (0.3 micrograms/rat/day) or 0.01, 0.1, 1 or 10 micrograms/rat/day human recombinant nerve growth factor (ngf) was infused into the lateral ventricle. |
1992-10-07 |
2023-08-11 |
human |
| T Hagg, D Quon, J Higaki, S Varo. Ciliary neurotrophic factor prevents neuronal degeneration and promotes low affinity NGF receptor expression in the adult rat CNS. Neuron. vol 8. issue 1. 1992-02-20. PMID:1309648. |
recombinant human ciliary neurotrophic factor (cntf) was infused for 2 weeks into the lateral ventricle of fimbria-fornix transected adult rats, and its effects were compared with those of purified mouse nerve growth factor (ngf). |
1992-02-20 |
2023-08-11 |
mouse |
| A J Dekker, D J Langdon, F H Gage, L J Tha. NGF increases cortical acetylcholine release in rats with lesions of the nucleus basalis. Neuroreport. vol 2. issue 10. 1992-02-04. PMID:1756238. |
two weeks after the lesion, osmotic minipumps were implanted, that infused 1 microgram human recombinant nerve growth factor (ngf) or cytochrome-c per day into the lateral ventricle. |
1992-02-04 |
2023-08-11 |
human |
| G Nisticò, M R Ciriolo, K Fiskin, M Iannone, A De Martino, G Rotili. NGF restores decrease in catalase and increases glutathione peroxidase activity in the brain of aged rats. Neuroscience letters. vol 130. issue 1. 1992-01-21. PMID:1749511. |
the effects of subchronic administration of nerve growth factor (ngf) into the lateral ventricle on catalase and selenium-dependent glutathione-peroxidase (gsh-px) activity in several areas of the brain in 3-, 12- and 24-month-old rats were studied. |
1992-01-21 |
2023-08-11 |
rat |
| G Nisticò, M R Ciriolo, K Fiskin, M Iannone, A De Martino, G Rotili. NGF restores decrease in catalase and increases glutathione peroxidase activity in the brain of aged rats. Neuroscience letters. vol 130. issue 1. 1992-01-21. PMID:1749511. |
in conclusion, the present results show that long-term administration of ngf into the lateral ventricle significantly increases in old animals the activity of key enzymes involved in the metabolic degradation of hydrogen peroxide. |
1992-01-21 |
2023-08-11 |
rat |
| W Fischer, A Björklund, K Chen, F H Gag. NGF improves spatial memory in aged rodents as a function of age. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 11. issue 7. 1991-08-12. PMID:1648601. |
the aged impaired rats were retested twice during ngf or vehicle infusion in the right lateral ventricle. |
1991-08-12 |
2023-08-11 |
rat |