| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Y Lai, J R Clements, J M Siege. Glutamatergic and cholinergic projections to the pontine inhibitory area identified with horseradish peroxidase retrograde transport and immunohistochemistry. The Journal of comparative neurology. vol 336. issue 3. 1994-01-27. PMID:7505295. |
dense retrograde wga-hrp labelling was found in neurons in the periaqueductal gray (pag) and mesencephalic reticular formation (mrf) at the red nucleus (rn) level, ventral portion of paralemniscal tegmental field (vftp), retrorubral nucleus (rrn), contralateral side of pia (cpia), pontis reticularis centralis caudalis (poc), and most rostral portion of the nucleus parvicellularis (npv) and nucleus praepositus hypoglossi (ph) at the level of the pontomedullary junction; moderate labelling was seen in pedunculopontine nucleus, pars compacta (ppnc), laterodorsal tegmental nucleus (ldt), superior colliculus (sc), mrf and pag at the level caudal to rn, medial and superior vestibular nuclei, and principle sensory trigeminal nucleus (5p); and light labelling was seen in dorsal raphe (dr) and locus coeruleus complex (lcc). |
1994-01-27 |
2023-08-12 |
Not clear |
| S Higo, J Kawano, T Matsuyama, S Kawamur. Differential projections to the superior collicular layers from the perihypoglossal nuclei in the cat. Brain research. vol 599. issue 1. 1993-03-05. PMID:1283562. |
injections of the tracer into the superficial layers of the sc yielded retrogradely labeled cells only in the rostral part of the contralateral int; by contrast, the injection confined to the deep layers produced labeling of cells exclusively in the nucleus prepositus hypoglossi (ph). |
1993-03-05 |
2023-08-11 |
cat |
| N Lad, A C Honey, D O Lunt, R F Booth, J Westwick, P W Manley, D P Tuffi. Effect of SC 38249, a novel substituted imidazole, on platelet aggregation in vitro and in vivo. Thrombosis and haemostasis. vol 59. issue 2. 1988-07-29. PMID:3133807. |
although less potent, sc 38249 retained significant inhibitory activity against prp responses induced by a higher (3.0 micrograms ml-1) concentration of collagen (ic50: 272.5 +/- 24.6 microm), and against paf-acether-induced responses in prp pre-treated with 10 microm indomethacin (i.c.50: 192.0 +/- 16.1 microm). |
1988-07-29 |
2023-08-11 |
human |
| N Lad, A C Honey, D O Lunt, R F Booth, J Westwick, P W Manley, D P Tuffi. Effect of SC 38249, a novel substituted imidazole, on platelet aggregation in vitro and in vivo. Thrombosis and haemostasis. vol 59. issue 2. 1988-07-29. PMID:3133807. |
experimental animal studies confirmed the in vitro anti-aggregatory efficacy of sc 38249, since significant inhibitory activity was observed against paf-acether and adp-induced responses in dog prp ex vivo, anti-forssman antibody-induced thrombocytopenia in anaesthetized guinea pigs, and collagen-induced intravascular aggregation in anaesthetized rabbits. |
1988-07-29 |
2023-08-11 |
human |
| R Gabizon, M P McKinley, D F Groth, L Kenaga, S B Prusine. Properties of scrapie prion protein liposomes. The Journal of biological chemistry. vol 263. issue 10. 1988-05-02. PMID:3350818. |
prp 27-30 is derived by limited proteolysis from a larger protein designated prp(sc) which is membrane bound. |
1988-05-02 |
2023-08-11 |
Not clear |
| R Gabizon, M P McKinley, D F Groth, L Kenaga, S B Prusine. Properties of scrapie prion protein liposomes. The Journal of biological chemistry. vol 263. issue 10. 1988-05-02. PMID:3350818. |
prp(sc) in membrane fractions was solubilized by incorporation in dlpc, thus preventing its aggregation into amyloid rods. |
1988-05-02 |
2023-08-11 |
Not clear |