| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P J Lefebvre, A S Luyck. Neurotransmitters and glucagon release from the isolated, perfused canine stomach. Diabetes. vol 29. issue 9. 1981-02-26. PMID:7439545. |
the isolated, perfused, canine stomach was used to investigate the effect of three neurotransmitters--norepinephrine, acetylcholine (or its analogue carbamylcholine), and vip (vasoactive intestinal peptide)--on gastric glucagon release. |
1981-02-26 |
2023-08-12 |
dog |
| P J Lefebvre, A S Luyck. Neurotransmitters and glucagon release from the isolated, perfused canine stomach. Diabetes. vol 29. issue 9. 1981-02-26. PMID:7439545. |
in contrast, acetylcholine or carbamylcholine (5.10-6 m) as well as vip (46-60 ng/ml) unequivocally stimulated gastric glucagon release, an effect apparently independent of the changes in blood flow. |
1981-02-26 |
2023-08-12 |
dog |
| T Hökfelt, J M Lundberg, M Schultzberg, O Johansson, L Skirboll, A Anggård, B Fredholm, B Hamberger, B Pernow, J Rehfeld, M Goldstei. Cellular localization of peptides in neural structures. Proceedings of the Royal Society of London. Series B, Biological sciences. vol 210. issue 1178. 1981-01-26. PMID:6159653. |
in the former system vip seems to be responsible mainly for vasodilation, whereas acetylcholine mainly causes secretion. |
1981-01-26 |
2023-08-12 |
cat |
| D D Heistad, M L Marcus, S I Said, P M Gros. Effect of acetylcholine and vasoactive intestinal peptide on cerebral blood flow. The American journal of physiology. vol 239. issue 1. 1980-09-28. PMID:7396021. |
effect of acetylcholine and vasoactive intestinal peptide on cerebral blood flow. |
1980-09-28 |
2023-08-12 |
Not clear |
| D D Heistad, M L Marcus, S I Said, P M Gros. Effect of acetylcholine and vasoactive intestinal peptide on cerebral blood flow. The American journal of physiology. vol 239. issue 1. 1980-09-28. PMID:7396021. |
these experiments were performed to determine whether the neurotransmitters acetylcholine (ach) and vasoactive intestinal peptide (vip) increase cerebral blood flow (cbf). |
1980-09-28 |
2023-08-12 |
Not clear |
| J M Lundberg, A Anggård, J Fahrenkrug, T Hökfelt, V Mut. Vasoactive intestinal polypeptide in cholinergic neurons of exocrine glands: functional significance of coexisting transmitters for vasodilation and secretion. Proceedings of the National Academy of Sciences of the United States of America. vol 77. issue 3. 1980-07-22. PMID:6103537. |
by a combination of the indirect immunofluorescence technique with acetylcholinesterase (acetylcholine acetylhydrolase, ec 3.1.1.7) staining, it was shown that vasoactive intestinal polypeptide (vip) is present in cholinergic (acetylcholinesterase-rich) neurons involved in control of secretion and vasodilation in exocrine glands of cat. |
1980-07-22 |
2023-08-12 |
cat |
| J M Lundberg, A Anggård, J Fahrenkrug, T Hökfelt, V Mut. Vasoactive intestinal polypeptide in cholinergic neurons of exocrine glands: functional significance of coexisting transmitters for vasodilation and secretion. Proceedings of the National Academy of Sciences of the United States of America. vol 77. issue 3. 1980-07-22. PMID:6103537. |
infusion of vip caused vasodilation only, whereas acetylcholine caused both vasodilation and secretion. |
1980-07-22 |
2023-08-12 |
cat |
| J M Lundberg, A Anggård, J Fahrenkrug, T Hökfelt, V Mut. Vasoactive intestinal polypeptide in cholinergic neurons of exocrine glands: functional significance of coexisting transmitters for vasodilation and secretion. Proceedings of the National Academy of Sciences of the United States of America. vol 77. issue 3. 1980-07-22. PMID:6103537. |
simultaneous infusion of vip and acetylcholine in low doses resulted in a marked potentiation of both vasodilation and secretion. |
1980-07-22 |
2023-08-12 |
cat |
| J M Lundberg, A Anggård, J Fahrenkrug, T Hökfelt, V Mut. Vasoactive intestinal polypeptide in cholinergic neurons of exocrine glands: functional significance of coexisting transmitters for vasodilation and secretion. Proceedings of the National Academy of Sciences of the United States of America. vol 77. issue 3. 1980-07-22. PMID:6103537. |
preganglionic cholinergic nerves activate, via nicotinic receptors, postganglionic neurons, causing concomitant release from the same nerve endings of two coexisting putative transmitters, acetylcholine and vip. |
1980-07-22 |
2023-08-12 |
cat |
| J M Lundberg, A Anggård, J Fahrenkrug, T Hökfelt, V Mut. Vasoactive intestinal polypeptide in cholinergic neurons of exocrine glands: functional significance of coexisting transmitters for vasodilation and secretion. Proceedings of the National Academy of Sciences of the United States of America. vol 77. issue 3. 1980-07-22. PMID:6103537. |
acetylcholine produces mainly secretion by a muscarinic action and vip causes mainly vasodilation, but the two substances seem to cooperate directly or indirectly in both types of response. |
1980-07-22 |
2023-08-12 |
cat |
| J M Lundberg, A Anggård, J Fahrenkrug, T Hökfelt, V Mut. Vasoactive intestinal polypeptide in cholinergic neurons of exocrine glands: functional significance of coexisting transmitters for vasodilation and secretion. Proceedings of the National Academy of Sciences of the United States of America. vol 77. issue 3. 1980-07-22. PMID:6103537. |
thus, the coexistence of two putative neurotransmitters, vip and acetylcholine, in one neuron may explain the dual effector response (i.e., the cholinergic secretion and the atropine-resistant vasodilation) caused by nerve stimulation in exocrine glands. |
1980-07-22 |
2023-08-12 |
cat |
| T Shimizu, N Tair. Assessment of the effects of vasoactive intestinal peptide (VIP) on blood flow through and salivation of the dog salivary gland in comparison with those of secretin, glucagon and acetylcholine. British journal of pharmacology. vol 65. issue 4. 1979-07-25. PMID:435691. |
assessment of the effects of vasoactive intestinal peptide (vip) on blood flow through and salivation of the dog salivary gland in comparison with those of secretin, glucagon and acetylcholine. |
1979-07-25 |
2023-08-11 |
dog |
| T Shimizu, N Tair. Assessment of the effects of vasoactive intestinal peptide (VIP) on blood flow through and salivation of the dog salivary gland in comparison with those of secretin, glucagon and acetylcholine. British journal of pharmacology. vol 65. issue 4. 1979-07-25. PMID:435691. |
vasoactive intestinal peptide (vip), secretin and acetylcholine produced a dose-dependent increase in blood flow through the artery (vasodilatation) but glucagon was almost ineffective. |
1979-07-25 |
2023-08-11 |
dog |
| T Shimizu, N Tair. Assessment of the effects of vasoactive intestinal peptide (VIP) on blood flow through and salivation of the dog salivary gland in comparison with those of secretin, glucagon and acetylcholine. British journal of pharmacology. vol 65. issue 4. 1979-07-25. PMID:435691. |
dose-blood flow response curves for acetylcholine were flatter than those for vip and secretin. |
1979-07-25 |
2023-08-11 |
dog |
| T Shimizu, N Tair. Assessment of the effects of vasoactive intestinal peptide (VIP) on blood flow through and salivation of the dog salivary gland in comparison with those of secretin, glucagon and acetylcholine. British journal of pharmacology. vol 65. issue 4. 1979-07-25. PMID:435691. |
the vasodilator responses to vip and to electrical stimulation of the chordolingual nerve were scarcely modified by (-)-hyoscyamine in doses that fully antagonized the vasodilator response to acetylcholine. |
1979-07-25 |
2023-08-11 |
dog |
| K G Morgan, P F Schmalz, J H Szurszewsk. The inhibitory effects of vasoactive intestinal polypeptide on the mechanical and electrical activity of canine antral smooth muscle. The Journal of physiology. vol 282. 1979-02-26. PMID:722548. |
vip had no effect on the increase in the amplitude and duration of the plateau potential and on the amplitude of contraction caused by a maximally effective concentration of acetylcholine. |
1979-02-26 |
2023-08-11 |
Not clear |
| K G Morgan, P F Schmalz, J H Szurszewsk. The inhibitory effects of vasoactive intestinal polypeptide on the mechanical and electrical activity of canine antral smooth muscle. The Journal of physiology. vol 282. 1979-02-26. PMID:722548. |
vip caused a significant decrease in the force of contraction caused by ed50 and threshold concentrations of acetylcholine. |
1979-02-26 |
2023-08-11 |
Not clear |
| K G Morgan, P F Schmalz, J H Szurszewsk. The inhibitory effects of vasoactive intestinal polypeptide on the mechanical and electrical activity of canine antral smooth muscle. The Journal of physiology. vol 282. 1979-02-26. PMID:722548. |
however, vip had no measurable effect on the increase in the size of the action potential plateau caused by either concentration of acetylcholine. |
1979-02-26 |
2023-08-11 |
Not clear |