| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eyal Y Kimchi, Anthony Burgos-Robles, Gillian A Matthews, Tatenda Chakoma, Makenzie Patarino, Javier C Weddington, Cody Siciliano, Wannan Yang, Shaun Foutch, Renee Simons, Ming-Fai Fong, Miao Jing, Yulong Li, Daniel B Polley, Kay M Ty. Reward contingency gates selective cholinergic suppression of amygdala neurons. eLife. vol 12. 2024-02-20. PMID:38376907. |
photostimulation of basal forebrain cholinergic neurons, or their terminals in the basolateral amygdala (bla), selectively promoted conditioned responding (licking), but not unconditioned behavior nor innate motor outputs. |
2024-02-20 |
2024-02-22 |
Not clear |
| Eyal Y Kimchi, Anthony Burgos-Robles, Gillian A Matthews, Tatenda Chakoma, Makenzie Patarino, Javier C Weddington, Cody Siciliano, Wannan Yang, Shaun Foutch, Renee Simons, Ming-Fai Fong, Miao Jing, Yulong Li, Daniel B Polley, Kay M Ty. Reward contingency gates selective cholinergic suppression of amygdala neurons. eLife. vol 12. 2024-02-20. PMID:38376907. |
taken together, we show that the neural and behavioral effects of basal forebrain cholinergic activation are modulated by reward contingency in a target-specific manner. |
2024-02-20 |
2024-02-22 |
Not clear |
| Prithviraj Rajebhosale, Mala R Ananth, Ronald Kim, Richard B Crouse, Li Jiang, Gretchen López-Hernández, Chongbo Zhong, Christian Arty, Shaohua Wang, Alice Jone, Niraj S Desai, Yulong Li, Marina R Picciotto, Lorna W Role, David A Talmag. Functionally refined encoding of threat memory by distinct populations of basal forebrain cholinergic projection neurons. eLife. vol 13. 2024-02-16. PMID:38363713. |
functionally refined encoding of threat memory by distinct populations of basal forebrain cholinergic projection neurons. |
2024-02-16 |
2024-02-19 |
Not clear |
| Scott G Knudstrup, Catalina Martinez, Bradley C Rauscher, Patrick R Doran, Natalie Fomin-Thunemann, Kivilcim Kilic, John Jiang, Anna Devor, Martin Thunemann, Jeffrey P Gavorni. Visual stimulation drives retinotopic acetylcholine release in the mouse visual cortex. bioRxiv : the preprint server for biology. 2024-02-14. PMID:38352456. |
the spatiotemporal characteristics of neocortical acetylcholine (ach) release in response to sensory inputs are poorly understood, but a lack of intra-region topographic organization of cholinergic projections from the basal forebrain has suggested diffuse release patterns and volume transmission. |
2024-02-14 |
2024-02-16 |
mouse |
| Dayan Knox, Vinay Parik. Basal forebrain cholinergic systems as circuits through which traumatic stress disrupts emotional memory regulation. Neuroscience and biobehavioral reviews. 2024-02-03. PMID:38309497. |
basal forebrain cholinergic systems as circuits through which traumatic stress disrupts emotional memory regulation. |
2024-02-03 |
2024-02-06 |
Not clear |
| Dayan Knox, Vinay Parik. Basal forebrain cholinergic systems as circuits through which traumatic stress disrupts emotional memory regulation. Neuroscience and biobehavioral reviews. 2024-02-03. PMID:38309497. |
cholinergic basal forebrain (chbf) neurons provide input to contextual/spatial systems and although chbf neurons are important for emotional memory, it is unknown how they contribute to the traumatic stress effects on emotional memory. |
2024-02-03 |
2024-02-06 |
Not clear |
| Anders Björklund, Roger A Barke. The basal forebrain cholinergic system as target for cell replacement therapy in Parkinson's disease. Brain : a journal of neurology. 2024-01-27. PMID:38279949. |
the basal forebrain cholinergic system as target for cell replacement therapy in parkinson's disease. |
2024-01-27 |
2024-01-30 |
human |
| Anders Björklund, Roger A Barke. The basal forebrain cholinergic system as target for cell replacement therapy in Parkinson's disease. Brain : a journal of neurology. 2024-01-27. PMID:38279949. |
in recent years there has been a renewed interest in the basal forebrain (bf) cholinergic system as a target for the treatment of cognitive impairments in patients with parkinson´s disease (pd), due in part to the need to explore novel approaches to treat the cognitive symptoms of the disease, and in part to the development of more refined imaging tools that have made it possible to monitor the progressive changes in the structure and function of the bf system as they evolve over time. |
2024-01-27 |
2024-01-30 |
human |
| Andrew Speidell, Christy Agbey, Italo Mocchett. Accelerated neurodegeneration of basal forebrain cholinergic neurons in HIV-1 gp120 transgenic mice: Critical role of the p75 neurotrophin receptor. Brain, behavior, and immunity. 2024-01-24. PMID:38266662. |
accelerated neurodegeneration of basal forebrain cholinergic neurons in hiv-1 gp120 transgenic mice: critical role of the p75 neurotrophin receptor. |
2024-01-24 |
2024-01-27 |
mouse |
| Ruben Carvalho, Alisa N Lukoyanova, João Casalta-Lopes, Nikolay V Lukoyanov, Joana Isabel Soare. Plastic rearrangement of basal forebrain parvalbumin-immunoreactive neurons in the kainite model of epilepsy. AIMS neuroscience. vol 10. issue 4. 2024-01-08. PMID:38188006. |
in addition to the temporal lobe structures, it was found that the basal forebrain cholinergic cells are also involved in epileptogenesis. |
2024-01-08 |
2024-01-10 |
rat |
| Andrew A George, Sabin J John, Linda M Lucero, J Brek Eaton, Ekta Jaiswal, Sean B Christensen, Joanna Gajewiak, Maren Watkins, Yiwei Cao, Baldomero M Olivera, Wonpil Im, J Michael McIntosh, Paul Whiteake. Analogs of α-conotoxin PnIC selectively inhibit α7β2- over α7-only subtype nicotinic acetylcholine receptors via a novel allosteric mechanism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 38. issue 1. 2024-01-01. PMID:38161283. |
basal forebrain cholinergic neurons express α7β2-nachr. |
2024-01-01 |
2024-01-05 |
Not clear |
| Juliet Bottorff, Sydney Padgett, Gina G Turrigian. Basal forebrain cholinergic activity is necessary for upward firing rate homeostasis in the rodent visual cortex. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 1. 2023-12-26. PMID:38147559. |
basal forebrain cholinergic activity is necessary for upward firing rate homeostasis in the rodent visual cortex. |
2023-12-26 |
2023-12-29 |
rat |
| Juliet Bottorff, Sydney Padgett, Gina G Turrigian. Basal forebrain cholinergic activity is necessary for upward firing rate homeostasis in the rodent visual cortex. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 1. 2023-12-26. PMID:38147559. |
a major difference between quiet wake (qw), when upward frh is absent, and aw, when it is present, is increased cholinergic (ach) tone, and the main cholinergic projections to v1 arise from the horizontal diagonal band of the basal forebrain (hdb ach). |
2023-12-26 |
2023-12-29 |
rat |
| Samual J Crowley, Prabesh Kanel, Stiven Roytman, Nicolaas I Bohnen, Benjamin M Hampstea. Basal forebrain integrity, cholinergic innervation and cognition in idiopathic Parkinson's disease. Brain : a journal of neurology. 2023-12-18. PMID:38109781. |
basal forebrain integrity, cholinergic innervation and cognition in idiopathic parkinson's disease. |
2023-12-18 |
2023-12-21 |
Not clear |
| Samual J Crowley, Prabesh Kanel, Stiven Roytman, Nicolaas I Bohnen, Benjamin M Hampstea. Basal forebrain integrity, cholinergic innervation and cognition in idiopathic Parkinson's disease. Brain : a journal of neurology. 2023-12-18. PMID:38109781. |
mounting evidence suggests this is partially caused by cholinergic denervation due to α-synuclein pathology in the cholinergic basal forebrain. |
2023-12-18 |
2023-12-21 |
Not clear |
| Samual J Crowley, Prabesh Kanel, Stiven Roytman, Nicolaas I Bohnen, Benjamin M Hampstea. Basal forebrain integrity, cholinergic innervation and cognition in idiopathic Parkinson's disease. Brain : a journal of neurology. 2023-12-18. PMID:38109781. |
prior studies have shown an association between basal forebrain integrity and cognition, cholinergic levels and cognition, and basal forebrain volume and acetylcholine, but no study has directly investigated whether basal forebrain physiology mediates the relationship between acetylcholine and cognition in parkinson's disease. |
2023-12-18 |
2023-12-21 |
Not clear |
| Samual J Crowley, Prabesh Kanel, Stiven Roytman, Nicolaas I Bohnen, Benjamin M Hampstea. Basal forebrain integrity, cholinergic innervation and cognition in idiopathic Parkinson's disease. Brain : a journal of neurology. 2023-12-18. PMID:38109781. |
data were entered into parallel mediation analyses with the cholinergic projection areas as predictors, cholinergic basal forebrain volume and free water fraction as mediators, and each cognitive domain as outcomes. |
2023-12-18 |
2023-12-21 |
Not clear |
| Samual J Crowley, Prabesh Kanel, Stiven Roytman, Nicolaas I Bohnen, Benjamin M Hampstea. Basal forebrain integrity, cholinergic innervation and cognition in idiopathic Parkinson's disease. Brain : a journal of neurology. 2023-12-18. PMID:38109781. |
free water fraction in the cholinergic basal forebrain mediates the relationship between acetylcholine and attention/working memory and executive function, while cholinergic basal forebrain volume mediated the relationship between acetylcholine in temporal regions in memory. |
2023-12-18 |
2023-12-21 |
Not clear |
| Bing Li, Chenyan Ma, Yun-An Huang, Xinlu Ding, Daniel Silverman, Changwan Chen, Dana Darmohray, Lihui Lu, Siqi Liu, Gabriel Montaldo, Alan Urban, Yang Da. Circuit mechanism for suppression of frontal cortical ignition during NREM sleep. Cell. 2023-12-09. PMID:38070510. |
chemogenetic activation and inactivation of basal forebrain cholinergic neurons powerfully increased and decreased visual-to-frontal activity propagation, respectively. |
2023-12-09 |
2023-12-17 |
mouse |
| Jarrod A Gott, Sina Stücker, Philipp Kanske, Jan Haaker, Martin Dresle. Acetylcholine and metacognition during sleep. Consciousness and cognition. vol 117. 2023-12-02. PMID:38042119. |
additionally, acetylcholine is involved in the regulation of rem sleep: cholinergic neurons in the brainstem and basal forebrain project to and innervate wide areas of the cerebral cortex, and reciprocally interact with other neuromodulatory systems, to produce the sleep-wake cycle and different sleep stages. |
2023-12-02 |
2023-12-10 |
Not clear |