Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Y Naito, S Kuzuhar. [Parkinsonism induced or worsened by cisapride]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics. vol 31. issue 11. 1995-05-24. PMID:7723193. |
experimental studies have revealed that it has indirect cholinomimetic effects and potentially stimulates the gastrointestinal motor activity without blocking dopamine receptors or activating muscarinic cholinergic receptors. |
1995-05-24 |
2023-08-12 |
Not clear |
C A Willson, J Luthman, B Hoffer, I Hani. The use of the rat iris as a model system to evaluate the effect of the cholinotoxin, AF64A, in vivo. Journal of neuroscience methods. vol 56. issue 1. 1995-05-16. PMID:7715246. |
af64a is selective for cholinergic neurons, since norepinephrine and dopamine levels were unaffected. |
1995-05-16 |
2023-08-12 |
rat |
G N Kryzhanovskii, M A Atadzhanov, T A Voronina, L N Nerobkov. Features of the parkinsonian syndrome induced experimentally by a deficit of nigrostriatal dopamine and stimulation of cholinergic neurons of the caudate nuclei. Neuroscience and behavioral physiology. vol 24. issue 6. 1995-05-16. PMID:7715769. |
features of the parkinsonian syndrome induced experimentally by a deficit of nigrostriatal dopamine and stimulation of cholinergic neurons of the caudate nuclei. |
1995-05-16 |
2023-08-12 |
Not clear |
G M Peterso. Sprouting of central noradrenergic fibers in the dentate gyrus following combined lesions of its entorhinal and septal afferents. Hippocampus. vol 4. issue 6. 1995-05-10. PMID:7704108. |
the noradrenergic identity of the fibers was indicated by immunoreactivity for dopamine beta hydroxylase (dbh) and peripheral sympathetic fibers were demonstrated by immunoreactivity for nerve growth factor receptor (ngfr), which did not stain cholinergic fibers in this application. |
1995-05-10 |
2023-08-12 |
rat |
A L Jongen-Rêlo, G J Docter, A J Jonker, P Voor. Differential localization of mRNAs encoding dopamine D1 or D2 receptors in cholinergic neurons in the core and shell of the rat nucleus accumbens. Brain research. Molecular brain research. vol 28. issue 1. 1995-05-10. PMID:7707872. |
differential localization of mrnas encoding dopamine d1 or d2 receptors in cholinergic neurons in the core and shell of the rat nucleus accumbens. |
1995-05-10 |
2023-08-12 |
rat |
M Kudernatsch, B Suto. Cholinergic modulation of dopamine overflow in the rat neostriatum: a fast cyclic voltammetric study in vitro. Neuroscience letters. vol 181. issue 1-2. 1995-04-27. PMID:7898747. |
cholinergic modulation of dopamine overflow in the rat neostriatum: a fast cyclic voltammetric study in vitro. |
1995-04-27 |
2023-08-12 |
rat |
R M Ridley, H F Baker, L E Annett, S B Dunnett, E M Torres, A Fin. Behavioral assessment of the ability of intracerebral embryonic neural tissue grafts to ameliorate the effects of brain damage in marmosets. Molecular neurobiology. vol 9. issue 1-3. 1995-04-18. PMID:7888097. |
in this context, a small number of transplant experiments have been carried out in monkeys with lesions of the central dopamine and cholinergic systems. |
1995-04-18 |
2023-08-12 |
rat |
A Zocchi, A Per. Alterations in striatal acetylcholine overflow by cocaine, morphine, and MK-801: relationship to locomotor output. Psychopharmacology. vol 115. issue 3. 1995-03-24. PMID:7871068. |
the activity of cholinergic interneurons in the striatum appears to be modulated by a variety of different systems including dopamine, opiate, and glutamate. |
1995-03-24 |
2023-08-12 |
Not clear |
G Chouinard, J L Vainer, M C Bélanger, L Turnier, P Beaudry, J Y Roy, R Mille. Risperidone and clozapine in the treatment of drug-resistant schizophrenia and neuroleptic-induced supersensitivity psychosis. Progress in neuro-psychopharmacology & biological psychiatry. vol 18. issue 7. 1995-03-07. PMID:7531355. |
thus, the drug-induced parkinsonism, which was proposed as mediating the antipsychotic effect of dopamine d2 blocking drugs, depends on the integrity of these cholinergic neurons. |
1995-03-07 |
2023-08-12 |
Not clear |
J C Day, C S Tham, H C Fibige. Dopamine depletion attenuates amphetamine-induced increases of cortical acetylcholine release. European journal of pharmacology. vol 263. issue 3. 1995-03-03. PMID:7843266. |
these results point to an important role for forebrain dopamine in the regulation of cortically projecting cholinergic neurons and fail to support the hypothesis that the ascending noradrenergic projections of the locus coeruleus are significantly involved. |
1995-03-03 |
2023-08-12 |
rat |
A Imperato, M C Obinu, G Carta, M S Mascia, M A Casu, L Dazzi, G L Gess. Neuroleptics cause stimulation of dopamine D1 receptors and their desensitization after chronic treatment. European journal of pharmacology. vol 264. issue 1. 1995-02-23. PMID:7828643. |
recent evidence indicates that the neuroleptic-induced increase of in vivo acetylcholine output in the striatum does not depend on the relief of cholinergic neurons from the inhibitory control by dopamine, but on increased dopamine output onto dopamine d1 receptors. |
1995-02-23 |
2023-08-12 |
rat |
S Hernández-López, J L Góngora-Alfaro, D Martínez-Fong, M G Rosales, J Aceve. Cholinergic stimulation of rostral and caudal substantia nigra pars compacta produces opposite effects on circling behavior and striatal dopamine release measured by brain microdialysis. Neuroscience. vol 62. issue 2. 1995-02-17. PMID:7830890. |
cholinergic stimulation of rostral and caudal substantia nigra pars compacta produces opposite effects on circling behavior and striatal dopamine release measured by brain microdialysis. |
1995-02-17 |
2023-08-12 |
rat |
S Hernández-López, J L Góngora-Alfaro, D Martínez-Fong, M G Rosales, J Aceve. Cholinergic stimulation of rostral and caudal substantia nigra pars compacta produces opposite effects on circling behavior and striatal dopamine release measured by brain microdialysis. Neuroscience. vol 62. issue 2. 1995-02-17. PMID:7830890. |
recent studies have shown that microinjection of cholinergic agonists into the substantia nigra pars compacta increases dopamine release and turnover in the striatum of anesthetized rats [hernández-lópez et al. |
1995-02-17 |
2023-08-12 |
rat |
S Hernández-López, J L Góngora-Alfaro, D Martínez-Fong, M G Rosales, J Aceve. Cholinergic stimulation of rostral and caudal substantia nigra pars compacta produces opposite effects on circling behavior and striatal dopamine release measured by brain microdialysis. Neuroscience. vol 62. issue 2. 1995-02-17. PMID:7830890. |
in this study, the relationship between circling behavior and striatal dopamine release following cholinergic stimulation of the substantia nigra pars compacta neurons was assessed by brain microdialysis in awake rats. |
1995-02-17 |
2023-08-12 |
rat |
S Hernández-López, J L Góngora-Alfaro, D Martínez-Fong, M G Rosales, J Aceve. Cholinergic stimulation of rostral and caudal substantia nigra pars compacta produces opposite effects on circling behavior and striatal dopamine release measured by brain microdialysis. Neuroscience. vol 62. issue 2. 1995-02-17. PMID:7830890. |
the results indicate that cholinergic stimulation of the substantia nigra pars compacta with the mixed nicotinic-muscarinic cholinergic agonist carbachol modulates striatal dopamine release, and this effect is accompanied by circling behavior and stereotypies. |
1995-02-17 |
2023-08-12 |
rat |
S Hernández-López, J L Góngora-Alfaro, D Martínez-Fong, M G Rosales, J Aceve. Cholinergic stimulation of rostral and caudal substantia nigra pars compacta produces opposite effects on circling behavior and striatal dopamine release measured by brain microdialysis. Neuroscience. vol 62. issue 2. 1995-02-17. PMID:7830890. |
we conclude that the cholinergic input to the substantia nigra pars compacta could modulate the motor behavior through regulating the firing rate of nigrostriatal dopaminergic neurons and dopamine release in the neostriatum. |
1995-02-17 |
2023-08-12 |
rat |
M S Wainwright, B D Perry, L A Won, K L O'Malley, W Y Wang, M E Ehrlich, A Helle. Immortalized murine striatal neuronal cell lines expressing dopamine receptors and cholinergic properties. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 1 Pt 2. 1995-02-16. PMID:7823171. |
immortalized murine striatal neuronal cell lines expressing dopamine receptors and cholinergic properties. |
1995-02-16 |
2023-08-12 |
mouse |
A G Nasello, D Gidali, L C de Sá-Rocha, L F Felici. Differential effects of bromopride and domperidone on cholinesterase activity in rat tissues. Life sciences. vol 56. issue 3. 1995-02-16. PMID:7823770. |
these data suggest the existence of a cholinergic mechanism of action for these dopamine blocking agents. |
1995-02-16 |
2023-08-12 |
rat |
B J Vilner, B R de Costa, W D Bowe. Cytotoxic effects of sigma ligands: sigma receptor-mediated alterations in cellular morphology and viability. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 1 Pt 1. 1995-02-14. PMID:7823122. |
neuroleptics lacking potent sigma affinity [e.g., (-)-sulpiride, (+)-butaclamol, and clozapine] and other compounds that lack significant sigma affinity but that are agonists or antagonists at dopamine, serotonin, adrenergic, glutamate, phencyclidine, gaba, opiate, or muscarinic cholinergic receptors were without effect on cellular morphology at concentrations up to 300 microm over a period of 72 hr. |
1995-02-14 |
2023-08-12 |
Not clear |
J Kornhuber, M Welle. [Current status of biochemical hypotheses in the pathogenesis of schizophrenia]. Der Nervenarzt. vol 65. issue 11. 1995-02-09. PMID:7816150. |
the main focus of interest has shifted in recent years from the classical dopamine hypothesis to an increasing set of various neurotransmitter imbalance models of schizophrenic psychoses involving not only the dopaminergic system but also glutamatergic, serotonergic, cholinergic, gabaergic or peptidergic neuron systems. |
1995-02-09 |
2023-08-12 |
human |