| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Gerlac. Relationship between tardive dyskinesia, L-Dopa-induced hyperkinesia and parkinsonism. Psychopharmacology. vol 51. issue 3. 1977-05-20. PMID:403541. |
it is concluded that the irreversible neurotoxic effect of neuroleptic drugs may be associated with age-related changes in the oral somatotopic region of the basal ganglia (to be given consideration in any future search for the pathogenetic process underlying irreversible tardive dyskinesia), and that the pathophysiology of involuntary hyperkinesia in neuroleptic-treated psychiatric patients and in l-dopatreated parkinson patients may consist of a primary dopamine deficiency (pharmacological or structural), and a secondary relative hyperactivity in the dopaminergic system ("dopaminergic hypersensitivity") possibly corresponding to hypoactivity in the cholinergic system. |
1977-05-20 |
2023-08-11 |
Not clear |
| S Kaakkola, L Ahte. Effect of muscarinic cholinergic drugs on morphine-induced catalepsy, antinociception and changes in brain dopamine metabolism. Psychopharmacology. vol 52. issue 1. 1977-05-20. PMID:403561. |
effect of muscarinic cholinergic drugs on morphine-induced catalepsy, antinociception and changes in brain dopamine metabolism. |
1977-05-20 |
2023-08-11 |
rat |
| S Kaakkola, L Ahte. Effect of muscarinic cholinergic drugs on morphine-induced catalepsy, antinociception and changes in brain dopamine metabolism. Psychopharmacology. vol 52. issue 1. 1977-05-20. PMID:403561. |
the effects of drugs acting on muscarinic cholinergic receptors on the catalepsy, antinociception and changes in rectal temperature and in brain dopamine metabolism induced by morphine were studied in wistar rats. |
1977-05-20 |
2023-08-11 |
rat |
| A K Mukhopadhyay, N Weisbrod. Effect of dopamine on esophageal motor function. The American journal of physiology. vol 232. issue 1. 1977-03-15. PMID:835699. |
the effect of dopamine is not mediated via the vagal centers in the brain or cholinergic muscarinic and adrenergic receptors. |
1977-03-15 |
2023-08-11 |
Not clear |
| L L Butcher, L Bilezikjia. Acetylcholinesterase-containing neurons in the neostriatum and substantia nigra revealed after punctate intracerebral injection of di-isopropylfluorophosphate. European journal of pharmacology. vol 34. issue 1. 1977-02-24. PMID:1234757. |
although the significance of dopaminergic--cholinergic interactions in the neostriatum could not be elucidated on the basis of these histochemical data, the thesis was advanced that dopamine neurons in the pars compacta of the substantia nigra also contained ache, possibly to inactivate acetylcholine released from cholinergic fibers afferent to this neural structure. |
1977-02-24 |
2023-08-11 |
rat |
| N Tod. Influence of dopamine and noradrenaline on isolated cerebral arteries of the dog. British journal of pharmacology. vol 58. issue 1. 1977-01-03. PMID:974370. |
4 a mechanism other than beta-adrenergic, cholinergic or adenosine-related appears to be involved in the relaxation elicited by dopamine in cerebral arterial strips. |
1977-01-03 |
2023-08-11 |
dog |
| J P Tremblay, P B Woodson, W T Schlapfer, S H Baronde. Dopamine, serotonin and related compounds: presynaptic effects on synaptic depression, frequency facilitation, and post-tetanic potentiation at a synapse in Aplysia californica. Brain research. vol 109. issue 1. 1976-08-23. PMID:179667. |
dopamine, serotonin and related compounds (referred to collectively as biogenic amines) were found to modify transmission at the presumably cholinergic synapse made by an axon in the right visceropleural connective onto cell r15 of the abdominal ganglion of aplysia californica. |
1976-08-23 |
2023-08-11 |
aplysia |
| K Kataoka, M Sorimachi, S Okuno, N Mizun. Innervation of hypothalamic and limbic areas by the cholinergic, the GABA-ergic and the catecholaminergic nerve fibers; a quantitative analysis. Pharmacology, biochemistry, and behavior. vol 3. issue 1 Suppl. 1976-08-02. PMID:1226400. |
by measuring activities of enzymes involved in synthesis of acetylcholine, gamma-aminobutyric acid (gaba), dopamine or noradrenaline, extent of innervation of cholinergic, gaba-ergic, dopaminergic and noradrenergic fibers were analysed in discrete brain areas and subareas of the baboon and the rabbit with a special reference to the hypothalamus and the preoptic ares. |
1976-08-02 |
2023-08-11 |
rabbit |
| M Kanner, K Finnegan, H Y Meltze. Dopaminergic effects of phencyclidine in rats with nigrostriatal lesions. Psychopharmacology communications. vol 1. issue 4. 1976-07-06. PMID:1224008. |
these findings suggest that phencyclidine may be acting by increasing the availability of dopamine on the intact side of a unilaterally-lesioned substantia nigra rat and that the response can be modulated by alterations in the cholinergic system. |
1976-07-06 |
2023-08-11 |
rat |
| L Kh Allikmet. [The effect of adren- and serotoninergic substances on the behavior of amygdalectomized rats and on the aggressiveness evoked by intra-amygdaloid administration of acetylcholine]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 25. issue 1. 1976-03-05. PMID:1239875. |
the effect of serotoninergic (serotonin, 1-trytophane, imipramime, methysergide), catecholaminergic (noradrenaline, amphetamine, dopamine, 1-dopa, iproniazid) and cholinergic drugs (physostigmine, atropine, benactyzine) on emotional reactions and orienting-motor activity, as well as the effect of these drugs on shock-elicited aggressiveness enhanced by intraamygdaloid microinjection of acetylcholine was investigated in experiments on amygdalectomized male albino rats. |
1976-03-05 |
2023-08-11 |
rat |
| W Oelszner, K F Funk, I V Schwarzenfeld, A H Staib, K H Westerman. [Cholinergic effect on the dopamine turnover in the rat corpus striatum]. Acta biologica et medica Germanica. vol 34. issue 4. 1976-01-29. PMID:1189838. |
[cholinergic effect on the dopamine turnover in the rat corpus striatum]. |
1976-01-29 |
2023-08-11 |
rat |
| S Consolo, H Ladinsky, S Bianch. Decrease in rat striatal acetylcholine levels by some direct- and indirect-acting dopaminergic antagonists. European journal of pharmacology. vol 33. issue 2. 1976-01-26. PMID:1183479. |
these data suggest that haloperidol and pimozide act on the striatal cholinergic neurons through strong blockade of dopamine receptors. |
1976-01-26 |
2023-08-11 |
rat |
| P G Guyenet, J C Beaujouan, J Glowinsk. Ontogenesis of neostriatal cholinergic neurones in the rat and development of their sensitivity to neuroleptic drugs. Naunyn-Schmiedeberg's archives of pharmacology. vol 288. issue 2-3. 1975-12-04. PMID:1161052. |
these data confirm and extend previous reports that rat striatal cholinergic neurones are immature at birth; they suggest, in addition, that the development of dopamine receptors occurs prior to the appearance of functional cholinergic synapses or concomitant with this event. |
1975-12-04 |
2023-08-11 |
rat |
| B Costall, R J Naylo. Cholinergic modification of abnormal involuntary movements induced in the guinea-pig by intrastriatal dopamine. The Journal of pharmacy and pharmacology. vol 27. issue 4. 1975-11-06. PMID:239121. |
cholinergic modification of abnormal involuntary movements induced in the guinea-pig by intrastriatal dopamine. |
1975-11-06 |
2023-08-11 |
Not clear |
| P M Lalley, G V Rossi, W W Bake. Tremor production by intracaudate injections of morphine. European journal of pharmacology. vol 32. issue 1. 1975-11-06. PMID:1149825. |
tremor production by morphine is attributed to a reduction in dopamine function which allows cholinergic activity in the caudate nucleus to predominate. |
1975-11-06 |
2023-08-11 |
Not clear |
| R Lienhart, W Lichtensteiger, H Langeman. Response of nigral dopamine neurons to actue and prolonged morphine treatment: effect of exposure to cold, physostigmine and nicotine. Naunyn-Schmiedeberg's archives of pharmacology. vol 286. issue 4. 1975-10-10. PMID:1143352. |
the effects of morphine and acute exposure to cold on nigral dopamine (da) neurons and possible interactions with cholinergic systems were studied by histochemical microfluorimetry in normal and partially morphine-tolerant mice. |
1975-10-10 |
2023-08-11 |
mouse |
| P G Guyenet, F Javoy, Y Agid, J C Beaujouan, J Glowinsk. Dopamine receptors and cholinergic neurons in the rat neostriatum. Advances in neurology. vol 9. 1975-10-07. PMID:238376. |
dopamine receptors and cholinergic neurons in the rat neostriatum. |
1975-10-07 |
2023-08-11 |
rat |
| W Lichtensteiger, P J Kelle. Tubero-infundibular dopamine neurons and the secretion of luteinizing hormone and prolactin: extrahypothalamic influences, interaction with cholinergic systems and the effect of urethane anesthesia. Brain research. vol 74. issue 2. 1974-08-30. PMID:4836627. |
tubero-infundibular dopamine neurons and the secretion of luteinizing hormone and prolactin: extrahypothalamic influences, interaction with cholinergic systems and the effect of urethane anesthesia. |
1974-08-30 |
2023-08-11 |
Not clear |
| U Bretz, M Baggiolini, R Hauser, C Hode. Resolution of three distinct populations of nerve endings from rat brain homogenates by zonal isopycnic centrifugation. The Journal of cell biology. vol 61. issue 2. 1974-07-15. PMID:4363959. |
these three particle populations are likely to represent, in order of increasing modal equilibrium density, (a) cholinergic nerve endings, characterized by their high content of acetylcholine, (b) gamma-amino butyric acid (gaba)-containing nerve endings with high glutamate decarboxylase activity and the ability to accumulate exogenous gaba, (c) adrenergic nerve endings that accumulate exogenous dopamine and noradrenaline and exhibit high monoamine oxidase activity. |
1974-07-15 |
2023-08-11 |
rat |
| B Libet, C Owma. Concomitant changes in formaldehyde-induced fluorescence of dopamine interneurones and in slow inhibitory post-synaptic potentials of the rabbit superior cervical ganglion, induced by stimulation of the preganglionic nerve or by a muscarinic agent. The Journal of physiology. vol 237. issue 3. 1974-06-26. PMID:4825476. |
it is concluded that (a) preganglionic impulses, by a cholinergic muscarinic synaptic action, can induce a release of dopamine from dopamine interneurones (small intensely fluorescent cells) in the superior cervical ganglion, (b) the ability of the ganglion to respond with a s.-i.p.s.p. |
1974-06-26 |
2023-08-11 |
rabbit |