| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M R Mickelson, I V Ponseti, R R Cooper, J A Maynar. The ultrastructure of the growth plate in slipped capital femoral epiphysis. The Journal of bone and joint surgery. American volume. vol 59. issue 8. 1978-02-18. PMID:591539. |
the cartilage matrix in the zones of chondrocyte hypertrophy where the slippage occurred contained only scattered fine collagen fibrils in a homogeneous ground substance. |
1978-02-18 |
2023-08-11 |
Not clear |
| R E Wuthier, R J Majeska, G M Collin. Biosynthesis of matrix vesicles in epiphyseal cartilage. I. In vivo incorporation of 32P orthophosphate into phospholipids of chondroxyte, membrane, and matrix vesicle fractions. Calcified tissue research. vol 23. issue 2. 1977-10-14. PMID:890550. |
support for this comes from previous data which revealed that substantial phospholipase activity is present in epiphyseal cartilage, especially in the zone of hypertrophy where matrix vesicle formation appears to be particularly active. |
1977-10-14 |
2023-08-11 |
chicken |
| E M Parshkov, R A Brodskiĭ, N A Pogudin. [Ultrastructure of the enterocytes of the upper 3d of the villi of murine small intestine]. Tsitologiia. vol 18. issue 11. 1977-09-17. PMID:1029124. |
it was found that enterocytes moving to the top of the villus underwent regular structural rearrangements that involve the appearance of triangular dilatations of the intercellular spaces at the cell base, condensation of the mitochondrial matrix, reduction of ergastoplasmic reticulum and dictyosome hypertrophy. |
1977-09-17 |
2023-08-11 |
mouse |
| R W Orkin, B R Williams, R E Cranley, D C Poppke, K S Brow. Defects in the cartilaginous growth plates of brachymorphic mice. The Journal of cell biology. vol 73. issue 2. 1977-06-30. PMID:67117. |
the ultrastructural appearance of the cartilage matrix indicates normal collagen fibrils; however, proteoglycan aggregate granules are smaller than normal and are present in reduced numbers, particularly in the columnar and hypertrophic zones of the growth plate. |
1977-06-30 |
2023-08-11 |
mouse |
| R D Hunt, M J Van Zwieten, R B Baggs, P K Sehgal, N W King, S M Roach, B J Blak. Glomerulonephritis in the owl monkey (Aotus trivirgatus). Laboratory animal science. vol 26. issue 6 Pt 2. 1977-04-30. PMID:828227. |
the lesions were characterized by proliferation and hypertrophy of mesangial and epithelial cells, increase in mesangial matrix, thickening of basement membranes, and sclerosis. |
1977-04-30 |
2023-08-11 |
monkey |
| K Kawamura, C Kashii, K Imamur. Ultrastructural changes in hypertrophied myocardium of spontaneously hypertensive rats. Japanese circulation journal. vol 40. issue 10. 1977-01-25. PMID:136527. |
in 21-week-old shr, in addition to findings similar to those in 15-week-old shr, heterogeneous changes of the contractile material, mitochondria and sarcoplasmic matrix were more prominent, suggesting heterogeneous malfunctions in later stages of cardiac hypertrophy. |
1977-01-25 |
2023-08-11 |
rat |
| F H Wezema. 25-hydroxyvitamin D: autoradiographic evidence of sites of action in epiphyseal cartilage and bone. Science (New York, N.Y.). vol 194. issue 4269. 1977-01-03. PMID:982062. |
highly selective incorporation occurred in epiphyseal hypertrophic cells, epiphyseal matrix, osteoid, osteoblasts, and osteocytes of metaphyseal bone spicules. |
1977-01-03 |
2023-08-11 |
rat |
| F H Wezema. 25-hydroxyvitamin D: autoradiographic evidence of sites of action in epiphyseal cartilage and bone. Science (New York, N.Y.). vol 194. issue 4269. 1977-01-03. PMID:982062. |
the labeled metabolite appeared in chondrocytic lacunar matrix coincident with hypertrophic cell death as evidenced by histological examination. |
1977-01-03 |
2023-08-11 |
rat |
| M N Pavlova, V A Duliapi. [Ultrastructural changes in articular cartilage in rheumatoid arthritis]. Arkhiv patologii. vol 38. issue 8. 1977-01-03. PMID:985134. |
a reparative regeneration of the disintegrating matrix was realized mainly because of hypertrophy of the functionally preserved chondrocytes. |
1977-01-03 |
2023-08-11 |
Not clear |
| S Y Al. Analysis of matrix vesicles and their role in the calcification of epiphyseal cartilage. Federation proceedings. vol 35. issue 2. 1976-04-15. PMID:1248646. |
adjoinging nonvesicular matrix in the hypertrophic zone, cell cytoplasm, and cell processes had very low levels of calcium and phosphorus in a region where matrix vesicles showed high levels of these elements. |
1976-04-15 |
2023-08-11 |
Not clear |
| S Singh, D N Sinha, G C Prasa. Autoradiographic study of chick limb cartilage in vivo and in vitro and its response to mitomycin C (MMC). Acta anatomica. vol 93. issue 3. 1976-03-05. PMID:128983. |
hypertrophy of cartilage cells at later stages reduced the matrix, leading to a corresponding decrease in the accumulation of silver grains. |
1976-03-05 |
2023-08-11 |
chicken |
| S Singh, D N Sinha, G C Prasa. Autoradiographic study of chick limb cartilage in vivo and in vitro and its response to mitomycin C (MMC). Acta anatomica. vol 93. issue 3. 1976-03-05. PMID:128983. |
in the treated groups, both in vivo and in vitro, the silver grains were found to be less in number during the initial stage of growth than in the corresponding controls, due to the suppressive effect of the mitomycin c. however, during the later period of growth, uptake of 35s was more in the matrix of treated specimens, which was apparently not reduced due to lack of hypertrophy of cartilage cells. |
1976-03-05 |
2023-08-11 |
chicken |
| Z Bozdĕch, V Hor. The morphology of growth cartilage using the scanning electron microscope. Acta orthopaedica Scandinavica. vol 46. issue 4. 1975-12-23. PMID:1180019. |
especially interesting are the regressive processes in both the cells and the matrix which explain the reduction of mechanical strength in the zone of the hypertrophic cells. |
1975-12-23 |
2023-08-11 |
rabbit |
| H C Anderson, R Cecil, S W Sajder. Calcification of rachitic rat cartilage in vitro by extracellular matrix vesicles. The American journal of pathology. vol 79. issue 2. 1975-09-26. PMID:1146961. |
under these conditions, mineralization was prominent in the upper hypertrophic cartilage, where matrix vesicles became encrusted with apatite after only 2 to 3 hours of incubation. |
1975-09-26 |
2023-08-11 |
rat |
| U N Riede, W Villiger, M Mihatsch, E Anabitarte, K Schäre. [Ultrastructural studies on an animal model of epiphyseolysis. Cells and matrix in the proximal growth plate of the rat tibia after administration of DL-serine(3,4,5-trihydroxybenzyl)-hydrazide] (author's transl) Virchows Archiv. B, Cell pathology. vol 17. issue 4. 1975-09-09. PMID:806163. |
cells and matrix in the proximal growth plate of the rat tibia after administration of dl-serine(3,4,5-trihydroxybenzyl)-hydrazide] (author's transl) after administration of dl-serine-(2,3,4-trihydroxybenzyl-)hydrazide, the growth plate of rat tibia, and most of all the zone of hypertrophic cartilage, is much widened. |
1975-09-09 |
2023-08-11 |
rat |
| M C Meikl. The distribution and function of lysosomes in condylar cartilage. Journal of anatomy. vol 119. issue Pt 1. 1975-09-03. PMID:1133092. |
the large numbers of lysosomes in the hypertrophic chondrocytes, however, are probably more concerned in bringing about autolysis of the cells than in promoting calcification of the matrix. |
1975-09-03 |
2023-08-11 |
Not clear |
| R Eisenstein, S E Larsson, N Sorgente, K E Kuettne. Collagen-proteoglycan relationships in epiphyseal cartilage. The American journal of pathology. vol 73. issue 2. 1974-01-31. PMID:4357177. |
columnar and hypertrophic zones of calf scapular cartilage were studied before and after extraction with 3 m guanidinium chloride (gucl) and digestion with enzymes which degrade various components of the extracellular matrix. |
1974-01-31 |
2023-08-11 |
Not clear |
| J C Pita, L A Cuervo, J E Madruga, F J Muller, D S Howel. Evidence for a role of proteinpolysaccharides in regulation of mineral phase separation in calcifying cartilage. The Journal of clinical investigation. vol 49. issue 12. 1971-01-11. PMID:4921198. |
our previous studies have indicated the presence of a macromolecular inhibitor of in vitro mineral growth, as well as a mineral nucleational agent in extracellular matrix fluid aspirated by micropuncture methods from epiphyseal hypertrophic cell cartilage. |
1971-01-11 |
2023-08-11 |
Not clear |
| H C Anderso. Vesicles associated with calcification in the matrix of epiphyseal cartilage. The Journal of cell biology. vol 41. issue 1. 1969-05-08. PMID:5775794. |
a close association was demonstrated between matrix vesicles and calcification: in the lower hypertrophic and calcifying zones of the epiphysis, vesicles were found in juxtaposition to needle-like structures removed by demineralization with ethylenediaminetetraacetate and identified by electron diffraction as hydroxyapatite and/or fluorapatite crystal structure-the former being indistinguishable from the latter for most cases in which electron diffraction methods are employed. |
1969-05-08 |
2023-08-12 |
mouse |