| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dumitru A Iacobas, Haile Allen, Sanda Iacoba. Low-Salt Diet Regulates the Metabolic and Signal Transduction Genomic Fabrics, and Remodels the Cardiac Normal and Chronic Pathological Pathways. Current issues in molecular biology. vol 46. issue 3. 2024-03-27. PMID:38534766. |
moreover, lsd remodeled pathways responsible for cardiac muscle contraction (cmc), chronic chagas (cha), diabetic (dia), dilated (dil), and hypertrophic (hcm) cardiomyopathies, and their interplays with the glycolysis/glucogenesis (gly), oxidative phosphorylation (oxp), and adrenergic signaling in cardiomyocytes (asc). |
2024-03-27 |
2024-03-29 |
mouse |
| Bing Xiao, Yan Zhao, Ke Ke Wang, Xiu Chun Yang, Hai Juan Hu, Yue Li, Yun Fei Xu, Zhen Tian Zhang, Shuai Wang, Jing Chao L. Inhibition of the STIM1/Orai1 Signaling Pathway by Glycine Betaine Mitigates Myocardial Hypertrophy in Spontaneous Hypertension Rats. Cardiology research. vol 14. issue 6. 2024-01-08. PMID:38187515. |
inhibition of the stim1/orai1 signaling pathway by glycine betaine mitigates myocardial hypertrophy in spontaneous hypertension rats. |
2024-01-08 |
2024-01-10 |
rat |
| Giuseppe Vacchiano, Aldo Rocca, Rita Compagna, Anna Ginevra Immacolata Zamboli, Vera Cirillo, Lorenza Di Domenico, Veronica Di Nardo, Giuseppe Servillo, Bruno Amat. Transurethral Resection of the Prostate, Bladder Explosion and Hyponatremic Encephalopathy: A Rare Case Report of Malpractice. Open medicine (Warsaw, Poland). vol 12. 2020-10-01. PMID:28435905. |
we present an original case report of a bladder explosion during a turp intervention for benign prostatic hypertrophy, that was brought on by the absorption of about 5 liters of glycine 1.5% and then onset of a severe hyponatremia. |
2020-10-01 |
2023-08-13 |
Not clear |
| Meilu Dai, Baiyan Sui, Yang Xue, Xin Liu, Jiao Su. Cartilage repair in degenerative osteoarthritis mediated by squid type II collagen via immunomodulating activation of M2 macrophages, inhibiting apoptosis and hypertrophy of chondrocytes. Biomaterials. vol 180. 2019-09-30. PMID:30031224. |
in addition, glycine in scii activates glycine receptors on inflammatory chondrocytes to decrease intracellular calcium concentration, leading to effective inhibition of chondrocyte apoptosis and hypertrophy. |
2019-09-30 |
2023-08-13 |
rat |
| Mehroz Ehsan, Matthew Kelly, Charlotte Hooper, Arash Yavari, Julia Beglov, Mohamed Bellahcene, Kirandeep Ghataorhe, Giulia Poloni, Anuj Goel, Theodosios Kyriakou, Karin Fleischanderl, Elisabeth Ehler, Eugene Makeyev, Stephan Lange, Houman Ashrafian, Charles Redwood, Benjamin Davies, Hugh Watkins, Katja Gehmlic. Mutant Muscle LIM Protein C58G causes cardiomyopathy through protein depletion. Journal of molecular and cellular cardiology. vol 121. 2019-09-10. PMID:30048712. |
cysteine and glycine rich protein 3 (csrp3) encodes muscle lim protein (mlp), a well-established disease gene for hypertrophic cardiomyopathy (hcm). |
2019-09-10 |
2023-08-13 |
mouse |
| XueJiang Cen, JianLei Zheng, XueLie Hu, BaiMing Q. Severe apical hypertrophic cardiomyopathy with Ser 236 Gly mutation in MYBPC3: A three-year follow-up investigation. Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese. vol 58. issue 5. 2018-08-22. PMID:28062247. |
severe apical hypertrophic cardiomyopathy with ser 236 gly mutation in mybpc3: a three-year follow-up investigation. |
2018-08-22 |
2023-08-13 |
Not clear |
| Yan Lu, Xudong Zhu, Jinjie Li, Ru Fang, Zhuoyun Wang, Jing Zhang, Kexue Li, Xiaoyu Li, Hui Bai, Qing Yang, Jingjing Ben, Hanwen Zhang, Qi Che. Glycine prevents pressure overload induced cardiac hypertrophy mediated by glycine receptor. Biochemical pharmacology. vol 123. 2017-05-12. PMID:27836671. |
the aim of this study was to determine the effects of glycine on pathologic cardiac hypertrophy and the mechanism underlying it. |
2017-05-12 |
2023-08-13 |
rat |
| Yan Lu, Xudong Zhu, Jinjie Li, Ru Fang, Zhuoyun Wang, Jing Zhang, Kexue Li, Xiaoyu Li, Hui Bai, Qing Yang, Jingjing Ben, Hanwen Zhang, Qi Che. Glycine prevents pressure overload induced cardiac hypertrophy mediated by glycine receptor. Biochemical pharmacology. vol 123. 2017-05-12. PMID:27836671. |
these results, for the first time, demonstrate that glycine may be a novel cardioprotector against pressure overload induced cardiac hypertrophy. |
2017-05-12 |
2023-08-13 |
rat |
| Yan Lu, Xudong Zhu, Jinjie Li, Ru Fang, Zhuoyun Wang, Jing Zhang, Kexue Li, Xiaoyu Li, Hui Bai, Qing Yang, Jingjing Ben, Hanwen Zhang, Qi Che. Glycine prevents pressure overload induced cardiac hypertrophy mediated by glycine receptor. Biochemical pharmacology. vol 123. 2017-05-12. PMID:27836671. |
glycine prevents pressure overload induced cardiac hypertrophy mediated by glycine receptor. |
2017-05-12 |
2023-08-13 |
rat |
| Yan Lu, Xudong Zhu, Jinjie Li, Ru Fang, Zhuoyun Wang, Jing Zhang, Kexue Li, Xiaoyu Li, Hui Bai, Qing Yang, Jingjing Ben, Hanwen Zhang, Qi Che. Glycine prevents pressure overload induced cardiac hypertrophy mediated by glycine receptor. Biochemical pharmacology. vol 123. 2017-05-12. PMID:27836671. |
thus, glycine would be useful in the prevention of cardiac hypertrophy and heart failure. |
2017-05-12 |
2023-08-13 |
rat |
| Yan Lu, Xudong Zhu, Jinjie Li, Ru Fang, Zhuoyun Wang, Jing Zhang, Kexue Li, Xiaoyu Li, Hui Bai, Qing Yang, Jingjing Ben, Hanwen Zhang, Qi Che. Glycine prevents pressure overload induced cardiac hypertrophy mediated by glycine receptor. Biochemical pharmacology. vol 123. 2017-05-12. PMID:27836671. |
pre-treatment with glycine significantly attenuated murine cardiac hypertrophy induced by transverse aortic constriction or by administration of angiotensin ii (ang ii). |
2017-05-12 |
2023-08-13 |
rat |
| Rafael Zanelli Rissoli, Fabio Camargo Abdalla, Monica Jones Costa, Francisco Tadeu Rantin, David John McKenzie, Ana Lucia Kalini. Effects of glyphosate and the glyphosate based herbicides Roundup Original(®) and Roundup Transorb(®) on respiratory morphophysiology of bullfrog tadpoles. Chemosphere. vol 156. 2017-03-17. PMID:27160633. |
gly significantly reduced v·o2, possibly due to epidermal hypertrophy, which increased o2 diffusion distance to o2 uptake. |
2017-03-17 |
2023-08-13 |
Not clear |
| Yazmín Reyes López, Israel Pérez-Torres, Alejandra Zúñiga-Muñoz, Verónica Guarner Lans, Eulises Díaz-Díaz, Elizabeth Soria Castro, Rodrigo Velázquez Espeje. Effect of Glycine on Adipocyte Hypertrophy in a Metabolic Syndrome Rat Model. Current drug delivery. vol 13. issue 1. 2016-12-13. PMID:26996629. |
here we evaluate the effect of 1% gly in the diet on adipocyte hypertrophy and the modulation of lipoprotein lipase (lpl) and hormone-sensitive lipase (hsl) in a metabolic syndrome (ms) rat model with intra-abdominal obesity. |
2016-12-13 |
2023-08-13 |
rat |
| Yazmín Reyes López, Israel Pérez-Torres, Alejandra Zúñiga-Muñoz, Verónica Guarner Lans, Eulises Díaz-Díaz, Elizabeth Soria Castro, Rodrigo Velázquez Espeje. Effect of Glycine on Adipocyte Hypertrophy in a Metabolic Syndrome Rat Model. Current drug delivery. vol 13. issue 1. 2016-12-13. PMID:26996629. |
effect of glycine on adipocyte hypertrophy in a metabolic syndrome rat model. |
2016-12-13 |
2023-08-13 |
rat |
| Yazmín Reyes López, Israel Pérez-Torres, Alejandra Zúñiga-Muñoz, Verónica Guarner Lans, Eulises Díaz-Díaz, Elizabeth Soria Castro, Rodrigo Velázquez Espeje. Effect of Glycine on Adipocyte Hypertrophy in a Metabolic Syndrome Rat Model. Current drug delivery. vol 13. issue 1. 2016-12-13. PMID:26996629. |
gly in ms rats decreased body weight, intra-abdominal adipose tissue, adipocyte hypertrophy, blood pressure, triglycerides, insulin, homa-ir index, leptin, total fatty acids, non-esterified fatty acids and lpl activity. |
2016-12-13 |
2023-08-13 |
rat |
| Yazmín Reyes López, Israel Pérez-Torres, Alejandra Zúñiga-Muñoz, Verónica Guarner Lans, Eulises Díaz-Díaz, Elizabeth Soria Castro, Rodrigo Velázquez Espeje. Effect of Glycine on Adipocyte Hypertrophy in a Metabolic Syndrome Rat Model. Current drug delivery. vol 13. issue 1. 2016-12-13. PMID:26996629. |
glycine (gly) lowers hypercholesterolemia, hypertriglyceridemia and hypertension but its role in preventing adipocyte hypertrophy and modulating enzymatic activity of adipocytes has not been studied. |
2016-12-13 |
2023-08-13 |
rat |
| Priya Muthu, Li Wang, Chen-Ching Yuan, Katarzyna Kazmierczak, Wenrui Huang, Olga M Hernandez, Masataka Kawai, Thomas C Irving, Danuta Szczesna-Cordar. Structural and functional aspects of the myosin essential light chain in cardiac muscle contraction. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 25. issue 12. 2012-02-28. PMID:21885653. |
here, we generated transgenic (tg) mice expressing the a57g (alanine to glycine) mutation in the cardiac elc known to cause familial hypertrophic cardiomyopathy (fhc). |
2012-02-28 |
2023-08-12 |
mouse |
| Yoshifumi Takahata, Takeshi Takarada, Masato Osawa, Eiichi Hinoi, Yukari Nakamura, Yukio Yoned. Differential regulation of cellular maturation in chondrocytes and osteoblasts by glycine. Cell and tissue research. vol 333. issue 1. 2008-12-04. PMID:18427837. |
exposure to gly drastically increased mrna expression of the calcified chondrocyte marker osteopontin, without markedly affecting that of a proliferating chondrocyte marker or a hypertrophic chondrocyte marker, as shown in organotypic cultures by in situ hybridization analysis. |
2008-12-04 |
2023-08-12 |
mouse |
| Joanna K Davies, Dominic J Wells, Ke Liu, Helen R Whitrow, Tyrone D Daniel, Robert Grignani, Craig A Lygate, Jürgen E Schneider, Gaëtane Noël, Hugh Watkins, David Carlin. Characterization of the role of gamma2 R531G mutation in AMP-activated protein kinase in cardiac hypertrophy and Wolff-Parkinson-White syndrome. American journal of physiology. Heart and circulatory physiology. vol 290. issue 5. 2006-06-01. PMID:16339829. |
here we report that transgenic mice with cardiac-specific expression of gamma2 harboring a mutation of arginine residue 531 to glycine (rg-tg) develop a striking cardiac phenotype by 4 wk of age, including hypertrophy, impaired contractile function, electrical conduction abnormalities, and marked glycogen accumulation. |
2006-06-01 |
2023-08-12 |
mouse |
| Dirk Wernicke, Corinna Thiel, Corina M Duja-Isac, Kirill V Essin, Matthias Spindler, Derek J R Nunez, Ralph Plehm, Niels Wessel, Annette Hammes, Robert-J Edwards, Andrea Lippoldt, Ute Zacharias, Hinrik Strömer, Stefan Neubauer, Michael J Davies, Ingo Morano, Ludwig Thierfelde. alpha-Tropomyosin mutations Asp(175)Asn and Glu(180)Gly affect cardiac function in transgenic rats in different ways. American journal of physiology. Regulatory, integrative and comparative physiology. vol 287. issue 3. 2004-09-10. PMID:15031138. |
to study the mechanisms by which missense mutations in alpha-tropomyosin cause familial hypertrophic cardiomyopathy, we generated transgenic rats overexpressing alpha-tropomyosin with one of two disease-causing mutations, asp(175)asn or glu(180)gly, and analyzed phenotypic changes at molecular, morphological, and physiological levels. |
2004-09-10 |
2023-08-12 |
rat |